DemitriPapolosMD

Psychiatry • Westport, CT

Child & Adolescent Psychiatry, Neuropsychiatry

Director of Research Juvenile Bipolar Research Foundation

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Office
120 Post Rd West
Suite 301
Westport, CT 06880
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Education & Training

New York Presbyterian Hospital (Columbia Campus)/New York State Psychiatric InstituteResidency, Psychiatry, 1977 - 1980
New York Medical College (Metropolitan)Residency, Internal Medicine, 1976 - 1977
New York Medical CollegeClass of 1976

Certifications & Licensure

FL State Medical License 2022 - 2025
NY State Medical License 1977 - 2024
CT State Medical License 1993 - 2023
American Board of Psychiatry and Neurology Psychiatry

Publications & Presentations

PubMed

10 citations
Clinical experience using intranasal ketamine in the longitudinal treatment of juvenile bipolar disorder with fear of harm phenotype.
Demitri F. Papolos, Mark G. Frei, Daniel Rossignol, Steven Mattis, Laura C. Hernandez-Garcia, Martin H. Teicher> ;Journal of Affective Disorders. 2018 Jan 1
7 citations
Alterations in Skin Temperature and Sleep in the Fear of Harm Phenotype of Pediatric Bipolar Disorder
Patricia J. Murphy, Mark G. Frei, Demitri Papolos> ;Journal of Clinical Medicine. 2014 Aug 22
4 citations
Bipolar disorder in children: assessment in general pediatric practice.
Demitri F. Papolos, Alissa Bronsteen> ;Current Opinion in Pediatrics. 2013 Jun 1
44 citations
Clinical experience using intranasal ketamine in the treatment of pediatric bipolar disorder/fear of harm phenotype.
Demitri F. Papolos, Martin H. Teicher, Gianni L. Faedda, Patricia Murphy, Steven Mattis> ;Journal of Affective Disorders. 2013 May 1
14 citations
Neuropsychological factors differentiating treated children with pediatric bipolar disorder from those with attention-deficit/hyperactivity disorder.
Steven Mattis, Demitri F. Papolos, Dana Luck, Melissa S. Cockerham, Henry C. Thode> ;Journal of Clinical and Experimental Neuropsychology. 2011 Jan 1
18 citations
Fear of harm, a possible phenotype of pediatric bipolar disorder: a dimensional approach to diagnosis for genotyping psychiatric syndromes.
Demitri F. Papolos, Steven Mattis, Shahrokh Golshan, Francine Molay> ;Journal of Affective Disorders. 2009 Nov 1
95 citations
Increase in GSK3β gene copy number variation in bipolar disorder
Herbert M. Lachman, Erika Pedrosa, Oriana A. Petruolo, Melissa S. Cockerham, Alexander Papolos, Tomas Novak, Demitri F. Papolos, Pavla Stopkova> ;American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics. 2007 Apr 5
16 citations
A strategy for identifying phenotypic subtypes: concordance of symptom dimensions between sibling pairs who met screening criteria for a genetic linkage study of child...
Demitri F. Papolos, John Hennen, Melissa S. Cockerham, Herbert M. Lachman> ;Journal of Affective Disorders. 2007 Apr 1
23 citations
The child bipolar questionnaire: a dimensional approach to screening for pediatric bipolar disorder
Demitri F. Papolos, John Hennen, Melissa S. Cockerham, Henry C. Thode, Eric A. Youngstrom> ;Journal of Affective Disorders. 2006 Oct 1
19 citations
Analysis of synapsin III-196 promoter mutation in schizophrenia and bipolar disorder.
Herbert M. Lachman, Pavla Stopkova, Demitri F. Papolos, Erika Pedrosa, Benjamin Margolis, Maryam Rafael Aghalar, Takuya Saito> ;Neuropsychobiology. 2006 Jan 1
9 citations
Obsessive fears about harm to self or others and overt aggressive behaviors in youth diagnosed with juvenile-onset bipolar disorder.
Demitri F. Papolos, John Hennen, Melissa S. Cockerham> ;Journal of Affective Disorders. 2005 Dec 1
17 citations
Screening of PIP5K2A promoter region for mutations in bipolar disorder and schizophrenia.
Pavla Stopkova, Jan Vevera, Ivo Paclt, Ilja Zukov, Demitri F. Papolos, Takuya Saito, Herbert M. Lachman> ;Psychiatric Genetics. 2005 Sep 1
24 citations
Factors associated with parent-reported suicide threats by children and adolescents with community-diagnosed bipolar disorder
Demitri F. Papolos, John Hennen, Melissa S. Cockerham> ;Journal of Affective Disorders. 2005 Jun 1
70 citations
Identification of PIK3C3 promoter variant associated with bipolar disorder and schizophrenia.
Pavla Stopkova, Takuya Saito, Demitri F. Papolos, Jan Vevera, Ivo Paclt, Ilja Zukov, Yonina B Bersson, Benjamin Margolis, Rael D. Strous, Herbert M. Lachman> ;Biological Psychiatry. 2004 May 15
40 citations
Polymorphism Screening of PIP5K2A: A Candidate Gene for Chromosome 10p-Linked Psychiatric Disorders
Pavla Stopkova, Takuya Saito, Cathy S.J. Fann, Demitri F. Papolos, Jan Vevera, Ivo Paclt, Ilja Zukov, Rafael Stryjer, Rael D. Strous, Herbert M. Lachman> ;American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics. 2003 Nov 15
23 citations
Polymorphism screening of PIK4CA: possible candidate gene for chromosome 22q11-linked psychiatric disorders.
Takuya Saito, Pavla Stopkova, Libna Diaz, Demitri F. Papolos, Lise Boussemart, Herbert M. Lachman> ;American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics. 2003 Jan 1
7 citations
Switching, cycling, and antidepressant-induced effects on cycle frequency and course of illness in adult bipolar disorder: a brief review and commentary.
Demitri F. Papolos> ;Journal of Child and Adolescent Psychopharmacology. 2003 Jan 1
42 citations
Mutation analysis of SYNJ1 : a possible candidate gene for chromosome 21q22-linked bipolar disorder
Takuya Saito, F Guan, Demitri F. Papolos, S Lau, M Klein, Cathy S.J. Fann, Herbert M. Lachman> ;Molecular Psychiatry. 2001 Jul 1
35 citations
Polymorphism in SNAP29 gene promoter region associated with schizophrenia.
Takuya Saito, F Guan, Demitri F. Papolos, N. Rajouria, Cathy S.J. Fann, Herbert M. Lachman> ;Molecular Psychiatry. 2001 Mar 1
30 citations
Analysis of the pseudoautosomal X-linked gene SYBL1in bipolar affective disorder: description of a new candidate allele for psychiatric disorders.
Takuya Saito, Sam S. Parsia, Demitri F. Papolos, Herbert M. Lachman> ;American Journal of Medical Genetics. 2000 Jun 12
18 citations
Analysis of GNAZ gene polymorphism in bipolar affective disorder.
Takuya Saito, Demitri F. Papolos, Danielle Chernak, Mark Hyman Rapaport, John R. Kelsoe, Herbert M. Lachman> ;American Journal of Medical Genetics. 1999 Aug 20
118 citations
Ultra-ultra rapid cycling bipolar disorder is associated with the low activity catecholamine-O- methyltransferase allele
Demitri F. Papolos, S Veit, Gianni L. Faedda, Takuya Saito, Herbert M. Lachman> ;Molecular Psychiatry. 1998 Jul 1
2 citations
Chromosome 22q11 deletions and aggressive behaviour.
Herbert M. Lachman, Demitri F. Papolos> ;The British Journal of Psychiatry. 1998 Jun 1
73 citations
Linkage studies suggest a possible locus for bipolar disorder near the velo-cardio-facial syndrome region on chromosome 22.
Herbert M. Lachman, John R. Kelsoe, Ronald A. Remick, A. Dessa Sadovnick, Mark Hyman Rapaport, Margaret J. Lin, Beverly A. Pazur, Anne Marie Roe, Takuya Saito, Demitri...> ;American Journal of Medical Genetics. 1997 Apr 18
104 citations
Molecular analysis of velo-cardio-facial syndrome patients with psychiatric disorders.
C. Carlson, Demitri F. Papolos, Raj K. Pandita, Gianni L. Faedda, S. Veit, Rosalie Goldberg, Robert J. Shprintzen, Raju Kucherlapati, Bernice E. Morrow> ;American Journal of Human Genetics. 1997 Apr 1
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Press Mentions

FDA Approves Anti-Depressant Nasal Spray Based on Ketamine Party DrugNovember 30th, 2019
FDA Approves Esketamine Nasal Spray for Hard-to-Treat DepressionMarch 6th, 2019
From Chaos to Calm: A Life Changed by KetamineJune 8th, 2018
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