DennisAWigleMD

Thoracic Surgery • Rochester, MN

Assistant Professor, Surgery, Mayo Medical School

Join to view full profile

Dr. Wigle is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Connect with other colleagues in the same hospital or clinic
Search all U.S. specialist profiles and refer a patient
Read the latest clinical news and earn CME/CEU credits

See Dr. Wigle's full profile

Already have an account?

Office
200 1st Street SW
Rochester, MN 55905
Is this information wrong?

Education & Training

University of Toronto Faculty of MedicineClass of 1997

Certifications & Licensure

AZ State Medical License 2019 - 2025
MN State Medical License 2006 - 2025

Awards, Honors, & Recognition

Fellow (FACS) American College of Surgeons

Clinical Trials

Pioglitazone Hydrochloride in Treating Patients With Stage IA-IIIA Non-small Cell Lung Cancer Start of enrollment: 2011 Apr 01
Terminated
Phase 2
Stereotactic Body Radiotherapy (SBRT) Versus Sublobar Resection for High-Risk Patients Non-Small Lung Cancer Start of enrollment: 2012 May 01
Terminated
Phase 2
Metformin as a Chemoprevention Agent in Non-small Cell Lung Cancer Start of enrollment: 2012 Oct 01
Terminated
Phase 2
Validation of the MiCK Assay Start of enrollment: 2012 Jun 01
Terminated
A Phase I Study of iPS Cell Generation From Patients With COPD Start of enrollment: 2009 Sep 01
Completed
Not Applicable
Treatment of Multifocal Lung Adenocarcinoma Start of enrollment: 2013 Oct 01
Active, not recruiting
Not Applicable
Identification of Prognostic Biomarkers for Progression of Invasive Squamous Cell Carcinoma Start of enrollment: 2015 Aug 01
Recruiting
Surgery for Mesothelioma After Radiation Therapy "SMART" for Resectable Malignant Pleural Mesothelioma Start of enrollment: 2015 Nov 01
Recruiting
Chemotherapy Followed by Surgery and Neoadjuvant Hemothoracic Intensity Modified Radiation Therapy (IMRT) for Patients With Malignant Pleural Mesothelioma Start of enrollment: 2016 Mar 18
Recruiting
Staging Procedures to Diagnose Malignant Pleural Mesothelioma Start of enrollment: 2016 Mar 14
Recruiting
Measuring Cell Free DNA During the Course of Treatment for Esophageal Cancer as a Marker of Response and Recurrence Start of enrollment: 2017 Oct 01
Terminated
Progenitor Cells in Human Esophagus Start of enrollment: 2017 Jun 29
Completed
Join now to see all

Publications & Presentations

PubMed

1 citations
An in-silico analysis reveals further evidence of an aggressive subset of lung carcinoids sharing molecular features of high-grade neuroendocrine neoplasms.
Giuseppe Pelosi, Valentina Melocchi, Elisa Dama, Paul Hofman, Marco De Luca, Adriana Albini, Maria Gemelli, Riccardo Ricotta, Mauro Papotti, Stefano La Rosa, Silvia Uc...> ;Experimental and Molecular Pathology. 2024 Feb 1
Sublobar Resection, Stereotactic Body Radiation Therapy, and Percutaneous Ablation Provide Comparable Outcomes for Lung Metastasis-Directed Therapy.
Hunter C Gits, Mitra A Khosravi Flanigan, Jamie D Kapplinger, Janani S Reisenauer, Patrick W Eiken, William G Breen, Linh H Vu, Brian T Welch, William S Harmsen, Court...> ;Chest. 2023 Dec 14
Esophagectomy Enhanced Recovery After Surgery Initiative Results in Improved Outcomes.
Charles R Sims 3rd, Mohamad K Abou Chaar, Mitchell H Kerfeld, Stephen D Cassivi, Ryan E Hofer, Francis C Nichols, Janani Reisenauer, Sahar S Saddoughi, K Robert Shen, ...> ;The Annals of Thoracic Surgery. 2024 Apr 1
Progress in genome-inspired treatment decisions for multifocal lung adenocarcinoma.
Chelsea L Powell, Sahar A Saddoughi, Dennis A Wigle> ;Expert Review of Respiratory Medicine. 2023 Dec 26
1 citations
Determinants of Long-term Survival Decades After Esophagectomy for Esophageal Cancer.
Mohamad K Abou Chaar, Anny Godin, William S Harmsen, Camryn Wzientek, Sahar A Saddoughi, Christopher L Hallemeier, Stephen D Cassivi, Francis C Nichols, Janani S Reise...> ;The Annals of Thoracic Surgery. 2023 Nov 1
Impact of FDG PET Standardized Uptake Value in Resected Clinical Stage IA Non-Small Cell Lung Cancer.
Luis F Tapias, Robert Shen, Stephen D Cassivi, Janani S Reisenauer, Brendan W Lunn, Bettie J Lechtenberg, Francis C Nichols, Dennis A Wigle, Shanda H Blackmon> ;The Annals of Thoracic Surgery. 2024 May 1
Pulmonary Open, Robotic, and Thoracoscopic Lobectomy (PORTaL) Study: Survival Analysis of 6646 Cases.
Michael S Kent, Matthew G Hartwig, Eric Vallières, Abbas E Abbas, Robert J Cerfolio, Mark R Dylewski, Thomas Fabian, Luis J Herrera, Kimble G Jett, Richard S Lazzaro, ...> ;Annals of Surgery. 2023 Jun 1
3 citations
The Utility of the Omentum Flap for Complex Intrathoracic Problems.
Lucas Kreutz-Rodrigues, Waleed Gibreel, Steven L Moran, Samir Mardini, Uldis Bite, John M Stulak, Dennis Wigle, Alberto Pochettino, Karim Bakri> ;Plastic Surgery. 2023 Feb 1
Prognostic factors in resected pulmonary carcinoid tumors: A retrospective study with 10 years of follow‑up.
Lin Du, Vinicius Ernani, Alex Liu, Steven E Schild, Dawn E Jaroszewski, Steven D Cassivi, Staci E Beamer, Yung-Hung Luo, Jason A Wampfler, Pedro A Reck Dos Santos, Den...> ;Oncology Letters. 2023 Feb 1
1 citations
Risk stratification of postoperative cardiopulmonary toxicity after trimodality therapy for esophageal cancer.
Roman O Kowalchuk, Grant M Spears, Lindsay K Morris, Dawn Owen, Harry H Yoon, Krishan Jethwa, Michael D Chuong, Matthew J Ferris, Michael G Haddock, Christopher L Hall...> ;Frontiers in Oncology. 2023 Jan 1
20 citations
Pembrolizumab in Combination with Neoadjuvant Chemoradiotherapy for Patients with Resectable Adenocarcinoma of the Gastroesophageal Junction.
Mojun Zhu, Chunhua Chen, Nathan R Foster, Christopher Hartley, Taofic Mounajjed, Marcela A Salomao, Briant F Fruth, Staci E Beamer, Yohan Kim, Susan M Harrington, Henr...> ;Clinical Cancer Research. 2022 Jul 15
Chest wall resection for breast cancer: 21st century Mayo clinic experience.
Diane M Durgan, Gabriel De La Cruz Ku, Mathew Thomas, Barbara A Pockaj, Sarah A McLaughlin, William J Casey, Aparna Vijayasekaran, Dennis Wigle, John C Cheville, Jenni...> ;Journal of Surgical Oncology. 2022 Nov 1
2 citations
Preoperative Type and Screen Before General Thoracic Surgery: A Nomogram to Reduce Unnecessary Tests.
Zaid M Abdelsattar, Vijay Joshi, Stephen Cassivi, Daryl Kor, K Robert Shen, Francis Nichols 3rd, Mark Allen, Shanda H Blackmon, Dennis Wigle> ;The Annals of Thoracic Surgery. 2023 Feb 1
Serial evaluation of segmental esophageal reconstruction using a polyurethane scaffold in a pig model.
Tiffany L Sarrafian, Jennifer L Brazzell, Matthew Barron, Johnathon Aho, Ellen Blanco, Chelsea Powell, Jed Johnson, Dennis A Wigle> ;Journal of Thoracic Disease. 2022 Jun 1
45 citations
Trastuzumab with trimodality treatment for oesophageal adenocarcinoma with HER2 overexpression (NRG Oncology/RTOG 1010): a multicentre, randomised, phase 3 trial.
Howard P Safran, Kathryn Winter, David H Ilson, Dennis Wigle, Thomas DiPetrillo, Michael G Haddock, Theodore S Hong, Lawrence P Leichman, Lakshmi Rajdev, Murray Resnic...> ;The Lancet. Oncology. 2022 Feb 1
1 citations
Massive intrathoracic solitary fibrous tumor of the right hemithorax.
Michael R. Boswell, Bradford B. Smith, Dennis A. Wigle, Phillip G. Rowse, Mark M. Smith> ;Annals of Cardiac Anaesthesia. 2021 Oct 1
4 citations
First-in-Human Segmental Esophageal Reconstruction Using a Bioengineered Mesenchymal Stromal Cell-Seeded Implant.
Johnathon M. Aho, Saverio La Francesca, Scott D. Olson, Fabio Triolo, Jeff Bouchard, Laura Mondano, Sumati Sundaram, Christina Roffidal, Charles S. Cox, Louis M. Wong ...> ;JTO Clinical and Research Reports. 2021 Sep 1
5 citations
Autologous blood patch pleurodesis for prolonged postoperative air leaks.
Irsa S. Hasan, Mark S. Allen, Stephen D. Cassivi, William S. Harmsen, Nandita Mahajan, Francis C. Nichols, Janani S. Reisenauer, Robert Shen, Dennis A. Wigle, Shanda H...> ;Journal of Thoracic Disease. 2021 Jun 1
A Comparison of Negative Pressure and Conventional Therapy in Infected Open Chest Wounds
Mathew Thomas, Ian A. Makey, Mauricia Buchanan, Michael G. Heckman, Launia J. White, Bettie J. Lechtenberg, Dennis A. Wigle, K. Robert Shen, Shanda H. Blackmon> ;Surgical Infections. 2021 May 26
13 citations
Induction versus no induction chemotherapy before neoadjuvant chemoradiotherapy and surgery in oesophageal adenocarcinoma: a multicentre randomised phase II trial (NCC...
Harry H. Yoon, Fang-Shu Ou, Gamini S. Soori, Qian Shi, Dennis A. Wigle, Robert P. Sticca, Robert C. Miller, James L. Leenstra, Patrick J. Peller, Brenda Ginos, Erica N...> ;European Journal of Cancer. 2021 Jun 1
9 citations
Integration of immunotherapy into adjuvant therapy for resected non-small-cell lung cancer: ALCHEMIST chemo-IO (ACCIO).
Jacob Sands, Sumithra J. Mandrekar, David Kozono, Geoffrey R. Oxnard, Shauna L. Hillman, Dennis A. Wigle, Ramaswamy Govindan, Jennifer Carlisle, Jhanelle E. Gray, Jose...> ;Immunotherapy. 2021 Apr 21
44 citations
Perioperative outcomes of pulmonary resection after neoadjuvant pembrolizumab in patients with non-small cell lung cancer.
Betty C. Tong, Lin Gu, Xiaofei Wang, Dennis A. Wigle, Joseph D. Phillips, David H. Harpole, Jacob A. Klapper, Thomas A. Sporn, Neal Ready, Thomas A. D'Amico> ;The Journal of Thoracic and Cardiovascular Surgery. 2021 Apr 9
8 citations
Ablative radiotherapy for ultracentral lung cancers: Dosimetric, geometric, and volumetric predictors of outcomes and toxicity.
William G. Breen, Elizabeth B. Jeans, Kimberly R. Gergelis, Yolanda I. Garces, Sean S. Park, Kenneth W. Merrell, Tobias Peikert, Aaron S. Mansfield, Dennis A. Wigle, W...> ;Radiotherapy and Oncology. 2021 Mar 10
2 citations
Heterogeneity of PD-L1 expression between invasive and lepidic components of lung adenocarcinomas.
Antonious Z. Hazim, Neil Majithia, Stephen J. Murphy, Dennis A. Wigle, Marie Christine Aubry, Aaron S. Mansfield> ;Cancer Immunology, Immunotherapy. 2021 Feb 18
11 citations
Minimally invasive thymectomy for myasthenia gravis favours left-sided approach and low severity class.
Sandra Blitz, Carson C Fuller, Jens C. Rückert, Feng Li, Asem F. Ghanim, Mark W. Onaitis, Inderpal S. Sarkaria, Dennis A. Wigle, Vijay Joshi, Scott I. Reznik, Adam J. ...> ;European Journal of Cardio-Thoracic Surgery. 2021 Feb 4
Join now to see all

Lectures

Mayo Clinic General Thoracic Surgery Symposium
Mayo School of Continuous Professional Development, Rochester, Minnesota - 5/3/2013

Press Mentions

Salvage Lung Resection After Immunotherapy in Lung Cancer Is Feasible and SafeMay 6th, 2023
Biostage Hires David Green as Chief Executive OfficerNovember 30th, 2021
Why You Can't Shake Pandemic Fatigue — and What to Do About ItAugust 10th, 2021
Join now to see all