DimitriosSpentzosMD

PubMed

• 5 citations
  Complete tumor necrosis after neoadjuvant chemotherapy defines good responders in patients with Ewing sarcoma.
  Santiago A Lozano-Calderón, Jose Ignacio Albergo, Olivier Q Groot, Nelson A Merchan, Jad M El Abiad, Vanessa Salinas, Luis Carlos Gomez Mier, Camilo Soto Montoya, Marc...> ;Cancer. 2023 Jan 1
• 10 citations
  Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma.
  Yun Wei, Qian Qin, Chuan Yan, Madeline N Hayes, Sara P Garcia, Haibin Xi, Daniel Do, Alexander H Jin, Tiffany C Eng, Karin M McCarthy, Abhinav Adhikari, Maristela L On...> ;Nature Cancer. 2022 Aug 1
• 15 citations
  EWSR1-ATF1 dependent 3D connectivity regulates oncogenic and differentiation programs in Clear Cell Sarcoma.
  Emely Möller, Viviane Praz, Sanalkumar Rajendran, Rui Dong, Alexandra Cauderay, Yu-Hang Xing, Lukuo Lee, Carlo Fusco, Liliane C Broye, Luisa Cironi, Sowmya Iyer, Shrut...> ;Nature Communications. 2022 Apr 27
• 8 citations
  Genome-wide DNA methylation patterns reveal clinically relevant predictive and prognostic subtypes in human osteosarcoma.
  Christopher E Lietz, Erik T Newman, Andrew D Kelly, David H Xiang, Ziying Zhang, Caroline A Luscko, Santiago A Lozano-Calderon, David H Ebb, Kevin A Raskin, Gregory M ...> ;Communications Biology. 2022 Mar 8
• 39 citations
  Myc is a prognostic biomarker and potential therapeutic target in osteosarcoma.
  Wenlong Feng, Dylan C. Dean, Francis J. Hornicek, Dimitrios Spentzos, Robert M. Hoffman, Huirong Shi, Zhenfeng Duan> ;Therapeutic Advances in Medical Oncology. 2020 May 10
• 7 citations
  MicroRNA-mRNA networks define translatable molecular outcome phenotypes in osteosarcoma
  Christopher E. Lietz, Cassandra Garbutt, William T. Barry, Vikram Deshpande, Yen-Lin Chen, Santiago A. Lozano-Calderon, Yaoyu E. Wang, Brian Lawney, David H. Ebb, Greg...> ;Scientific Reports. 2020 Mar 10
• 13 citations
  Clinical and Molecular Analysis of Pathologic Fracture-associated Osteosarcoma: MicroRNA profile Is Different and Correlates with Prognosis
  Santiago A. Lozano Calderón, Cassandra Garbutt, Jason Kim, Christopher E. Lietz, Yen-Lin Chen, Karen De Amorim Bernstein, Ivan Chebib, G. Petur Nielsen, Vikram Deshpan...> ;Clinical Orthopaedics and Related Research. 2019 Sep 1
• A Collision Tumor Involving a Primary Leiomyosarcoma of the Lower Extremity and a Metastatic Medullary Thyroid Carcinoma: A Case Report.
  Daniel C. Austin, Jim S. Wu, Dimitrios Spentzos, Jeff Goldsmith, Megan E. Anderson> ;JBJS Case Connector. 2017 Oct 1
• 36 citations
  Expression and Therapeutic Potential of SOX9 in Chordoma.
  Hua Chen, Cassandra Garbutt, Dimitrios Spentzos, Edwin Choy, Francis J. Hornicek, Zhenfeng Duan> ;Clinical Cancer Research. 2017 Jun 12
• 27 citations
  An imprinted non-coding genomic cluster at 14q32 defines clinically relevant molecular subtypes in osteosarcoma across multiple independent datasets.
  , , , , , , , , , , , , , , , , , > ;Journal of Hematology & Oncology. 2017 May 15
• 43 citations
  A network model for angiogenesis in ovarian cancer
  Kimberly Glass, John Quackenbush, Dimitrios Spentzos, Benjamin Haibe-Kains, Guo-Cheng Yuan> ;BMC Bioinformatics. 2015 Apr 11
• 30 citations
  MicroRNA-155 expression is independently predictive of outcome in chordoma
  Andrew Kelly, Dimitrios Spentzos, Edwin Choy, Xiaoqian Yang, Jacson Shen, Pei Yang, Henry J. Mankin, Francis J. Hornicek, Zhenfeng Duan> ;Oncotarget. 2015 Mar 17
• 35 citations
  Prognostic significance of miRNA-1 (miR-1) expression in patients with chordoma.
  Zhenfeng Duan, Jacson Shen, Xiaoqian Yang, Pei Yang, Eiji Osaka, Edwin Choy, Gregory M. Cote, David C. Harmon, Yu Zhang, G. Petur Nielsen, Dimitrios Spentzos, Henry J....> ;Journal of Orthopaedic Research. 2014 May 1
• 25 citations
  Next-generation sequencing and microarray-based interrogation of microRNAs from formalin-fixed, paraffin-embedded tissue: Preliminary assessment of cross-platform conc...
  Andrew Kelly, Katherine E. Hill, Mick Correll, Lan Hu, Yaoyu E. Wang, Renee Rubio, Shenghua Duan, John Quackenbush, Dimitrios Spentzos> ;Genomics. 2013 Jul 1
• 27 citations
  Stem cell-like gene expression in ovarian cancer predicts type II subtype and prognosis.
  Matthew Schwede, Dimitrios Spentzos, Stefan Bentink, Oliver Hofmann, Benjamin Haibe-Kains, David P. Harrington, John Quackenbush, Aedín C. Culhane> ;Plos One. 2013 Mar 11
• 72 citations
  MicroRNA paraffin-based studies in osteosarcoma reveal reproducible independent prognostic profiles at 14q32.
  Andrew Kelly, Benjamin Haibe-Kains, Katherine A. Janeway, Katherine E. Hill, Eleanor A. Howe, Jeff Goldsmith, Kyle C. Kurek, Antonio R. Perez-Atayde, Nancy Francoeur, ...> ;Genome Medicine. 2013 Jan 22
• 19 citations
  Identification and validation of gene expression models that predict clinical outcome in patients with early-stage laryngeal cancer
  Elena Fountzilas, Konstantinos Markou, Konstantinos Vlachtsis, Angelos Nikolaou, P. Arapantoni-Dadioti, E. Ntoula, G. Tassopoulos, Mattheos Bobos, Panagiotis A. Konsta...> ;Annals of Oncology. 2012 Aug 1
• 3 citations
  A microRNA activity map of human mesenchymal tumors: connections to oncogenic pathways; an integrative transcriptomic study
  Andrew Kelly, Antonio R. Perez-Atayde, Jeff Goldsmith, Panagiotis A. Konstantinopoulos, Nancy Francoeur, Mick Correll, Renee Rubio, Lan Hu, Mark C. Gebhardt, John Quac...> ;BMC Genomics. 2012 Jul 23
• 59 citations
  Metabolomic Profiling from Formalin-Fixed, Paraffin-Embedded Tumor Tissue Using Targeted LC/MS/MS: Application in Sarcoma
  Andrew Kelly, Susanne B. Breitkopf, Min Yuan, Jeff Goldsmith, Dimitrios Spentzos, John M. Asara> ;Plos One. 2011 Oct 3
• 210 citations
  Keap1 mutations and Nrf2 pathway activation in epithelial ovarian cancer.
  Panagiotis A. Konstantinopoulos, Dimitrios Spentzos, Elena Fountzilas, Nancy Francoeur, Srisowmya Sanisetty, Alexandros P. Grammatikos, Jonathan L. Hecht, Stephen A. C...> ;Cancer Research. 2011 Aug 1
• Prediction of clinical outcome in patients with primary laryngeal carcinoma using gene expression profiling.
  Fountzilas E, Angouridakis N, Karasmanis I, Wirtz RM, Eleftheraki AG, Veltrup E, Markou K, Nikolaou A, Konstantinopoulos P, Kotoula V, Spentzos D, Fountzilas G> ;J. Clin. Oncol.. 2011-05-20
• 28 citations
  Integrated analysis of multiple microarray datasets identifies a reproducible survival predictor in ovarian cancer.
  Panagiotis A. Konstantinopoulos, Stephen A. Cannistra, Helen Fountzilas, Aedín C. Culhane, Kamana Pillay, Bo R. Rueda, Daniel W. Cramer, Michael V. Seiden, Michael J. ...> ;Plos One. 2011 Mar 29
• 360 citations
  Gene expression profile of BRCAness that correlates with responsiveness to chemotherapy and with outcome in patients with epithelial ovarian cancer.
  Panagiotis A. Konstantinopoulos, Dimitrios Spentzos, Beth Y. Karlan, Toshiyasu Taniguchi, Elena Fountzilas, Nancy Francoeur, Douglas A. Levine, Stephen A. Cannistra> ;Journal of Clinical Oncology. 2010 Aug 1
• 15 citations
  Analysis of multiple sarcoma expression datasets: implications for classification, oncogenic pathway activation and chemotherapy resistance.
  Panagiotis A. Konstantinopoulos, Elena Fountzilas, Jeff Goldsmith, Manoj Bhasin, Kamana Pillay, Nancy Francoeur, Towia A. Libermann, Mark C. Gebhardt, Dimitrios Spentzos> ;Plos One. 2010 Apr 1
• 23 citations
  Generation of tumor-specific T lymphocytes using dendritic cell/tumor fusions and anti-CD3/CD28.
  Jacalyn Rosenblatt, Zekui Wu, Baldev Vasir, Corrine Zarwan, Richard Stone, Heidi Mills, Thea M. Friedman, Panagiotis A. Konstantinopoulos, Dimitrios Spentzos, Musie Gh...> ;Journal of Immunotherapy. 2010 Feb 1
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