MarcelaValderamaMausMDPhD

PubMed

• Current and emerging pharmacotherapies for cytokine release syndrome, neurotoxicity, and hemophagocytic lymphohistiocytosis-like syndrome due to CAR T cell therapy.
  Zandra E Walton, Matthew J Frigault, Marcela V Maus> ;Expert Opinion on Pharmacotherapy. 2024 Apr 10
• National Survey of FACT-Accredited Cell Processing Facilities: Assessing Preparedness for Local Manufacturing of Immune Effector Cells.
  Magdi Elsallab, Florence Bourgeois, Marcela V Maus> ;Transplantation and Cellular Therapy. 2024 Mar 16
• Second Primary Malignancies After Commercial CAR T Cell Therapy: Analysis of FDA Adverse Events Reporting System (FAERS).
  Magdi Elsallab, Moataz Ellithi, Matthew A Lunning, Christopher D'Angelo, Jihyun Ma, Miguel-Angel Perales, Matthew J Frigault, Marcela V Maus> ;Blood. 2024 Mar 14
• Intraventricular CARv3-TEAM-E T Cells in Recurrent Glioblastoma.
  Bryan D Choi, Elizabeth R Gerstner, Matthew J Frigault, Mark B Leick, Christopher W Mount, Leonora Balaj, Sarah Nikiforow, Bob S Carter, William T Curry, Kathleen Gall...> ;The New England Journal of Medicine. 2024 Apr 11
• Optimization of a flow cytometry test for routine monitoring of B cell maturation antigen targeted CAR in peripheral blood.
  Won-Ho Lee, Charlotte E Graham, Hadley R Wiggin, Hannah K Nolan, Kiana J Graham, Felix Korell, Mark B Leick, Alexis L Barselau, Estelle Emmanuel-Alejandro, Michael A T...> ;Cytometry. Part B, Clinical Cytometry. 2024 Feb 28
• Mesothelin CAR T-cells secreting anti-FAP/anti-CD3 molecules efficiently target pancreatic adenocarcinoma and its stroma.
  Wehrli, M., Guinn, S., Birocchi, F., Kuo, A., Sun, Y., Larson, R., Almazan, A., Scarfò, I., Bouffard, A., Bailey, S., Anekal, P., Montero Lopis, P., Nieman, L., Song, ...> ;Clinical Cancer Research. 2024 Feb 23
• Targeting solid tumor antigens with chimeric receptors: cancer biology meets synthetic immunology.
  Gabriele J Kembuan, Joanna Y Kim, Marcela V Maus, Max Jan> ;Trends in Cancer. 2024 Apr 1
• Understanding Mechanisms of Response to CAR T-cell Therapy through Single-Cell Sequencing: Insights and Challenges.
  Haradhvala, N., Maus, M.> ;Blood Cancer Discovery. 2024 Mar 1
• 4 citations
  Unanswered questions following reports of secondary malignancies after CAR-T cell therapy.
  Levine, B., Pasquini, M., Connolly, J., Porter, D., Gustafson, M., Boelens, J., Horwitz, E., Grupp, S., Maus, M., Locke, F., Ciceri, F., Ruggeri, A., Snowden, J., Hesl...> ;Nature Medicine. 2024 Feb 1
• Chemical genetic control of cytokine signaling in CAR-T cells using lenalidomide-controlled membrane-bound degradable IL-7.
  Kann, M., Schneider, E., Almazan, A., Lane, I., Bouffard, A., Supper, V., Takei, H., Tepper, A., Larson, R., Jan, M., Leick, M., Ebert, B., Maus, M.> ;Leukemia. 2024 Mar 1
• Bispecific CD33/CD123 targeted chimeric antigen receptor T cells for the treatment of acute myeloid leukemia.
  Boucher, J., Shrestha, B., Vishwasrao, P., Cervantes, E., Ghafoor, T., Reid, K., Spitler, K., Yu, B., Guevara-Patino, J., Leick, M., Betts, B., Maus, M., Davila, M.> ;Molecular Therapy Oncolytics. 2023 Dec 19
• Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening.
  Ramos, A., Koch, C., Liu-Lupo, Y., Hellinger, R., Kyung, T., Abbott, K., Fröse, J., Goulet, D., Gordon, K., Eidell, K., Leclerc, P., Whittaker, C., Larson, R., Muscato...> ;Nature Communications. 2023 Dec 5
• Anti-TACI single and dual-targeting CAR T cells overcome BCMA antigen loss in multiple myeloma.
  Rebecca C Larson, Michael C Kann, Charlotte Graham, Christopher W Mount, Ana P Castano, Won-Ho Lee, Amanda A Bouffard, Hana N Takei, Antonio J Almazan, Irene Scarfó, T...> ;Nature Communications. 2023 Nov 18
• 2 citations
  Genetic retargeting of E3 ligases to enhance CAR T cell therapy.
  Isabel C Lane, Gabriele Kembuan, Jeannie Carreiro, Michael C Kann, William Lin, Amanda A Bouffard, Johannes Kreuzer, Robert Morris, Emily M Schneider, Joanna Y Kim, Ch...> ;Cell Chemical Biology. 2024 Feb 15
• 6 citations
  Latent human herpesvirus 6 is reactivated in CAR T cells.
  Caleb A Lareau, Yajie Yin, Katie Maurer, Katalin D Sandor, Bence Daniel, Garima Yagnik, José Peña, Jeremy Chase Crawford, Anne M Spanjaart, Jacob C Gutierrez, Nicholas...> ;Nature. 2023 Nov 1
• 7 citations
  Mechanisms of resistance to chimeric antigen receptor-T cells in haematological malignancies.
  Marco Ruella, Felix Korell, Patrizia Porazzi, Marcela V Maus> ;Nature Reviews. Drug Discovery. 2023 Dec 1
• 2 citations
  Expanding access to CAR T cell therapies through local manufacturing.
  Magdi Elsallab, Marcela V Maus> ;Nature Biotechnology. 2023 Dec 1
• 4 citations
  Synthetic manipulation of the cancer-immunity cycle: CAR-T cell therapy.
  Nathan Singh, Marcela V Maus> ;Immunity. 2023 Oct 10
• 3 citations
  "Hurdles race for CAR T-cell therapy in digestive tract cancer".
  Marie-Noelle Kronig, Marc Wehrli, Diego Salas-Benito, Marcela V Maus> ;Immunological Reviews. 2023 Nov 1
• 8 citations
  Idecabtagene vicleucel for relapsed and refractory multiple myeloma: post hoc 18-month follow-up of a phase 1 trial.
  Yi Lin, Noopur S Raje, Jesús G Berdeja, David S Siegel, Sundar Jagannath, Deepu Madduri, Michaela Liedtke, Jacalyn Rosenblatt, Marcela V Maus, Monica Massaro, Fabio Pe...> ;Nature Medicine. 2023 Sep 1
• 4 citations
  Chemotherapy-induced reversal of ciltacabtagene autoleucel-associated movement and neurocognitive toxicity.
  Charlotte E Graham, Won-Ho Lee, Hadley R Wiggin, Valentina M Supper, Mark B Leick, Filippo Birocchi, Andrew J Yee, Angelina Petrichenko, John Everett, Frederic D Bushm...> ;Blood. 2023 Oct 5
• A robust quality infrastructure is key to safe and effective delivery of immune effector cells: how FACT-finding can help.
  Kevin J Curran, Sarah Nikiforow, Carlos Bachier, Yen-Michael Hsu, Marcela V Maus, Basem William, Kara Wacker, Phyllis Warkentin, Helen E Heslop, David Maloney, Philip ...> ;Blood Advances. 2024 Feb 27
• 29 citations
  Immune Effector Cell-Associated Hemophagocytic Lymphohistiocytosis-Like Syndrome.
  Ombrello, A. K., Ombrello, A. K., Melissa R Hines, Tristan E Knight, Kevin O McNerney, Mark B Leick, Tania Jain, Sairah Ahmed, Matthew J Frigault, Joshua A Hill, Micha...> ;Transplantation and Cellular Therapy. 2023 Jul 1
• 1 citations
  Signatures of dysfunctional CAR T cells.
  Marcela V Maus> ;Blood. 2023 Jun 29
• 1 citations
  Quantifying requirements for mitochondrial apoptosis in CAR T killing of cancer cells.
  Alexandra L Pourzia, Michael L Olson, Stefanie R Bailey, Angela C Boroughs, Aditi Aryal, Jeremy Ryan, Marcela V Maus, Anthony Letai> ;Cell Death & Disease. 2023 Apr 13
• Join now to see all

Journal Articles

• Making CAR T Cells a Solid Option for Solid Tumors  
  Marcela Maus, MD, Frontiers in Neurology
• Immunotherapy for Glioblastoma: Adoptive T-cell Strategies  
  Marcela V Maus, Carl H June, Clinical Cancer Research

Abstracts/Posters

• Use of CD70 Targeted Chimeric Antigen Receptor (CAR) T Cells for the Treatment of Acute Myeloid Leukemia (AML)
  Marcela V. Maus, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Exploiting the Zinc Finger Degrome Targeted By Lenalidomide to Engineer Reversible Off-Switch Degradable Chimeric Antigen Receptors
  Marcela V Maus, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019

Lectures

• Hit the Ground Running: What You Need to Know About CAR T-Cell Therapy 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
• Engineering an Optimized Trimeric APRIL-Based CAR to Broaden Targetability of Multiple Myeloma 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Overcoming a Critical Obstacle Towards Effective and Safe CAR T-Cell Therapeutics 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Axicabtagene Ciloleucel in the Real World: Outcomes and Predictors of Response, Resistance and Toxicity 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Join now to see all