Ephraim P Hochberg MD

Hematologic Oncology

Assistant Professor in Medicine, Harvard Medical School. Executive Vice Chair, Hematology Oncology, Mass General Brigham Cancer Institute Ian K. and Isabelle P. Loring Endowed Chair in Lymphoma

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55 Fruit StYaw 7BBoston, MA 02114
Phone+1 617-724-4000
Fax+1 617-724-6801

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Summary

Ephraim Hochberg, MD, is an oncologist specializing in hematologic oncology based in Boston, MA. He completed his fellowship in Hematology and Medical Oncology at Mass General Brigham/Brigham and Women's Hospital/Massachusetts General Hospital/Dana-Farber Cancer Institute in 2002. Dr. Hochberg is experienced in treating conditions such as Hodgkin lymphoma, non-Hodgkin lymphoma, and chronic lymphocytic leukemia. He has authored more than 100 publications on topics related to lymphoma and has been involved in clinical trials for treatments in mantle cell lymphoma and diffuse large B-cell non-Hodgkin's lymphoma. Among his recognitions, Dr. Hochberg has been named among America's Top Doctors from 2011 to 2022.

Education & Training

Mass General Brigham/Brigham and Women's Hospital/Massachusetts General Hospital/Dana-Farber Cancer InstituteFellowship, Hematology and Medical Oncology, 1999 - 2002
Mass General Brigham/Brigham and Women's HospitalInternship, Internal Medicine, 1996 - 1997
Case Western Reserve University School of MedicineClass of 1996

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Certifications & Licensure

MA State Medical License 1998 - 2028
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2011-2022
CMS Meaningful Use Stage 1 Certification Partners Longitudinal Medical Record, Partners Healthcare System, 2012, 2014, 2016-2017
CMS Meaningful Use Stage 2 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2012, 2014, 2016-2017

Clinical Trials

CHOP-Rituximab Augmented With GM-CSF in Patients With Previously Untreated Diffuse Large B Cell Non-Hodgkin's Lymphoma
TERMINATED
PHASE2
Rituximab/Bendamustine + Rituximab/Cytarabine for Mantle Cell Lymphoma Start of enrollment: 2012 Aug 16
ACTIVE_NOT_RECRUITING
PHASE2

Publications & Presentations

PubMed

Zanubrutinib, obinutuzumab, and venetoclax in CLL: long-term follow up, MRD kinetics, retreatment, T-cell profiling, and PKs.
Jacob D Soumerai, Meghan C Thompson, Ahmet Dogan, Venkatraman Seshan, Kelsey L Flaherty
Blood Advances. 2026-11-10
9 citations
Hodgkin Lymphoma, Version 1.2026, NCCN Clinical Practice Guidelines In Oncology.
Ranjana H Advani, Christopher R Kelsey, Philippe Armand, Celeste M Bello, Cecil M Benitez
Journal of the National Comprehensive Cancer Network. 2026-02-01
1 citations
A retrospective study of treatment and outcomes in synchronous systemic and central nervous system large B-cell lymphoma.
J Erika Haydu, Robert A Redd, Matthew M Lei, Ephraim P Hochberg, Jeffrey A Barnes
Blood Advances. 2026-01-27

Journal Articles

Pilot Randomized Trial of an Electronic Symptom Monitoring Intervention for Hospitalized Patients with Cancer
E P Hochberg, D P Ryan, J S Temel, V A Jackson, J A Greer, Annals of Oncology

Abstracts/Posters

Ibrutinib Maintenance (I-M) Following Frontline Intensive Induction in Mantle Cell Lymphoma (MCL): Interim Safety, Response and Sequential MRD Evaluation
Ephraim Hochberg, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019

Press Mentions

$1 Million Gift to Mass General Cancer Center Will Support Promising Research Conducted by Pioneering Physician-ScientistsOctober 21st, 2024
Case 31-2020: A 48-Year-Old Man with Lymphoma and Abdominal PainOctober 8th, 2020
A New Cancer Care Dilemma: Patients Want Immunotherapy Even When Evidence Is LackingJune 4th, 2018

Professional Memberships

American Society of Clinical Oncology - ASCO
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