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Leonard Zon, MD, Oncology, Boston, MA, Boston Children's Hospital

LeonardIZonMD

Oncology • Boston, MA

Hematologic Oncology

Professor, Pediatrics, Children's Hospital, Harvard Medical School

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Education & Training

  • Brigham and Women's Hospital/Massachusetts General Hospital/Dana-Farber Cancer Institute
    Brigham and Women's Hospital/Massachusetts General Hospital/Dana-Farber Cancer InstituteFellowship, Hematology and Medical Oncology, 1986 - 1988
  • Beth Israel Deaconess Medical Center
    Beth Israel Deaconess Medical CenterResidency, Internal Medicine, 1983 - 1986
  • Sidney Kimmel Medical College at Thomas Jefferson University
    Sidney Kimmel Medical College at Thomas Jefferson UniversityClass of 1983

Certifications & Licensure

  • MA State Medical License
    MA State Medical License 1986 - 2025
  • American Board of Internal Medicine Internal Medicine
  • American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

  • Elected Member Institute of Medicine, 2005
  • Elected Member The American Society for Clinical Investigation, 1996
  • Investigator Howard Hughes Medical Institute
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Publications & Presentations

PubMed

Journal Articles

  • Human Tumor Genomics and Zebrafish Modeling Identify SPRED1 Loss as a Driver of Mucosal Melanoma  
    Hong Wu, Richard C Jordan, Boris C Bastian, Leonard I Zon, Iwei Yeh, Science Magazine
  • Protection from UV Light Is an Evolutionarily Conserved Feature of the Haematopoietic Niche  
    David E Fisher, John M Gansner, Leonard I Zon, Nature

Abstracts/Posters

  • Ing4 Regulates Stress Hematopoiesis and Represses Self-Renewal in Multipotent Progenitor Cells
    Leonard I. Zon, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
  • Transcription Factor Induction of Ectopic Vascular Blood Stem Cell Niches In Vivo
    Leonard I. Zon, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
  • Transcriptional Regulation of Coenzyme Q Biosynthesis By TIF1_ Drives Erythropoiesis
    Leonard I. Zon, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
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Lectures

  • Transcriptional Signaling Centers Govern Human Erythropoiesis and Harbor Genetic Variations of Red Blood Cell Traits 
    2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
  • Friday Scientific Workshop on Myeloid Development: Transcription Factors 
    60th American Society of Hematology Annual Meeting - 11/30/2018

Press Mentions

  • Could We Make Blood Anywhere in the Body?
    Could We Make Blood Anywhere in the Body?May 10th, 2023
  • A New Cancer Mechanism: Failed Cellular Housekeeping
    A New Cancer Mechanism: Failed Cellular HousekeepingMay 8th, 2023
  • Hoxa9/meis1-transgenic Zebrafish Develops Acute Myeloid Leukaemia-like Disease with Rapid Onset and High Penetrance
    Hoxa9/meis1-transgenic Zebrafish Develops Acute Myeloid Leukaemia-like Disease with Rapid Onset and High PenetranceOctober 1st, 2022
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Grant Support

  • A Comparative Approach To Globin Regulation/ThalassemiaNational Institute Of Diabetes And Digestive And Kidney Diseases2003–2012
  • Cancer Biology In The ZebrafishNational Cancer Institute2003–2012
  • Customized Stem Cells For Clinical Application In Blood DisordersNational Institute Of Diabetes And Digestive And Kidney Diseases2011
  • Control Of Erythroid Differentiation By Transcription ElongationNational Heart, Lung, And Blood Institute2011
  • Human Pluripotent Stem Cell And Progenitor Models Of Cardiac And Blood DiseasesNational Heart, Lung, And Blood Institute2009–2011
  • Embryonic HematopoiesisNational Heart, Lung, And Blood Institute1992–2011
  • Mount Desert Island Stem Cell SymposiumNational Institute Of General Medical Sciences2010
  • Role Of Tif1y In ErythropoiesisNational Heart, Lung, And Blood Institute2006–2010
  • Characterizing The Zebrafish GenomeNational Institute Of Diabetes And Digestive And Kidney Diseases2003–2010
  • Induced Pluripotent Cells For Blood DiseasesNational Heart, Lung, And Blood Institute2009
  • Core--ZebrafishNational Institute Of Diabetes And Digestive And Kidney Diseases1999–2009
  • Mount Desert Island Stem Cell SymposiumNational Institute Of Diabetes And Digestive And Kidney Diseases2007–2008
  • Fetal Globin SilencingNational Heart, Lung, And Blood Institute2003–2006
  • International Society For Stem Cell Research MeetingNational Institute Of Diabetes And Digestive And Kidney Diseases2002–2006
  • Red Cell Gordon ConferenceNational Institute Of Diabetes And Digestive And Kidney Diseases2005
  • Comparative Approach To The Hematopoietic Stem CellNational Institute Of Diabetes And Digestive And Kidney Diseases2002–2004
  • Ferroportin 1 In Vertebrate Iron UtilizationNational Heart, Lung, And Blood Institute2001–2002
  • Core--Functional Genomics And BioinformaticsNational Institute Of Diabetes And Digestive And Kidney Diseases1999–2002
  • Comparative Approach To Globin Regulation/ThalassemiaNational Institute Of Diabetes And Digestive And Kidney Diseases1998–2002
  • Characterizing The Zebrafish GenomeNational Institute Of Diabetes And Digestive And Kidney Diseases1998–2002
  • Signal Transduction In Erythroid CellsNational Heart, Lung, And Blood Institute1996–2000
  • Induction Of The Hematopoiesis Stem Cell During Zebrafish EmbryogenesisNational Institute Of Diabetes And Digestive And Kidney Diseases1996–1998
  • Core--ZebrafishNational Institute Of Diabetes And Digestive And Kidney Diseases1996–1998
  • Current Advances In Defining The Zebrafish GenomeNational Institute Of Diabetes And Digestive And Kidney Diseases1997
  • Erythropoietin Ligand-Receptor InteractionNational Heart, Lung, And Blood Institute1989–1992

Hospital Affiliations

Dr. Leonard Zon, Dr. Leonard Zon, MD, Dr. L Zon, Dr. Leonard I Zon