Dmitriy Zamarin MD PhD

Oncology•New York, NY

Gynecologic Cancer

Section Head, Gynecologic Medical Oncology

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Icahn School of Medicine at Mount Sinai1470 Madison AveNew York, NY 10029

Summary

I am a medical oncologist specializing in the care of women with gynecologic cancers, including cervical, ovarian, and endometrial cancers. My clinical and laboratory research is focused on the development of novel ways to use the immune system to treat cancer. In addition, I have a special interest in genetically engineered oncolytic viruses, an emerging class of immune therapeutic drugs. By manipulating the oncolytic viruses and the immune system, I’m exploring different ways to enhance the immune recognition of tumors and to develop novel treatment strategies for gynecologic cancers.

Education & Training

Memorial Sloan Kettering Cancer CenterFellowship, Hematology and Medical Oncology, 2010 - 2014
Icahn School of Medicine at Mount Sinai/Mount Sinai HospitalResidency, Internal Medicine, 2008 - 2010
Icahn School of Medicine at Mount SinaiClass of 2008

Certifications & Licensure

FL State Medical License 2021 - Present
NY State Medical License 2009 - 2027
NJ State Medical License 2019 - 2025
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

Liz Tilberis Early Career Award Ovarian Cancer Research Alliance
GOG Foundation Scholar Investigator Award GOG Foundation, 2019
MSKCC Academic Excellence Recognition Award Memorial Sloan Kettering Cancer Center, 2018
Judith Liebenthal Robinson Ovarian Cancer Foundation Award Foundation for Women's Cancers, 2015
Bladder Cancer Awareness Network Young Investigator Award Bladder Cancer Awareness Network, 2014
Conquer Cancer Foundation ASCO Young Investigator Award Conquer Cancer Foundation, 2013
Damon Runyon Foundation Fellowship Award Damon Runyon Foundation, 2012
Celgene Future Leaders in Hematology Award Celgene, 2012
American Society of Hematology Abstract Achievement Award American Society of Hematology, 2011
Department of Medicine Award for excellence in research Mount Sinai School of Medicine, 2010
Harold Elster Memorial Prize for Highest Academic Standing Mount Sinai School of Medicine, 2008
Barry Coller Award for Excellence in Clinical Medicine Mount Sinai School of Medicine, 2008
Alpha Omega Alpha Mount Sinai School of Medicine, 2008
Graduate Student Conference Travel Awards Mount Sinai School of Medicine, 2004-2008
Award for Best Doctoral Dissertation Mount Sinai School of Medicine, 2006
American Society for Virology Travel Award American Society for Virology, 2005
Teaching Assistant Award Mount Sinai School of Medicine, 2005
Academic Excellence Award Mount Sinai School of Medicine, 2003
Student Service Award Mount Sinai School of Medicine, 2002
Summa Cum Laude Manhattan College, 2000
Phi Beta Kappa Manhattan College, 1999
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Clinical Trials

A Study of Carboplatin and Paclitaxel Chemotherapy With Nivolumab With or Without Ipilimumab in Patients With Ovarian Cancer Start of enrollment: 2017 Aug 04
ACTIVE_NOT_RECRUITING
PHASE1
Study of Pembrolizumab Following Surgery in Patients With Microsatellite Instability High (MSI-H) Solid Tumors Start of enrollment: 2019 Feb 20
ACTIVE_NOT_RECRUITING
EARLY_PHASE1
Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial Cancer Start of enrollment: 2020 Apr 09
ACTIVE_NOT_RECRUITING
PHASE3
ZW25 in Women With Endometrial Cancers Start of enrollment: 2020 Aug 12
COMPLETED
PHASE2
A Study of MEDI9253 in Combination With Durvalumab in Select Solid Tumors Start of enrollment: 2020 Dec 02
TERMINATED
PHASE1
Radiation and TSR-042 (Dostarlimab) in People With Endometrial Cancer After They Receive Surgery Start of enrollment: 2021 Apr 02
RECRUITING
PHASE2
STK-012 Monotherapy and in Combination Therapy in Patients With Solid Tumors Start of enrollment: 2022 Jan 25
RECRUITING
PHASE1
Roles: Contact
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Publications & Presentations

PubMed

Tracking clonal evolution during treatment in ovarian cancer using cell-free DNA.
Marc J Williams, Ignacio Vázquez-García, Grittney Tam, Michelle Wu, Nancy Varice
Nature. 2025-10-01
2 citations
A working group report from the 2024 National Cancer Institute / Gynecologic Cancer Steering Committee endometrial cancer clinical trials planning meeting: refining th...
Casey M Cosgrove, Dmitriy Zamarin, Jose R Conejo-Garcia, Kari E Hacker, Roberto Vargas
Journal of the National Cancer Institute. 2025-09-01
Early-stage uterine papillary serous carcinoma: Clinical outcomes in patients treated with adjuvant chemotherapy and vaginal brachytherapy.
Daniel R Cherry, Vishal Gupta, Julie R Bloom, Kristin Hsieh, Valentin Kolev
Gynecologic Oncology. 2025-08-22

Journal Articles

A Phase 1 Dose-Escalation Study of Intraperitoneal Cisplatin, intravenous/intraperitoneal Paclitaxel, Bevacizumab, and Olaparib for Newly Diagnosed Ovarian Cancer
Karen A Cadoo, Roisin E O'Cearbhaill, Dmitriy Zamarin, Paul J Sabbatini, William P Tew, Carol Aghajanian, Jason A Konner, Gynecologic Oncology

Press Mentions

MSK Research Highlights, December 18, 2024December 17th, 2024
Mount Sinai Launches Center of Excellence to Enhance Treatment and Care for Patients with Gynecologic CancerSeptember 16th, 2024
Key Advances and Advocacy Are Themes at SGO Annual MeetingMarch 21st, 2023
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Grant Support

POTENTIATION OF ANTI-TUMOR IMMUNITY BY ONCOLYTIC VIRUS IN SITU VACCINATIONICAHN SCHOOL OF MEDICINE AT MOUNT SINAI2023–2028
Immunogenomic predictors of outcomes in patients with locally advanced cervical cancer treated with immunotherapy and chemoradiationICAHN SCHOOL OF MEDICINE AT MOUNT SINAI2023–2026
Profiling co‑evolution of ovarian cancer and its immune microenvironmentOvarian Cancer Research Alliance2020–2022

Committees

Chair, Translational Science, NRG Oncology Cervical Cancer Committee 2018 - Present
Member, NRG Oncology Developmental Therapeutics Committee 2018 - Present
Member, Institutional Biosafety Committee 2016 - Present
Member, Protocol Development Committee 2015 - Present
Member, Pharmacy and Therapeutics Committee, MSKCC 2014 - Present