DonaldMaxwellMD

PubMed

• 3 citations
  Radiolabelled soman binding to sera from Rats, Guinea Pigs and Monkeys.
  David E. Lenz, Douglas M. Cerasoli, Donald M. Maxwell> ;Toxicology Letters. 2018 Feb 1
• 15 citations
  Design, synthesis, and characterization of novel, nonquaternary reactivators of GF-inhibited human acetylcholinesterase
  Stanton F. McHardy, Jonathan Bohmann, Michael R. Corbett, Bismarck Campos, Michael W. Tidwell, Paul M. Thompson, Christopher J. Bemben, Tony A. Menchaca, Tony E. Reeve...> ;Bioorganic & Medicinal Chemistry Letters. 2014 Apr 1
• 11 citations
  A common mechanism for resistance to oxime reactivation of acetylcholinesterase inhibited by organophosphorus compounds.
  Donald M. Maxwell, Karen M. Brecht, Richard E. Sweeney> ;Chemico-Biological Interactions. 2013 Mar 25
• 30 citations
  Comparison of oxime reactivation and aging of nerve agent-inhibited monkey and human acetylcholinesterases.
  Chunyuan Luo, Min Tong, Donald M. Maxwell, Ashima Saxena> ;Chemico-Biological Interactions. 2008 Sep 25
• 45 citations
  A structure-activity analysis of the variation in oxime efficacy against nerve agents.
  Donald M. Maxwell, Irwin Koplovitz, Franz Worek, Richard E. Sweeney> ;Toxicology and Applied Pharmacology. 2008 Sep 1
• 61 citations
  An In Vitro Comparative Study on the Reactivation of Nerve Agent-Inhibited Guinea Pig and Human Acetylcholinesterases by Oximes
  Chunyuan Luo, Min Tong, Nageswararao Chilukuri, Karen Brecht, Donald M Maxwell, Ashima Saxena> ;Biochemistry. 2007 Sep 27
• 47 citations
  Crystal structures of human carboxylesterase 1 in covalent complexes with the chemical warfare agents soman and tabun.
  Christopher D. Fleming, Carol C. Edwards, Stephen D. Kirby, Donald M. Maxwell, Philip M. Potter, Douglas M. Cerasoli, Matthew R. Redinbo> ;Biochemistry. 2007 May 1
• 22 citations
  Effect of octanol:water partition coefficients of organophosphorus compounds on biodistribution and percutaneous toxicity.
  Steven E. Czerwinski, John P. Skvorak, Donald M. Maxwell, David E. Lenz, Steven I. Baskin> ;Journal of Biochemical and Molecular Toxicology. 2006 Oct 1
• 66 citations
  Acetylcholinesterase inhibition: does it explain the toxicity of organophosphorus compounds?
  Donald M. Maxwell, Karen M. Brecht, Irwin Koplovitz, Richard E. Sweeney> ;Archives of Toxicology. 2006 Jun 13
• 14 citations
  A physiologically based pharmacokinetic (PB/PK) model for multiple exposure routes of soman in multiple species
  Richard E. Sweeney, Jan P. Langenberg, Donald M. Maxwell> ;Archives of Toxicology. 2006 May 23
• 93 citations
  Protection against soman or VX poisoning by human butyrylcholinesterase in guinea pigs and cynomolgus monkeys.
  David E. Lenz, Donald M. Maxwell, Irwin Koplovitz, Connie R. Clark, Benjamin R. Capacio, Douglas M. Cerasoli, James M. Federko, Chunyuan Luo, Ashima Saxena, B. P. Doct...> ;Chemico-Biological Interactions. 2005 Dec 15
• 21 citations
  Two possible orientations of the HI-6 molecule in the reactivation of organophosphate-inhibited acetylcholinesterase
  Chunyuan Luo, Haim Leader, Zoran Radić, Donald M. Maxwell, Palmer Taylor, Bhupendra P. Doctor, Ashima Saxena> ;Biochemical Pharmacology. 2003 Aug 1
• 14 citations
  A theoretical expression for the protection associated with stoichiometric and catalytic scavengers in a single compartment model of organophosphorus poisoning
  Richard E. Sweeney, Donald M. Maxwell> ;Mathematical Biosciences. 2003 Feb 1
• 61 citations
  Carboxylesterase: specificity and spontaneous reactivation of an endogenous scavenger for organophosphorus compounds
  Donald M. Maxwell, Karen M. Brecht> ;Journal of Applied Toxicology. 2001 Dec 1
• 14 citations
  A theoretical model of the competition between hydrolase and carboxylesterase in protection against organophosphorus poisoning.
  Richard E. Sweeney, Donald M. Maxwell> ;Mathematical Biosciences. 1999 Aug 1
• 21 citations
  Organophosphate skin decontamination using immobilized enzymes
  Richard K. Gordon, Shawn R. Feaster, Alan J. Russell, Keith E. LeJeune, Donald M. Maxwell, David E. Lenz, Michelle Ross, Bhupendra P. Doctor> ;Chemico-Biological Interactions. 1999 May 14
• 11 citations
  Improvements in scavenger protection against organophosphorus agents by modification of cholinesterases.
  Donald M. Maxwell, Ashima Saxena, Richard K. Gordon, Bhupendra P. Doctor> ;Chemico-Biological Interactions. 1999 May 14
• 22 citations
  The pH dependence of dealkylation in soman-inhibited cholinesterases and their mutants: Further evidence for a push-pull mechanism
  Ashima Saxena, Carol Viragh, D. S. Frazier, Ildiko M. Kovach, Donald M. Maxwell, Oksana Lockridge, Bhupendra P. Doctor> ;Biochemistry. 1998 Oct 27
• 29 citations
  Mutant acetylcholinesterases as potential detoxification agents for organophosphate poisoning
  Ashima Saxena, Donald M. Maxwell, Daniel M. Quinn, Zoran Radić, Palmer Taylor, Bhupendra P. Doctor> ;Biochemical Pharmacology. 1997 Jul 15
• 23 citations
  Development of a physiologically based model for the toxicokinetics of C(+/-)P(+/-)-soman in the atropinized guinea pig.
  Jan P. Langenberg, C. Van Dijk, Richard E. Sweeney, Donald M. Maxwell, L.P.A. de Jong, Hendrik P. Benschop> ;Archives of Toxicology. 1997 Jan 1
• 3 citations
  Temperature Effects in Cyanolysis Using Elemental Sulfur
  Claire N. Lieske, Connie R. Clark, Lamar Dean Zoeffel, Robert L. von Tersch, John R. Lowe, C. Dahlem Smith, Clarence A. Broomfield, Steven I. Baskin, Donald M. Maxwell> ;Journal of Applied Toxicology. 1996 Mar 1
• 13 citations
  Oxime-induced reactivation of carboxylesterase inhibited by organophosphorus compounds.
  Donald M. Maxwell, Claire N. Lieske, Karen M. Brecht> ;Chemical Research in Toxicology. 1994 May 1
• 19 citations
  Behavioral decrements persist in rhesus monkeys trained on a serial probe recognition task despite protection against soman lethality by butyrylcholinesterase
  Carl A. Castro, V.C. Gresham, A.V. Finger, Donald M. Maxwell, Richard P. Solana, David E. Lenz, Clarence A. Broomfield> ;Neurotoxicology and Teratology. 1994 Mar 1
• 25 citations
  Amplification of the effectiveness of acetylcholinesterase for detoxification of organophosphorus compounds by bis-quaternary oximes.
  German R. Caranto, Kirk H. Waibel, Jacob M. Asher, Roberta W. Larrison, Karen M. Brecht, Michael B. Schutz, Lily Raveh, Yacov Ashani, Alan D. Wolfe, Donald M. Maxwell,...> ;Biochemical Pharmacology. 1994 Jan 20
• 4 citations
  Contribution of direct actions of the oxime HI-6 in reversing soman-induced muscle weakness in the rat diaphragm☆
  Michael Adler, Donald M. Maxwell, Margaret G. Filbert, Sharad S. Deshpande> ;European Journal of Pharmacology. 1994 Jan 3
• Join now to see all