DouglasW.ScharreMD

Neurology • Columbus, OH

Neurodegenerative, Dementia & Geriatrics

Professor of Clinical Neurology and Psychiatry Ohio State University College of Medicine

Join to view full profile

Dr. Scharre is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Connect with other colleagues in the same hospital or clinic
Search all U.S. specialist profiles and refer a patient
Read the latest clinical news and earn CME/CEU credits

See Dr. Scharre's full profile

Already have an account?

Office
2050 Kenny Rd
Columbus, OH 43221
Phone+1 614-293-4969

Fax+1 614-293-1891
Is this information wrong?

Education & Training

Letterman Army Medical CenterResidency, Neurology, 1984 - 1987
William Beaumont Army Medical CenterInternship, Internal Medicine, 1983 - 1984
Georgetown University School of MedicineClass of 1983

Certifications & Licensure

CA State Medical License 1985 - Present
OH State Medical License 1993 - 2026
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013

Clinical Trials

Progress of Mild Alzheimer's Disease in Participants on Solanezumab Versus Placebo Start of enrollment: 2013 Jul 01
Terminated
Phase 3
A Study of LY3303560 in Participants With Mild Cognitive Impairment or Alzheimer's Disease Start of enrollment: 2017 Jan 31
Completed
Phase 1
Efficacy and Safety of MMFS in Early AD Start of enrollment: 2018 Mar 20
Completed
Phase 2
SAGE for the Early Detection of Cognitive Impairment at Primary Care Provider Visits Start of enrollment: 2019 Oct 14
Completed
Join now to see all

Publications & Presentations

PubMed

Imbalance in glucose metabolism regulates the transition of microglia from homeostasis to Disease Associated Microglia stage 1.
Yuxi Liu, Witty Kwok, Hyojung Yoon, Jae Cheon Ryu, Patrick Stevens, Tara R Hawkinson, Cameron J Shedlock, Roberto A Ribas, Terrymar Medina, Shannon B Keohane, Douglas ...> ;The Journal of Neuroscience. 2024 Apr 16
Detection of Cognitive Impairment From eSAGE Metadata Using Machine Learning.
Kawakami, R., Wright, K., Ning, X., Scharre, D.> ;Alzheimer Disease and Associated Disorders. 2023 Dec 13
1 citations
Potential Neuroprotective Effects of Dietary Omega-3 Fatty Acids on Stress in Alzheimer's Disease.
Kaitlyn B Hartnett, Bradley J Ferguson, Patrick M Hecht, Luke E Schuster, Joel I Shenker, David R Mehr, Kevin L Fritsche, Martha A Belury, Douglas W Scharre, Adam J Ho...> ;Biomolecules. 2023 Jul 8
3 citations
Explainable machine learning aggregates polygenic risk scores and electronic health records for Alzheimer's disease prediction.
Xiaoyi Raymond Gao, Marion Chiariglione, Ke Qin, Karen Nuytemans, Douglas W Scharre, Yi-Ju Li, Eden R Martin> ;Scientific Reports. 2023 Jan 9
19 citations
Spatially resolved transcriptomics reveals genes associated with the vulnerability of middle temporal gyrus in Alzheimer's disease.
Shuo Chen, Yuzhou Chang, Liangping Li, Diana Acosta, Yang Li, Qi Guo, Cankun Wang, Emir Turkes, Cody Morrison, Dominic Julian, Mark E Hester, Douglas W Scharre, Chintd...> ;Acta Neuropathologica Communications. 2022 Dec 21
The Dilemma of the Clinical Utility of Alzheimer Biomarker Evaluation in Everyday Clinical Practice: My Favorite PETs.
David Q Beversdorf, Douglas W Scharre> ;Neurology. 2023 Jan 17
21 citations
Wolframin is a novel regulator of tau pathology and neurodegeneration.
Shuo Chen, Diana Acosta, Liangping Li, Jiawen Liang, Yuzhou Chang, Cankun Wang, Julie Fitzgerald, Cody Morrison, Chris N Goulbourne, Yoshi Nakano, Nancy C Hernandez Vi...> ;Acta Neuropathologica. 2022 May 1
Correction to: Self-Administered Gerocognitive Examination: longitudinal cohort testing for the early detection of dementia conversion.
Douglas W Scharre, Shu Ing Chang, Haikady N Nagaraja, Natalie C Wheeler, Maria Kataki> ;Alzheimer's Research & Therapy. 2022 Feb 5
12 citations
Self-Administered Gerocognitive Examination: longitudinal cohort testing for the early detection of dementia conversion.
Douglas W Scharre, Shu Ing Chang, Haikady N Nagaraja, Natalie C Wheeler, Maria Kataki> ;Alzheimer's Research & Therapy. 2021 Dec 6
Race-Related Differences Between and Within Sex to Experimental Thermal Pain in Middle and Older Adulthood: An Exploratory Pilot Analysis
Karen O. Moss, Kathy D. Wright, Alai Tan, Karen M Rose, Douglas W. Scharre, Tanya R. Gure, Ronald L. Cowan, Michelle D. Failla, Todd B. Monroe> ;Frontiers in Pain Research. 2021 Nov 17
7 citations
Discriminating memory disordered patients from controls using diffusion model parameters from recognition memory.
Roger Ratcliff, Douglas W. Scharre, Gail McKoon> ;Journal of Experimental Psychology. General. 2021 Nov 4
2 citations
The Effect of Donepezil on Problem-solving Ability in Individuals With Amnestic Mild Cognitive Impairment: A Pilot Study.
David Q. Beversdorf, Haikady N. Nagaraja, Robert A. Bornstein, Douglas W. Scharre> ;Cognitive and Behavioral Neurology. 2021 Sep 2
1 citations
Treating the most vulnerable: A discursive review of experimental pain in Alzheimer's disease.
Wm Larkin Iversen, Ronald L. Cowan, Sebastian W. Atalla, Sydney S Englehart, Tanya R. Gure, Karen O. Moss, Claire M Ryan, Douglas W. Scharre, Kathy D. Wright, Todd B. ...> ;Nursing Open. 2021 Jun 24
2 citations
Immediate effects of treadmill walking in individuals with Lewy body dementia and Huntington’s disease
Deb A. Kegelmeyer, Sandra K. Kostyk, Nora E. Fritz, Douglas W. Scharre, Gregory S. Young, Yubo Tan, Robin Schubert, Ralf Reilmann, Anne D. Kloos> ;Gait & Posture. 2021 Mar 8
14 citations
Fluid and Tissue Biomarkers of Lewy Body Dementia: Report of an LBDA Symposium.
Gregory D Scott, Moriah R Arnold, Thomas G Beach, Christopher H Gibbons, Anumantha G Kanthasamy, Russell M Lebovitz, Afina W Lemstra, Leslie M Shaw, Charlotte E Teunis...> ;Frontiers in Neurology. 2021 Jan 1
8 citations
Mindfulness in Motion and Dietary Approaches to Stop Hypertension (DASH) in Hypertensive African Americans.
Kathy D. Wright, Maryanna Klatt, Ingrid Richards Adams, Christopher Nguyen, Lorraine C. Mion, Alai Tan, Todd B. Monroe, Karen M Rose, Douglas W. Scharre> ;Journal of the American Geriatrics Society. 2021 Mar 1
29 citations
Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration
Nicolai Franzmeier, M. Suárez-Calvet, Lukas Frontzkowski, Annah M. Moore, Timothy J. Hohman, Estrella Morenas-Rodríguez, Brigitte Nuscher, Leslie M. Shaw, John Q. Troj...> ;Molecular Neurodegeneration. 2020 Oct 8
6 citations
McLeod syndrome: Five new pedigrees with novel mutations
Joshua Weaver, Harini Sarva, Daniel A. Barone, Sarah M. Bobker, Khalaf Bushara, Amie L. Hiller, Makoto Ishii, Joseph Jankovic, Shenela Lakhani, K. Niotis, D.W. Scharre...> ;Parkinsonism & Related Disorders. 2019 May 2
8 citations
Lewy Body Dementia Association's Research Centers of Excellence Program: Inaugural Meeting Proceedings.
Bethany Peterson, Melissa J. Armstrong, Douglas Galasko, James E. Galvin, Jennifer G. Goldman, David J. Irwin, Henry L. Paulson, Daniel I. Kaufer, James B. Leverenz, A...> ;Alzheimer's Research & Therapy. 2019 Mar 13
3 citations
Cognitive self-assessment scales in surgical settings: Acceptability and feasibility.
Nicoleta Stoicea, K.N. Koehler, D.W. Scharre, Sergio D. Bergese> ;Best Practice & Research. Clinical Anaesthesiology. 2018 Sep 1
41 citations
Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states
Ines Mahjoub, Mohamed Ali Mahjoub, Islem Rekik, Michael W. Weiner, Paul S. Aisen, Ronald C. Petersen, Cliford Jack, William J. Jagust, John Q. Trojanowki, Arthur W. To...> ;Scientific Reports. 2018 Mar 7
7 citations
Alpha-synuclein mRNA isoform formation and translation affected by polymorphism in the human SNCA 3'UTR.
Elizabeth S. Barrie, Sung-Ha Lee, John T. Frater, Maria Kataki, Douglas W. Scharre, Wolfgang Sadee> ;Molecular Genetics & Genomic Medicine. 2018 May 6
35 citations
Deep Brain Stimulation of Frontal Lobe Networks to Treat Alzheimer's Disease.
Douglas W. Scharre, Emily R. Weichart, Dylan M. Nielson, Jun Zhang, Punit Agrawal, Per B. Sederberg, Michael V. Knopp, Ali R. Rezai> ;Journal of Alzheimer's Disease. 2018 Jan 1
Abstracts of the 33rd International Austrian Winter Symposium : Zell am See, Austria. 24-27 January 2018.
K Binzel, A Adelaja, C L Wright, D Scharre, J Zhang, M V Knopp, E J Teoh, D Bottomley, A Scarsbrook, H Payne, A Afaq, J Bomanji, N van As, S Chua, P Hoskin, A Chambers...> ;EJNMMI Research. 2018 Jan 23
6 citations
Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty
Lei Du, Kefei Liu, Xiaohui Yao, Jingwen Yan, Shannon L. Risacher, Junwei Han, Lei Guo, Andrew J. Saykin, Li Shen, Michael W. Weiner, Paul S. Aisen, Ronald C. Petersen,...> ;Scientific Reports. 2017 Dec 1
Join now to see all

Press Mentions

New Drug Shows Slowing in Cognitive Decline in Patients with Alzheimer's DiseaseMay 7th, 2023
New Treatments for Alzheimer’s DiseaseMarch 17th, 2023
Recognizing the Early Symptoms of DementiaFebruary 12th, 2023
Join now to see all