DouglasCharlesWallaceMD

PubMed

• 10 citations
  MitoScape: A big-data, machine-learning platform for obtaining mitochondrial DNA from next-generation sequencing data.
  Larry N. Singh, Brian Ennis, Bryn Loneragan, Noah L. Tsao, M Isabel G Lopez Sanchez, Jianping Li, Patrick Acheampong, Oanh Tran, Ian A. Trounce, Yuankun Zhu, Prasanth ...> ;Plos Computational Biology. 2021 Nov 11
• 41 citations
  Role of miR-2392 in driving SARS-CoV-2 infection.
  J. Tyson McDonald, Francisco J. Enguita, Deanne Taylor, Robert J. Griffin, Waldemar Priebe, Mark R. Emmett, Mohammad M. Sajadi, Anthony D. Harris, Jean Clement, Joseph...> ;Cell Reports. 2021 Oct 19
• 76 citations
  Mitochondrial DNA variation and cancer.
  Piotr K. Kopinski, Larry N. Singh, Shiping Zhang, Marie T. Lott, Douglas C. Wallace> ;Nature Reviews. Cancer. 2021 May 27
• 26 citations
  Association of Mitochondrial Biogenesis With Variable Penetrance of Schizophrenia
  Jianping Li, Oanh Tran, T. Blaine Crowley, Tyler M. Moore, Elaine H. Zackai, Beverly S. Emanuel, Donna M. McDonald-McGinn, Raquel E. Gur, Douglas C. Wallace, Stewart A...> ;JAMA Psychiatry. 2021 Aug 1
• 4 citations
  The Great Deceiver: miR-2392's Hidden Role in Driving SARS-CoV-2 Infection
  J. Tyson McDonald, Francisco J. Enguita, Robert J. Griffin, Waldemar Priebe, Mark R. Emmett, Mohammad M. Sajadi, Anthony D. Harris, Jean Clement, Nukhet Aykin-Burns, P...> ;Biorxiv. 2021 Apr 27
• 4 citations
  Decreased Intestinal Microbiome Diversity in Pediatric Sepsis: A Conceptual Framework for Intestinal Dysbiosis to Influence Immunometabolic Function.
  Scott L. Weiss, Kyle Bittinger, Jung-Jin Lee, Elliot S. Friedman, Lisa M. Mattei, Kathryn Graham, Donglan Zhang, Jeny Bush, Fran Balamuth, Francis X. McGowan, Frederic...> ;Critical Care Explorations. 2021 Mar 1
• 21 citations
  An mtDNA mutant mouse demonstrates that mitochondrial deficiency can result in autism endophenotypes
  Tal Yardeni, Ana G. Cristancho, Almedia J. McCoy, Patrick M. Schaefer, Meagan J. McManus, Eric D. Marsh, Douglas C. Wallace> ;Proceedings of the National Academy of Sciences of the United States of America. 2021 Feb 9
• 12 citations
  Genome-wide surveillance of transcription errors in response to genotoxic stress.
  Clark Fritsch, J.-F. Gout, Suraiya Haroon, A. Towheed, C. Chung, J. LaGosh, E. McGann, Xinmin Zhang, Yuanquan Song, Stephen Simpson, Prakroothi S. Danthi, Bérénice A. ...> ;Proceedings of the National Academy of Sciences of the United States of America. 2021 Jan 5
• 5 citations
  NADH fluorescence lifetime imaging microscopy reveals selective mitochondrial dysfunction in neurons overexpressing alzheimer’s disease–related proteins
  Moritz Niederschweiberer, Patrick M. Schaefer, Larry N. Singh, Ludwig Lausser, Devyani Bhosale, Raphael Hesse, Enrico Calzia, Hans A. Kestler, Angelika Rueck, Douglas ...> ;Frontiers in Molecular Biosciences. 2021 Jun 14
• 122 citations
  Lactate Limits T Cell Proliferation via the NAD(H) Redox State.
  William J. Quinn, Jing Jiao, Tara TeSlaa, Jason Stadanlick, Zhonglin Wang, Liqing Wang, Tatiana Akimova, Alessia Angelin, Patrick M. Schäfer, Michelle D. Cully, Caroli...> ;Cell Reports. 2020 Dec 15
• 24 citations
  Mitochondrial Nuclear Retrograde Regulator 1 (MNRR1) rescues the cellular phenotype of MELAS by inducing homeostatic mechanisms.
  Siddhesh Aras, Neeraja Purandare, Stephanie Gladyck, Mallika Somayajulu-Nitu, Kezhong Zhang, Douglas C. Wallace, Lawrence I. Grossman> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Dec 15
• 74 citations
  Specifications of the ACMG/AMP standards and guidelines for mitochondrial DNA variant interpretation.
  Elizabeth M. McCormick, Marie T. Lott, Matthew C. Dulik, Lishuang Shen, Marcella Attimonelli, Ornella Vitale, Amel Karaa, Renkui Bai, Daniel E. Pineda-Alvarez, Larry N...> ;Human Mutation. 2020 Dec 1
• 128 citations
  Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact.
  Willian A. da Silveira, Hossein Fazelinia, Sara Brin Rosenthal, Evagelia C. Laiakis, Man S. Kim, Cem Meydan, Yared H. Kidane, Komal S. Rathi, Scott M. Smith, Benjamin ...> ;Cell. 2020 Nov 25
• 116 citations
  Fundamental Biological Features of Spaceflight: Advancing the Field to Enable Deep-Space Exploration.
  Ebrahim Afshinnekoo, Ryan T Scott, Matthew J MacKay, Eloise Pariset, Egle Cekanaviciute, Richard Barker, Simon Gilroy, Duane Hassane, Scott M Smith, Sara R Zwart, Mayr...> ;Cell. 2020 Nov 25
• 16 citations
  Mitochondrial Dysfunction is Associated With an Immune Paralysis Phenotype in Pediatric Sepsis.
  Scott L. Weiss, Donglan Zhang, Jenny Bush, Kathryn Graham, Jonathan Starr, Jennifer B. Murray, Florin Tuluc, Sarah E. Henrickson, Clifford S. Deutschman, Lance B Becke...> ;Shock. 2020 Sep 1
• 1 citations
  CRISPR-Free Mitochondrial DNA Base Editing
  Douglas C. Wallace> ;The CRISPR Journal. 2020 Aug 1
• 1 citations
  An ultra-high bandwidth nano-electronic interface to the interior of living cells with integrated fluorescence readout of metabolic activity.
  Dandan Ren, Zahra Nemati, Chia-Hung Lee, Jinfeng Li, Kamel Haddadi, Douglas C. Wallace, Peter Burke> ;Scientific Reports. 2020 Jul 1
• 57 citations
  The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan.
  Kelvin Yen, Hemal H. Mehta, Su-Jeong Kim, Yanhe Lue, James Hoang, Noel Guerrero, Jenna Port, Qiuli Bi, Gerardo Navarrete, Sebastian Brandhorst, Kaitlyn N. Lewis, Junxi...> ;Aging. 2020 Jun 23
• 40 citations
  HDAC10 deletion promotes Foxp3+ T-regulatory cell function.
  Satinder Dahiya, Ulf H. Beier, Liqing Wang, Rongxiang Han, Jing Jiao, Tatiana Akimova, Alessia Angelin, Douglas C. Wallace, Wayne W. Hancock> ;Scientific Reports. 2020 Jan 16
• 57 citations
  Mitochondrial deficits in human iPSC-derived neurons from patients with 22q11.2 deletion syndrome and schizophrenia.
  Jianping Li, Sean K. Ryan, Erik M. DeBoer, Kieona Cook, Shane Fitzgerald, Herbert M. Lachman, Douglas C. Wallace, Ethan M. Goldberg, Stewart A. Anderson> ;Translational Psychiatry. 2019 Nov 18
• 117 citations
  The ADP/ATP translocase drives mitophagy independent of nucleotide exchange.
  , , , , , , , , , , , , , , , , , > ;Nature. 2019 Oct 16
• 26 citations
  Persistent Mitochondrial Dysfunction Linked to Prolonged Organ Dysfunction in Pediatric Sepsis.
  Scott L. Weiss, Donglan Zhang, Jenny Bush, Kathryn Graham, Jonathan Starr, Florin Tuluc, Sarah E. Henrickson, Todd J. Kilbaugh, Clifford S. Deutschman, Deborah G. Murd...> ;Critical Care Medicine. 2019 Oct 1
• 77 citations
  Unlocking the Secrets of Mitochondria in the Cardiovascular System: Path to a Cure in Heart Failure—A Report from the 2018 National Heart, Lung, and Blood Institute Wo...
  Rong Tian, Wilson S. Colucci, Zoltan Arany, Markus Bachschmid, Scott W. Ballinger, Sihem Boudina, James E. Bruce, David W. Busija, Sergey Dikalov, Gerald W. Dorn, Zori...> ;Circulation. 2019 Oct 1
• 19 citations
  BKCa (Slo) Channel Regulates Mitochondrial Function and Lifespan in Drosophila melanogaster.
  Shubha Gururaja Rao, Piotr Bednarczyk, Atif Towheed, Kajol Shah, Priyanka Karekar, Devasena Ponnalagu, Haley N Jensen, Sankar Addya, Beverly A.S. Reyes, Elisabeth J. V...> ;Cells. 2019 Aug 21
• 93 citations
  Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy.
  Piotr K. Kopinski, Kevin A. Janssen, Patrick M. Schaefer, Sophie Trefely, Caroline Perry, Prasanth Potluri, Jesus A Tintos-Hernandez, Larry N. Singh, Kelly R. Karch, S...> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Aug 6
• Join now to see all