ElizabethJMcFarlandMD

Pediatric Infectious Disease • Aurora, CO

Professor, Pediatrics, University of Colorado School of Medicine

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Office
Children's Hospital Colorado
13123 E 16th Ave
Aurora, CO 80045
Phone+1 720-777-1234
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Education & Training

University of ColoradoFellowship, Pediatric Infectious Diseases, 1992
University of ColoradoResidency, Pediatrics, 1985 - 1988
Duke University School of MedicineClass of 1985

Certifications & Licensure

CO State Medical License 1987 - 2025
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Infectious Diseases

Clinical Trials

Effects of Home Visits on Medication Adherence in Children and Youth With HIV
Unknown status
Not Applicable
Safety and Tolerability of a Therapeutic DNA Dendritic Cell Vaccine in HIV-Infected Children, Adolescents, and Young Adults
Withdrawn
Phase 1, Phase 2
IMPAACT 1077HS: Examining Benefits of HAART Continuation in Postpartum Women Start of enrollment: 2010 Jan 01
Completed
Phase 4
Surveillance Monitoring for ART Toxicities Study in HIV Uninfected Children Born to HIV Infected Women Start of enrollment: 2007 Mar 01
Recruiting
Connect to Protect (C2P): Building a Community-Based Infrastructure for HIV Prevention Start of enrollment: 2011 Nov 01
Completed
Not Applicable
An Open Label Demonstration Project and Phase II Safety Study of Pre-Exposure Prophylaxis Use Among 15 to 17 Year Old Young Men Who Have Sex With Men (YMSM) Start of enrollment: 2013 Mar 01
Completed
Phase 2
Two Part Study to Evaluate Pharmacokinetics, Safety, and Antiviral Activity of Elvitegravir Administered With a PI/r Background Regimen for ARV Treatment-Experienced Pediatric Participants Start of enrollment: 2013 Aug 26
Terminated
Phase 2, Phase 3
Study of Cobicistat-Boosted Atazanavir (ATV/co), Cobicistat-Boosted Darunavir (DRV/co) and Emtricitabine/Tenofovir Alafenamide (F/TAF) in Children With HIV Start of enrollment: 2014 Jan 16
Recruiting
Phase 2, Phase 3
Adolescent Master Protocol for Participants 18 Years of Age and Older (AMP Up) Start of enrollment: 2014 Apr 01
Recruiting
Safety and Immune Response to a Live-Attenuated Respiratory Syncytial Virus (RSV) Vaccine in RSV-Seronegative Infants and Children Start of enrollment: 2014 Sep 01
Completed
Phase 1
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Publications & Presentations

PubMed

7 citations
Evaluation of Recombinant Live-Attenuated Respiratory Syncytial Virus (RSV) Vaccines RSV/ΔNS2/Δ1313/I1314L and RSV/276 in RSV-Seronegative Children.
Coleen K Cunningham, Ruth A Karron, Petronella Muresan, Matthew S Kelly, Elizabeth J McFarland, Charlotte Perlowski, Jennifer Libous, Jennifer Oliva, Patrick Jean-Phil...> ;The Journal of Infectious Diseases. 2022 Dec 13
4 citations
Frequent Development of Broadly Neutralizing Antibodies in Early Life in a Large Cohort of Children With Human Immunodeficiency Virus.
Amanda Lucier, Youyi Fong, Shuk Hang Li, Maria Dennis, Joshua Eudailey, Ashley Nelson, Kevin Saunders, Coleen K Cunningham, Elizabeth McFarland, Ross McKinney, M Antho...> ;The Journal of Infectious Diseases. 2022 May 16
22 citations
Safety, Tolerability, and Pharmacokinetics of a Long-Acting Broadly Neutralizing HIV-1 Monoclonal Antibody VRC01LS in HIV-1-Exposed Newborn Infants.
Elizabeth J. McFarland, Coleen K. Cunningham, Petronella Muresan, Edmund V. Capparelli, Charlotte Perlowski, Patricia Morgan, Betsy Smith, Rohan Hazra, Lynette Purdue,...> ;The Journal of Infectious Diseases. 2021 May 2
172 citations
Risk Factors for Severe COVID-19 in Children.
Kelly Graff, Christiana Smith, Lori J. Silveira, Sarah Jung, Shane Curran-Hays, Jane Jarjour, Lauren Carpenter, Kasey Pickard, Michael Mattiucci, JoEllen Fresia, Eliza...> ;The Pediatric Infectious Disease Journal. 2021 Feb 1
Brief Report: Youth Living With Perinatally Acquired HIV Have Lower Physical Activity Levels as They Age Compared With HIV-Exposed Uninfected Youth.
Sahera Dirajlal-Fargo, Paige L. Williams, Carly Broadwell, Elizabeth J. McFarland, Kathleen M. Powis, Denise L. Jacobson, Jennifer Jao> ;Journal of Acquired Immune Deficiency Syndromes. 2021 May 1
5 citations
Model Informed Development of VRC01 in Newborn Infants Using a Population Pharmacokinetics Approach.
Jerry Li, Mina Nikanjam, Coleen K. Cunningham, Elizabeth J. McFarland, Emily E. Coates, Katherine V. Houser, Bob C. Lin, Adrian B. McDermott, Britta Flach, Lucio Gama,...> ;Clinical Pharmacology and Therapeutics. 2021 Jan 1
28 citations
Live-attenuated Vaccines Prevent Respiratory Syncytial Virus-associated Illness in Young Children.
Ruth A. Karron, Jessica E. Atwell, Elizabeth J. McFarland, Coleen K. Cunningham, Petronella Muresan, Charlotte Perlowski, Jennifer Libous, Stephen A. Spector, Ram Yoge...> ;American Journal of Respiratory and Critical Care Medicine. 2021 Mar 1
30 citations
Safety, Tolerability, and Pharmacokinetics of the Broadly Neutralizing Human Immunodeficiency Virus (HIV)-1 Monoclonal Antibody VRC01 in HIV-Exposed Newborn Infants.
Coleen K. Cunningham, Elizabeth J. McFarland, R Leavitt Morrison, Edmund V. Capparelli, Jeffrey T. Safrit, Lynne M. Mofenson, Bonnie J. Mathieson, Megan Valentine, Cha...> ;The Journal of Infectious Diseases. 2020 Jul 23
20 citations
Live-Attenuated Respiratory Syncytial Virus Vaccine With M2-2 Deletion and With Small Hydrophobic Noncoding Region Is Highly Immunogenic in Children
Elizabeth J. McFarland, Ruth A. Karron, Petronella Muresan, Coleen K. Cunningham, Charlotte Perlowski, Jennifer Libous, Jennifer Oliva, Patrick Jean-Philippe, Jack Moy...> ;The Journal of Infectious Diseases. 2020 Jun 11
21 citations
Live Respiratory Syncytial Virus Attenuated by M2-2 Deletion and Stabilized Temperature Sensitivity Mutation 1030s Is a Promising Vaccine Candidate in Children.
Elizabeth J. McFarland, Ruth A. Karron, Petronella Muresan, Coleen K. Cunningham, Jennifer Libous, Charlotte Perlowski, Bhagvanji Thumar, Devasena Gnanashanmugam, Jack...> ;The Journal of Infectious Diseases. 2020 Feb 3
7 citations
Birth Prevalence of Congenital Cytomegalovirus Infection in HIV-Exposed Uninfected Children in the Era of Combination Antiretroviral Therapy.
Murli Purswani, Jonathan S Russell, Monika L. Dietrich, Kathleen Malee, Stephen A. Spector, Paige L. Williams, Toni Frederick, Sandra K. Burchett, Sean M. Redmond, How...> ;The Journal of Pediatrics. 2019 Oct 23
20 citations
Human Papillomavirus Antibody Levels and Quadrivalent Vaccine Clinical Effectiveness in Perinatally Human Immunodeficiency Virus–infected and Exposed, Uninfected Youth
Anna-Barbara Moscicki, Brad Karalius, Katherine Tassiopoulos, Tzy-Jyun Yao, Denise L. Jacobson, Kunjal Patel, Murli Purswani, George R. Seage, Ram Yogev, Margaret Ann ...> ;Clinical Infectious Diseases. 2019 Sep 13
9 citations
A Comparison of Metabolic Outcomes Between Obese HIV-Exposed Uninfected Youth From the PHACS SMARTT Study and HIV-Unexposed Youth From the NHANES Study in the United S...
Jennifer Jao, Denise L. Jacobson, Wendy Yu, William Borkowsky, Mitchell E. Geffner, Elizabeth J. McFarland, Kunjal Patel, Paige L. Williams, Tracie L. Miller> ;Journal of Acquired Immune Deficiency Syndromes. 2019 Jul 1
12 citations
Live-Attenuated Respiratory Syncytial Virus Vaccine With Deletion of RNA Synthesis Regulatory Protein M2-2 and Cold Passage Mutations Is Overattenuated.
Coleen K. Cunningham, Ruth A. Karron, Petronella Muresan, Elizabeth J. McFarland, Charlotte Perlowski, Jennifer Libous, Bhagvanji Thumar, Devasena Gnanashanmugam, Jack...> ;Open Forum Infectious Diseases. 2019 May 6
20 citations
Development and application of a multiplex assay for the simultaneous measurement of antibody responses elicited by common childhood vaccines.
Hannah L. Itell, Erin McGuire, Petronella Muresan, Coleen K. Cunningham, Elizabeth J. McFarland, William Borkowsky, Sallie R. Permar, Genevieve G. Fouda> ;Vaccine. 2018 Sep 5
38 citations
Live Respiratory Syncytial Virus (RSV) Vaccine Candidate Containing Stabilized Temperature-Sensitivity Mutations Is Highly Attenuated in RSV-Seronegative Infants and C...
Ursula J. Buchholz, Coleen K. Cunningham, Petronella Muresan, Devasena Gnanashanmugam, Paul A. Sato, George K. Siberry, Vivian Rexroad, Megan Valentine, Charlotte Perl...> ;The Journal of Infectious Diseases. 2018 Apr 11
41 citations
Live-Attenuated Respiratory Syncytial Virus Vaccine Candidate With Deletion of RNA Synthesis Regulatory Protein M2-2 is Highly Immunogenic in Children.
Elizabeth J. McFarland, Ruth A. Karron, Petronella Muresan, Coleen K. Cunningham, Megan Valentine, Charlotte Perlowski, Bhagvanji Thumar, Devasena Gnanashanmugam, Geor...> ;The Journal of Infectious Diseases. 2018 Apr 11
5 citations
Improvement in lipids after switch to boosted atazanavir or darunavir in children/adolescents with perinatally acquired HIV on older protease inhibitors: results from ...
Jennifer Jao, Wendy Yu, Kunjal Patel, Tracie L. Miller, Brad Karalius, Mitchell E. Geffner, Linda A. DiMeglio, Ayesha Mirza, Janet S Chen, Margarita Silio, Elizabeth J...> ;HIV Medicine. 2018 Mar 1
25 citations
HIV-Exposed Infants Vaccinated with an MF59/Recombinant gp120 Vaccine Have Higher-Magnitude Anti-V1V2 IgG Responses than Adults Immunized with the Same Vaccine.
Erin McGuire, Youyi Fong, Christopher Toote, Coleen K. Cunningham, Elizabeth J. McFarland, William Borkowsky, Susan W. Barnett, Hannah L. Itell, Amit Kumar, Glenda Gra...> ;Journal of Virology. 2018 Jan 1
38 citations
HIV Continuum of Care for Youth in the United States.
Michelle A. Lally, Jacob J. van den Berg, Andrew O. Westfall, Bret J. Rudy, Sybil G. Hosek, Dina Monte, Mary Tanney, Elizabeth J. McFarland, Jiahong Xu, Bill G. Kapogi...> ;Journal of Acquired Immune Deficiency Syndromes. 2017 Oct 1
Update on Pediatric Human Immunodeficiency Virus Infection: Paradigms in Treatment and Prevention
Christiana Smith, Elizabeth J. McFarland> ;Advances in Pediatrics. 2016 Aug 1
15 citations
Decline in CD4 T lymphocytes with monotherapy bridging strategy for non-adherent adolescents living with HIV infection: Results of the IMPAACT P1094 randomized trial
Allison L. Agwu, Meredith G. Warshaw, Elizabeth J. McFarland, George K. Siberry, Ann J. Melvin, Andrew Wiznia, Lee Fairlie, Sandra Boyd, Paul Harding, Hans M. L. Spieg...> ;Plos One. 2017 Jun 12
19 citations
Growth at 2 Years of Age in HIV-exposed Uninfected Children in the United States by Trimester of Maternal Antiretroviral Initiation.
Denise L. Jacobson, Kunjal Patel, Paige L. Williams, Mitchell E. Geffner, George K. Siberry, Linda A. Dimeglio, Marilyn J. Crain, Ayesha Mirza, Janet S. Chen, Elizabet...> ;The Pediatric Infectious Disease Journal. 2017 Feb 1
6 citations
The interaction between equipoise and logistics in clinical trials: A case study
Meredith G. Warshaw, Vincent J. Carey, Elizabeth J. McFarland, Liza Dawson, Elaine J. Abrams, Ann J. Melvin, Lee Fairlie, Hans M. L. Spiegel, Jonathan Jay, Allison L. ...> ;Clinical Trials. 2017 Jan 31
3 citations
Ontogeny of CD4+ T Lymphocytes With Phenotypic Susceptibility to HIV-1 During Exclusive and Nonexclusive Breastfeeding in HIV-1-Exposed Ugandan Infants.
Elizabeth J. McFarland, Tina M. Powell, Carolyne Onyango-Makumbi, Weiming Zhang, Kelsey Melander, Prossy Naluyima, Samuel Okurut, Michael A. Eller, Mary Glenn Fowler, ...> ;The Journal of Infectious Diseases. 2016 Dec 8
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Journal Articles

Development and Application of a Multiplex Assay for the Simultaneous Measurement of Antibody Responses Elicited by Common Childhood Vaccines
Elizabeth J McFarland, Coleen K Cunningham, William Borkowsky, Sallie R Permar, ScienceDirect

Hospital Affiliations

Children's Hospital ColoradoAurora, Colorado
University of Colorado HospitalAurora, Colorado