EllenMayMandelMD

Pediatrics • Pittsburgh, PA

Associate Professor Emerita, Otolaryngology, University of Pittsburgh School of Medicine

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Office
1001 Highmont Road
Pittsburgh, PA 15232
Phone+1 412-361-0607
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Education & Training

Cincinnati Children's Hospital Medical CenterResidency, Pediatrics, 1975 - 1977
University of Pittsburgh School of MedicineClass of 1975

Certifications & Licensure

PA State Medical License 1977 - 2024
American Board of Pediatrics Pediatrics

Clinical Trials

Middle Ear Pressure Disregulation After Tympanostomy Tube Insertion Start of enrollment: 2006 Aug 01
Completed
Eustachian Tube Growth and Development Start of enrollment: 2006 Aug 01
Completed
Furlow Palatoplasty With Tensor Tenopexy Start of enrollment: 2012 Feb 28
Completed
Not Applicable
Eustachian Tube Function and Myringoplasty/Tympanoplasty Start of enrollment: 2012 Nov 01
Terminated
Trans-Middle-Ear Mucosal Gas Exchange Project 1, Specific Aim 1 Start of enrollment: 2014 May 13
Completed
Phase 1
Gas Supply, Demand and Middle Ear Gas Balance: Specific Aim 3 Start of enrollment: 2016 Dec 02
Terminated
Early Phase 1
TransMEM Gas Exchange -- Project 1, Aim 2 Start of enrollment: 2013 Oct 01
Completed
Phase 1
Gas Supply, Demand and Middle Ear Gas Balance -- Preliminary Protocol Start of enrollment: 2013 Oct 01
Completed
Not Applicable
Gas Supply, Demand and Middle Ear Gas Balance -- Diagnosis of Eustachian Tube Dysfunction Start of enrollment: 2013 Oct 01
Terminated
Not Applicable
Gas Supply, Demand and Middle Ear Gas Balance -- Fly/Dive Simulation Start of enrollment: 2014 Dec 02
Completed
Not Applicable
Balloon Dilation in Selected Subjects With Refractory Eustachian Tube Dysfunction Start of enrollment: 2014 Apr 01
Completed
Not Applicable
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Publications & Presentations

PubMed

33 citations
Panel 7: Otitis Media: Treatment and Complications
Anne G M Schilder, Tal Marom, Mahmood F. Bhutta, Margaretha L. Casselbrant, Harvey Coates, Marie Gisselsson-Solén, Amanda Hall, Paola Marchisio, Aino Ruohola, Roderick...> ;Otolaryngology--Head and Neck Surgery. 2017 Apr 3
13 citations
Resolution of Otitis Media With Effusion in Children With Cleft Palate Followed Through Five Years of Age.
Cuneyt M. Alper, Joseph E. Losee, James T. Seroky, Ellen M. Mandel, Beverly C. Richert, William J. Doyle> ;The Cleft Palate-Craniofacial Journal. 2016 Sep 1
4 citations
Information on co-morbidities collected by history is useful for assigning Otitis Media risk to children.
Margaretha L. Casselbrant, Ellen M. Mandel, William J. Doyle> ;International Journal of Pediatric Otorhinolaryngology. 2016 Jun 1
10 citations
Eustachian Tube Function in 6-Year-Old Children with and without a History of Middle Ear Disease
Ellen M. Mandel, Margaretha L. Casselbrant, Beverly C. Richert, Miriam S. Teixeira, J. Douglas Swarts, William J. Doyle> ;Otolaryngology--Head and Neck Surgery. 2016 Mar 1
26 citations
Predisposition to Childhood Otitis Media and Genetic Polymorphisms within the Toll-Like Receptor 4 (TLR4) Locus
Lena Hafrén, Elisabet Einarsdottir, Erna Kentala, Sari Hammarén-Malmi, Mahmood F. Bhutta, Carol J. MacArthur, Beth Wilmot, Margaretha L. Casselbrant, Yvette P. Conley,...> ;Plos One. 2015 Jul 15
5 citations
The forced‐response test does not discriminate ears with different otitis media expressions
Margaretha L. Casselbrant, Ellen M. Mandel, James T. Seroky, J. Douglas Swarts, William J. Doyle> ;The Laryngoscope. 2014 Nov 1
13 citations
Eustachian tube function in young children without a history of otitis media evaluated using a pressure chamber protocol.
John Douglas Swarts, Margaretha L. Casselbrant, Miriam S. Teixeira, Ellen M. Mandel, Beverly C. Richert, Juliane Banks, Jenna El-Wagaa, William J. Doyle> ;Acta Oto-Laryngologica. 2014 May 15
30 citations
A genome-wide association study of chronic otitis media with effusion and recurrent otitis media identifies a novel susceptibility locus on chromosome 2.
E. Kaitlynn Allen, Wei-Min Chen, Daniel E. Weeks, Fang Chen, Xuanlin Hou, Jose L. Mattos, Josyf C. Mychaleckyj, Fernando Segade, Margaretha L. Casselbrant, Ellen M. Ma...> ;Journal of the Association for Research in Otolaryngology. 2013 Aug 23
42 citations
Sensitivity and Specificity of Eustachian Tube Function Tests in Adults
William J. Doyle, J. Douglas Swarts, Julianne Banks, Margaretha L. Casselbrant, Ellen M. Mandel, Cuneyt M. Alper> ;JAMA Otolaryngology-- Head & Neck Surgery. 2013 Jul 1
26 citations
Eustachian tube function as a predictor of the recurrence of middle ear effusion in children
Ellen M. Mandel, J. Douglas Swarts, Margaretha L. Casselbrant, Kathleen K. Tekely, Beverly C. Richert, James T. Seroky, William J. Doyle> ;The Laryngoscope. 2013 Sep 1
7 citations
Panel 7: Treatment and comparative effectiveness research.
Paola Marchisio, Tasnee Chonmaitree, Eugene Leibovitz, Allan S. Lieberthal, Jørgen Lous, Ellen M. Mandel, David P. McCormick, Peter S. Morris, Aino Ruohola> ;Otolaryngology--Head and Neck Surgery. 2013 Apr 1
8 citations
The Cephalic Index is not different among groups of children aged 36-48 months with chronic otitis media with effusion, recurrent acute otitis media and controls.
Margaretha L. Casselbrant, J. Douglas Swarts, Ellen M. Mandel, William J. Doyle> ;International Journal of Pediatric Otorhinolaryngology. 2013 Mar 1
11 citations
Reproducibility of the forced response test in children with chronic otitis media with effusion.
William J. Doyle, Ellen M. Mandel, James T. Seroky, J. Douglas Swarts, Margaretha L. Casselbrant> ;Otology & Neurotology. 2013 Jan 1
2 citations
Treatment of Acute Otitis Media in Young Children
Ellen M. Mandel, Margaretha L. Casselbrant> ;Current Allergy and Asthma Reports. 2012 Sep 26
14 citations
Postpalatoplasty Eustachian tube function in young children with cleft palate.
Cuneyt M. Alper, Joseph E. Losee, Ellen M. Mandel, James T. Seroky, J. Douglas Swarts, William J. Doyle> ;The Cleft Palate-Craniofacial Journal. 2012 Jul 1
25 citations
Pre- and post-palatoplasty Eustachian tube function in infants with cleft palate
Cuneyt M. Alper, Joseph E. Losee, Ellen M. Mandel, James T. Seroky, J. Douglas Swarts, William J. Doyle> ;International Journal of Pediatric Otorhinolaryngology. 2012 Mar 1
8 citations
A Pilot Study of the Ability of the Forced Response Test to Discriminate Between 3-Year-Old Children with Chronic Otitis Media with Effusion or with Recurrent Acute Ot...
Margaretha L. Casselbrant, Ellen M. Mandel, James T. Seroky, J. Douglas Swarts, William J. Doyle> ;Acta Oto-Laryngologica. 2011 Oct 4
24 citations
Evaluation of 15 functional candidate genes for association with chronic otitis media with effusion and/or recurrent otitis media (COME/ROM).
Michèle M. Sale, Wei-Min Chen, Daniel E. Weeks, Josyf C. Mychaleckyj, Xuanlin Hou, Miranda C. Marion, Fernando Segade, Margaretha L. Casselbrant, Ellen M. Mandel, Robe...> ;Plos One. 2011 Aug 16
7 citations
Tympanostomy tube placement and vestibular function in children.
Michael S. Cohen, Ellen M. Mandel, Joseph M. Furman, Patrick J. Sparto, Margaretha L. Casselbrant> ;Otolaryngology--Head and Neck Surgery. 2011 Jun 15
25 citations
Eustachian Tube Function in Adults without Middle Ear Disease
J. Douglas Swarts, Cuneyt M. Alper, Ellen M. Mandel, Richard J. M. Villardo, William J. Doyle> ;The Annals of Otology, Rhinology, and Laryngology. 2011 Apr 1
Reply to Letter to the Editor.
Casselbrant, M.L., Mandel, E.M., Bluestone, C.D.> ;Int J Pediatr Otorhinolaryngol. 2010 Aug
29 citations
Longitudinal posturography and rotational testing in children three to nine years of age: normative data.
Margaretha L. Casselbrant, Ellen M. Mandel, Patrick J. Sparto, Subashan Perera, Mark S. Redfern, Patricia A. Fall, Joseph M. Furman> ;Otolaryngology--Head and Neck Surgery. 2010 May 1
21 citations
Post-tonsillectomy bleeding in children with von Willebrand disease: A single-institution experience
Kenneth D. Rodriguez, Gordon H. Sun, Francis Pike, Ellen M. Mandel, Margaretha L. Casselbrant, David H. Chi> ;Otolaryngology--Head and Neck Surgery. 2010 May 1
37 citations
Adenoidectomy for otitis media with effusion in 2-3-year-old children.
Margaretha L. Casselbrant, Ellen M. Mandel, Howard E. Rockette, Marcia Kurs-Lasky, P. Fall, Charles D. Bluestone> ;International Journal of Pediatric Otorhinolaryngology. 2009 Dec 1
31 citations
Otitis media: a genome-wide linkage scan with evidence of susceptibility loci within the 17q12 and 10q22.3 regions
Margaretha L. Casselbrant, Ellen M. Mandel, Jeesun Jung, Robert E. Ferrell, Kathleen K. Tekely, Jin P. Szatkiewicz, Amrita Ray, Daniel E. Weeks> ;BMC Medical Genetics. 2009 Sep 3
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Grant Support

Mepd After TT InsertionNational Institute On Deafness And Other Communication Disorders2009
Mepd After TT InsertionNational Institute On Deafness And Other Communication Disorders2006–2008
Water Precautions And Tympanostomy TubesNational Center For Research Resources1999–2002
Systemic Steroid For Chronic Otitis Media With EffusionNational Institute On Deafness And Other Communication Disorders1994–1996
Myringotomy With/Without Tympanostomy Tube For Otitis Media With EffusionNational Institute Of Neurological Disorders And Stroke1986–1988
Antibiotic For Otitis Media With EffusionNational Institute Of Neurological Disorders And Stroke1986–1988