EmilyHChengMD

PubMed

• 91 citations
  Chromosome 3p Loss-Orchestrated VHL, HIF, and Epigenetic Deregulation in Clear Cell Renal Cell Carcinoma.
  James J. Hsieh, Valerie H. Le, Toshinao Oyama, Christopher J. Ricketts, Thai H. Ho, Emily H. Cheng> ;Journal of Clinical Oncology. 2018 Oct 29
• 47 citations
  BH3-Dependent and Independent Activation of BAX and BAK in Mitochondrial Apoptosis.
  Paul S Jeng, Akane Inoue-Yamauchi, James J. Hsieh, Emily H. Cheng> ;Current Opinion in Physiology. 2018 Mar 20
• 84 citations
  Genomic classifications of renal cell carcinoma: a critical step towards the future application of personalized kidney cancer care with pan‐omics precision
  James J. Hsieh, Valerie H. Le, Dengfeng Cao, Emily H. Cheng, Chad J. Creighton> ;The Journal of Pathology. 2018 Apr 1
• 3466 citations
  Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
  Lorenzo Galluzzi, Ilio Vitale, Stuart A. Aaronson, John M. Abrams, Dieter Adam, Patrizia Agostinis, Emad S. Alnemri, Lucia Altucci, Ivano Amelio, David W. Andrews, Mar...> ;Cell Death and Differentiation. 2018 Jan 23
• 50 citations
  ΔNp63 Inhibits Oxidative Stress-Induced Cell Death, Including Ferroptosis, and Cooperates with the BCL-2 Family to Promote Clonogenic Survival.
  Gary X. Wang, Ho-Chou Tu, Yiyu Dong, Anders Jacobsen Skanderup, Yufeng Wang, Shugaku Takeda, Yogesh Tengarai Ganesan, Song Han, Han Liu, James J. Hsieh, Emily H. Cheng> ;Cell Reports. 2017 Dec 5
• 154 citations
  Genomic Biomarkers of a Randomized Trial Comparing First-line Everolimus and Sunitinib in Patients with Metastatic Renal Cell Carcinoma
  James J. Hsieh, David Chen, Patricia Wang, Mahtab Marker, Almedina Redzematovic, Ying-Bei Chen, S. Duygu Selcuklu, Nils Weinhold, Nancy Bouvier, Kety Huberman, Umesh B...> ;European Urology. 2017 Mar 1
• 6 citations
  Erratum: An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway (Molecular Cell (2016) 63(3) (485–497) (S1097276516302416) (10.1016/j.molcel.2016.06...
  Thomas P. Garner, Denis E. Reyna, Amit Priyadarshi, Hui Chen Chen, Sheng Li, Yang Wu, Yogesh Tengarai Ganesan, Vladimir N. Malashkevich, Emily H. Cheng, Evripidis Gava...> ;Molecular Cell. 2016 Oct 20
• An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway.
  Garner TP, Reyna DE, Priyadarshi A, Chen H, Li S, Wu Y, Ganesan YT, Malashkevich VN, Almo SS, Cheng EH, Gavathiotis E> ;Mol. Cell. 2016-08-04
• 432 citations
  An Integrated Metabolic Atlas of Clear Cell Renal Cell Carcinoma
  A. Ari Hakimi, Ed Reznik, Chung-Han Lee, Chad J. Creighton, A. Rose Brannon, Augustin Luna, B. Arman Aksoy, Eric Minwei Liu, Ronglai Shen, William Lee, Yang Chen, Stev...> ;Cancer Cell. 2016 Jan 11
• 193 citations
  An interconnected hierarchical model of cell death regulation by the BCL-2 family.
  Hui Chen Chen, Masayuki Kanai, Akane Inoue-Yamauchi, Ho-Chou Tu, Yafen Huang, Decheng Ren, Hyungjin Kim, Shugaku Takeda, Denis E. Reyna, Po M. Chan, Yogesh Tengarai Ga...> ;Nature Cell Biology. 2015 Oct 1
• 19 citations
  The TWEAK Receptor Fn14 Is an Src-Inducible Protein and a Positive Regulator of Src-Driven Cell Invasion.
  Emily Cheng, Timothy G. Whitsett, Nhan L. Tran, Jeffrey A. Winkles> ;Molecular Cancer Research. 2015 Mar 1
• 50 citations
  Minimizing the Non-specific Binding of Nanoparticles to the Brain Enables Active Targeting of Fn14-positive Glioblastoma Cells
  Craig S. Schneider, Jimena G. Perez, Emily Cheng, Clark Zhang, Panagiotis Mastorakos, Justin Hanes, Jeffrey A. Winkles, Graeme F. Woodworth, Anthony J. Kim> ;Biomaterials. 2015 Feb 1
• 667 citations
  Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
  Lorenzo Galluzzi, J M Bravo-San Pedro, Ilio Vitale, Stuart A. Aaronson, John M. Abrams, Dieter Adam, Emad S. Alnemri, Lucia Altucci, David W. Andrews, Margherita Annic...> ;Cell Death and Differentiation. 2015 Jan 1
• 280 citations
  Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion
  Ji Zhang, Jing Fan, Sriram Venneti, Justin R. Cross, Toshimitsu Takagi, Bhavneet Bhinder, Hakim Djaballah, Masayuki Kanai, Emily H. Cheng, Alexander R. Judkins, Bruce ...> ;Molecular Cell. 2014 Oct 23
• 27 citations
  Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis
  Yiyu Dong, Brian A. Van Tine, Toshinao Oyama, Patricia Wang, Emily H. Cheng, James J. Hsieh> ;Cell Research. 2014 Sep 30
• 19 citations
  Role of BH3-only molecules Bim and Puma in β-cell death in Pdx1 deficiency.
  Decheng Ren, Juan Sun, Changzheng Wang, Honggang Ye, Liqun Mao, Emily H. Cheng, Graeme I. Bell, Kenneth S. Polonsky> ;Diabetes. 2014 Aug 1
• 35 citations
  Proteasome Inhibitors Evoke Latent Tumor Suppression Programs in Pro-B MLL Leukemias through MLL-AF4
  Han Liu, Todd D. Westergard, Amanda F. Cashen, David Piwnica-Worms, Lori Kunkle, Ravi Vij, Can G. Pham, John F. DiPersio, Emily H. Cheng, James J. Hsieh> ;Cancer Cell. 2014 Apr 14
• 40 citations
  TWEAK/Fn14 Axis-Targeted Therapeutics: Moving Basic Science Discoveries to the Clinic.
  Emily Cheng, Cheryl L. Armstrong, Rebeca Galisteo, Jeffrey A. Winkles> ;Frontiers in Immunology. 2013 Dec 23
• 28 citations
  Cleavage of TFIIA by Taspase1 Activates TRF2-Specified Mammalian Male Germ Cell Programs
  Toshinao Oyama, Satoru Sasagawa, Shugaku Takeda, Rex A. Hess, Paul M. Lieberman, Emily H. Cheng, James J. Hsieh> ;Developmental Cell. 2013 Oct 28
• 166 citations
  Clinical and Pathologic Impact of Select Chromatin-modulating Tumor Suppressors in Clear Cell Renal Cell Carcinoma
  A. Ari Hakimi, Ying-Bei Chen, James Wren, Mithat Gonen, Omar Abdel-Wahab, Adriana Heguy, Han Liu, Shugaku Takeda, Satish K. Tickoo, Victor E. Reuter, Martin H. Voss, R...> ;European Urology. 2013 May 1
• 94 citations
  PUMA and BIM Are Required for Oncogene Inactivation–Induced Apoptosis
  Gregory R. Bean, Yogesh Tengarai Ganesan, Yiyu Dong, Shugaku Takeda, Han Liu, Po M. Chan, Yafen Huang, Lewis A. Chodosh, Gerard P. Zambetti, James J. Hsieh, Emily H. C...> ;Science Signaling. 2013 Mar 26
• 44 citations
  The TWEAK receptor Fn14 is a therapeutic target in melanoma: immunotoxins targeting Fn14 receptor for malignant melanoma treatment.
  Hong Zhou, Suhendan Ekmekcioglu, John W. Marks, Khalid A. Mohamedali, Kaushal Asrani, Keeley K. Phillips, Sharron A.N. Brown, Emily Cheng, Michele B. Weiss, Walter N. ...> ;The Journal of Investigative Dermatology. 2013 Apr 1
• 88 citations
  BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α.
  Diego A Rodriguez, Sebastian Zamorano, Fernanda Lisbona, Diego Rojas-Rivera, Hery Urra, Juan R Cubillos-Ruiz, Ricardo Armisen, Daniel R Henriquez, Emily H Cheng, Micha...> ;The EMBO Journal. 2012 May 16
• 34 citations
  A Pharmacologic Inhibitor of the Protease Taspase1 Effectively Inhibits Breast and Brain Tumor Growth
  David Y. Chen, Yishan Lee, Brian A. Van Tine, Adam C. Searleman, Todd D. Westergard, Han Liu, Ho-Chou Tu, Shugaku Takeda, Yiyu Dong, David Piwnica-Worms, Kyoung J. Oh,...> ;Cancer Research. 2012 Feb 1
• 86 citations
  A new pathway that regulates 53BP1 stability implicates Cathepsin L and vitamin D in DNA repair
  Ignacio Gonzalez-Suarez, Abena B. Redwood, David A Grotsky, Martin A. Neumann, Emily H. Cheng, Colin L. Stewart, Adriana Dusso, Susana Gonzalo> ;The EMBO Journal. 2011 Aug 17
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