ErikBKistlerMDPhD

Anesthesiology • San Diego, CA

Critical Care Medicine

Professor, Anesthesiology, UCSD School of Medicine

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Office
200 W Arbor Dr
San Diego, CA 92103
Phone+1 619-543-5297
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Education & Training

Massachusetts General HospitalFellowship, Critical Care Medicine, 2007 - 2008
University of California (San Diego) Medical CenterResidency, Anesthesiology, 2004 - 2007
Los Angeles County-Harbor-UCLA Medical CenterInternship, Transitional Year, 2003 - 2004
George Washington University School of Medicine and Health SciencesClass of 2003

Certifications & Licensure

CA State Medical License 2005 - 2024
MA State Medical License 2007 - 2024
American Board of Anesthesiology Anesthesiology
American Board of Anesthesiology Critical Care Medicine

Clinical Trials

Single Dose Enteral Tranexamic Acid in Critically Ill Patients Start of enrollment: 2012 Jun 01
Terminated
Phase 2

Publications & Presentations

PubMed

Enteral administration of the protease inhibitor gabexate mesilate preserves vascular function in experimental trauma/hemorrhagic shock.
Nathalia J D Moreira, Fernando Dos Santos, Joyce B Li, Federico Aletti, Maria Claudia C Irigoyen, Erik B Kistler> ;Scientific Reports. 2023 Jun 22
Efficacy of Tranexamic Acid in Blood Versus Crystalloid-Resuscitated Trauma/Hemorrhagic Shock.
Fernando Dos Santos, Joyce B Li, Rafi Mazor, Federico Aletti, Erik B Kistler> ;The Journal of Surgical Research. 2022 Nov 1
1 citations
Plasma enzymatic activity, proteomics and peptidomics in COVID-19-induced sepsis: A novel approach for the analysis of hemostasis.
Fernando Dos Santos, Joyce B Li, Nathalia Juocys, Rafi Mazor, Laura Beretta, Nicole G Coufal, Michael T Y Lam, Mazen F Odish, Maria Claudia Irigoyen, Anthony J O'Donog...> ;Frontiers in Molecular Biosciences. 2022 Jan 1
1 citations
Enteral gabexate mesilate improves volume requirements and autonomic cardiovascular function after experimental trauma/hemorrhagic shock in the absence of blood reperf...
Fernando Dos Santos, Joyce B Li, Nathalia Jd Moreira, Rafi Mazor, Federico Aletti, Erik B Kistler> ;American Journal of Translational Research. 2022 Jan 1
2 citations
Involvement of Toll-Like Receptor 4 in Decreased Vasopressor Response Following Trauma/Hemorrhagic Shock.
Rafi Mazor, Fernando Dos Santos, Joyce B. Li, Federico Aletti, Geert W. Schmid-Schönbein, Erik B. Kistler> ;Critical Care Explorations. 2021 Jul 1
16 citations
Resuscitation from hemorrhagic shock after traumatic brain injury with polymerized hemoglobin.
Cynthia R. Muller, Vasiliki Courelli, Alfredo Lucas, Alexander T. Williams, Joyce B. Li, Fernando Dos Santos, Clayton T. Cuddington, Savannah Moses, Andre F. Palmer, E...> ;Scientific Reports. 2021 Jan 28
5 citations
Continuous enteral protease inhibition as a novel treatment for experimental trauma/hemorrhagic shock.
Federico Aletti, Frank A. DeLano, Elisa Maffioli, Hao Mu, Geert W. Schmid-Schönbein, Gabriella Tedeschi, Erik B. Kistler> ;European Journal of Trauma and Emergency Surgery. 2021 Jan 22
7 citations
Resuscitation After Hemorrhagic Shock in the Microcirculation: Targeting Optimal Oxygen Delivery in the Design of Artificial Blood Substitutes
Carlos Munoz, Federico Aletti, Krianthan Govender, Pedro Cabrales, Erik B. Kistler> ;Frontiers in Medicine. 2020 Oct 27
24 citations
Gut Ischemia Reperfusion Injury Induces Lung Inflammation via Mesenteric Lymph-Mediated Neutrophil Activation.
Yonggang Ma, Taylor Zabell, Alexandra Creasy, Xiaoyuan Yang, Victor Chatterjee, Nuria Villalba, Erik B. Kistler, Mack H. Wu, Sarah Y. Yuan> ;Frontiers in Immunology. 2020 Sep 11
7 citations
High-Resolution Mass Spectrometry-Based Approaches for the Detection and Quantification of Peptidase Activity in Plasma
Elisa Maffioli, Zhenze Jiang, Simona Nonnis, Armando Negri, Valentina Romeo, Christopher B. Lietz, Vivian Hook, Giuseppe Ristagno, Giuseppe Baselli, Erik B. Kistler, F...> ;Molecules. 2020 Sep 6
18 citations
A longitudinal study highlights shared aspects of the transcriptomic response to cardiogenic and septic shock.
Daniele Braga, Matteo Barcella, Antoine Herpain, Federico Aletti, Erik B. Kistler, Bernardo Bollen Pinto, Karim Bendjelid, Cristina Barlassina> ;Critical Care. 2019 Dec 19
1 citations
Enteral Tranexamic Acid Decreases Proteolytic Activity in the Heart in Acute Experimental Hemorrhagic Shock.
Federico Aletti, Marco H. Santamaria, Kevin Chin, Rafi Mazor, Erik B. Kistler> ;Journal of Cardiovascular Pharmacology and Therapeutics. 2019 Apr 29
26 citations
Proteolysis in septic shock patients: plasma peptidomic patterns are associated with mortality
Julia Bauzá-Martinez, Federico Aletti, Bernardo Bollen Pinto, V. Ribas, Maria Antonia Odena, R. Díaz, Eduardo Romay, Ricard Ferrer, Erik B. Kistler, Gabriella Tedeschi...> ;British Journal of Anaesthesia. 2018 Nov 1
38 citations
Cleavage of the leptin receptor by matrix metalloproteinase–2 promotes leptin resistance and obesity in mice
Rafi Mazor, Dinorah Friedmann-Morvinski, Tom Alsaigh, Oded Kleifeld, Erik B. Kistler, Liat Rousso-Noori, Cheng Huang, Joyce B. Li, Inder M. Verma, Geert W. Schmid-Schö...> ;Science Translational Medicine. 2018 Aug 22
8 citations
Enteral tranexamic acid attenuates vasopressor resistance and changes in α1-adrenergic receptor expression in hemorrhagic shock.
Marco H. Santamaria, Federico Aletti, Joyce B. Li, Aaron Tan, Monica Chang, Jessica Leon, Geert W. Schmid-Schönbein, Erik B. Kistler> ;The Journal of Trauma and Acute Care Surgery. 2017 Aug 1
11 citations
Severity of Acute Kidney Injury in the Post-Lung Transplant Patient Is Associated With Higher Healthcare Resources and Cost.
Albert P. Nguyen, Rodney A. Gabriel, Eugene Golts, Erik B. Kistler, Ulrich Schmidt> ;Journal of Cardiothoracic and Vascular Anesthesia. 2017 Aug 1
4 citations
Preliminary profiling of blood transcriptome in a rat model of hemorrhagic shock.
Daniele Braga, Matteo Barcella, Francesca D'Avila, Sara Lupoli, F Tagliaferri, Marco H. Santamaria, Frank A. DeLano, Giuseppe Baselli, Geert W. Schmid-Schönbein, Erik ...> ;Experimental Biology and Medicine. 2017 Jun 29
2 citations
Set up of a protocol for rat plasma peptidomics in hemorrhagic shock model in presence of heparin
Elisa Maffioli, Federico Aletti, F. Santagata, Armando Negri, Marco H. Santamaria, Frank A. De Lano, Erik B. Kistler, Geert W. Schmid-Schönbein, Gabriella Tedeschi> ;Eupa Open Proteomics. 2016 Sep 1
19 citations
Peptidomic Analysis of Rat Plasma: Proteolysis in Hemorrhagic Shock.
Federico Aletti, Elisa Maffioli, Armando Negri, Marco H. Santamaria, Frank A. DeLano, Erik B. Kistler, Geert W. Schmid-Schönbein, Gabriella Tedeschi> ;Shock. 2016 May 1
18 citations
Autodigestion: Proteolytic Degradation and Multiple Organ Failure in Shock.
Angelina E. Altshuler, Erik B. Kistler, Geert W. Schmid-Schönbein> ;Shock. 2016 May 1
5 citations
Heparin Interaction with the Primed Polymorphonuclear Leukocyte CD11b Induces Apoptosis and Prevents Cell Activation.
Meital Cohen-Mazor, Rafi Mazor, Batya Kristal, Erik B. Kistler, Inbal Ziv, Judith Chezar, Shifra Sela> ;Journal of Immunology Research. 2015 Dec 27
16 citations
In vivo analysis of intestinal permeability following hemorrhagic shock.
Tom Alsaigh, Marisol Chang, Michael Richter, Rafi Mazor, Erik B. Kistler> ;World Journal of Critical Care Medicine. 2015 Nov 4
4 citations
Replacing the Transfusion of 1-2 Units of Blood with Plasma Expanders that Increase Oxygen Delivery Capacity: Evidence from Experimental Studies.
Amy G. Tsai, Beatriz Y. Salazar Vázquez, Pedro Cabrales, Erik B. Kistler, Daniel M. Tartakovsky, Shankar Subramaniam, Seetharama A. Acharya, Marcos Intaglietta> ;Journal of Functional Biomaterials. 2014 Oct 27
54 citations
Matrix metalloproteinase-1-mediated up-regulation of vascular endothelial growth factor-2 in endothelial cells.
Rafi Mazor, Tom Alsaigh, Helena Shaked, Angelina E. Altshuler, Elizabeth S. Pocock, Erik B. Kistler, Michael Karin, Geert W. Schmid-Schönbein> ;The Journal of Biological Chemistry. 2013 Jan 4
4 citations
An elementary analysis of physiologic shock and multi-organ failure: The Autodigestion Hypothesis
Geert W. Schmid Schönbein, Frank A. DeLano, Alexander H. Penn, Erik B. Kistler> ;Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2012 Jan 1
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