FinnJosephHawkinsMD

PubMed

• Loss of an extensive ciliary connectome induces proteostasis and cell fate switching in a severe motile ciliopathy.
  Steven L Brody, Jiehong Pan, Tao Huang, Jian Xu, Huihui Xu, Jeffrey Koenitizer, Steven K Brennan, Rashmi Nanjundappa, Thomas G Saba, Xiangli Wang, Rui Zhang, Moe R Mah...> ;Biorxiv. 2024 Mar 21
• Human iPSC-Based Model of COPD to Investigate Disease Mechanisms, Predict SARS-COV-2 Outcome, and Test Preventive Immunotherapy.
  Dagher, R., Moldobaeva, A., Gubbins, E., Clark, S., Madel Alfajaro, M., Wilen, C., Hawkins, F., Qu, X., Chien Chiang, C., Li, Y., Clarke, L., Ikeda, Y., Brown, C., Kol...> ;Stem Cells. 2024 Mar 14
• Viral airway injury promotes cell engraftment in an in vitro model of cystic fibrosis cell therapy.
  Rhianna E Lee, Teresa M Mascenik, Sidra C Major, Jacob R Galiger, Emily Bulik-Sullivan, Priscila F Siesser, Catherine A Lewis, James E Bear, Jake A Le Suer, Finn J Haw...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2024 Mar 1
• Uptake of Antifibrotics for Patients with Idiopathic Pulmonary Fibrosis: 2016-2022.
  Divya A Shankar, Finn Hawkins, Konstantinos-Dionysios Alysandratos, Kevin C Wilson, Nicholas A Bosch, Anica C Law, Allan J Walkey> ;Annals of the American Thoracic Society. 2024 Jan 1
• 1 citations
  Conditional blastocyst complementation of a defective Foxa2 lineage efficiently promotes the generation of the whole lung.
  Akihiro Miura, Hemanta Sarmah, Junichi Tanaka, Youngmin Hwang, Anri Sawada, Yuko Shimamura, Takehiro Otoshi, Yuri Kondo, Yinshan Fang, Dai Shimizu, Zurab Ninish, Jake ...> ;Elife. 2023 Oct 20
• 9 citations
  Airway stem cell reconstitution by the transplantation of primary or pluripotent stem cell-derived basal cells.
  Liang Ma, Bibek R Thapa, Jake A Le Suer, Andrew Tilston-Lünel, Michael J Herriges, Andrew Berical, Mary Lou Beermann, Feiya Wang, Pushpinder S Bawa, Anat Kohn, Alexand...> ;Cell Stem Cell. 2023 Sep 7
• 2 citations
  Generation of Pulmonary Ionocytes from Normal and Cystic Fibrosis Human Induced Pluripotent Stem Cells.
  Ruobing Wang, Chantelle Simone-Roach, Jonathan Lindstrom-Vautrin, Feiya Wang, Stuart Rollins, Pushpinder Singh Bawa, Junjie Lu, Yang Tang, Mary Lou Beermann, Thorsten ...> ;American Journal of Respiratory and Critical Care Medicine. 2023 May 1
• Hospital-level variation in practices and outcomes for patients with severe acute exacerbations of idiopathic pulmonary fibrosis: a retrospective multicentre cohort st...
  Divya A Shankar, Allan J Walkey, Finn J Hawkins, Nicholas A Bosch, Daniel Peterson, Anica C Law> ;BMJ Open Respiratory Research. 2023 Apr 1
• 11 citations
  A multimodal iPSC platform for cystic fibrosis drug testing.
  Berical, A., Lee, R., Lu, J., Beermann, M., Le Suer, J., Mithal, A., Thomas, D., Ranallo, N., Peasley, M., Stuffer, A., Bukis, K., Seymour, R., Harrington, J., Coote, ...> ;Nature Communications. 2022 Jul 29
• Generation of Airway Epithelial Cell Air-Liquid Interface Cultures from Human Pluripotent Stem Cells.
  Andrew Berical, Mary Lou Beermann, Shingo Suzuki, Jake LeSuer, Taylor Matte, Brian Davis, Darrell Kotton, Finn Hawkins> ;Journal of Visualized Experiments. 2022 Jun 14
• 10 citations
  Human airway lineages derived from pluripotent stem cells reveal the epithelial responses to SARS-CoV-2 infection.
  Ruobing Wang, Adam J Hume, Mary Lou Beermann, Chantelle Simone-Roach, Jonathan Lindstrom-Vautrin, Jake Le Suer, Jessie Huang, Judith Olejnik, Carlos Villacorta-Martin,...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2022 Mar 1
• 15 citations
  Recapitulating human cardio-pulmonary co-development using simultaneous multilineage differentiation of pluripotent stem cells.
  Wai Hoe Ng, Elizabeth K Johnston, Jun Jie Tan, Jacqueline M Bliley, Adam W Feinberg, Donna B Stolz, Ming Sun, Piyumi Wijesekara, Finn Hawkins, Darrell N Kotton, Xi Ren> ;Elife. 2022 Jan 12
• 4 citations
  Differentiation of human pluripotent stem cells into functional airway basal stem cells.
  Shingo Suzuki, Finn Hawkins, Cristina Barillà, Mary Lou Beermann, Darrell N. Kotton, Brian R. Davis> ;STAR Protocols. 2021 Jul 20
• 1 citations
  Primary pulmonary marginal zone lymphoma: an unusual cause of pulmonary infiltrates
  John Mark Sloan, Eric J. Burks, Finn Hawkins, Robert Smyth> ;Respirology Case Reports. 2021 Jun 29
• 90 citations
  Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells
  Finn Hawkins, Shingo Suzuki, Mary Lou Beermann, Cristina Barillà, Ruobing Wang, Carlos Villacorta-Martin, Andrew Berical, Jyh-Chang Jean, Jake Le Suer, Taylor Matte, C...> ;Cell Stem Cell. 2021 Jan 7
• 183 citations
  SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response
  Jessie Huang, Adam J. Hume, Kristine M. Abo, Rhiannon B. Werder, Carlos Villacorta-Martin, Konstantinos-Dionysios Alysandratos, Mary Lou Beermann, Chantelle Simone-Roa...> ;Cell Stem Cell. 2020 Dec 3
• 13 citations
  Correction of Airway Stem Cells: Genome Editing Approaches for the Treatment of Cystic Fibrosis
  Nicholas E King, Shingo Suzuki, Cristina Barillà, Finn Hawkins, Scott H. Randell, Susan D. Reynolds, Barry R. Stripp, Brian R. Davis> ;Human Gene Therapy. 2020 Sep 16
• 47 citations
  SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response.
  Jessie Huang, Adam J. Hume, Kristine M. Abo, Rhiannon B. Werder, Carlos Villacorta-Martin, Konstantinos-Dionysios Alysandratos, Mary Lou Beermann, Chantelle Simone-Roa...> ;Biorxiv. 2020 Jun 30
• 10 citations
  Differentiation of human airway-organoids from induced pluripotent stem cells (iPSCs).
  Ruobing Wang, Katie B McCauley, Darrell N. Kotton, Finn Hawkins> ;Methods in Cell Biology. 2020 Jan 1
• 34 citations
  Human iPSC-derived alveolar and airway epithelial cells can be cultured at air-liquid interface and express SARS-CoV-2 host factors
  Kristine M. Abo, Liang Ma, Taylor Matte, Jessie Huang, Konstantinos D. Alysandratos, Rhiannon B. Werder, Aditya Mithal, Mary Lou Beermann, Jonathan Lindstrom-Vautrin, ...> ;Biorxiv. 2020 Jun 4
• 36 citations
  Precise Targeting of miRNA Sites Restores CFTR Activity in CF Bronchial Epithelial Cells.
  Chiara De Santi, Elena Fernández Fernández, Rachel Gaul, Sebastian Vencken, Arlene Glasgow, Irene Oglesby, Killian Hurley, Finn Hawkins, Nilay Mitash, Fangping Mu, Ran...> ;Molecular Therapy. 2020 Apr 8
• 62 citations
  Generation of mesenchyme free intestinal organoids from human induced pluripotent stem cells
  Aditya Mithal, Amalia Capilla, Dar Heinze, Andrew Berical, Carlos Villacorta-Martin, Marall Vedaie, Anjali Jacob, Kristine M. Abo, Aleksander D. Szymaniak, Megan Peasl...> ;Nature Communications. 2020 Jan 10
• 113 citations
  Derivation of self-renewing lung alveolar epithelial type II cells from human pluripotent stem cells.
  Anjali Jacob, Marall Vedaie, David A Roberts, Dylan C. Thomas, Carlos Villacorta-Martin, Konstantinos-Dionysios Alysandratos, Finn Hawkins, Darrell N. Kotton> ;Nature Protocols. 2019 Nov 15
• 7 citations
  Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Diseases 2017. An Official American Thoracic Society Workshop Report.
  Amy L. Ryan, Laertis Ikonomou, Sadaf Atarod, Deniz A. Bölükbas, Jennifer J.P. Collins, Rob Freishtat, Finn Hawkins, Sarah E. Gilpin, Franziska E. Uhl, Juan J. Uriarte,...> ;American Journal of Respiratory Cell and Molecular Biology. 2019 Oct 1
• 41 citations
  Challenges Facing Airway Epithelial Cell-Based Therapy for Cystic Fibrosis.
  Andrew Berical, Rhianna E. Lee, Scott H. Randell, Finn Hawkins> ;Frontiers in Pharmacology. 2019 Feb 8
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