FitzroyWDawkinsMD

Oncology • Malvern, PA

Director, Clinical Research, Janssen Pharmaceutical Company

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Office
200 Great Valley Pkwy
Malvern, PA 19355
Phone+1 610-240-8321
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Education & Training

George Washington UniversityFellowship, Hematology and Medical Oncology, 1988 - 1991
Jacobs School of Medicine and Biomedical Sciences at the University at BuffaloClass of 1984

Certifications & Licensure

DC State Medical License 1990 - 2018
American Board of Internal Medicine Internal Medicine

Clinical Trials

Study of Ruxolitinib in Pancreatic Cancer Patients (Janus 1) Start of enrollment: 2014 Mar 01
Terminated
Phase 3
A Study of Ruxolitinib in Pancreatic Cancer Patients Start of enrollment: 2014 Jun 01
Terminated
Phase 3
A Study of Itacitinib (INCB039110) in Combination With Ibrutinib in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma Start of enrollment: 2016 Dec 29
Completed
Phase 1, Phase 2
An Open-Label Study to Enable Continued Treatment Access for Subjects Previously Enrolled in Studies of Ruxolitinib Start of enrollment: 2016 Nov 30
Active, not recruiting
Phase 2
A Phase 2 Safety and Efficacy Study of INCB050465 in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (CITADEL-202) Start of enrollment: 2017 Mar 02
Completed
Phase 2
Study Evaluating Safety and Efficacy of INCB050465 Combined With Bendamustine and Obinutuzumab in Relapsed or Refractory Follicular Lymphoma (CITADEL-102) Start of enrollment: 2017 Feb 15
Completed
Phase 1
A Study of INCB050465 in Relapsed or Refractory Follicular Lymphoma Start of enrollment: 2018 Mar 14
Active, not recruiting
Phase 2
A Study to Evaluate Safety, Pharmacokinetic, and Biological Activity of INCB059872 in Subjects With Sickle Cell Disease Start of enrollment: 2017 Apr 20
Terminated
Phase 1
A Study of INCB050465 in Subjects With Relapsed or Refractory Marginal Zone Lymphoma (CITADEL-204) Start of enrollment: 2017 Dec 18
Active, not recruiting
Phase 2
A Study of INCB050465 in Japanese Subjects With Previously Treated B-Cell Lymphoma (CITADEL-111) Start of enrollment: 2018 Aug 02
Completed
Phase 1
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Publications & Presentations

PubMed

147 citations
Ruxolitinib for the treatment of steroid-refractory acute GVHD (REACH1): A multicenter, open-label phase 2 trial
Madan Jagasia, Miguel-Angel Perales, Mark A. Schroeder, Haris Ali, Nirav N. Shah, Yi-Bin Chen, Salman Fazal, Fitzroy Dawkins, Michael C. Arbushites, Chuan Tian, Laura ...> ;Blood. 2020 May 14
8 citations
Pain questionnaire performance in advanced prostate cancer: comparative results from two international clinical trials
Don Robinson, Ning Zhao, Fitzroy Dawkins, Ming Qi, Dennis A. Revicki> ;Quality of Life Research. 2013 Apr 16
28 citations
Screening for iron overload: Lessons from the HEmochromatosis and IRon Overload Screening (HEIRS) Study
Paul C. Adams, James C. Barton, Gordon D. McLaren, Ronald T. Acton, Mark Speechley, Christine E. McLaren, David M. Reboussin, Catherine Leiendecker-Foster, Emily L. Ha...> ;Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie. 2009 Nov 1
2 citations
Upper gastrointestinal bleeding from metastatic testicular cancer.
Adeyinka O. Laiyemo, Momodu Jack, Fitzroy W. Dawkins, Duane T. Smoot> ;Journal of the National Medical Association. 2009 Aug 1
1 citations
Ferritin and increased vs upper reference interval tibc saturation to identify increased iron stores in African Americans
Onyinye Onyekwere, P. Kamineni, T.N. Johnson-Largent, Margaret Fadojutimi-Akinsiku, Fitzroy W. Dawkins, Victor R. Gordeuk> ;Clinica Chimica Acta; International Journal of Clinical Chemistry. 2009 Jul 1
37 citations
Serum ferritin concentrations and body iron stores in a multicenter, multiethnic primary-care population.
Victor R. Gordeuk, David M. Reboussin, Christine E. McLaren, James C. Barton, Ronald T. Acton, Gordon D. McLaren, Emily L. Harris, Jacob A. Reiss, Paul C. Adams, Mark ...> ;American Journal of Hematology. 2008 Aug 1
5 citations
Serial serum ferritin measurements in untreated HFE C282Y homozygotes in the Hemochromatosis and Iron Overload Screening Study
Paul C. Adams, David M. Reboussin, James C. Barton, Ronald T. Acton, Mark Speechley, C. Leiendecker-Foster, R. Meenan, Leah Passmore, Christine E. McLaren, Gordon D. M...> ;International Journal of Laboratory Hematology. 2008 Aug 1
6 citations
Characteristics of participants with self‐reported hemochromatosis or iron overload at HEIRS study initial screening
James C. Barton, Ronald T. Acton, Catherine Leiendecker-Foster, Laura C. Lovato, Paul C. Adams, John H. Eckfeldt, Christine E. McLaren, Jacob A. Reiss, Gordon D. McLar...> ;American Journal of Hematology. 2008 Feb 1
47 citations
Clinical manifestations of hemochromatosis in HFE C282Y homozygotes identified by screening.
Gordon D. McLaren, Christine E. McLaren, Paul C. Adams, James C. Barton, David M. Reboussin, Victor R. Gordeuk, Ronald T. Acton, Emily L. Harris, Mark Speechley, Phyli...> ;Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie. 2008 Nov 1
63 citations
Biological variability of transferrin saturation and unsaturated iron binding capacity
Paul C. Adams, David M. Reboussin, Richard D. Press, James C. Barton, Ronald T. Acton, Godfrey C. Moses, Catherine Leiendecker-Foster, Gordon D. McLaren, Fitzroy W. Da...> ;The American Journal of Medicine. 2007 Nov 1
6 citations
HFE C282Y homozygotes aged 25-29 years at HEIRS Study initial screening.
James C. Barton, Ronald T. Acton, Catherine Leiendecker-Foster, Laura C. Lovato, Paul C. Adams, Gordon D. McLaren, John H. Eckfeldt, Christine E. McLaren, David M. Reb...> ;Genetic Testing. 2007 Oct 21
7 citations
African Americans at Risk for Increased Iron Stores or Liver Disease
Fitzroy W. Dawkins, Victor R. Gordeuk, Beverly M. Snively, Laura C. Lovato, James C. Barton, Ronald T. Acton, Gordon D. McLaren, Catherine Leiendecker-Foster, Christin...> ;The American Journal of Medicine. 2007 Aug 1
10 citations
A genome-wide linkage scan for iron phenotype quantitative trait loci: the HEIRS Family Study.
Ronald T. Acton, Beverly M. Snively, James C. Barton, Christine E. McLaren, Paul C. Adams, S. S. wRich, John H. Eckfeldt, Richard D. Press, Phyliss Sholinsky, C. Leien...> ;Clinical Genetics. 2007 Jun 1
37 citations
Association of ferroportin Q248H polymorphism with elevated levels of serum ferritin in African Americans in the Hemochromatosis and Iron Overload Screening (HEIRS) Study
Charles A. Rivers, James C. Barton, Victor R. Gordeuk, Ronald T. Acton, Mark Speechley, Beverly M. Snively, Catherine Leiendecker-Foster, Richard D. Press, Paul C. Ada...> ;Blood Cells, Molecules & Diseases. 2007 May 1
31 citations
Geographic and racial/ethnic differences in HFE mutation frequencies in the Hemochromatosis and Iron Overload Screening (HEIRS) Study.
Ronald T. Acton, Jackson C. Barton, Beverly M. Snively, Christine E. McLaren, Paul C. Adams, Emily L. Harris, Mark R. Speechley, Gordon D. McLaren, Fitzroy W. Dawkins,...> ;Ethnicity & Disease. 2006 Jan 1
7 citations
Mixture models of serum iron measures in population screening for hemochromatosis and iron overload.
Christine E. McLaren, Kuo Tung Li, Gordon D. McLaren, Victor R. Gordeuk, Beverly M. Snively, David M. Reboussin, James C. Barton, Ronald T. Acton, Fitzroy W. Dawkins, ...> ;Translational Research. 2006 Oct 1
63 citations
Relationships of Serum Ferritin, Transferrin Saturation, and HFE Mutations and Self-Reported Diabetes in the Hemochromatosis and Iron Overload Screening (HEIRS) Study
Ronald T. Acton, James C. Barton, Leah Passmore, Paul C. Adams, Mark Speechley, Fitzroy W. Dawkins, Phyliss Sholinsky, David M. Reboussin, Gordon D. McLaren, Emily L. ...> ;Diabetes Care. 2006 Sep 1
Case of chronic eosinophilic leukemia with deletion of chromosome 16 and hepatitis C.
Padma Kamineni, Ayanna Baptiste, Mukhtar Hassan, Fitzroy W. Dawkins, Syed I. Zaidi, Ayalew Tefferi, Mercedes Lindsey, Lekidelu Taddesse-Heath> ;Journal of the National Medical Association. 2006 Aug 1
45 citations
Liver diseases in the hemochromatosis and iron overload screening study.
Paul C. Adams, Leah Passmore, Subrata Chakrabarti, David M. Reboussin, Ronald T. Acton, James C. Barton, Gordon D. McLaren, John H. Eckfeldt, Fitzroy W. Dawkins, Victo...> ;Clinical Gastroenterology and Hepatology. 2006 Jul 1
29 citations
The association of serum ferritin and transferrin receptor concentrations with mortality in women with human immunodeficiency virus infection.
Victor R Gordeuk, Gladys Onojobi, Michael F Schneider, Fitzroy W Dawkins, Robert Delapenha, Yaroslav Voloshin, Victor von Wyl, Melanie Bacon, Howard Minkoff, Alexandra...> ;Haematologica. 2006 Jun 1
6 citations
Low cobalamin levels in African Americans with and without sickle cell disease.
Padma Kamineni, Suguna Chirla, Kimberly Dinh, Syed Hasan, Emmanuel A. Nidhiry, John Kwagyan, Tammey Naab, Fredric A. Lombardo, Oswaldo Castro, Fitzroy W. Dawkins> ;Journal of the National Medical Association. 2006 Mar 1
23 citations
Initial screening transferrin saturation values, serum ferritin concentrations, and HFE genotypes in Native Americans and whites in the Hemochromatosis and Iron Overlo...
James C. Barton, Ronald T. Acton, Laura C. Lovato, Speechley, Christine E. McLaren, Emily L. Harris, David M. Reboussin, Paul C. Adams, Fitzroy W. Dawkins, Victor R. G...> ;Clinical Genetics. 2005 Oct 14
58 citations
Initial screening transferrin saturation values, serum ferritin concentrations, and HFE genotypes in whites and blacks in the Hemochromatosis and Iron Overload Screeni...
James C. Barton, Ronald T. Acton, Fitzroy W. Dawkins, Paul C. Adams, Laura C. Lovato, Cathie Leiendecker-Foster, Christine E. McLaren, David M. Reboussin, Mark Speechl...> ;Genetic Testing. 2005 Jan 1
102 citations
A phase II study of bortezomib in the treatment of metastatic malignant melanoma.
Svetomir N. Markovic, Susan Geyer, Fitzroy Dawkins, William Sharfman, Mark Albertini, William Maples, Paula M. Fracasso, Tom Fitch, D O Patricia LoRusso, Alex A. Adjei...> ;Cancer. 2005 Jun 15
20 citations
Apoptosis induced by aspirin and 5-fluorouracil in human colonic adenocarcinoma cells.
Hassan Ashktorab, Fitzroy W. Dawkins, Rihab Mohamed, Daniel Larbi, Duane T. Smoot> ;Digestive Diseases and Sciences. 2005 Jun 1
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Press Mentions

Forma Therapeutics : Appoints Two New Vice Presidents to Lead Key Organizational FunctionsSeptember 15th, 2020
Clinical Manifestations of Hemochromatosis in HFE C282Y Homozygotes Identified by ScreeningJuly 20th, 2019