Dr. Frederick Locke is an oncologist in Tampa, FL and is affiliated with H. Lee Moffitt Cancer Center and Research Institute. He received his medical degree from Wayne State University School of Medicine and has been in practice 15 years. He specializes in hematologic oncology and is experienced in hematopoietic stem cell transplantation, non-hodgkin's lymphoma, immunology, and chimeric antigen receptor (CAR) t-cell therapy.
Aimaz Afrough, Hamza Hashmi, Doris K Hansen, Surbhi Sidana, Chul Ahn, Lauren C Peres, Danai Dima, Ciara L Freeman, Omar Castaneda Puglianini, Mehmet H Kocoglu, Shebli ...> ;Blood Cancer Journal. 2024 Apr 12
John Kuruvilla, Catherine Thieblemont, Franck Morschhauser, Steven P Rowe, Saran Vardhanabhuti, Joshua Winters, Simone Filosto, Christina To, Paul Cheng, Marco Schupp,...> ;Blood. 2024 Apr 1
Matthew A Lunning, Hai-Lin Wang, Zhen-Huan Hu, Frederick L Locke, Tanya Siddiqi, Caron A Jacobson, Sairah Ahmed, David B Miklos, Yi Lin, Brian T Hill, Armin Ghobadi, S...> ;American Journal of Hematology. 2024 May 1
Dean, E., Rawan G Faramand, Sae Bom Lee, Michael D Jain, Biwei Cao, Xuefeng Wang, Kai Rejeski, Marion Subklewe, Johannes F Fahrmann, Neeraj Y Saini, Samir M Hanash, Yu...> ;Blood Cancer Discovery. 2024 Mar 1
Othman S Akhtar, Karnav Modi, Jongphil Kim, Lawrence Skelson, Eric Smith, Mohammed A Al-Jumayli, Martine Extermann, Gabriel De Avila, Nathan Parker, Omar Castaneda Pug...> ;Transplantation and Cellular Therapy. 2024 Mar 1
Michael D Jain, Miriam T Jacobs, Feng Gao, Loretta J Nastoupil, Jay Y Spiegel, Yi Lin, Saurabh Dahiya, Matthew Lunning, Lazaros Lekakis, Patrick Reagan, Olalekan Oluwo...> ;Blood Advances. 2024 Feb 27
Julio C Chavez, Ariel Grajales, Jose Sandoval-Sus, Elyce Turba, Lisa Nodzon, Angimar Uriepero-Palma, Mohammad Ammad-Ud-Din, Eva Sahakian, Rami Komrokji, Lubomir Sokol,...> ;Clinical Lymphoma, Myeloma & Leukemia. 2024 Feb 13
Ghobadi, A., Munoz, J., Westin, J., Locke, F., Miklos, D., Rapoport, A., Perales, M., Reagan, P., McGuirk, J., Jacobson, C., Kersten, M., Avivi, I., Peng, A., Schupp, ...> ;Blood Advances. 2024 Feb 5
Lauren C Peres, Laura B Oswald, Christen M Dillard, Gabriel De Avila, Taiga Nishihori, Brandon J Blue, Ciara L Freeman, Frederick L Locke, Melissa Alsina, Omar Castane...> ;Blood Advances. 2024 Jan 9
Levine, B., Pasquini, M., Connolly, J., Porter, D., Gustafson, M., Boelens, J., Horwitz, E., Grupp, S., Maus, M., Locke, F., Ciceri, F., Ruggeri, A., Snowden, J., Hesl...> ;Nature Medicine. 2024 Feb 1
Olalekan O Oluwole, Bhagirathbhai Dholaria, Tristan E Knight, Tania Jain, Frederick L Locke, Linda Ramsdell, Sarah Nikiforow, Hamza Hashmi, Kathy Mooney, Shakthi T Bha...> ;Transplantation and Cellular Therapy. 2024 Feb 1
Laura B Oswald, Lisa M Gudenkauf, Xiaoyin Li, Gabriel De Avila, Lauren C Peres, Kedar Kirtane, Brian D Gonzalez, Aasha I Hoogland, Oanh Nguyen, Yvelise Rodriguez, Rach...> ;Cancers. 2023 Sep 25
Surbhi Sidana, Lauren C Peres, Hamza Hashmi, Hitomi Hosoya, Christopher Ferreri, Jack Khouri, Danai Dima, Shebli Atrash, Peter Voorhees, Gary Simmons, Douglas W Sborov...> ;Haematologica. 2024 Mar 1
Zurko, J. C., Rezvani, A. R., Narendranath Epperla, Ambuj Kumar, Syed A Abutalib, Farrukh T Awan, Yi-Bin Chen, Ajay K Gopal, Jennifer Holter-Chakrabarty, Natasha Kekre...> ;Transplantation and Cellular Therapy. 2023 Sep 1
Kai Rejeski, Yucai Wang, Omar Albanyan, Javier Munoz, Pierre Sesques, Gloria Iacoboni, Lucia Lopez-Corral, Isabelle Ries, Veit L Bücklein, Razan Mohty, Martin Dreyling...> ;American Journal of Hematology. 2023 Nov 1
A Comparison of Two-Year Outcomes in ZUMA-1 (Axicabtagene Ciloleucel) and SCHOLAR-1 in Patients with Refractory Large B Cell Lymphoma
Frederick L. Locke, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Panobinostat As a Maintenance Therapy after Autologous Hematopoietic Cell Transplantation for Patients with Multiple Myeloma
Frederick L. Locke, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
Characteristics and Outcomes of Patients Who Did Not Develop CRS after Axicabtagene Ciloleucel for Relapsed/Refractory Large B-Cell Lymphoma: Results from the US Lymph...
Frederick L. Locke, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
Experience with Axicabtagene Ciloleucel (Axi-cel) in Patients with Secondary CNS Involvement: Results from the US Lymphoma CAR T Consortium
Frederick L. Locke, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
The Lymphoma Tumor Microenvironment Influences Toxicity after CD19 CAR T Cell Therapy
Frederick L. Locke, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
Characteristics and Outcomes of Patients Who Did Not Develop CRS after Axicabtagene Ciloleucel for Relapsed/Refractory Large B-Cell Lymphoma: Results from the US Lymph...
Frederick L. Locke, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
Detectable Circulating Tumor DNA 28 Days after the CD19 CAR T-Cell Therapy, Axicabtagene Ciloleucel, Is Associated with Poor Outcomes in Patients with Diffuse Large B-...
Frederick L. Locke, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Post-Marketing Use Outcomes of an Anti-CD19 Chimeric Antigen Receptor (CAR) T Cell Therapy, Axicabtagene Ciloleucel (Axi-Cel), for the Treatment of Large B Cell Lympho...
Frederick L. Locke, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
KTE-X19, an Anti-CD19 Chimeric Antigen Receptor (CAR) T Cell Therapy, in Patients (Pts) With Relapsed/Refractory (R/R) Mantle Cell Lymphoma (MCL): Results of the Phase...
Frederick L. Locke, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
Fever Characteristics Associated with Toxicity and Outcome after Anti-CD19 CAR T-Cell Therapy for Aggressive Lymphoma
Frederick L. Locke, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
CD19-Loss with Preservation of Other B Cell Lineage Features in Patients with Large B Cell Lymphoma Who Relapsed Post_Axi-Cel
Frederick L. Locke, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
Tumor Inflammation and Myeloid Derived Suppressor Cells Reduce the Efficacy of CD19 CAR T Cell Therapy in Lymphoma
Frederick L. Locke, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
CAR T-Cell Therapy in Lymphoma, Myeloma, and Leukemia _ Clinical Updates and Innovations
61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
Patient-Reported and Neurocognitive Outcomes in Patients Treated with Axicabtagene Ciloleucel
2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
Prediction of CAR T-Related Toxicities in R/R DLBCL Patients Treated with Axicabtagene Ciloleucel Using Point of Care Cytokine Measurements
2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
Axicabtagene Ciloleucel (Axi-cel) CD19 Chimeric Antigen Receptor (CAR) T-Cell Therapy for Relapsed/Refractory Large B-Cell Lymphoma: Real World ExperienceClinically Re...
2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
Outcomes by prior lines of therapy (LoT) in ZUMA-1, the pivotal phase 2 study of axicabtagene ciloleucel (Axi-Cel) in patients (Pts) with refractory large B-cell lymph...
Durability of response in ZUMA-1, the pivotal phase 2 study of axicabtagene ciloleucel (Axi-Cel) in patients (Pts) with refractory large B-cell lymphoma.
Phase 3 Study Results Show Metabolic Tumor Volume Improves Prognosis Compared to SPD in Second-Line R/R LBCLDecember 11th, 2022
Time to CAR T-cell Therapy May Impact Outcomes for Patients with Relapsed/Refractory Large B-cell Lymphoma in New CIBMTR AnalysisDecember 11th, 2022
Body of Evidence Grows from ZUMA-7 Study Supporting Initial Treatment with Kite’s Yescarta® CAR T-cell Therapy for Patients with Relapsed or Refractory Large B-cell LymphomaDecember 11th, 2022
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