GenWenMD

PubMed

• 10 citations
  Heritable influence of DBH on adrenergic and renal function: twin and disease studies.
  Dalal N. Pasha, Jason T. Davis, Fangwen Rao, Yuqing Chen, Gen Wen, Maple M. Fung, Manjula Mahata, Kuixing Zhang, Danuta Trzebinska, Maja Mustapic, C. Makena Hightower,...> ;Plos One. 2013 Dec 31
• 8 citations
  Heredity and cardiometabolic risk: naturally occurring polymorphisms in the human neuropeptide Y2 receptor promoter disrupt multiple transcriptional response motifs
  Zhiyun Wei, Kuixing Zhang, Gen Wen, Karthika Balasubramanian, Pei An B Shih, Fangwen Rao, Ryan S. Friese, Jose Pablo Miramontes-Gonzalez, Geert W. Schmid-Schoenbein, H...> ;Journal of Hypertension. 2013 Jan 1
• 5 citations
  Genetic variation within a metabolic motif in the chromogranin a promoter: pleiotropic influence on cardiometabolic risk traits in twins.
  Fangwen Rao, Stephane Chiron, Zhiyun Wei, Maple M. Fung, Yuqing Chen, Gen Wen, Srikrishna Khandrika, Michael G. Ziegler, Beben Benyamin, Grant W. Montgomery, John Whit...> ;American Journal of Hypertension. 2012 Jan 1
• 2 citations
  Proteomic analysis yields an unexpected trans-acting point in control of the human sympathochromaffin phenotype.
  Stephane Chiron, Zhiyun Wei, Yuqing Chen, Kuixing Zhang, Gen Wen, Wolfgang H. Fischer, Sushil K. Mahata, Daniel T. O'Connor> ;Circulation. Cardiovascular Genetics. 2011 Aug 1
• 16 citations
  Catecholamine Storage Vesicles: Role of Core Protein Genetic Polymorphisms in Hypertension
  Kuixing Zhang, Yuqing Chen, Gen Wen, Manjula Mahata, Fangwen Rao, Maple M. Fung, Sucheta M. Vaingankar, Nilima Biswas, Jiaur R. Gayen, Ryan S. Friese, Sushil K. Mahata...> ;Current Hypertension Reports. 2011 Feb 1
• 15 citations
  Human dopamine β-hydroxylase promoter variant alters transcription in chromaffin cells, enzyme secretion, and blood pressure.
  Yuqing Chen, Kuixing Zhang, Gen Wen, Fangwen Rao, Amber P. Sanchez, Lei Wang, Juan L. Rodriguez-Flores, Manjula Mahata, Sushil K. Mahata, Jill Waalen, Michael G. Ziegl...> ;American Journal of Hypertension. 2011 Jan 1
• 7 citations
  Naturally Occurring Genetic Variants in Human Chromogranin A (CHGA) Associated with Hypertension as well as Hypertensive Renal Disease
  Yuqing Chen, Fangwen Rao, Gen Wen, Jiaur R. Gayen, Kuixing Zhang, Sucheta M. Vaingankar, Nilima Biswas, Manjula Mahata, Ryan S. Friese, Maple M. Fung, Rany M. Salem, C...> ;Cellular and Molecular Neurobiology. 2010 Nov 9
• 6 citations
  Conserved regulatory motifs at phenylethanolamine N-methyltransferase (PNMT) are disrupted by common functional genetic variation: an integrated computational/experime...
  Juan L. Rodriguez-Flores, Kuixing Zhang, Sun Woo Kang, Gen Wen, Sajalendu Ghosh, Ryan S. Friese, Sushil K. Mahata, Shankar Subramaniam, Bruce A. Hamilton, Daniel T. O'...> ;Mammalian Genome. 2010 Mar 5
• 40 citations
  Human dopamine beta-hydroxylase (DBH) regulatory polymorphism that influences enzymatic activity, autonomic function, and blood pressure.
  Yuqing Chen, Gen Wen, Fangwen Rao, Kuixing Zhang, Lei Wang, Juan L. Rodriguez-Flores, Amber P. Sanchez, Manjula Mahata, Laurent Taupenot, Ping Sun, Sushil K. Mahata, B...> ;Journal of Hypertension. 2010 Jan 1
• Peptide YY (PYY) Gene Polymorphisms in the 3'-Untranslated Region and Proximal Promoter Regions Regulate Cellular Gene Expression and PYY Secretion and Metabolic Syndr...
  Pei-An Betty Shih, Lei Wang, Stephane Chiron, Gen Wen, Caroline Nievergelt, Manjula Mahata, Srikrishna Khandrika, Fangwen Rao, Maple M Fung, Sushil K Mahata, Bruce A H...> ;Endocrine Reviews. 2009 Dec 1
• 2 citations
  Peptide YY (PYY) gene polymorphisms in the 3'-untranslated and proximal promoter regions regulate cellular gene expression and PYY secretion and metabolic syndrome tra...
  Pei-An Betty Shih, Lei Wang, Stephane Chiron, Gen Wen, Caroline Nievergelt, Manjula Mahata, Srikrishna Khandrika, Fangwen Rao, Maple M Fung, Sushil K Mahata, Bruce A H...> ;The Journal of Clinical Endocrinology and Metabolism. 2009 Nov 1
• 11 citations
  Adrenergic Polymorphism and the Human Stress Response
  Fangwen Rao, Lian Zhang, Jennifer Wessel, Kuixing Zhang, Gen Wen, Brian P. Kennedy, Brinda K. Rana, Madhusudan Das, Juan L. Rodriguez-Flores, Douglas W. Smith, Peter E...> ;Annals of the New York Academy of Sciences. 2008 Dec 1
• 36 citations
  Naturally occurring human genetic variation in the 3'-untranslated region of the secretory protein chromogranin A is associated with autonomic blood pressure regulatio...
  Yuqing Chen, Fangwen Rao, Juan L. Rodriguez-Flores, Manjula Mahata, Maple M. Fung, Mats Stridsberg, Sucheta M. Vaingankar, Gen Wen, Rany M. Salem, Madhusudan Das, Myle...> ;Journal of the American College of Cardiology. 2008 Oct 28
• 25 citations
  Common genetic variants in the chromogranin A promoter alter autonomic activity and blood pressure.
  Yuhong Chen, Fangwen Rao, Juan L. Rodriguez-Flores, Nitish R. Mahapatra, Manjula Mahata, Gen Wen, Rany M. Salem, Pei-an Betty Shih, Madhusudan Das, Nicholas J. Schork,...> ;Kidney International. 2008 Jul 1
• 46 citations
  Chromogranin A Polymorphisms Are Associated With Hypertensive Renal Disease
  Rany M. Salem, Peter E. Cadman, Yuqing Chen, Fangwen Rao, Gen Wen, Bruce A. Hamilton, Brinda K. Rana, Douglas W. Smith, Mats Stridsberg, Harry J. Ward, Manjula Mahata,...> ;Journal of the American Society of Nephrology. 2008 Mar 1
• 77 citations
  Tyrosine hydroxylase, the rate-limiting enzyme in catecholamine biosynthesis: discovery of common human genetic variants governing transcription, autonomic activity, a...
  Fangwen Rao, Lian Zhang, Jennifer Wessel, Kuixing Zhang, Gen Wen, Brian P. Kennedy, Brinda K. Rana, Madhusudan Das, Juan L. Rodriguez-Flores, Douglas W. Smith, Peter E...> ;Circulation. 2007 Aug 28
• 23 citations
  Biogenesis of the secretory granule: chromogranin A coiled-coil structure results in unusual physical properties and suggests a mechanism for granule core condensation.
  C Mosley, Laurent Taupenot, Nilima Biswas, Joseph P. Taulane, Norman H. Olson, Sucheta M. Vaingankar, Gen Wen, Nicholas J. Schork, Michael G. Ziegler, Sushil K. Mahata...> ;Biochemistry. 2007 Sep 25
• 22 citations
  An ancestral variant of Secretogranin II confers regulation by PHOX2 transcription factors and association with hypertension
  Gen Wen, Jennifer Wessel, Weidong Zhou, Georg Ehret, Fangwen Rao, Mats Stridsberg, Sushil K. Mahata, Peter M. Gent, Madhusudan Das, Richard S. Cooper, Aravinda Chakrav...> ;Human Molecular Genetics. 2007 Jul 15
• 92 citations
  Catecholamine Release–Inhibitory Peptide Catestatin (Chromogranin A352–372) Naturally Occurring Amino Acid Variant Gly364Ser Causes Profound Changes in Human Autonomic...
  Fangwen Rao, Gen Wen, Jiaur R. Gayen, Madhusudan Das, Sucheta M. Vaingankar, Brinda K. Rana, Manjula Mahata, Brian P. Kennedy, Rany M. Salem, Mats Stridsberg, Kenneth ...> ;Circulation. 2007 May 1
• 14 citations
  Heredity of Endothelin Secretion Human Twin Studies Reveal the Influence of Polymorphism at the Chromogranin A Locus, a Novel Determinant of Endothelial Function
  Elizabeth O. Lillie, Manjula Mahata, Srikrishna Khandrika, Fangwen Rao, Richard A. Bundey, Gen Wen, Yuqing Chen, Laurent Taupenot, Douglas W. Smith, Sushil K. Mahata, ...> ;Circulation. 2007 May 1
• 37 citations
  Renal Albumin Excretion: Twin Studies Identify Influences of Heredity, Environment, and Adrenergic Pathway Polymorphism
  Fangwen Rao, Jennifer Wessel, Gen Wen, Lian Zhang, Brinda K. Rana, Brian P. Kennedy, Tiffany A. Greenwood, Rany M. Salem, Yuqing Chen, Srikrishna Khandrika, Bruce A. H...> ;Hypertension. 2007 May 1
• 86 citations
  C-reactive protein, an 'intermediate phenotype' for inflammation: Human twin studies reveal heritability, association with blood pressure and the metabolic syndrome, a...
  Jennifer Wessel, Guillermo Moratorio, Fangwen Rao, Manjula Mahata, Lian Zhang, William Greene, Brinda K. Rana, Brian P. Kennedy, Srikrishna Khandrika, Pauline Huang, E...> ;Journal of Hypertension. 2007 Feb 1
• 26 citations
  Catecholamine storage vesicles and the metabolic syndrome: the role of the chromogranin A fragment pancreastatin
  Kuixing Zhang, Fangwen Rao, Gen Wen, Rany M. Salem, Sucheta M. Vaingankar, Manjula Mahata, Nitish R. Mahapatra, Elizabeth O. Lillie, Peter E. Cadman, Ryan S. Friese, B...> ;Diabetes, Obesity & Metabolism. 2006 Nov 1
• 64 citations
  Analyses of coding region polymorphisms in apical and basolateral human organic anion transporter (OAT) genes [OAT1 (NKT), OAT2, OAT3, OAT4, URAT (RST)] Rapid Communic...
  Gang Xu, Vibha Bhatnagar, Gen Wen, Bruce A. Hamilton, Satish A. Eraly, Sanjay K. Nigam> ;Kidney International. 2005 Oct 1
• 66 citations
  Pancreastatin: Multiple Actions on Human Intermediary Metabolism in Vivo, Variation in Disease, and Naturally Occurring Functional Genetic Polymorphism
  Daniel T. O'Connor, Peter E. Cadman, Clayton Smiley, Rany M. Salem, Fangwen Rao, Joshua M. Smith, Stephen D. Funk, Sushil K. Mahata, Manjula Mahata, Gen Wen, Laurent T...> ;The Journal of Clinical Endocrinology and Metabolism. 2005 Sep 1
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