GeorgeArthurPorterJr.MD

PubMed

• 3 citations
  Neonatal hypoxic ischemic encephalopathy increases acute kidney injury urinary biomarkers in a rat model.
  Angela M Groves, Carl J Johnston, Gisela G Beutner, Jane E Dahlstrom, Mark Koina, Michael A O'Reilly, George Porter, Patrick D Brophy, Alison L Kent> ;Physiological Reports. 2022 Dec 1
• 6 citations
  Transcriptional regulation of cyclophilin D by BMP/Smad signaling and its role in osteogenic differentiation.
  Rubens Sautchuk, Brianna H Kalicharan, Katherine Escalera-Rivera, Jennifer H Jonason, George A Porter, Hani A Awad, Roman A Eliseev> ;Elife. 2022 May 30
• 17 citations
  Mechanisms of Congenital Heart Disease Caused by NAA15 Haploinsufficiency
  Tarsha Ward, Warren Tai, Sarah U. Morton, Francis Impens, Petra Van Damme, Delphi Van Haver, Evy Timmerman, Gabriela Venturini, Kehan Zhang, Min Young Jang, Jon A. L. ...> ;Circulation Research. 2021 Apr 16
• 26 citations
  Association of Damaging Variants in Genes With Increased Cancer Risk Among Patients With Congenital Heart Disease.
  Sarah U. Morton, Akiko Shimamura, Peter E. Newburger, Alexander R. Opotowsky, Daniel Quiat, Alexandre C. Pereira, Sheng Chih Jin, Michelle Gurvitz, Martina Brueckner, ...> ;JAMA Cardiology. 2021 Apr 1
• 15 citations
  Neonatal hyperoxia inhibits proliferation and survival of atrial cardiomyocytes by suppressing fatty acid synthesis.
  Ethan D. Cohen, Min Yee, George A. Porter, Erin E Ritzer, Andrew McDavid, Paul S. Brookes, Gloria S. Pryhuber, Michael A. O'Reilly> ;JCI Insight. 2021 Mar 8
• 5 citations
  Native Gel Electrophoresis and Immunoblotting to Analyze Electron Transport Chain Complexes.
  Gisela Beutner, George A. Porter> ;Methods in Molecular Biology. 2021 Jan 1
• 18 citations
  Rare genetic variation at transcription factor binding sites modulates local DNA methylation profiles.
  Alejandro Martin-Trujillo, Nihir Patel, Felix Richter, Bharati Jadhav, Paras Garg, Sarah U. Morton, David M. McKean, Steven R. DePalma, Elizabeth Goldmuntz, Dorota Gru...> ;Plos Genetics. 2020 Nov 20
• 24 citations
  GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm.
  Arun Sharma, Lauren K. Wasson, Jon A. L. Willcox, Sarah U. Morton, Joshua M. Gorham, Daniel M. DeLaughter, Meraj Neyazi, Manuel Schmid, Radhika Agarwal, Min Young Jang...> ;Elife. 2020 Oct 15
• 72 citations
  Genomic analyses implicate noncoding de novo variants in congenital heart disease.
  Felix Richter, Sarah U. Morton, Seong Won Kim, Alexander Kitaygorodsky, Lauren K. Wasson, Kathleen M. Chen, Jian Zhou, Hongjian Qi, Nihir Patel, Steven R. DePalma, Mic...> ;Nature Genetics. 2020 Aug 1
• 25 citations
  De Novo Damaging Variants, Clinical Phenotypes, and Post-Operative Outcomes in Congenital Heart Disease.
  Marko T. Boskovski, Jason Homsy, Meena Nathan, Lynn A. Sleeper, Sarah U. Morton, Kathryn B. Manheimer, Angela Tai, Joshua M. Gorham, Matthew J. Lewis, Michael F. Swart...> ;Circulation. Genomic and Precision Medicine. 2020 Jun 30
• 16 citations
  EM-mosaic detects mosaic point mutations that contribute to congenital heart disease.
  Alexander Hsieh, Sarah U. Morton, Jon A. L. Willcox, Joshua M. Gorham, Angela C. Tai, Hongjian Qi, Steven R. DePalma, David M. McKean, Emily Leann Griffin, Kathryn B. ...> ;Genome Medicine. 2020 Apr 29
• 1 citations
  A 235 Kb deletion at 17q21.33 encompassing the COL1A1, and two additional secondary copy number variants in an infant with type I osteogenesis imperfecta: A rare case ...
  Numbereye Numbere, David R. Weber, George A. Porter, Mohammed Anwar Iqbal> ;Molecular Genetics & Genomic Medicine. 2020 Apr 13
• 13 citations
  Systems Analysis Implicates WAVE2 Complex in the Pathogenesis of Developmental Left-Sided Obstructive Heart Defects
  Jonathan J. Edwards, Andrew D. Rouillard, Nicolas F. Fernandez, Zichen Wang, Alexander Lachmann, Sunita S. Shankaran, Brent W. Bisgrove, Bradley L. Demarest, Nahid Tur...> ;JACC. Basic to Translational Science. 2020 Apr 1
• 51 citations
  Mitochondrial Oxidative Phosphorylation defect in the Heart of Subjects with Coronary Artery Disease.
  Karima Ait-Aissa, Scott C. Blaszak, Gisela Beutner, Shirng-Wern Tsaih, Garrett Morgan, Janine H. Santos, Michael J. Flister, David L. Joyce, Amadou K.S. Camara, David ...> ;Scientific Reports. 2019 May 20
• 24 citations
  Dual role of inorganic polyphosphate in cardiac myocytes: The importance of polyP chain length for energy metabolism and mPTP activation.
  Lea K. Seidlmayer, María R. Gómez-García, Toshikazu Shiba, George A. Porter, Evgeny Pavlov, Donald M. Bers, Elena N. Dedkova> ;Archives of Biochemistry and Biophysics. 2019 Feb 15
• 1 citations
  Reply to ‘Double-outlet right ventricle is not hypoplastic left heart syndrome’
  Cecilia W. Lo, Xiaoqin Liu, George C. Gabriel, Lisa J. Martin, George A. Porter, D. Woodrow Benson> ;Nature Genetics. 2019 Feb 1
• 73 citations
  Cyclophilin D, Somehow a Master Regulator of Mitochondrial Function.
  George A. Porter, Gisela Beutner> ;Biomolecules. 2018 Dec 14
• 13 citations
  Potassium conservation is impaired in mice with reduced renal expression of Kir4.1
  Sundeep Malik, Emily Lambert, Junhui Zhang, Tong Wang, Heather L. Clark, Michael W. Cypress, Bruce I. Goldman, George A. Porter, Salvador Pena, Wilson Nino, Daniel A. ...> ;American Journal of Physiology. Renal Physiology. 2018 Aug 15
• 11 citations
  Metabolomics reveals critical adrenergic regulatory checkpoints in glycolysis and pentose-phosphate pathways in embryonic heart
  Jessica N. R. Peoples, Timmi Maxmillian, Quynh Le, Sergiy M. Nadtochiy, Paul S. Brookes, George A. Porter, Victor L. Davidson, Steven N. Ebert> ;The Journal of Biological Chemistry. 2018 May 4
• 71 citations
  The Congenital Heart Disease Genetic Network Study: Cohort description
  Thanh T. Hoang, Elizabeth Goldmuntz, Amy E. Roberts, Wendy K. Chung, Jennie Kline, John E. Deanfield, Alessandro Giardini, Adolfo Aleman, Bruce D. Gelb, Meghan K Mac N...> ;Plos One. 2018 Jan 19
• 20 citations
  Neonatal hyperoxia depletes pulmonary vein cardiomyocytes in adult mice via mitochondrial oxidation.
  Min Yee, Ethan D. Cohen, William Domm, George A. Porter, Andrew McDavid, Michael A. O'Reilly> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2018 Jan 18
• 56 citations
  Cyclophilin D regulates the dynamic assembly of mitochondrial ATP synthase into synthasomes.
  Gisela Beutner, Ryan E. Alanzalon, George A. Porter> ;Scientific Reports. 2017 Nov 3
• 489 citations
  Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands
  Sheng Chih Jin, Jason Homsy, Samir Zaidi, Qiongshi Lu, Sarah U. Morton, Steven R. DePalma, Xue Zeng, Hongjian Qi, Weni Chang, Michael C. Sierant, Wei Chien Hung, Shoze...> ;Nature Genetics. 2017 Oct 9
• 11 citations
  Analyzing Supercomplexes of the Mitochondrial Electron Transport Chain with Native Electrophoresis, In-gel Assays, and Electroelution.
  Gisela Beutner, George A. Porter> ;Journal of Visualized Experiments. 2017 Jun 1
• 132 citations
  The complex genetics of hypoplastic left heart syndrome
  Xiaoqin Liu, Hisato Yagi, Shazina Saeed, Abha S. Bais, George C. Gabriel, Zhaohan Chen, Kevin A. Peterson, You Li, Molly Schwartz, William T Reynolds, Manush Saydmoham...> ;Nature Genetics. 2017 May 22
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