GeraldVincentMcMahonMD

PubMed

• 15 citations
  ErbB activation signatures as potential biomarkers for anti-ErbB3 treatment in HNSCC
  Diego Alvarado, Gwenda F. Ligon, Jay S. Lillquist, Scott Seibel, Gerald J. Wallweber, Veronique Neumeister, David L. Rimm, Gerald McMahon, Theresa LaVallee> ;Plos One. 2017 Jul 19
• 19 citations
  KTN0158, a Humanized Anti-KIT Monoclonal Antibody, Demonstrates Biologic Activity against both Normal and Malignant Canine Mast Cells.
  Cheryl A. London, Heather L. Gardner, Sarah B. Rippy, G. S. Post, Krista M. D. La Perle, Linda Crew, Lori Lopresti-Morrow, Andrew J. Garton, Gerald McMahon, Theresa La...> ;Clinical Cancer Research. 2017 May 15
• 3 citations
  Antitumor Properties of an IgG2-Enhanced Next-Generation MET Monoclonal Antibody That Degrades Wild-Type and Mutant MET Receptors
  Yan Yang, Sreekala Mandiyan, Brett S. Robinson, Gerald McMahon> ;Cancer Research. 2016 Oct 1
• 4 citations
  Emerging Receptor Tyrosine Kinase Drug Targets: Implications for Antibody-Based Therapies for Oncology and Immunologic Disorders.
  Theresa LaVallee, Diego Alvarado, Andrew J. Garton, E. Sergio Trombetta, Richard Gedrich, Gerald McMahon> ;Critical Reviews in Oncogenesis. 2015 Jan 1
• Development of the first generation c-met kinase inhibitors: beginning of a path to a new treatment for cancer.
  Xueyan Wang, Gerald Mcmahon, Kenneth E. Lipson> ;Molecular Cancer Therapeutics. 2011 Nov 1
• 31 citations
  Picoplatin overcomes resistance to cell toxicity in small-cell lung cancer cells previously treated with cisplatin and carboplatin
  Chi-Hui Tang, Christi Parham, Ellyn Shocron, Gerald Mcmahon, Neela Patel> ;Cancer Chemotherapy and Pharmacology. 2011 Jun 1
• 127 citations
  PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments.
  Isabelle Tanjoni, Colin Walsh, Sean Uryu, Alok Tomar, Ju-Ock Nam, Ainhoa Mielgo, Ssang-Taek Lim, Congxin Liang, Marcel Koenig, Connie L. Sun, Neela Patel, Cheni Kwok, ...> ;Cancer Biology & Therapy. 2010 May 15
• 104 citations
  Oral delivery of PND-1186 FAK inhibitor decreases tumor growth and spontaneous breast to lung metastasis in pre-clinical models.
  Colin Walsh, Isabelle Tanjoni, Sean Uryu, Alok Tomar, Ju-Ock Nam, Hong Luo, Angelica Phillips, Neela Patel, Cheni Kwok, Gerald Mcmahon, Dwayne G. Stupack, David D. Sch...> ;Cancer Biology & Therapy. 2010 May 15
• 297 citations
  Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis
  Amir Abdollahi, Minglun Li, Gong Ping, Christian Plathow, Sophie Domhan, Fabian Kiessling, Leslie B. Lee, Gerald McMahon, Hermann Josef Gröne, Kenneth E. Lipson, Peter...> ;The Journal of Experimental Medicine. 2005 Mar 21
• 63 citations
  Troglitazone induces a rapid drop of mitochondrial membrane potential in liver HepG2 cells
  Michael P. Bova, Danny Tam, Gerald Mcmahon, Matthew N. Mattson> ;Toxicology Letters. 2005 Jan 15
• 43 citations
  The oxidative mechanism of action of ortho-quinone inhibitors of protein-tyrosine phosphatase α is mediated by hydrogen peroxide
  Michael P. Bova, Matthew N. Mattson, Stefan Vasile, Danny Tam, Leslie J. Holsinger, Meire C.D. Bremer, Terence Hui, Gerald Mcmahon, Audie Rice, Jon M. Fukuto> ;Archives of Biochemistry and Biophysics. 2004 Sep 1
• 17 citations
  Broad spectrum receptor tyrosine kinase inhibitor, SU6668, sensitizes radiation via targeting survival pathway of vascular endothelium.
  Bo Lu, Ling Geng, Amy Musiek, J. Tan, Carolyn Cao, Edwin F. Donnelly, Gerald McMahon, Hak Choy, Dennis E. Hallahan> ;International Journal of Radiation Oncology, Biology, Physics. 2004 Mar 1
• 55 citations
  SU11752 inhibits the DNA-dependent protein kinase and DNA double-strand break repair resulting in ionizing radiation sensitization
  Ismail Hassan Ismail, Susanne Mårtensson, Deborah Moshinsky, Audie Rice, Cho Tang, Anthony R. Howlett, Gerald Mcmahon, Ola Hammarsten> ;Oncogene. 2004 Jan 29
• 85 citations
  Potent and selective inhibitors of the Met [hepatocyte growth factor/scatter factor (HGF/SF) receptor] tyrosine kinase block HGF/SF-induced tumor cell growth and invas...
  Xueyan Wang, Phuong Le, Congxin Liang, Julie Chan, David Kiewlich, Todd W. Miller, Dave Harris, Li Sun, Audie Rice, Stefan Vasile, Robert A. Blake, Anthony R. Howlett,...> ;Molecular Cancer Therapeutics. 2003 Nov 1
• 24 citations
  A Selective and Oral Small Molecule Inhibitor of Vascular Epithelial Growth Factor Receptor (VEGFR)-2 and VEGFR-1 Inhibits Neovascularization and Vascular Permeability
  Neela Patel, Li Sun, Deborah Moshinsky, Hui Chen, Kathleen M. Leahy, Phuong Le, Katherine G. Moss, Xueyan Wang, Audie Rice, Danny Tam, A. Douglas Laird, Xiaoming Yu, Q...> ;The Journal of Pharmacology and Experimental Therapeutics. 2003 Sep 1
• 224 citations
  SU11248 Maintenance Therapy Prevents Tumor Regrowth after Fractionated Irradiation of Murine Tumor Models
  Aaron J. Schueneman, Eric Himmelfarb, Ling Geng, Jiahua Tan, Edwin F. Donnelly, Dirk B. Mendel, Gerald McMahon, Dennis E. Hallahan> ;Cancer Research. 2003 Jul 15
• 197 citations
  Phase I Dose-Escalating Study of SU11654, a Small Molecule Receptor Tyrosine Kinase Inhibitor, in Dogs with Spontaneous Malignancies,
  Cheryl A. London, Alison L. Hannah, Regina Zadovoskaya, May B. Chien, Cynthia Kollias-Baker, Mona P. Rosenberg, Sue Downing, G. S. Post, Joseph F. Boucher, Narmada She...> ;Clinical Cancer Research. 2003 Jul 1
• 30 citations
  Vascular endothelial growth factor (VEGF) receptor-2 signaling mediates VEGF-CΔNΔC- and VEGF-A-induced angiogenesis in vitro
  Jean-Christophe Tille, Xueyan Wang, Kenneth E. Lipson, Gerald Mcmahon, Napoleone Ferrara, Zhenping Zhu, Daniel J. Hicklin, Jonathan P. Sleeman, Ulf Eriksson, Kari Alit...> ;Experimental Cell Research. 2003 May 1
• 42 citations
  Structure-based design and discovery of novel inhibitors of protein tyrosine phosphatases.
  Ping Huang, John Ramphal, James Wei, Congxin Liang, Bahija Jallal, Gerald McMahon, Cho Tang> ;Bioorganic & Medicinal Chemistry. 2003 Apr 1
• 17 citations
  Improved effect of an antiangiogenic tyrosine kinase inhibitor (SU5416) by combinations with fractionated radiotherapy or low molecular weight heparin.
  Eva Løbner Lund, Minna W.B. Olsen, Kenneth E. Lipson, Gerald Mcmahon, Anthony R. Howlett, Paul E.G. Kristjansen> ;Neoplasia. 2003 Mar 1
• 1616 citations
  In Vivo Antitumor Activity of SU11248, a Novel Tyrosine Kinase Inhibitor Targeting Vascular Endothelial Growth Factor and Platelet-derived Growth Factor Receptors Dete...
  Dirk B. Mendel, A. Douglas Laird, Xiaohua Xin, Sharianne G. Louie, James G. Christensen, Guangmin Li, Randall E. Schreck, Tinya Abrams, Theresa J. Ngai, Leslie Lee, Le...> ;Clinical Cancer Research. 2003 Jan 1
• 77 citations
  Antiangiogenic Effect by SU5416 Is Partly Attributable to Inhibition of Flt-1 Receptor Signaling 1 Supported by grant-in-aid for Cancer Research from the Ministry of E...
  Takashi Itokawa, Hiroki Nokihara, Yasuhiko Nishioka, Saburo Sone, Yukihide Iwamoto, Yuji Yamada, Julie M. Cherrington, Gerald McMahon, Masabumi Shibuya, Michihiko Kuwa...> ;Molecular Cancer Therapeutics. 2002 Mar 1
• 33 citations
  In vivo intracellular signaling as a marker of antiangiogenic activity.
  Carmen C. Solorzano, Young Do Jung, Corazon D. Bucana, David J. McConkey, Gary E. Gallick, Gerald McMahon, Lee M. Ellis> ;Cancer Research. 2001 Oct 1
• 103 citations
  A Novel cdk2-selective Inhibitor, SU9516, Induces Apoptosis in Colon Carcinoma Cells
  Maureen E. Lane, Bo Yu, Audie Rice, Kenneth E. Lipson, Chris Liang, Li Sun, Cho Tang, Gerald McMahon, Richard G. Pestell, Scott Wadler> ;Cancer Research. 2001 Aug 15
• 29 citations
  Magnetic resonance imaging of ethyl-nitrosourea-induced rat gliomas: a model for experimental therapeutics of low-grade gliomas.
  Phillip E. Kish, Mila Blaivas, Myla Strawderman, Karin M. Muraszko, Donald A. Ross, Brian D. Ross, Gerald McMahon> ;Journal of Neuro-Oncology. 2001 Jul 1
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