
Giorgos Constantine Karakousis MD
Surgical Oncology (Other than Breast)
Assistant Professor, Surgery, Perelman School of Medicine
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3400 Civic Center BlvdPhiladelphia, PA 19104
Phone+1 215-662-2737
Fax+1 215-615-3424
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Education & Training
University of Pennsylvania Health SystemResidency, Surgery, 2001 - 2008
Perelman School of Medicine at the University of PennsylvaniaClass of 2001
Certifications & Licensure
PA State Medical License 2001 - 2026
NY State Medical License 2008 - 2011
American Board of Surgery Surgery
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 2 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2012, 2014, 2016-2017
- CMS Meaningful Use Stage 2 Certification Beacon Oncology 2014 Certified Module, Epic Systems Corporation, 2012, 2014, 2016-2017
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory - Core EMR, Epic Systems Corporation, 2012, 2014, 2016-2017
Clinical Trials
- Bio-marker Analysis Using Circulating Tumor Cells in Patients With Melanoma Start of enrollment: 2013 Nov 01
- Neoadjuvant PD-1 Blockade in Patients with Stage IIB/C Melanoma Start of enrollment: 2019 May 06
Publications & Presentations
PubMed
- Melanoma-patient-derived xenograft multi-omics resource melPDomiX maps gain- and loss-of-function alterations.Konstantinos Tsingas, Monzy Thomas, McKenna Reale, Min Xiao, Jayamanna Wickramasinghe
Cell Reports. 2026-06-23 - Comparing Resident Team Performance in Complex Surgical Oncology: A Single-Institution Cohort Study.Rachael C Acker, James E Sharpe, Shane Williams, Sarah I Landau, James Rowe
Annals of Surgical Oncology. 2026-06-14 - Topical resiquimod elicits systemic protection and improves anti-PD1 therapy in melanoma via priming of CD8+ T cells.Shujing Liu, Alain H Rook, Alexander C Huang, Amit Maity, Zhiyuan Qin
Cancer Immunology Research. 2026-06-11
Journal Articles
- Microsatellitosis in Patients with MelanomaRichard L White, Mark B Faries, Stanley P Leong, Andrew J Sinnamon, Jane L Messina, Barbara A Pockaj, Giorgos C Karakousis, Edmund K Bartlett, John T Vetto, Vernon K S..., Annals of Surgical Oncology
- Exosomal PD-L1 Contributes to Immunosuppression and Is Associated with Anti-PD-1 ResponseXiaowei Xu, Haidong Dong, Tara C Mitchell, Lynn M Schuchter, Alexander C Huang, Suzanne McGettigan, Wei Xu, Giorgos C Karakousis, Xiaoming Liu, Gordon Mills, Nature
Press Mentions
Surgical Hospital Closures Disproportionately Hit Poor and Socially Vulnerable CommunitiesOctober 3rd, 2025
Penn Medicine at the 2025 ASCO Annual MeetingMay 22nd, 2025
Penn Medicine’s Tara Miller Melanoma Center Is a Trailblazer for Skin Cancer TreatmentJune 2nd, 2022
Professional Memberships
- Member
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