
Ronald P DeMatteo MD
Surgical Oncology (Other than Breast)
Chair, Department of Surgery Penn Medicine
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3400 Civic Center BlvdPhiladelphia, PA 19104
Phone+1 215-662-2626
Fax+1 215-614-0244
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Education & Training
University of Pennsylvania Health SystemResidency, Surgery, 1990 - 1997
Weill Cornell MedicineClass of 1990
Johns Hopkins UniversityB.A., Natural Sciences, 1983 - 1986
Certifications & Licensure
PA State Medical License 1993 - 2026
NY State Medical License 1997 - 2018
American Board of Surgery Surgery
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification MyMSK, Memorial Sloan Kettering, 2016-2017
- CMS Meaningful Use Stage 1 Certification Sunrise Ambulatory Care, Allscripts, 2016-2017
- Surgical Oncology Fellows' Outstanding Teacher Award Memorial Hospital, 2017
Clinical Trials
- Imatinib Mesylate in Treating Patients With Gastrointestinal Stromal Tumor That Has Been Completely Removed During Surgery
- Portal Vein Embolization in Treating Patients With Liver Metastases From Primary Colorectal Cancer
- Sho-Saiko-To Following Removal of Liver Cancer By Embolization in Treating Patients With Liver Cancer That Cannot Be Surgically Removed
Publications & Presentations
PubMed
- Recurrence Patterns of Resected Ampullary Adenocarcinoma and Implications for Multimodal Therapy: A Hidden Genome-Derived Analysis from the Ampullary Cancer Collaborat...Brett L Ecker, Kenneth Seier, Ankur Choubey, Austin M Eckhoff, Gabriella N Tortorello
Annals of Surgical Oncology. 2026-09-18 - B7-H4 enrichment represents a site-specific immunotherapy target in small bowel gastrointestinal stromal tumors.Henry Singer, Montana Morris, Roberta Maestro, Angelo Paolo Dei Tos, Ronald P DeMatteo
Biorxiv. 2026-08-08 - Estrogen-related receptor alpha (ERRα) promotes gastrointestinal stromal tumor progression and epithelial-mesenchymal transition through Wnt/β-catenin.Ronald DeMatteo, Taylor Hartlein, Shan Zeng, Ferdinand Rossi, Montana Morris
Research Square. 2026-06-24
Journal Articles
- Quantitative Imaging Features of Pretreatment CT Predict Volumetric Response to Chemotherapy in Patients with Colorectal Liver MetastasesAndrea Cercek, William R Jarnagin, Jinru Shia, Peter J Allen, Kenneth P Seastedt, Nancy E Kemeny, Ronald P DeMatteo, Vinod P Balachandran, T Peter Kingham, European Radiology
- The cost of postoperative pancreatic fistula versus the cost of pasireotide: Results from a prospective randomized trialMa LW, Dominguez-Rosado I, Gennarelli RL, Bach PB, Gonen M, D'Angelica MI, DeMatteo RP, Kingham TP, Brennan MF, Jarnagin WR, Allen PJ, Ann Surg, 1/1/2017
- Colorectal cancer liver metastases and concurrent extrahepatic disease treated with resectionLeung U, Gonen M, Allen PJ, Kingham TP, DeMatteo RP, Jarnagin WR, D'Angelica MI, Ann Surg, 1/1/2017
Books/Book Chapters
Press Mentions
Penn Medicine Awarded $9 Million to Advance Study of Technology That Lights up Lung Cancer TumorsJune 27th, 2022
Hospitals Sustained Huge Financial Losses from Lost Revenues During COVID-19 Pandemic as Patients Lost Timely Access to Surgical ServicesOctober 23rd, 2021
Patient Advocacy and the Future of Systemic Therapies in Liver Cancer: An Interview with Ghassan Abou-AlfaMarch 31st, 2020
Grant Support
- SURGICAL ONCOLOGY RESEARCH TRAINING PROGRAM AT PENNUNIVERSITY OF PENNSYLVANIA2020–2030
- Molecular Mechanisms in Gastrointestinal Stromal TumorUNIVERSITY OF PENNSYLVANIA2004–2027
- Liver Dendritic Cells In Tolerance And ImmunityNational Institute Of Diabetes And Digestive And Kidney Diseases2004–2011
- Natural Killer Dendritic Cells In Listeria InfectionNational Institute Of Allergy And Infectious Diseases2006–2007
- STI571 Therapy For Gastrointestinal Stromal TumorsNational Cancer Institute2001–2002
Professional Memberships
- Member
- Member
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