GonzaloLLopezMDFACS

PubMed

• 12 citations
  GAS7 Deficiency Promotes Metastasis in MYCN-driven Neuroblastoma
  Zhi-Wei Dong, Kok Siong Yeo, Gonzalo Lopez, Cheng Zhang, Erin N. Dankert Eggum, Jo Lynne Rokita, Choong Yong Ung, Taylor M. Levee, Zuag Paj Her, Cassie J. Howe, Xiaona...> ;Cancer Research. 2021 Jun 1
• 123 citations
  CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapy.
  Alba Rodriguez-Garcia, Rachel C. Lynn, Mathilde Poussin, Monika A. Eiva, Lauren C. Shaw, Roddy S. O’Connor, Nicholas G. Minutolo, Victoria Casado-Medrano, Gonzalo Lope...> ;Nature Communications. 2021 Feb 9
• 140 citations
  Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer
  Francesca Petralia, Nicole Tignor, Boris Reva, Mateusz Koptyra, Shrabanti Chowdhury, Dmitry Rykunov, Azra Krek, Weiping Ma, Yuankun Zhu, Jiayi Ji, Anna Calinawan, Jeff...> ;Cell. 2020 Dec 23
• 9 citations
  svpluscnv: analysis and visualization of complex structural variation data.
  Gonzalo Lopez, Laura E. Egolf, Federico M. Giorgi, Sharon J. Diskin, Adam A Margolin> ;Bioinformatics. 2021 Jul 27
• 13 citations
  Somatic structural variation targets neurodevelopmental genes and identifies SHANK2 as a tumor suppressor in neuroblastoma.
  Gonzalo Lopez, Karina L. Conkrite, Miriam Doepner, Komal S. Rathi, Apexa Modi, Zalman Vaksman, Lance M. Farra, Eric Hyson, Moataz Noureddine, Jun Wei, Malcolm A. Smith...> ;Genome Research. 2020 Aug 13
• 45 citations
  Telomere maintenance mechanisms define clinical outcome in high-risk neuroblastoma
  Balakrishna Koneru, Gonzalo Lopez, Ahsan Farooqi, Karina L. Conkrite, Thinh H. Nguyen, Shawn J. Macha, Apexa Modi, Jo Lynne Rokita, Eduardo Urias, Ashly Hindle, Heathe...> ;Cancer Research. 2020 Jun 15
• 22 citations
  Pediatric high-grade glioma resources from the Children's Brain Tumor Tissue Consortium
  Heba Ijaz, Mateusz Koptyra, Krutika S. Gaonkar, Jo Lynne Rokita, Valerie Baubet, Lamiya Tauhid, Yuankun Zhu, Miguel A. Brown, Gonzalo Lopez, Bo Zhang, Sharon J. Diskin...> ;Neuro-Oncology. 2020 Jan 11
• 18 citations
  Role of Tau Protein in Remodeling of Circadian Neuronal Circuits and Sleep.
  Mercedes Arnés, Maria E. Alaniz, Caline S. Karam, Joshua D. Cho, Gonzalo Lopez, Jonathan A. Javitch, Ismael Santa-Maria> ;Frontiers in Aging Neuroscience. 2019 Nov 21
• 89 citations
  Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design.
  Jo Lynne Rokita, Komal S. Rathi, Maria F. Cardenas, Kristen A. Upton, Joy Jayaseelan, Katherine L. Cross, Jacob Pfeil, Laura E. Egolf, Gregory P. Way, Alvin Farrel, Na...> ;Cell Reports. 2019 Nov 5
• 22 citations
  Germline 16p11.2 Microdeletion Predisposes to Neuroblastoma.
  Laura E. Egolf, Zalman Vaksman, Gonzalo Lopez, Jo Lynne Rokita, Apexa Modi, Patricia V. Basta, Hakon Hakonarson, Andrew F. Olshan, Sharon J. Diskin> ;American Journal of Human Genetics. 2019 Sep 5
• 17 citations
  Transcription factor activating protein 4 is synthetically lethal and a master regulator of MYCN-amplified neuroblastoma.
  Shuobo Boboila, Gonzalo Lopez, Jiyang Yu, Debarshi Banerjee, Angela Kadenhe-Chiweshe, Eileen P. Connolly, Jessica J. Kandel, Presha Rajbhandari, Jose M. Silva, Andrea ...> ;Oncogene. 2018 Jun 7
• 82 citations
  Cross-Cohort Analysis Identifies a TEAD4-MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma.
  Presha Rajbhandari, Gonzalo Lopez, Claudia Capdevila, Beatrice Salvatori, Jiyang Yu, Ruth Rodriguez-Barrueco, Daniel Martinez, Mark Yarmarkovich, Nina Weichert-Leahey,...> ;Cancer Discovery. 2018 Jan 1
• 62 citations
  LMO1 Synergizes with MYCN to Promote Neuroblastoma Initiation and Metastasis
  Shizhen Zhu, Xiaoling Zhang, Nina Weichert-Leahey, Zhi-Wei Dong, Cheng Zhang, Gonzalo Lopez, Ting Tao, Shuning He, Andrew C. Wood, Derek A. Oldridge, Choong Yong Ung, ...> ;Cancer Cell. 2017 Sep 11
• 122 citations
  Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma.
  Kristopher R. Bosse, Pichai Raman, Zhongyu Zhu, Maria Lane, Daniel Martinez, Sabine Heitzeneder, Komal S. Rathi, Nathan M. Kendsersky, Michael Randall, Laura K. Donova...> ;Cancer Cell. 2017 Sep 11
• 83 citations
  11q deletion in neuroblastoma: a review of biological and clinical implications
  Vid Mlakar, Simona Jurkovic Mlakar, Gonzalo Lopez, John M. Maris, Marc Ansari, Fabienne Gumy-Pause> ;Molecular Cancer. 2017 Jun 29
• 138 citations
  HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma
  Omid Tavana, Dawei Li, Chao Dai, Gonzalo Lopez, Debarshi Banerjee, Ning Kon, Chao Chen, Andrea Califano, Darrell J. Yamashiro, Hongbin Sun, Wei Gu> ;Nature Medicine. 2016 Oct 1
• Correction: Inferring Protein Modulation from Gene Expression Data Using Conditional Mutual Information
  Federico M. Giorgi, Gonzalo Lopez, Jung Hoon Woo, Brygida Bisikirska, Andrea Califano, Mukesh Bansal> ;Plos One. 2016 Sep 15
• 186 citations
  ARACNe-AP: gene network reverse engineering through adaptive partitioning inference of mutual information
  Alexander Lachmann, Federico M. Giorgi, Gonzalo Lopez, Andrea Califano> ;Bioinformatics. 2016 Jul 15
• 38 citations
  HDAC8, A Potential Therapeutic Target for the Treatment of Malignant Peripheral Nerve Sheath Tumors (MPNST)
  Gonzalo Lopez, Kate Lynn J. Bill, Hemant K. Bid, Danielle Braggio, Dylan Constantino, Bethany C. Prudner, Kara Batte, Dina Lev, Raphael E. Pollock> ;Plos One. 2015 Jul 22
• 221 citations
  Elucidating Compound Mechanism of Action by Network Perturbation Analysis
  Jung Hoon Woo, Yishai Shimoni, Wan Seok Yang, Prem S. Subramaniam, Archana Iyer, Paola Nicoletti, María Rodríguez Martínez, Gonzalo Lopez, Michela Mattioli, Ronald Rea...> ;Cell. 2015 Jul 16
• 14 citations
  Inferring protein modulation from gene expression data using conditional mutual information.
  Federico M. Giorgi, Gonzalo Lopez, Jung Hoon Woo, Brygida Bisikirska, Andrea Califano, Mukesh Bansal> ;Plos One. 2014 Oct 14
• 16 citations
  FireDB: a compendium of biological and pharmacologically relevant ligands
  Paolo Maietta, Gonzalo Lopez, Angel Carro, Benjamin J. Pingilley, Leticia G. Leon, Alfonso Valencia, Michael L. Tress> ;Nucleic Acids Research. 2014 Jan 1
• 145 citations
  APPRIS: annotation of principal and alternative splice isoforms
  Jose Manuel Rodriguez, Paolo Maietta, Iakes Ezkurdia, Alessandro Pietrelli, Jan-Jaap Wesselink, Gonzalo Lopez, Alfonso Valencia, Michael L. Tress> ;Nucleic Acids Research. 2013 Jan 1
• 43 citations
  firestar—advances in the prediction of functionally important residues
  Gonzalo Lopez, Paolo Maietta, Jose Manuel Rodriguez, Alfonso Valencia, Michael L. Tress> ;Nucleic Acids Research. 2011 Jul 1
• 6 citations
  FragKB: structural and literature annotation resource of conserved peptide fragments and residues.
  Ashish V. Tendulkar, Martin Krallinger, Victor De La Torre, Gonzalo Lopez, Pramod P. Wangikar, Alfonso Valencia> ;Plos One. 2010 Mar 18
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