GregoryAlanDeyeMD

PubMed

• 1 citations
  A Risk Profile Using Simple Hematologic Parameters to Assess Benefits From Baricitinib in Patients Hospitalized With COVID-19: A Post Hoc Analysis of the Adaptive COVI...
  Catharine I Paules, Jing Wang, Kay M Tomashek, Tyler Bonnett, Kanal Singh, Vincent C Marconi, Richard T Davey Jr, David C Lye, Lori E Dodd, Otto O Yang, Constance A Be...> ;Annals of Internal Medicine. 2024 Mar 1
• Recombinant full-length Plasmodium falciparum circumsporozoite protein-based vaccine adjuvanted with GLA-LSQ: Results of Phase 1 testing with malaria challenge.
  DeAnna J Friedman-Klabanoff, Andrea A Berry, Mark A Travassos, Mallory Shriver, Catherine Cox, Jessica Butts, Jordan S Lundeen, Kathleen A Strauss, Sudhaunshu Joshi, B...> ;The Journal of Infectious Diseases. 2024 Feb 8
• Can incorporating genotyping data into efficacy estimators improve efficiency of early phase malaria vaccine trials?
  Gail E Potter, Viviane Callier, Sudhaunshu Joshi, Ankit Dwivedi, Joana C Silva, Matthew B Laurens, Dean A Follmann, Gregory A Deye, Biraj Shrestha> ;Malaria Journal. 2023 Dec 19
• 2 citations
  Temporal Improvements in COVID-19 Outcomes for Hospitalized Adults: A Post Hoc Observational Study of Remdesivir Group Participants in the Adaptive COVID-19 Treatment ...
  Gail E Potter, Tyler Bonnett, Kevin Rubenstein, David A Lindholm, Rekha R Rapaka, Sarah B Doernberg, David C Lye, Richard A Mularski, Noreen A Hynes, Susan Kline, Cath...> ;Annals of Internal Medicine. 2022 Dec 1
• 14 citations
  PfSPZ-CVac malaria vaccine demonstrates safety among malaria-experienced adults: A randomized, controlled phase 1 trial.
  Drissa Coulibaly, Abdoulaye K Kone, Karim Traore, Amadou Niangaly, Bourema Kouriba, Charles Arama, Amatigue Zeguime, Amagana Dolo, Kirsten E Lyke, Christopher V Plowe,...> ;Eclinicalmedicine. 2022 Oct 1
• 22 citations
  A genetically engineeredparasite vaccine provides protection from controlled human malaria infection.
  Sean C Murphy, Ashley M Vaughan, James G Kublin, Matthew Fishbauger, Annette M Seilie, Kurtis P Cruz, Tracie Mankowski, Melike Firat, Sara Magee, Will Betz, Heather Ka...> ;Science Translational Medicine. 2022 Aug 24
• 2 citations
  Adverse Reactions in a Phase 1 Trial of the Anti-Malarial DM1157: An Example of Pharmacokinetic Modeling and Simulation Guiding Clinical Trial Decisions.
  Stephen J Balevic, Shruti M Raja, Rachel Randell, Gregory A Deye, Thomas Conrad, Aya Nakamura, David H Peyton, Sandra Shotwell, Katherine Liebman, Michael Cohen-Wolkow...> ;Infectious Diseases and Therapy. 2022 Apr 1
• 3 citations
  EVITA Dengue: a cluster-randomized controlled trial to EValuate the efficacy of Wolbachia-InfecTed Aedes aegypti mosquitoes in reducing the incidence of Arboviral infe...
  Matthew H Collins, Gail E Potter, Matt D T Hitchings, Ellie Butler, Michelle Wiles, Jessie K Kennedy, Sofia B Pinto, Adla B M Teixeira, Arnau Casanovas-Massana, Nadine...> ;Trials. 2022 Mar 2
• 1 citations
  Population pharmacokinetic-pharmacodynamic model of oxfendazole in healthy adults in a multiple ascending dose and food effect study and target attainment analysis
  Thanh Bach, Gregory A. Deye, Ellen E. Codd, John R. Horton, Patricia L. Winokur, Guohua An> ;Antimicrobial Agents and Chemotherapy. 2021 Oct 4
• 29 citations
  PfSPZ-CVac efficacy against malaria increases from 0% to 75% when administered in the absence of erythrocyte stage parasitemia: A randomized, placebo-controlled trial ...
  Sean C. Murphy, Gregory A. Deye, B. Kim Lee Sim, Shirley Galbiati, Jessie K. Kennedy, Kristen W. Cohen, Sumana Chakravarty, Natasha Kc, Yonas Abebe, Eric R. James, Jam...> ;Plos Pathogens. 2021 May 28
• 3 citations
  Population Pharmacokinetic Model of Oxfendazole and Metabolites in Healthy Adults following Single Ascending Doses.
  Thanh Bach, Daryl J. Murry, Larissa V. Stebounova, Gregory A. Deye, Patricia L. Winokur, Guohua An> ;Antimicrobial Agents and Chemotherapy. 2021 Mar 18
• 14 citations
  Low dose recombinant full-length circumsporozoite protein-based Plasmodium falciparum vaccine is well-tolerated and highly immunogenic in phase 1 first-in-human clinic...
  DeAnna J Friedman-Klabanoff, Andrea A. Berry, Mark A. Travassos, Catherine Cox, Yingjun Zhou, Annie X. Mo, Effie Y.H. Nomicos, Gregory A. Deye, Marcela F. Pasetti, Mat...> ;Vaccine. 2021 Jan 22
• 11 citations
  Pharmacokinetics, Safety, and Tolerability of Oxfendazole in Healthy Adults in an Open-Label Phase 1 Multiple Ascending Dose and Food Effect Study.
  Thanh Bach, Shirley Galbiati, Jessie K. Kennedy, Gregory A. Deye, Effie Y.H. Nomicos, Ellen E. Codd, Hector H. Garcia, John R. Horton, Robert H. Gilman, Armando E. Gon...> ;Antimicrobial Agents and Chemotherapy. 2020 Oct 20
• 15 citations
  Dose-Dependent Infectivity of Aseptic, Purified, Cryopreserved Plasmodium falciparum 7G8 Sporozoites in Malaria-Naive Adults.
  Matthew B. Laurens, Andrea A. Berry, Mark A. Travassos, Kathy A. Strauss, Matthew Adams, Biraj Shrestha, Tao Li, Abraham G. Eappen, Anita Manoj, Yonas Abebe, Tooba Mur...> ;The Journal of Infectious Diseases. 2019 Nov 6
• 28 citations
  A phase 1 study of the safety, reactogenicity, and immunogenicity of a Schistosoma mansoni vaccine with or without glucopyranosyl lipid A aqueous formulation (GLA-AF) ...
  Wendy A. Keitel, G.E. Potter, David Diemert, Jeffrey M. Bethony, H. M. El Sahly, J.K. Kennedy, Shital M. Patel, Jordan L. Plieskatt, W. Jones, Gregory A. Deye, Maria E...> ;Vaccine. 2019 Oct 8
• 17 citations
  Phase Ib Trial To Evaluate the Safety and Pharmacokinetics of Multiple Ascending Doses of Filociclovir (MBX-400, Cyclopropavir) in Healthy Volunteers.
  Nadine Rouphael, Selwyn J. Hurwitz, Mari Hart, Allison Beck, Evan J. Anderson, Gregory A. Deye, Blaire L. Osborn, Shu Yi Cai, Chris Focht, Cyrille Amegashie, Terry L. ...> ;Antimicrobial Agents and Chemotherapy. 2019 Aug 23
• 20 citations
  Pharmacokinetics, Safety, and Tolerability of Oxfendazole in Healthy Volunteers: a Randomized, Placebo-Controlled First-in-Human Single-Dose Escalation Study.
  Guohua An, Daryl J. Murry, Kiran Gajurel, Thanh Bach, Greg Deye, Larissa V. Stebounova, Ellen E. Codd, John R. Horton, Armando E. Gonzalez, Hector H. Garcia, Dilek Inc...> ;Antimicrobial Agents and Chemotherapy. 2019 Mar 27
• 65 citations
  Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds
  Sean R. Marcsisin, Jason C. Sousa, Gregory A. Reichard, Diana Caridha, Qiang Zeng, Norma Roncal, Ronan McNulty, Julio Careagabarja, Richard J. Sciotti, Jason W. Bennet...> ;Malaria Journal. 2014 Jan 3
• 8 citations
  Primaquine for Prophylaxis of Malaria: Has the CYP Sailed?
  Gregory A. Deye, Alan J. Magill> ;Journal of Travel Medicine. 2014 Jan 1
• 175 citations
  Primaquine Failure and Cytochrome P-450 2D6 in Plasmodium vivax Malaria
  Jason W. Bennett, Brandon S. Pybus, Anjali Yadava, Donna Tosh, Jason C. Sousa, William F. McCarthy, Gregory Deye, Victor Melendez, Christian F. Ockenhouse> ;The New England Journal of Medicine. 2013 Oct 2
• 131 citations
  The metabolism of primaquine to its active metabolite is dependent on CYP 2D6
  Brandon S. Pybus, Sean R. Marcsisin, Xiannu Jin, Gregory J. Deye, Jason C. Sousa, Qigui Li, Diana Caridha, Qiang-Xing Zeng, Gregory A. Reichard, Christian F. Ockenhous...> ;Malaria Journal. 2013 Jun 20
• 34 citations
  Use of a Rhesus Plasmodium cynomolgi Model to Screen for Anti-Hypnozoite Activity of Pharmaceutical Substances
  Gregory Deye, Montip Gettayacamin, Pranee Hansukjariya, Rawiwan Imerbsin, Jetsumon Sattabongkot, Yarrow Rothstein, Louis R. Macareo, Susan Fracisco, Kent Bennett, Alan...> ;The American Journal of Tropical Medicine and Hygiene. 2012 Jun 1
• 28 citations
  Prolonged Protection Provided by a Single Dose of Atovaquone-Proguanil for the Chemoprophylaxis of Plasmodium falciparum Malaria in a Human Challenge Model
  Gregory Deye, R. Scott Miller, Lori Miller, Carola J. Salas, Donna Tosh, Louis R. Macareo, Bryan Smith, Susan Fracisco, Emily G. Clemens, Jittawadee Murphy, Jason C. S...> ;Clinical Infectious Diseases. 2012 Jan 15
• 21 citations
  Emergent 2009 influenza A(H1N1) viruses containing HA D222N mutation associated with severe clinical outcomes in the Americas.
  Huo-Shu H. Houng, Jason Garner, Yanfei Zhou, Arthur Lyons, Robert A. Kuschner, Gregory Deye, Kristina St. Clair, Richard W. Douce, Wilson Chicaiza, Patrick J. Blair, C...> ;Journal of Clinical Virology. 2012 Jan 1
• 3 citations
  Plasmodium falciparum Infection during Suppressive Prophylaxis with Mefloquine Does Not Induce an Antibody Response to Merozoite Surface Protein-1(42)
  James E. Moon, Gregory Deye, Lori Miller, Susan Fracisco, R. Scott Miller, Donna Tosh, James F. Cummings, Colin Ohrt, Alan J. Magill> ;The American Journal of Tropical Medicine and Hygiene. 2011 May 5
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