GregoryDLongmoreMD

Hematology • Saint Louis, MO

Professor, Internal Medicine, Washington University School of Medicine

Join to view full profile

Are you Dr. Longmore?

Join over one million U.S. Physicians, Nurse Practitioners and PAs, already on Doximity.

Connect with colleagues in the same hospital or clinic
You already have 40 invites waiting!
Search all U.S. specialist profiles and refer a patient
Read the latest clinical news and earn CME/CEU credits

Claim this profile

Not you? Find your profile

Office
4921 Parkview Pl
7th Floor
Saint Louis, MO 63110
Phone+1 314-747-1171

Fax+1 314-362-3192
Is this information wrong?

Summary

Dr. Gregory Longmore, MD is a hematologist in Saint Louis, Missouri. He is currently licensed to practice medicine in Missouri. He is a Professor at Washington University School of Medicine.

Education & Training

Brigham and Women's Hospital/Massachusetts General Hospital/Dana-Farber Cancer InstituteFellowship, Hematology and Medical Oncology, 1987 - 1990
Beth Israel Deaconess Medical CenterResidency, Internal Medicine, 1983 - 1987
McGill University Faculty of MedicineClass of 1983

Certifications & Licensure

MO State Medical License 1993 - 2025
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

Elected Member The American Society for Clinical Investigation, 2000

Publications & Presentations

PubMed

Functional analysis of recurrent CDC20 promoter variants in human melanoma.
Paula M Godoy, Abimbola Oyedeji, Jacqueline L Mudd, Vasilios A Morikis, Anna P Zarov, Gregory D Longmore, Ryan C Fields, Charles K Kaufman> ;Communications Biology. 2023 Nov 29
11 citations
DDR2 Expression in Cancer-Associated Fibroblasts Promotes Ovarian Cancer Tumor Invasion and Metastasis through Periostin-ITGB1.
Favour A Akinjiyan, Ritu M Dave, Emily Alpert, Gregory D Longmore, Katherine C Fuh> ;Cancers. 2022 Jul 18
1 citations
Bacteria in tumors "hit the road" together.
Gregory D Longmore> ;Cell. 2022 Apr 14
2 citations
Collagen Linearization within Tumors.
Craig E. Barcus, Gregory D. Longmore> ;Cancer Research. 2021 Nov 15
9 citations
Author Correction: Guidelines and definitions for research on epithelial-mesenchymal transition.
Jing Yang, Parker B. Antin, Geert Berx, Cédric Blanpain, Thomas Brabletz, Marianne E. Bronner, Kyra Campbell, Amparo Cano, Jordi Casanova, Gerhard Christofori, Shoukat...> ;Nature Reviews. Molecular Cell Biology. 2021 Oct 15
7 citations
Tyrosine kinase-independent actions of DDR2 in tumor cells and cancer-associated fibroblasts influence tumor invasion, migration and metastasis.
Craig E. Barcus, Priscilla Y. Hwang, Vasilios Morikis, Audrey Brenot, Patrick Pence, Maria Clarke, Gregory D. Longmore> ;Journal of Cell Science. 2021 Oct 1
18 citations
Contextual cues from cancer cells govern cancer-associated fibroblast heterogeneity.
Neus Bota-Rabassedas, Priyam Banerjee, Yichi Niu, Wenjian Cao, Jiayi Luo, Yuanxin Xi, Xiaochao Tan, Kuanwei Sheng, Young Ho Ahn, Sieun Lee, Edwin R. Parra, Jaime Rodri...> ;Cell Reports. 2021 Apr 20
16 citations
Micro-strains in the extracellular matrix induce angiogenesis.
M. K. Sewell-Loftin, Joshua B. Katz, Steven C. George, Gregory D. Longmore> ;Lab on a Chip. 2020 Jul 28
972 citations
Guidelines and definitions for research on epithelial–mesenchymal transition
Jing Yang, Parker B. Antin, Geert Berx, Cédric Blanpain, Thomas Brabletz, Marianne E. Bronner, Kyra Campbell, Amparo Cano, Jordi Casanova, Gerhard Christofori, Shoukat...> ;Nature Reviews. Molecular Cell Biology. 2020 Jun 1
55 citations
DDR2 controls breast tumor stiffness and metastasis by regulating integrin mediated mechanotransduction in CAFs.
Samantha Van Hove Bayer, Whitney R. Grither, Audrey Brenot, Priscilla Y. Hwang, Craig E. Barcus, Melanie Ernst, Patrick Pence, Christopher Walter, Amit Pathak, Gregory...> ;Elife. 2019 May 30
2 citations
Correction: Mechanical signals regulate and activate SNAIL1 protein to control the fibrogenic response of cancer-associated fibroblasts (doi:10.1242/jcs.180539).
Kun Zhang, Whitney R. Grither, Samantha Van Hove, Hirak Biswas, Suzanne M. Ponik, Kevin W. Eliceiri, Patricia J. Keely, Gregory D. Longmore> ;Journal of Cell Science. 2019 May 1
35 citations
Randomly Distributed K14+ Breast Tumor Cells Polarize to the Leading Edge and Guide Collective Migration in Response to Chemical and Mechanical Environmental Cues.
Priscilla Y. Hwang, Audrey Brenot, Ashley C. King, Gregory D. Longmore, Steven C. George> ;Cancer Research. 2019 Apr 15
8 citations
LATS1/2 kinases trigger self-renewal of cancer stem cells in aggressive oral cancer.
Masami Nozaki, Norikazu Yabuta, Moe Fukuzawa, Satomi Mukai, Ayumi Okamoto, Towa Sasakura, Kohshiro Fukushima, Yoko Naito, Gregory D. Longmore, Hiroshi Nojima> ;Oncotarget. 2019 Feb 1
69 citations
Inhibition of tumor-microenvironment interaction and tumor invasion by small-molecule allosteric inhibitor of DDR2 extracellular domain.
Whitney R. Grither, Gregory D. Longmore> ;Proceedings of the National Academy of Sciences of the United States of America. 2018 Jul 30
37 citations
SNAIL1 action in tumor cells influences macrophage polarization and metastasis in breast cancer through altered GM-CSF secretion
Audrey Brenot, Brett L. Knolhoff, David G. DeNardo, Gregory D. Longmore> ;Oncogenesis. 2018 Mar 29
37 citations
TWIST1 induces expression of discoidin domain receptor 2 to promote ovarian cancer metastasis.
Whitney R. Grither, Laura M. Divine, E.H. Meller, Daniel Wilke, Riva A. Desai, Andrew J. Loza, Peinan Zhao, A. Lohrey, Gregory D. Longmore, Katherine Fuh> ;Oncogene. 2018 Jan 19
84 citations
Past matrix stiffness primes epithelial cells and regulates their future collective migration through a mechanical memory.
Samila Nasrollahi, Christopher Walter, Andrew J. Loza, Gregory V. Schimizzi, Gregory D. Longmore, Amit Pathak> ;Biomaterials. 2017 Nov 1
73 citations
Cancer-associated fibroblasts support vascular growth through mechanical force.
M. K. Sewell-Loftin, Samantha Van Hove Bayer, Elizabeth Crist, Taylor Hughes, Sofia M. Joison, Gregory D. Longmore, Steven C. George> ;Scientific Reports. 2017 Oct 3
228 citations
Upholding a role for EMT in breast cancer metastasis
Xin Ye, Thomas Brabletz, Yibin Kang, Gregory D. Longmore, M. Angela Nieto, Ben Z. Stanger, Jing Yang, Robert A. Weinberg> ;Nature. 2017 Jul 5
45 citations
AJUBA LIM Proteins Limit Hippo Activity in Proliferating Cells by Sequestering the Hippo Core Kinase Complex in the Cytosol
Radhika Jagannathan, Gregory V. Schimizzi, Kun Zhang, Andrew J. Loza, Norikazu Yabuta, Hitoshi Nojima, Gregory D. Longmore> ;Molecular and Cellular Biology. 2016 Oct 15
19 citations
Action of SNAIL1 in Cardiac Myofibroblasts Is Important for Cardiac Fibrosis following Hypoxic Injury
Hirak Biswas, Gregory D. Longmore> ;Plos One. 2016 Oct 5
22 citations
Cell density and actomyosin contractility control the organization of migrating collectives within an epithelium
Andrew J. Loza, Sarita Koride, Gregory V. Schimizzi, Bo Li, Sean X. Sun, Gregory D. Longmore> ;Molecular Biology of the Cell. 2016 Sep 7
6 citations
Disruption of the Cdc42/Par6/aPKC or Dlg/Scrib/Lgl Polarity Complex Promotes Epithelial Proliferation via Overlapping Mechanisms.
Gregory V. Schimizzi, Meghan T. Maher, Andrew J. Loza, Gregory D. Longmore> ;Plos One. 2016 Jul 25
71 citations
The Action of Discoidin Domain Receptor 2 in Basal Tumor Cells and Stromal Cancer-Associated Fibroblasts Is Critical for Breast Cancer Metastasis
Callie Ann S. Corsa, Audrey Brenot, Whitney R. Grither, Samantha Van Hove, Andrew J. Loza, Kun Zhang, Suzanne M. Ponik, Yuming Liu, David G. DeNardo, Kevin W. Eliceiri...> ;Cell Reports. 2016 Jun 14
262 citations
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis
Megan K. Ruhland, Andrew J. Loza, Aude Helene Capietto, Xianmin Luo, Brett L. Knolhoff, Kevin C. Flanagan, Brian A. Belt, Elise Alspach, Kathleen M. Leahy, Jingqin Luo...> ;Nature Communications. 2016 Jun 8
Join now to see all

Grant Support

Epithelial Morphogenesis In Development And DiseaseNational Institute Of General Medical Sciences2011
The Role Of Ajuba LIM Protein In Epithelia BiogenesisNational Institute Of General Medical Sciences2007–2010
The Role Of LIM Proteins In Cell Migration And AdhesionNational Cancer Institute2006–2009
Cancer Cell Invasion And MetastasisNational Cancer Institute2005–2006
Role Of LIM Proteins In Regulating Cell GrowthNational Cancer Institute2000–2004
Regulation Of Red Cell DevelopmentNational Cancer Institute1998–2000
Regulation Of Red Cell Development And LeukemogenesisNational Cancer Institute1997