
Gregory Edward Supple MD FACC, FHRS
Cardiac Electrophysiology
Associate Professor of Clinical Medicine. Director, Electrophysiology Fellowship Program, University of Pennsylvania Perelman School of Medicine
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3400 Civic Center BlvdPhiladelphia, PA 19104
Phone+1 215-615-3811
Fax+1 215-615-5235
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Summary
- Dr. Gregory Supple is a cardiologist based in Philadelphia, PA, specializing in cardiac electrophysiology. He completed his medical degree at the Perelman School of Medicine at the University of Pennsylvania, followed by an internship and residency in internal medicine at Massachusetts General Hospital. He pursued fellowships in cardiovascular disease and clinical cardiac electrophysiology at the University of Pennsylvania Health System. Dr. Supple is currently the Director of the Cardiac Electrophysiology Fellowship Program at the Hospital of the University of Pennsylvania. His expertise includes managing conditions such as Wolff-Parkinson-White syndrome, atrial fibrillation, ventricular tachycardia, and syncope. He has contributed to several publications in noted journals like JACC and Heart Rhythm and is involved in clinical trials on ventricular arrhythmia and atrial fibrillation. Dr. Supple holds fellowships with the Heart Rhythm Society and the American College of Cardiology, and he is a member of Alpha Omega Alpha and Phi Beta Kappa honor societies.
Education & Training
- University of Pennsylvania Health SystemFellowship, Clinical Cardiac Electrophysiology, 2010 - 2012
- University of Pennsylvania Health SystemFellowship, Cardiovascular Disease, 2008 - 2011
- Mass General Brigham/Massachusetts General HospitalResidency, Internal Medicine, 2006 - 2008
- Mass General Brigham/Massachusetts General HospitalInternship, Internal Medicine, 2005 - 2006
- Perelman School of Medicine at the University of PennsylvaniaClass of 2005
- Wesleyan UniversityBA, Chemistry, 1996 - 2000
Certifications & Licensure
- PA State Medical License 2008 - 2026
- MA State Medical License 2007 - 2010
- American Board of Internal Medicine Clinical Cardiac Electrophysiology
Awards, Honors, & Recognition
- Fellow (FHRS) Heart Rhythm Society, 2015
- Fellow (FACC) American College of Cardiology
- Member Alpha Omega Alpha Honor Medical Society, 2005
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Clinical Trials
- Clinical Evaluation of the Blazer Open-Irrigated Ablation Catheter for the Treatment of Paroxysmal Atrial Fibrillation Start of enrollment: 2012 Oct 01
- The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients Start of enrollment: 2022 May 27
Publications & Presentations
PubMed
- Coronary Venous Ethanol Infusion for Treatment of Refractory Ventricular Arrhythmias.Tarek Zghaib, Andres Enriquez, Robert D Schaller, Sanjay Dixit, Gregory E Supple
Heart Rhythm. 2025-04-27 - Stepwise Anatomical Approach to Ablation of Intramural Outflow Tract Ventricular Arrhythmias Guided by Septal Coronary Venous Mapping.Andres Enriquez, Haran Yogasundaram, Victor Neira, Gustavo Guandalini, Timothy Markman
Circulation. 2025-04-26 - Epicardial ventricular arrhythmia ablation: a clinical consensus statement of the European Heart Rhythm Association of the European Society of Cardiology and the Heart...Arash Arya, Luigi Di Biase, Victor Bazán, Antonio Berruezo, Andrea d'Avila
Europace. 2025-03-28
Journal Articles
- P‐Wave Morphology and Multipolar Intracardiac Atrial Activation to Facilitate Non‐Pulmonary Vein Trigger LocalizationSanjay Dixit, Francis E Marchlinski, David S Frankel, Pasquale Santangeli, Erica S Zado, Gregory E Supple, Cory M Tschabrunn, David Lin, Journal of Cardiovascular Electrophysiology
- Epicardial Ventricular Tachycardia in Ischemic Cardiomyopathy: Prevalence, Electrophysiological Characteristics, and Long‐Term Ablation OutcomesFermin C Garcia, Gregory E Supple, Andres Enriquez, Jeffrey Arkles, Pasquale Santangeli, Robert D Schaller, Francis E Marchlinski, Sanjay Dixit, David Lin, Erica S Zad..., Journal of Cardiovascular Electrophysiology
- Lead I R‐Wave Amplitude to Differentiate Idiopathic Ventricular Arrhythmias with Left Bundle Branch Block Right Inferior Axis Originating from the Left Versus Right Ve...Francis E Marchlinski, Sanjay Dixit, David S Frankel, Gregory E Supple, Fermin C Garcia, Pasquale Santangeli, David Lin, Robert D Schaller, David J Callans, Erica S Zado, Journal of Cardiovascular Electrophysiology
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Books/Book Chapters
Abstracts/Posters
- Long term Outcome of Patients with Only Non Pulmonary Vein Trigger Ablation for Atrial Fibrillation.Kondapalli L, Zado ES, Gaztanaga L, Supple GE, Deyell MW, Dahu M, Marchlinski FE., Heart Rhythm 2012, PO06-57
- ECG Differentiation Of Ventricular Arrhythmias Arising From The Left Posterior Fascicle And Postero-medial Papillary Muscle.Deyell MW, Man JP, Supple GE, Hutchinson MD, Frankel DS, Marchlinski FE., Heart Rhythm 2012; PO06-06.
- Mobile thrombus on implantable defibrillator and pacemaker leads identified with intracardiac echocardiography.Supple GE, Ren JF, Zado ES, Marchlinski FE., Heart Rhythm 2010;7:S310.
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Professional Memberships
- Fellow
- Fellow
- Member
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