Guillermo James Tearney MD PhD

Pathology•Boston, MA

Anatomic Pathology, Clinical Pathology

Professor of Pathology, Massachusetts General Hospital

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55 Fruit StBhx 604aBoston, MA 02114
Phone+1 617-724-2979
Fax+1 617-726-4103

Education & Training

Mass General Brigham/Massachusetts General HospitalResidency, Pathology-Anatomic and Clinical, 1998 - 2001
Harvard Medical SchoolClass of 1998

Certifications & Licensure

MA State Medical License 2000 - 2025
American Board of Pathology Anatomic Pathology

Awards, Honors, & Recognition

Fellow (FACC) American College of Cardiology

Clinical Trials

Identifying Vulnerable Plaques in Blood Vessels of the Heart Using a New Imaging Technique Start of enrollment: 2007 Jul 25
ACTIVE_NOT_RECRUITING
NA
Optical Coherence Tomography (OCT) Based Screening of Esophagus and Gastroesophageal Junction Start of enrollment: 2006 Sep 01
Completed
Not Applicable
Evaluate the Use of Optical Frequency Domain Imaging (OFDI) for Celiac Disease in Children, Adolescents and Young Adults Start of enrollment: 2009 Aug 01
Completed
Not Applicable
Optical Frequency Domain Imaging for Assessing Colonic Polyps Start of enrollment: 2009 Jul 01
Completed
Not Applicable
Optical Frequency Domain Imaging (OFDI) Assessment in Radiofrequency Ablation Start of enrollment: 2008 Oct 01
Completed
Not Applicable
Optical Frequency Domain Imaging (OFDI) for Biliary Stricture Imaging Start of enrollment: 2009 Feb 01
Completed
Not Applicable
Optical Frequency Domain Imaging (OFDI) Surveillance and Image Guided Biopsy of the Esophagus Start of enrollment: 2010 Oct 01
Completed
Not Applicable
Using Spectrally Encoded Confocal Microscopy (SECM) to Image the Esophagus Start of enrollment: 2013 Oct 01
Active, not recruiting
Not Applicable
Imaging the Duodenum Using an Optical Frequency Domain Imaging OFDI Capsule Start of enrollment: 2013 Sep 16
Enrolling by invitation
Not Applicable
Study to Image the Esophagus Using the OFDI Capsule Start of enrollment: 2012 Feb 01
Completed
Not Applicable
OFDI Capsule Imaging in Patients With Atrial Fibrillation Undergone Radio Frequency (RF) Ablation Start of enrollment: 2013 Jan 01
Completed
Not Applicable
Using Spectrally Encoded Confocal Microscopy (SECM) to Visualise the Esophagus Using an SECM Probe Start of enrollment: 2014 Jun 01
Completed
Not Applicable
Natural History of Barrett's Esophagus Using Tethered Capsule Endomicroscopy Start of enrollment: 2016 Dec 01
Active, not recruiting
Coordinating Center: Natural History of Barrett's Esophagus Using Tethered Capsule Endomicroscopy Start of enrollment: 2017 Apr 04
Active, not recruiting
Not Applicable
Imaging of the Esophagus Using a SECM Capsule Start of enrollment: 2025 Jan 01
Not yet recruiting
Not Applicable
Pilot Study for Evaluation of Cryobiopsy and Correlation With Standard Forceps Biopsy Start of enrollment: 2018 Sep 05
Active, not recruiting
Not Applicable
Capsule Endomicroscopy for Visualization of the Small Intestine in EED Population in Pakistan Start of enrollment: 2017 Oct 11
Enrolling by invitation
Not Applicable
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Publications & Presentations

PubMed

A thin cryobiopsy device compatible with transnasal endoscopy for the gastrointestinal tract.
David O Otuya, Hamid Farrokhi, Yogesh Verma, Jing Dong, Peter Choy
Science Translational Medicine. 2025-04-30
Toward in vivo bronchoscopic functional CFTR assessment using a short circuit current measurement probe.
David O Otuya, Zhongyu Liu, Reny Joseph, Mohammed A Hanafy, Kadambari Vijaykumar
American Journal of Physiology. Lung Cellular and Molecular Physiology. 2025-02-01
2 citations
Emerging Hybrid Intracoronary Imaging Technologies and Their Applications in Clinical Practice and Research.
Vincenzo Tufaro, Farouc A Jaffer, Patrick W Serruys, Yoshinobu Onuma, Antonius F W van der Steen
JACC. Cardiovascular Interventions. 2024-09-09

Journal Articles

A Revised Airway Epithelial Hierarchy Includes CFTR-Expressing Ionocytes
Guillermo J Tearney, Jayaraj Rajagopal, Steven M Rowe, Vladimir Vinarsky, Nature

Press Mentions

7 Recent Reports on the EsophagusFebruary 5th, 2021
New Developments in Optical Sensing Technology: An Interview with Adrien DesjardinsJanuary 10th, 2020
New Intra-Nasal Imaging to Study Airways in Patients with Cystic FibrosisAugust 7th, 2019
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Grant Support

Multimodality Micro-Optical Coherence Tomography for Imaging the Functional Microanatomy of the Human CochleaSTANFORD UNIVERSITY2025–2029
Colorectal Cancer Screening with Optical Coherence TomographyMASSACHUSETTS GENERAL HOSPITAL2024–2029
Colorectal Cancer Screening with Optical Coherence TomographyMASSACHUSETTS GENERAL HOSPITAL2024–2029
Colorectal Cancer Screening with Optical Coherence TomographyMASSACHUSETTS GENERAL HOSPITAL2024–2029
Colorectal Cancer Screening with Optical Coherence TomographyMASSACHUSETTS GENERAL HOSPITAL2024–2029
Clinical translation of targeted intracoronary imaging for inflammatory activityMASSACHUSETTS GENERAL HOSPITAL2022–2027
Clinical translation of targeted intracoronary imaging for inflammatory activityMASSACHUSETTS GENERAL HOSPITAL2022–2027
Clinical translation of targeted intracoronary imaging for inflammatory activityMASSACHUSETTS GENERAL HOSPITAL2022–2027
Clinical translation of targeted intracoronary imaging for inflammatory activityMASSACHUSETTS GENERAL HOSPITAL2022–2027
Clinical translation of targeted intracoronary imaging for inflammatory activityMASSACHUSETTS GENERAL HOSPITAL2022–2027
Screening for Barrett's Esophagus Progressors with Multimodality Tethered Capsule Image-Guided BiopsyMASSACHUSETTS GENERAL HOSPITAL2022–2026
Screening for Barrett's Esophagus Progressors with Multimodality Tethered Capsule Image-Guided BiopsyMASSACHUSETTS GENERAL HOSPITAL2022–2026
Screening for Barrett's Esophagus Progressors with Multimodality Tethered Capsule Image-Guided BiopsyMASSACHUSETTS GENERAL HOSPITAL2022–2026
Screening for Barrett's Esophagus Progressors with Multimodality Tethered Capsule Image-Guided BiopsyMASSACHUSETTS GENERAL HOSPITAL2022–2026
Screening for Barrett's Esophagus Progressors with Multimodality Tethered Capsule Image-Guided BiopsyMASSACHUSETTS GENERAL HOSPITAL2022–2026
Screening for Barrett's Esophagus Progressors with Multimodality Tethered Capsule Image-Guided BiopsyMASSACHUSETTS GENERAL HOSPITAL2022–2026
Screening for Barrett's Esophagus Progressors with Multimodality Tethered Capsule Image-Guided BiopsyMASSACHUSETTS GENERAL HOSPITAL2022–2026
Dynamic µOCT for cellular tissue phenotypingMASSACHUSETTS GENERAL HOSPITAL2021–2026
Dynamic µOCT for cellular tissue phenotypingMASSACHUSETTS GENERAL HOSPITAL2021–2026
Dynamic µOCT for cellular tissue phenotypingMASSACHUSETTS GENERAL HOSPITAL2021–2026
Dynamic µOCT for cellular tissue phenotypingMASSACHUSETTS GENERAL HOSPITAL2021–2026
Dynamic µOCT for cellular tissue phenotypingMASSACHUSETTS GENERAL HOSPITAL2021–2026
Dynamic µOCT for cellular tissue phenotypingMASSACHUSETTS GENERAL HOSPITAL2021–2026
A tethered capsule endoscopic-endomicroscopic (TEEM) approach for improving upper GI tract diagnosisMASSACHUSETTS GENERAL HOSPITAL2019–2024
Unique value of real-time shear stress to enhance coronary disease managementMASSACHUSETTS GENERAL HOSPITAL2018–2024
Biological Models, Molecular Pathology And BiostatisticsNational Cancer Institute2009–2012
Natural History Of Vulnerable Coronary PlaquesNational Heart, Lung, And Blood Institute2004–2012
Transnasal Probe For Diagnosing Eosinophilic EsophagitisNational Institute Of Diabetes And Digestive And Kidney Diseases2011
Improving Screening And Surveillance In Barrett'S PatientsNational Cancer Institute2010–2011
Chemical Analysis Of Coronary Atherosclerosis In PatientsNational Heart, Lung, And Blood Institute2008–2011
Comprehensive Confocal Microscopy For Image Guided BiopsyNational Cancer Institute2009–2010
Miniature Laser Therapy EndoscopeNational Institute Of Biomedical Imaging And Bioengineering2007–2009
Comprehensive Architectural And Cellular Endoscopic MicroscopyNational Cancer Institute2006–2007
Improving Screening &Surveillance In Barrett'S PatientsNational Cancer Institute2003–2007
Minority Predoctoral Fellowship ProgramNational Institute Of Arthritis And Musculoskeletal And Skin Diseases1991–1995