HaidongDongMD

PubMed

• Syngeneic murine models with distinct immune microenvironments represent subsets of human intrahepatic cholangiocarcinoma.
  Jennifer L Tomlinson, Binbin Li, Jingchun Yang, Emilien Loeuillard, Hannah E Stumpf, Hendrien Kuipers, Ryan Watkins, Danielle M Carlson, Jessica Willhite, Daniel R O'B...> ;Journal of Hepatology. 2024 Mar 7
• 1 citations
  Neoadjuvant cobimetinib and atezolizumab with or without vemurafenib for high-risk operable Stage III melanoma: the Phase II NeoACTIVATE trial.
  Domingo-Musibay, E., Hieken, T., Nelson, G., Flotte, T., Grewal, E., Chen, J., McWilliams, R., Kottschade, L., Yang, L., Domingo-Musibay, E., Dronca, R., Yan, Y., Mark...> ;Nature Communications. 2024 Feb 16
• 1 citations
  Noncanonical TRAIL Signaling Promotes Myeloid-Derived Suppressor Cell Abundance and Tumor Growth in Cholangiocarcinoma.
  Emilien J Loeuillard, Binbin Li, Hannah E Stumpf, Jingchun Yang, Jessica R Willhite, Jennifer L Tomlinson, Fred Rakhshan Rohakhtar, Vernadette A Simon, Rondell P Graha...> ;Cellular and Molecular Gastroenterology and Hepatology. 2024 Jan 14
• Master Transcription Factor Reprogramming Unleashes Selective Translation Promoting Castration Resistance and Immune Evasion in Lethal Prostate Cancer.
  Santasusagna, S., Zhu, S., Jawalagatti, V., Carceles-Cordon, M., Ertel, A., Garcia-Longarte, S., Song, W., Fujiwara, N., Li, P., Mendizabal, I., Petrylak, D., Kelly, W...> ;Cancer Discovery. 2023 Dec 12
• Salvage therapy expands highly cytotoxic and metabolically fit resilient CD8T cells via ME1 up-regulation.
  Joanina K Gicobi, Zhiming Mao, Grace DeFranco, Jacob B Hirdler, Ying Li, Vianca V Vianzon, Emilia R Dellacecca, Michelle A Hsu, Whitney Barham, Yiyi Yan, Aaron S Mansf...> ;Science Advances. 2023 Nov 17
• 1 citations
  TREM2 mediates MHCII-associated CD4+ T cell response against gliomas.
  Jiaying Zheng, Lingxiao Wang, Shunyi Zhao, Wenjing Zhang, Yuzhou Chang, Dale B Bosco, Tao Huang, Aastha Dheer, Shan Gao, Shengze Xu, Katayoun Ayasoufi, Rawan Al-Kharbo...> ;Neuro-Oncology. 2023 Nov 6
• 4 citations
  Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity.
  Wenqun Zhong, Youtao Lu, Xuexiang Han, Jingbo Yang, Zhiyuan Qin, Wei Zhang, Ziyan Yu, Bin Wu, Shujing Liu, Wei Xu, Cathy Zheng, Lynn M Schuchter, Giorgos C Karakousis,...> ;Cell Reports. 2023 Oct 31
• 5 citations
  Single cell RNA sequencing unravels mechanisms underlying senescence-like phenotypes of alveolar macrophages.
  Yue Wu, Shengen Shawn Hu, Ruixuan Zhang, Nick P Goplen, Xiaochen Gao, Harish Narasimhan, Ao Shi, Yin Chen, Ying Li, Chongzhi Zang, Haidong Dong, Thomas J Braciale, Bib...> ;Iscience. 2023 Jul 21
• Circulating antigen-primed cytotoxic T-cells in patients with renal tumors treated with surgery.
  Rodrigo Rodrigues Pessoa, Henan Zhang, Andrew Zganjar, Reza Nabavizadeh, Vignesh T Packiam, Christine M Lohse, John C Cheville, Lance C Pagliaro, Brian A Costello, Ste...> ;Urologic Oncology. 2023 Sep 1
• Secreted ORF8 induces monocytic pro-inflammatory cytokines through NLRP3 pathways in patients with severe COVID-19.
  Xiaosheng Wu, Michelle K Manske, Gordon J Ruan, Taylor L Witter, Kevin E Nowakowski, Jithma P Abeykoon, Xinyi Tang, Yue Yu, Kimberly A Gwin, Annie Wu, Vanessa Taupin, ...> ;Iscience. 2023 Jun 16
• 1 citations
  Single cell profiling at the maternal-fetal interface reveals a deficiency of PD-L1 non-immune cells in human spontaneous preterm labor.
  Xiao Liu, Ivy Aneas, Noboru Sakabe, Rebecca L Anderson, Christine Billstrand, Cristina Paz, Harjot Kaur, Brian Furner, Seong Choi, Adriana Y Prichina, Elizabeth Ann L ...> ;Scientific Reports. 2023 May 16
• A Novel PD-L1 Antibody Promotes Antitumor Function of Peripheral Cytotoxic Lymphocytes after Radical Nephrectomy in Patients with Renal Cell Carcinoma.
  Zesheng An, Michelle A Hsu, Joanina K Gicobi, Tianxiao Xu, Susan M Harrington, Henan Zhang, Kevin D Pavelko, Jacob B Hirdler, Christine M Lohse, Reza Nabavizadeh, Rodr...> ;Journal of Immunology. 2023 Jun 15
• TREM2 mediates MHCII-associated CD4T cell response against gliomas.
  Jiaying Zheng, Lingxiao Wang, Shunyi Zhao, Wenjing Zhang, Yuzhou Chang, Aastha Dheer, Shan Gao, Shengze Xu, Katayoun Ayasoufi, Rawan Al-Kharboosh, Manling Xie, Aaron J...> ;Biorxiv. 2023 Apr 6
• 8 citations
  Cytokines and Immune Cell Phenotype in Acute Kidney Injury Associated With Immune Checkpoint Inhibitors.
  Naba Farooqui, Mark Zaidi, Lisa Vaughan, Trevor D McKee, Eram Ahsan, Kevin D Pavelko, Jose C Villasboas, Svetomir Markovic, Timucin Taner, Nelson Leung, Haidong Dong, ...> ;Kidney International Reports. 2023 Mar 1
• 1 citations
  A Novel Humanized PD-1/PD-L1 Mouse Model Permits Direct Comparison of Antitumor Immunity Generated by Food and Drug Administration-Approved PD-1 and PD-L1 Inhibitors.
  Whitney Barham, Michelle Hsu, Xin Liu, Susan M Harrington, Jacob B Hirdler, Joanina K Gicobi, Xingxing Zhu, Hu Zeng, Kevin D Pavelko, Yiyi Yan, Aaron S Mansfield, Haid...> ;Immunohorizons. 2023 Jan 1
• 3 citations
  Resilient T-cell responses in patients with advanced cancers.
  Joanina K Gicobi, Emilia R Dellacecca, Haidong Dong> ;International Journal of Hematology. 2023 May 1
• 7 citations
  Evaluation of PD-L1 and B7-H3 expression as a predictor of response to adjuvant chemotherapy in bladder cancer.
  Ahmed M Mahmoud, Igor Frank, Jacob J Orme, Roxane R Lavoie, Prabin Thapa, Brian A Costello, John C Cheville, Sounak Gupta, Haidong Dong, Fabrice Lucien> ;BMC Urology. 2022 Jun 24
• 1 citations
  Impact of PD-1 Blockade in Nonresponders: Pitfalls and Promise.
  Harry H Yoon, Haidong Dong, Qian Shi> ;Clinical Cancer Research. 2022 Aug 2
• 4 citations
  Tumor-Derived Extracellular Vesicles Predict Clinical Outcomes in Oligometastatic Prostate Cancer and Suppress Antitumor Immunity.
  Fabrice Lucien, Yohan Kim, Jing Qian, Jacob J Orme, Henan Zhang, Ali Arafa, Feven Abraha, Ishwor Thapa, Erik J Tryggestad, William S Harmsen, Jorgena Kosti, Hesham Ali...> ;International Journal of Radiation Oncology, Biology, Physics. 2022 Nov 15
• 6 citations
  Rescuing Cancer Immunity by Plasma Exchange in Metastatic Melanoma (ReCIPE-M1): protocol for a single-institution, open-label safety trial of plasma exchange to clear ...
  Tara M Davidson, Nathan Foster, Fabrice Lucien, Svetomir Markovic, Haidong Dong, Jeffrey L Winters, Sean S Park, Jacob J Orme> ;BMJ Open. 2022 May 12
• 20 citations
  Pembrolizumab in Combination with Neoadjuvant Chemoradiotherapy for Patients with Resectable Adenocarcinoma of the Gastroesophageal Junction.
  Mojun Zhu, Chunhua Chen, Nathan R Foster, Christopher Hartley, Taofic Mounajjed, Marcela A Salomao, Briant F Fruth, Staci E Beamer, Yohan Kim, Susan M Harrington, Henr...> ;Clinical Cancer Research. 2022 Jul 15
• 4 citations
  Cutting Edge: Enhanced Antitumor Immunity in ST8Sia6 Knockout Mice.
  David J Friedman, Monika Kizerwetter, Paul Belmonte, Matthew Rajcula, Keith Theodore, Hyun Se Kim Lee, Michael J Shapiro, Haidong Dong, Virginia Smith Shapiro> ;Journal of Immunology. 2022 Apr 15
• 6 citations
  Understanding Suboptimal Response to Immune Checkpoint Inhibitors.
  Mojun Zhu, Henan Zhang, Katrina S Pedersen, Nathan R Foster, Brandy L Jaszewski, Xin Liu, Jacob B Hirdler, Zesheng An, Tanios S Bekaii-Saab, Thorvardur R Halfdanarson,...> ;Advanced Biology. 2023 Apr 1
• 4 citations
  Overcoming Immunotherapy Resistance With Radiation Therapy and Dual Immune Checkpoint Blockade.
  Tara Davidson, Henan Zhang, Haidong Dong, Michael P Grams, Sean S Park, Yiyi Yan> ;Advances in Radiation Oncology. 2022 Mar 1
• 13 citations
  PD-L1 promotes myofibroblastic activation of hepatic stellate cells by distinct mechanisms selective for TGF-β receptor I versus II.
  Liankang Sun, Yuanguo Wang, Xianghu Wang, Amaia Navarro-Corcuera, Sumera Ilyas, Nidhi Jalan-Sakrikar, Can Gan, Xinyi Tu, Yu Shi, Kangsheng Tu, Qingguang Liu, Zhenkun L...> ;Cell Reports. 2022 Feb 8
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Journal Articles

• Exosomal PD-L1 Contributes to Immunosuppression and Is Associated with Anti-PD-1 Response  
  Xiaowei Xu, Haidong Dong, Tara C Mitchell, Lynn M Schuchter, Alexander C Huang, Suzanne McGettigan, Wei Xu, Giorgos C Karakousis, Xiaoming Liu, Gordon Mills, Nature

Abstracts/Posters

• Tumor ADAM10/ADAM17-Mediated PD-L1 Loss May Predict Poor Outcomes in Diffuse Large B Cell Lymphoma
  Haidong Dong, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019