Howard J. Worman MD

PubMed

• Farnesylated prelamin A induces fibroblast polarity defects in premature aging disorders by inhibiting nesprin-2-SUN2 LINC complex function.
  Chonkit Lio, Yuexia Wang, Paige C Wilson, Yutao Li, Susumu Antoku
  Journal of Cell Science. 2026-04-21
• Stem cell-associated osteogenic deficiency causes craniofacial deformities with progeroid accumulation of prelamin A.
  Kai Li, Trunee Hsu, Hitoshi Uchida, Tingxi Wu, Susan Michaelis
  JCI Insight. 2026-03-09
• 1 citations
  Nesprin-2 contains BH3-like motifs that can promote cell death.
  Hila Zohar, Amit Kessel, Liora Lindenboim, Dang Nguyen, Nir Ben-Tal
  Cell Death Discovery. 2025-06-03

Journal Articles

• Cell signaling abnormalities in cardiomyopathy caused by lamin A/C gene mutations  
  Worman, H. J., Biochem. Soc. Trans., 1/1/2018
• Gunter Blobel: Pioneer of molecular cell biology (1936�2018)  
  Blobel Laboratory Trainees (authors in footnote), J. Cell Biol., 1/1/2018
• Permanently farnesylated prelamin A, progeria and atherosclerosis  
  Worman, H. J. and Michaelis, S., Circulation, 1/1/2018

Books/Book Chapters

• The LINC Complex: Methods and Protocols. Methods in Molecular Biology 
  Editors: Gundersen, G. G. and Worman, H. J..Humana Press, New York2018
• The LINC Complex: Methods and Protocols 
  Chapter: Next-generation sequencing and mutational analysis: implications for genes encoding LINC complex proteins 
  Page 321.0 - 336.0Nagy, P. L and Worman, H. J.Editors: Gundersen G. G. and Worman, H. J..Humana Press, New York2018
• The Functional Nucleus 
  Chapter: Human diseases related to nuclear envelope proteins 
  Page 3.0 - 25.0Worman, H. J.Editors: Bazett-Jones, D. J. and Dellaire, G..Springer International Publishing, Cham, SwitzerlandEdition 1st,2016

Lectures

• Entertaining Science: From Nuclear Membranes to Aging�What a Long, Strange Trip It�s Been 
  The Cornelia Street Cafe, New York, NY - 1/1/2018
• Biomedical Research in the Next Decade 
  New York, NY - 1/1/2018
• A Precision Medicine Approach to the Laminopathies 
  Multiple locations, 2016, 2017 - 1/1/2017

Other

• Computers and technology: creating a website 
  Worman, H. J., AGA News
  1/1/1997
• Electronic prescription services offer potential savings and improvements in efficiencies 
  Weinstein, D. R. and Worman, H. J., AGA News
  1/1/1997
• Military AIDS tests can't be conclusive (letter) 
  Worman, H. J., The New York Times
  1/28/1985