Isaac Samuel Kohane MD
Pediatric Endocrinology
Lawrence J. Henderson Professor of Pediatrics, Boston Children's Hospital
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300 Longwood AveDivision Of EndocrinologyBoston, MA 02115
Phone+1 617-355-7476
Fax+1 617-730-0194
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Education & Training
Boston Children’s Hospital/Boston Medical CenterFellowship, Pediatric Endocrinology, 1990 - 1993- Boston Children’s Hospital/Boston Medical CenterResidency, Pediatrics, 1987 - 1989
Boston University School of MedicineClass of 1987
Certifications & Licensure
MA State Medical License 1990 - 2027
Awards, Honors, & Recognition
- Elected Member Institute of Medicine, 2009
- Elected Member The American Society for Clinical Investigation, 2005
Clinical Trials
- Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network Start of enrollment: 2015 Sep 16
Roles: Contact
Publications & Presentations
PubMed
- Phenotypic prediction of missense variants via deep contrastive learning.Jun Wen, Sihang Zeng, Clara-Lea Bonzel, Shilpa Nadimpalli Kobren, Jiangchuan Du
Nature Biomedical Engineering. 2026-04-14 - Heterogenous effect of automated alerts on mortality.Benjamin D Wissel, Zana Percy, Tanner J Zachem, Brett Beaulieu-Jones, Isaac S Kohane
Journal of the American Medical Informatics Association. 2026-03-01 - Forecasting left ventricular systolic dysfunction in heart failure with artificial intelligence.Teya Bergamaschi, Tiffany Yau, Payal Chandak, Abena Kyereme-Tuah, Judy Hung
Eclinicalmedicine. 2026-02-01
Press Mentions
A.I. Is Making Doctors Answer a Question: What Are They Really Good For?February 9th, 2026- AI Reduces Medical Errors by 16% in Real-World Kenyan Clinic TrialAugust 4th, 2025
- AI Helps Prevent Medical Errors in Real-World ClinicsJuly 22nd, 2025
Grant Support
- Diagnosing the Unknown for Care and Advancing Science (DUCAS)HARVARD MEDICAL SCHOOL2023–2028
- Diagnosing the Unknown for Care and Advancing Science (DUCAS)HARVARD MEDICAL SCHOOL2023–2028
- Informatics For Integrating Biology &The Bedside (I2B2)National Library Of Medicine2010–2011
- Core 6 AdministrationNational Library Of Medicine2010–2011
- Core 5 DisseminationNational Library Of Medicine2010–2011
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