IvanLuptakJr.MDPhD

PubMed

• Hemodynamic testing to guide vasodilator therapy in cardiac amyloidosis.
  Dane M Rucker, Omar K Siddiqi, David R Pimentel, Ivan Luptak> ;Journal of Cardiology Cases. 2023 Sep 1
• 4 citations
  SGLT2 inhibitor ertugliflozin decreases elevated intracellular sodium, and improves energetics and contractile function in diabetic cardiomyopathy.
  Dominique Croteau, Tomas Baka, Sara Young, Huamei He, Jordan M Chambers, Fuzhong Qin, Marcello Panagia, David R Pimentel, James A Balschi, Wilson S Colucci, Ivan Luptak> ;Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 2023 Apr 1
• 2 citations
  Multi-Omics Profiling of Hypertrophic Cardiomyopathy Reveals Altered Mechanisms in Mitochondrial Dynamics and Excitation-Contraction Coupling.
  Jarrod Moore, Jourdan Ewoldt, Gabriela Venturini, Alexandre C Pereira, Kallyandra Padilha, Matthew Lawton, Weiwei Lin, Raghuveera Goel, Ivan Luptak, Valentina Perissi,...> ;International Journal of Molecular Sciences. 2023 Mar 1
• 1 citations
  Ivabradine in the Management of COVID-19-related Cardiovascular Complications: A Perspective.
  Tomas Baka, Kristina Repova, Ivan Luptak, Fedor Simko> ;Current Pharmaceutical Design. 2022 Jan 1
• 12 citations
  A Novel Small Molecule Troponin Activator Increases Cardiac Contractile Function Without Negative Impact on Energetics.
  Huamei He, Tomas Baka, James A. Balschi, Alykhan Motani, Kathy Nguyen, Qingxiang Liu, Rebecca Slater, Brooke M. Rock, Chen Wang, Christopher M. Hale, Georgios Karamanl...> ;Circulation. Heart Failure. 2021 Oct 28
• 34 citations
  Effects of Sodium-Glucose Linked Transporter 2 Inhibition With Ertugliflozin on Mitochondrial Function, Energetics, and Metabolic Gene Expression in the Presence and A...
  Dominique Croteau, Ivan Luptak, Jordan M. Chambers, Ion A. Hobai, Marcello Panagia, David R. Pimentel, Deborah A. Siwik, Fuzhong Qin, Wilson S. Colucci> ;Journal of the American Heart Association. 2021 Jul 6
• 16 citations
  Redox-Resistant SERCA [Sarco(endo)plasmic Reticulum Calcium ATPase] Attenuates Oxidant-Stimulated Mitochondrial Calcium and Apoptosis in Cardiac Myocytes and Pressure ...
  Jena B Goodman, Fuzhong Qin, Robert J. Morgan, Jordan M. Chambers, Dominique Croteau, Deborah A. Siwik, Ion A. Hobai, Marcello Panagia, Ivan Luptak, Markus Bachschmid,...> ;Circulation. 2020 Dec 22
• 23 citations
  Role of Glutaredoxin-1 and Glutathionylation in Cardiovascular Diseases.
  Mannix Burns, Syed Husain Mustafa Rizvi, Yuko Tsukahara, David R. Pimentel, Ivan Luptak, Naomi M. Hamburg, Reiko Matsui, Markus Bachschmid> ;International Journal of Molecular Sciences. 2020 Sep 16
• 16 citations
  Differential Effects of Sacubitril/Valsartan on Diastolic Function in Mice With Obesity-Related Metabolic Heart Disease
  Dominique Croteau, Fuzhong Qin, Jordan M. Chambers, Ethan Kallick, Ivan Luptak, Marcello Panagia, David R. Pimentel, Deborah A. Siwik, Wilson S. Colucci> ;JACC. Basic to Translational Science. 2020 Sep 9
• 1 citations
  A novel tracer for in vivo optical imaging of fatty acid metabolism in the heart and brown adipose tissue.
  Marcello Panagia, Jing Yang, Eric M. Gale, Huan Wang, Ivan Luptak, Howard H. Chen, Dakshesh Patel, Dominique Croteau, David R. Pimentel, Markus Bachschmid, Wilson S. C...> ;Scientific Reports. 2020 Jul 8
• 7 citations
  Increasing mitochondrial ATP synthesis with butyrate normalizes ADP and contractile function in metabolic heart disease
  Marcello Panagia, Huamei He, Tomas Baka, David R. Pimentel, Dominique Croteau, Markus Bachschmid, James A. Balschi, Wilson S. Colucci, Ivan Luptak> ;NMR in Biomedicine. 2020 May 1
• 71 citations
  Production of adeno-associated virus vectors for in vitro and in vivo applications.
  Toyokazu Kimura, Beatriz Ferrán, Yuko Tsukahara, Qifan Shang, Suveer Desai, Alessandra Fedoce, David R. Pimentel, Ivan Luptak, Takeshi Adachi, Yasuo Ido, Reiko Matsui,...> ;Scientific Reports. 2019 Sep 19
• 1 citations
  Genetically targeted fluorescent probes reveal dynamic calcium responses to adrenergic signaling in multiple cardiomyocyte compartments
  Ivan Luptak, Robert J. Morgan, Tomas Baka, Dominique Croteau, Daniel Moverman, Hannah Sarnak, Michael T. Kirber, Markus Bachschmid, Wilson S. Colucci, David R. Pimentel> ;The International Journal of Biochemistry & Cell Biology. 2019 Sep 1
• 19 citations
  Energetic Dysfunction Is Mediated by Mitochondrial Reactive Oxygen Species and Precedes Structural Remodeling in Metabolic Heart Disease
  Ivan Luptak, Fuzhong Qin, Aaron L. Sverdlov, David R. Pimentel, Marcello Panagia, Dominique Croteau, Deborah A. Siwik, Markus Bachschmid, Huamei He, James A. Balschi, ...> ;Antioxidants & Redox Signaling. 2019 Jul 17
• 9 citations
  Myocardial Redox Hormesis Protects the Heart of Female Mice in Sepsis.
  Ivan Luptak, Dominique Croteau, Catherine Valentine, Fuzhong Qin, Deborah A. Siwik, Daniel G. Remick, Wilson S. Colucci, Ion A. Hobai> ;Shock. 2019 Jul 1
• 13 citations
  Use of Ventilatory Efficiency Slope as a Marker for Increased Mortality in Wild-Type Transthyretin Cardiac Amyloidosis.
  Adil Yunis, G. Doros, Ivan Luptak, Lawreen H. Connors, Flora Sam> ;The American Journal of Cardiology. 2019 Jul 1
• 4 citations
  Multiplexed Optical Imaging of Energy Substrates Reveals That Left Ventricular Hypertrophy Is Associated With Brown Adipose Tissue Activation.
  Marcello Panagia, Howard H. Chen, Dominique Croteau, Yin-Ching Iris Chen, Chongzhao Ran, Ivan Luptak, Lee Josephson, Wilson S. Colucci, David E. Sosnovik> ;Circulation. Cardiovascular Imaging. 2018 Mar 1
• 65 citations
  Decreased ATP production and myocardial contractile reserve in metabolic heart disease.
  Ivan Luptak, Aaron L. Sverdlov, Marcello Panagia, Fuzhong Qin, David R. Pimentel, Dominique Croteau, Deborah A. Siwik, Joanne S. Ingwall, Markus Bachschmid, James A. B...> ;Journal of Molecular and Cellular Cardiology. 2018 Feb 1
• 34 citations
  Glucose transporter 4-deficient hearts develop maladaptive hypertrophy in response to physiological or pathological stresses
  Adam R. Wende, Jaetaek Kim, William L. Holland, Benjamin Wayment, Brian T. O’Neill, Joseph Tuinei, Manoja K. Brahma, Mark E Pepin, Mark A. McCrory, Ivan Luptak, Ganesh...> ;American Journal of Physiology. Heart and Circulatory Physiology. 2017 Dec 1
• 7 citations
  Partial Liver Kinase B1 (LKB1) Deficiency Promotes Diastolic Dysfunction, De Novo Systolic Dysfunction, Apoptosis, and Mitochondrial Dysfunction With Dietary Metabolic...
  Edward J. Miller, Timothy D. Calamaras, Aly Elezaby, Aaron L. Sverdlov, Fuzhong Qin, Ivan Luptak, Ke Wang, Xinxin Sun, Andrea Vijay, Dominique Croteau, Markus Bachschm...> ;Journal of the American Heart Association. 2016 Jan 26
• 81 citations
  Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet-Induced Metabolic Heart Disease.
  Aaron L. Sverdlov, Aly Elezaby, Fuzhong Qin, Jessica B. Behring, Ivan Luptak, Timothy D. Calamaras, Deborah A. Siwik, Edward J. Miller, Marc Liesa, Orian S. Shirihai, ...> ;Journal of the American Heart Association. 2016 Jan 11
• 60 citations
  High fat, high sucrose diet causes cardiac mitochondrial dysfunction due in part to oxidative post-translational modification of mitochondrial complex II
  Aaron L. Sverdlov, Aly Elezaby, Jessica B. Behring, Markus Bachschmid, Ivan Luptak, Vivian H. Tu, Deborah A. Siwik, Edward J. Miller, Marc Liesa, Orian S. Shirihai, Da...> ;Journal of Molecular and Cellular Cardiology. 2015 Jan 1
• 50 citations
  Mitochondrial remodeling in mice with cardiomyocyte-specific lipid overload
  Aly Elezaby, Aaron L. Sverdlov, Vivian H. Tu, Kanupriya Soni, Ivan Luptak, Fuzhong Qin, Marc Liesa, Orian S. Shirihai, Jamie M. Rimer, Jean E. Schaffer, Wilson S. Colu...> ;Journal of Molecular and Cellular Cardiology. 2015 Feb 1
• 28 citations
  Effects of Direct Renin Inhibition on Myocardial Fibrosis and Cardiac Fibroblast Function
  Hui Zhi, Ivan Luptak, Gaurav Alreja, Jianru Shi, Jian Guan, Nicole Metes-Kosik, Jacob Joseph> ;Plos One. 2013 Dec 11
• 85 citations
  Hydrogen Peroxide–Mediated SERCA Cysteine 674 Oxidation Contributes to Impaired Cardiac Myocyte Relaxation in Senescent Mouse Heart
  Fuzhong Qin, Deborah A. Siwik, Steve Lancel, Jingmei Zhang, Gabriela M. Kuster, Ivan Luptak, Lei Wang, Xiaoyong Tong, Y. James Kang, Richard A. Cohen, Wilson S. Colucci> ;Journal of the American Heart Association. 2013 Aug 12
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