J.EduardoRameMD

Cardiology • Philadelphia, PA

Cardiac Electrophysiology, Heart Failure & Transplantation

Chief of Advanced Cardiac and Pulmonary Vascular Disease and Louis R. Dinon, MD Professor of Clinical Cardiology

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Office
3400 Spruce Street
6 Penn Tower
Philadelphia, PA 19104
Phone+1 215-615-0800
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Education & Training

Johns Hopkins UniversityFellowship, Cardiovascular Disease, 2002 - 2005
University of Texas Southwestern Medical CenterResidency, Internal Medicine, 1997 - 2000
Harvard Medical SchoolClass of 1997

Certifications & Licensure

CA State Medical License 2005 - Present
PA State Medical License 2009 - 2024
TX State Medical License 2000 - 2007
American Board of Internal Medicine Advanced Heart Failure and Transplant Cardiology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013

Clinical Trials

REGISTRY EVALUATION OF VITAL INFORMATION FOR VADs IN AMBULATORY LIFE Start of enrollment: 2015 Jul 01
Completed
Phase III Clinical Worsening Study of UT-15C in Subjects With PAH Receiving Background Oral Monotherapy Start of enrollment: 2012 Jun 26
Completed
Phase 3
An Open-Label, Long-Term Study of Oral Treprostinil in Subjects With Pulmonary Arterial Hypertension Start of enrollment: 2013 Sep 11
Completed
Phase 3
Remission From Stage D Heart Failure Start of enrollment: 2013 Jan 01
Unknown status
Phase 4
Impact of Hemodynamic Ramp Test-Guided HVAD RPM and Medication Adjustments on Exercise Tolerance and Quality of Life Start of enrollment: 2016 Mar 01
Completed
Not Applicable
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Publications & Presentations

PubMed

Predicted heart mass based on ideal body weight for donor-to-recipient size matching.
Danial Ahmad, Andrew Brodie, Christopher Pritting, Indranee Rajapreyar, J Eduardo Rame, Keshava Rajagopal, John W Entwistle, Howard Massey, Vakhtang Tchantchaleishvili> ;Clinical Transplantation. 2023 Dec 1
1 citations
Utility of Recipient Cardiothoracic Ratio in Predicting Delayed Chest Closure after Heart Transplantation.
Amrita Sukhavasi, Danial Ahmad, Melissa Austin, J Eduardo Rame, John W Entwistle, Howard T Massey, Vakhtang Tchantchaleishvili> ;The Thoracic and Cardiovascular Surgeon. 2023 Mar 9
1 citations
The Anemia Stress Index-Anemia, Transfusions, and Mortality in Patients with Continuous Flow Ventricular Assist Devices.
Supriya Shore, Thomas C Hanff, Jeremy A Mazurek, Arieh Fox, Monique S Tanna, Edward W Grandin, Robert Zhang, Joyce Wald, Carli Peters, Michael A Acker, Pavan Atluri, J...> ;Journal of Clinical Medicine. 2022 Aug 3
1 citations
Direct anabolic metabolism of three-carbon propionate to a six-carbon metabolite occurs in vivo across tissues and species.
Mary T Doan, Michael D Neinast, Erika L Varner, Kenneth C Bedi Jr, David Bartee, Helen Jiang, Sophie Trefely, Peining Xu, Jay P Singh, Cholsoon Jang, J Eduardo Rame, D...> ;Journal of Lipid Research. 2022 Jun 1
4 citations
Patient-specific severity of von Willebrand factor degradation identifies patients with a left ventricular assist device at high risk for bleeding.
Samson Hennessy-Strahs, Jooeun Kang, Eric Krause, Robert D Dowling, J Eduardo Rame, Carlo R Bartoli> ;The Journal of Thoracic and Cardiovascular Surgery. 2024 Jan 1
Cardiac transplantation after heparin-induced thrombocytopenia: A systematic review.
Diana C Jimenez, Eric D Warner, Danial Ahmad, Jake L Rosen, Nawar Al-Rawas, Rohinton J Morris, Rene Alvarez, J Eduardo Rame, John W Entwistle, H Todd Massey, Vakhtang ...> ;Clinical Transplantation. 2022 Feb 1
7 citations
Infective endocarditis following heart transplantation: A systematic review.
Andrew M. Jordan, Robert T. Tatum, Danial Ahmad, Sonali Patel, Elizabeth J. Maynes, Matthew P. Weber, Sean Moss, Tricia L. Royer, Vakhtang Tchantchaleishvili, H. Todd ...> ;Transplantation Reviews. 2022 Jan 1
33 citations
Evolution of Late Right Heart Failure With Left Ventricular Assist Devices and Association With Outcomes.
J. Eduardo Rame, Francis D. Pagani, Michael S. Kiernan, Guilherme H. Oliveira, Edo Y. Birati, Pavan Atluri, Ann C. Gaffey, E. Wilson Grandin, Susan L. Myers, Craig Col...> ;Journal of the American College of Cardiology. 2021 Dec 7
34 citations
Quantitative subcellular acyl-CoA analysis reveals distinct nuclear metabolism and isoleucine-dependent histone propionylation
Sophie Trefely, Katharina Huber, Joyce Liu, Michael Noji, Stephanie Stransky, Jay Singh, Mary T. Doan, Claudia D. Lovell, Eliana von Krusenstiern, Helen Jiang, Anna Bo...> ;Molecular Cell. 2021 Dec 1
1 citations
3 Cases of Superior Vena Cava Syndrome Following Percutaneous Right Ventricular Assist Device Placement
BS John R. Vaile, J. Eduardo Rame, Rene Alvarez, H.T. Massey, Vakhtang Tchantchaleishvili, Alec Vishnevsky, Indranee Rajapreyar, DO Yevgeniy Brailovsky, Mahek Shah> ;JACC. Case Reports. 2021 Nov 3
1 citations
Left Ventricular Assist Device as a Bridge to Recovery: Single Center Experience of Successful Device Explantation.
Robert S Zhang, Thomas C. Hanff, Carli J. Peters, Peter T. Evans, Judy Marble, J. Eduardo Rame, Pavan Atluri, Kimberly Urgo, Monique S. Tanna, Jeremy A. Mazurek, Micha...> ;ASAIO Journal. 2021 Sep 20
1 citations
Association of Health Insurance Payer Type and Outcomes After Durable Left Ventricular Assist Device Implantation: An Analysis of the STS-INTERMACS Registry
Sameed Ahmed M. Khatana, Thomas C. Hanff, Ashwin S. Nathan, Elias J. Dayoub, E. Wilson Grandin, J. Eduardo Rame, Alexander C. Fanaroff, Jay Giri, Peter W. Groeneveld> ;Circulation. Heart Failure. 2021 May 1
3 citations
Left Ventricular End-Diastolic Dimension and Clinical Outcomes After Centrifugal Flow Left Ventricular Assist Device Implantation.
Vien T. Truong, Satya Shreenivas, Wojciech Mazur, Gregory F. Egnaczyk, Cassady Palmer, Sriram D. Rao, J. Eduardo Rame, Chung, E., Eugene S. Chung> ;ASAIO Journal. 2021 Apr 21
6 citations
Coagulopathy monitoring and anticoagulation management in COVID-19 patients on ECMO: Advantages of a heparin anti-Xa-based titration strategy.
Ruben Rhoades, Ron Leong, Jason Kopenitz, Brandi Thoma, Lydia McDermott, Joseph Dovidio, Shannon Barletti, Jerald Z. Gong, H.T. Massey, Steven E. McKenzie, J. Eduardo ...> ;Thrombosis Research. 2021 Apr 19
13 citations
Early Usage of Extracorporeal Membrane Oxygenation in the Absence of Invasive Mechanical Ventilation to Treat COVID-19-related Hypoxemic Respiratory Failure.
Pranav Loyalka, Faisal H. Cheema, Harshit Rao, J. Eduardo Rame, Keshava Rajagopal> ;ASAIO Journal. 2021 Apr 1
9 citations
Outcomes of Mechanical Circulatory Support for Giant Cell Myocarditis: A Systematic Review.
Preeyal M. Patel, Abhiraj Saxena, Chelsey T. Wood, Thomas J. O’Malley, Elizabeth J. Maynes, John W. Entwistle, H. Todd Massey, Preethi Pirlamarla, Rene Alvarez, Leslie...> ;Journal of Clinical Medicine. 2020 Nov 30
9 citations
The effect of transfusion of blood products on ventricular assist device support outcomes.
Supriya Shore, Thomas C. Hanff, Jeremy A. Mazurek, Matthew Seigerman, Robert S Zhang, E.W. Grandin, Esther Vorovich, Paul J. Mather, Caroline Olt, Jessica L. Howard, J...> ;ESC Heart Failure. 2020 Oct 14
4 citations
Medicaid Expansion and Ventricular Assist Device Implantation: An Analysis of the INTERMACS Registry.
Sameed Ahmed M. Khatana, E. Wilson Grandin, J. Eduardo Rame, Changyu Shen, Robert W. Yeh, Peter W. Groeneveld> ;Journal of the American College of Cardiology. 2020 Sep 22
Cost-Effectiveness of Long-Term Left Ventricular Assist Device Support: Is the Extra-Welfarist Model Suitable for Advanced Heart Failure?
Indranee Rajapreyar, J. Eduardo Rame> ;ASAIO Journal. 2020 Aug 1
5 citations
Treatment With Impella Increases the Risk of De Novo Aortic Insufficiency Post Left Ventricular Assist Device Implant
Sriram D. Rao, Bryce V. Johnson, Salim E. Olia, Joyce Wald, Venessa Medina, J. Eduardo Rame, Jeremy A. Mazurek, Lee R. Goldberg, Pavan Atluri, Christian A. Bermudez, M...> ;Journal of Cardiac Failure. 2020 Jul 15
2 citations
A Modified Grading System for Early Right Heart Failure Matches Functional Outcomes and Survival After Left Ventricular Assist Devices.
E. Wilson Grandin, Gregory S. Troutman, Arune A Gulati, Payman Zamani, Jeremy A. Mazurek, Pavan Atluri, J. Eduardo Rame> ;ASAIO Journal. 2021 Feb 1
9 citations
Not All Septal Defects Are Equal: Outcomes of Bilateral Lung Transplant With Cardiac Defect Repair vs Combined Heart-Lung Transplant in Patients With Eisenmenger Syndr...
F. Sertic, Jason J. Han, Dieynaba Diagne, Thomas Richards, Lexy Chavez, Ashley Berg, Joyce Wald, J. Eduardo Rame, Maria M. Crespo, Christian A. Bermudez> ;Chest. 2020 Jun 18
85 citations
Updated definitions of adverse events for trials and registries of mechanical circulatory support: A consensus statement of the mechanical circulatory support academic...
Robert L. Kormos, Christiaan F J Antonides, Daniel J. Goldstein, Jennifer A Cowger, Randall C. Starling, James K. Kirklin, J. Eduardo Rame, David N. Rosenthal, Martha ...> ;The Journal of Heart and Lung Transplantation. 2020 Apr 18
Reversing Heart Failure With a Ventricular Anchoring Device: Another Hope for Myopathic Mitral Regurgitation∗
J. Eduardo Rame> ;JACC. Basic to Translational Science. 2020 Mar 23
69 citations
Combination therapy with oral treprostinil for pulmonary arterial hypertension: A double-blind placebo-controlled clinical trial
R. James White, Carlos Jerjes-Sánchez, Gisela Martina Bohns Meyer, Tomas Pulido, Pablo Sepúlveda, Kuo Yang Wang, Ekkehard Grünig, Shirish Hiremath, Zaixin Yu, Gangchen...> ;American Journal of Respiratory and Critical Care Medicine. 2020 Mar 15
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