JaclynFrancesHechtmanMD

PubMed

• 1 citations
  Microsatellite Instability and Mismatch Repair Deficiency Define a Distinct Subset of Lung Cancers Characterized by Smoking Exposure, High Tumor Mutational Burden, and...
  Soo-Ryum Yang, Erika Gedvilaite, Ryan Ptashkin, Jason Chang, John Ziegler, Douglas A Mata, Liliana B Villafania, Khedoudja Nafa, Jaclyn F Hechtman, Ryma Benayed, Ahmet...> ;Journal of Thoracic Oncology. 2024 Mar 1
• Her2 low (but not negative): the newest biomarker on the block for gastro-oesophageal adenocarcinoma.
  Jaclyn Frances Hechtman> ;Journal of Clinical Pathology. 2023 Dec 1
• Determinants of Survival with Combined HER2 and PD-1 Blockade in Metastatic Esophagogastric Cancer.
  Steven B Maron, Walid Chatila, Henry Walch, Joanne F Chou, Nicholas Ceglia, Ryan Ptashkin, Richard Kinh Gian Do, Viktoriya Paroder, Neeta Pandit-Taskar, Jason S Lewis,...> ;Clinical Cancer Research. 2023 Sep 15
• 5 citations
  Integrated clinical and genomic analysis identifies driver events and molecular evolution of colitis-associated cancers.
  Walid K Chatila, Henry Walch, Jaclyn F Hechtman, Sydney M Moyer, Valeria Sgambati, David M Faleck, Amitabh Srivastava, Laura Tang, Jamal Benhamida, Dorina Ismailgeci, ...> ;Nature Communications. 2023 Jan 7
• 1 citations
  Recurrent Loss of Heterozygosity in Pancreatic Neuroendocrine Tumors.
  Megan Parilla, David Chapel, Jaclyn F Hechtman, Pankhuri Wanjari, Tony El Jabbour, Lauren Ritterhouse, Jeremy Segal, Chad Vanderbilt, David S Klimstra, Namrata Setia, ...> ;The American Journal of Surgical Pathology. 2022 Jun 1
• 7 citations
  ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1.
  Wenjing Su, Radha Mukherjee, Rona Yaeger, Jieun Son, Jianing Xu, Na Na, Neilawattie Merna Timaul, Jaclyn Hechtman, Viktoriya Paroder, Mika Lin, Marissa Mattar, Juan Qi...> ;Molecular Cell. 2022 Jul 7
• 1 citations
  Same-Cell Co-Occurrence of RAS Hotspot and BRAF V600E Mutations in Treatment-Naive Colorectal Cancer.
  Rodrigo Gularte-Mérida, Shaleigh Smith, Anita S Bowman, Arnaud da Cruz Paula, Walid Chatila, Craig M Bielski, Monika Vyas, Laetitia Borsu, Ahmet Zehir, Luciano G Marte...> ;JCO Precision Oncology. 2022 Mar 1
• 5 citations
  Defining and Targeting Esophagogastric Cancer Genomic Subsets With Patient-Derived Xenografts.
  Ryan H Moy, Henry S Walch, Marissa Mattar, Walid K Chatila, Daniela Molena, Vivian E Strong, Laura H Tang, Steven B Maron, Daniel G Coit, David R Jones, Jaclyn F Hecht...> ;JCO Precision Oncology. 2022 Feb 1
• 30 citations
  Carcinomas assemble a filamentous CXCL12-keratin-19 coating that suppresses T cell-mediated immune attack.
  Zhikai Wang, Philip Moresco, Ran Yan, Jiayun Li, Ya Gao, Daniele Biasci, Min Yao, Jordan Pearson, Jaclyn F Hechtman, Tobias Janowitz, Raza M Zaidi, Matthew J Weiss, Do...> ;Proceedings of the National Academy of Sciences of the United States of America. 2022 Jan 25
• 5 citations
  Diagnostic testing approaches for the identification of patients with TRK fusion cancer prior to enrollment in clinical trials investigating larotrectinib.
  Erin R Rudzinski, Jaclyn Hechtman, Sinchita Roy-Chowdhuri, Marion Rudolph, Christina M Lockwood, Josh Silvertown, Justyna Wierzbinska, Kui Shen, Ricarda Norenberg, Hen...> ;Cancer Genetics. 2022 Jan 1
• 46 citations
  NTRK insights: best practices for pathologists
  Jaclyn F. Hechtman> ;Modern Pathology. 2021 Sep 16
• 4 citations
  Molecular Approach to Colorectal Carcinoma: Current Evidence and Clinical Application.
  Cameron Beech, Jaclyn F. Hechtman> ;Surgical Pathology Clinics. 2021 Sep 1
• 12 citations
  Prevalence of Germline Alterations on Targeted Tumor-Normal Sequencing of Esophagogastric Cancer.
  Geoffrey Y. Ku, Yelena Kemel, Steve B. Maron, Joanne F. Chou, Vignesh Ravichandran, Zarina Shameer, Anna Maio, Elizabeth Won, David P. Kelsen, David H. Ilson, Marinela...> ;JAMA Network Open. 2021 Jul 1
• 52 citations
  Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via paired normal sequencing using MSK-ACCESS.
  A. Rose Brannon, Gowtham Jayakumaran, Monica Diosdado, Juber Patel, Anna Razumova, Yu Hu, Fanli Meng, Mohammad Haque, Justyna Sadowska, Brian J. Murphy, Tessara Baldi,...> ;Nature Communications. 2021 Jun 18
• 10 citations
  EGFR Amplification in Metastatic Colorectal Cancer.
  Giovanni Randon, Rona Yaeger, Jaclyn F. Hechtman, Paolo Manca, Giovanni Fucà, Henry Walch, Jeeyun Lee, Elena Elez, J. Seligmann, Benedetta Mussolin, Filippo Pagani, Ma...> ;Journal of the National Cancer Institute. 2021 Nov 2
• 7 citations
  Next-Generation Sequencing of 487 Esophageal Adenocarcinomas Reveals Independently Prognostic Genomic Driver Alterations and Pathways.
  Smita Sihag, Samuel C Nussenzweig, Henry Walch, Meier Hsu, Kay See Tan, Francisco Sanchez-Vega, Walid K. Chatila, Sergio De La Torre, Assem Patel, Yelena Y. Janjigian,...> ;Clinical Cancer Research. 2021 Apr 1
• 64 citations
  Genetic Determinants of Outcome in Intrahepatic Cholangiocarcinoma
  Thomas Boerner, Esther Drill, Linda M. Pak, Bastien Nguyen, Carlie S. Sigel, Alexandre Doussot, Paul Shin, Debra A. Goldman, Mithat Gonen, Peter J. Allen, Vinod P. Bal...> ;Hepatology. 2021 Sep 1
• 1 citations
  Reply to Singh et al.
  Jaclyn F. Hechtman, Robert A. Soslow, Jinru Shia> ;Modern Pathology. 2021 Mar 10
• 19 citations
  Current Management of Appendiceal Neoplasms
  Richard S. Hoehn, Nelya Melnitchouk, Jaclyn F. Hechtman, Nathan Bahary, Caroline J. Rieser, M. Haroon A. Choudry> ;American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting. 2021 Mar 25
• 66 citations
  Overcoming MET-dependent resistance to selective RET inhibition in patients with RET fusion-positive lung cancer by combining selpercatinib with crizotinib
  Ezra Y. Rosen, Melissa Lynne Johnson, Sarah E. Clifford, Romel Somwar, Jennifer Kherani, Jieun Son, Arrien A. Bertram, Monika A. Davare, Eric Gladstone, Elena Ivanova,...> ;Clinical Cancer Research. 2021 Jan 1
• 26 citations
  TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors
  Emiliano Cocco, Ji Eun Lee, Srinivasaraghavan Kannan, Alison M. Schram, Helen Won, Sophie Shifman, Amanda Kulick, Laura Baldino, Eneda Toska, Amaia Arruabarrena-Aristo...> ;Cancer Discovery. 2021 Jan 1
• 5 citations
  Pan-Cancer Biomarkers: Changing the Landscape of Molecular Testing.
  Jinjuan Yao, Maria E. Arcila, Marc Ladanyi, Jaclyn F. Hechtman> ;Archives of Pathology & Laboratory Medicine. 2021 Jun 1
• 36 citations
  A Performance Comparison of Commonly Used Assays to Detect RET Fusions
  Soo-Ryum Yang, Umut Aypar, Ezra Y. Rosen, Douglas A. Mata, Ryma Benayed, Kerry Mullaney, Gowtham Jayakumaran, Yanming Zhang, Denise Frosina, Alexander Drilon, Marc Lad...> ;Clinical Cancer Research. 2021 Mar 1
• 19 citations
  Characterization and Clinical Outcomes of DNA Mismatch Repair-deficient Small Bowel Adenocarcinoma.
  Alicia Latham, Jinru Shia, Zalak Patel, Diane Reidy-Lagunes, Neil H. Segal, Rona Yaeger, Karuna Ganesh, Louise Catherine Connell, Nancy E. Kemeny, David P. Kelsen, Jac...> ;Clinical Cancer Research. 2021 Mar 1
• 6 citations
  Discordant DNA mismatch repair protein status between synchronous or metachronous gastrointestinal carcinomas: frequency, patterns, and molecular etiologies
  Monika Vyas, Canan Firat, Jaclyn F. Hechtman, Martin R. Weiser, Rona Yaeger, Chad M. Vanderbilt, Jamal Benhamida, Ajaratu Keshinro, Liying Zhang, Peter Ntiamoah, Marco...> ;Familial Cancer. 2021 Jul 1
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