JacobOrmeMDPhD

PubMed

• Low PSA radiographic disease progression on C11-choline PET.
  Mahmoud, A., Kendi, A., Ahmed, M., Thorpe, M., Johnson, G., Riaz, I., Orme, J., Kwon, E., Andrews, J., Childs, D.> ;BJUI Compass. 2024 Mar 1
• A real-world experience of pembrolizumab monotherapy in microsatellite instability-high and/or tumor mutation burden-high metastatic castration-resistant prostate canc...
  Mosalem, O., Tan, W., Bryce, A., Dronca, R., Childs, D., Pagliaro, L., Orme, J., Kase, A.> ;Prostate Cancer and Prostatic Diseases. 2024 Feb 10
• The yin and yang of chromosomal instability in prostate cancer.
  Carceles-Cordon, M., Domingo-Domenech, J., Rodriguez-Bravo, V., Orme, J.> ;Nature Reviews. Urology. 2024 Feb 2
• Delaying Prostate-Specific Antigen Progression in Biochemically Recurrent Prostate Cancer: Is It Clinically Meaningful?
  Daniel S Childs, Jacob J Orme, Praful Ravi> ;Journal of Clinical Oncology. 2024 Apr 1
• Co-occurring BRCA2/SPOP Mutations Predict Exceptional Poly (ADP-ribose) Polymerase Inhibitor Sensitivity in Metastatic Castration-Resistant Prostate Cancer.
  Orme, J., Taza, F., De Sarkar, N., Tewari, A., Arsalan Naqvi, S., Riaz, I., Childs, D., Omar, N., Adra, N., Ashkar, R., Cheng, H., Schweizer, M., Sokolova, A., Agarwal...> ;European Urology Oncology. 2023 Dec 9
• Prostate Cancer and Malignant Ascites: The Mayo Clinic Experience With a Rare and Aggressive Disease Progression.
  Ahmed M Mahmoud, Jacob J Orme, Daniel S Childs, Mohamed E Ahmed, Anne Rajkumar, Eugene D Kwon, Jack R Andrews> ;Clinical Genitourinary Cancer. 2024 Apr 1
• Salvage therapy expands highly cytotoxic and metabolically fit resilient CD8T cells via ME1 up-regulation.
  Joanina K Gicobi, Zhiming Mao, Grace DeFranco, Jacob B Hirdler, Ying Li, Vianca V Vianzon, Emilia R Dellacecca, Michelle A Hsu, Whitney Barham, Yiyi Yan, Aaron S Mansf...> ;Science Advances. 2023 Nov 17
• 1 citations
  Treatment modalities and survival outcomes in prostate cancer parenchymal brain metastasis.
  Ahmed M Mahmoud, Daniel S Childs, Mohamed E Ahmed, A Tuba Kendi, Geoffrey B Johnson, Jacob J Orme, Bradley J Stish, Ryan M Phillips, Sean S Park, Brian J Davis, Jack R...> ;The Prostate. 2024 Feb 1
• 4 citations
  Real-World Outcomes With Lurbinectedin in Second-Line Setting and Beyond for Extensive Stage Small Cell Lung Cancer.
  Aakash Desai, Caleb J Smith, Yash Ashara, Jacob J Orme, Saurabh Zanwar, Ashley Potter, Craig Hocum, J Nicole Moffett, Anna J Schwecke, Rami Manochakian, Yanyan Lou, Yu...> ;Clinical Lung Cancer. 2023 Dec 1
• 2 citations
  An evaluation of the effect of lithium on taxane-induced neuropathy.
  David C Kochan, Paul J Novotny, Elizabeth J Cathcart-Rake, Jacob J Orme, Amye J Tevaarwerk, Kathryn J Ruddy, Daniel S Childs> ;Supportive Care in Cancer. 2023 Apr 25
• 2 citations
  Hidden tricks in MATH: Hypermorphic mutations in SPOP tumor suppressor explained by cryo-EM.
  Jacob J Orme, Georges Mer, Haojie Huang> ;Molecular Cell. 2023 Mar 2
• Antibody-Based Therapeutics for the Treatment of Renal Cell Carcinoma: Challenges and Opportunities.
  Ahmed M Mahmoud, Reza Nabavizadeh, Rodrigo Rodrigues Pessoa, Ishita Garg, Jacob Orme, Brian A Costello, John Cheville, Fabrice Lucien> ;The Oncologist. 2023 Apr 6
• 3 citations
  SETDB1 Modulates Degradation of Phosphorylated RB and Anticancer Efficacy of CDK4/6 Inhibitors.
  Zhenlin Huang, Xiang Li, Bo Tang, Hao Li, Jianong Zhang, Rui Sun, Jian Ma, Yunqian Pan, Binyuan Yan, Yingke Zhou, Donglin Ding, Yuqian Yan, Rafael Jimenez, Jacob J Orm...> ;Cancer Research. 2023 Mar 15
• 2 citations
  Slow Uptake of an Effective Therapy: Patterns of Olanzapine Prescribing for Those Receiving Highly Emetogenic Chemotherapy.
  Daniel S Childs, David A Helfinstine Jr, Lindsey Sangaralingham, Jacob J Orme, Ciara C O'Sullivan, Charles L Loprinzi, Kathryn J Ruddy> ;JCO Oncology Practice. 2022 Dec 1
• 5 citations
  Radiation Therapy in Oligometastatic Prostate Cancer.
  Siven Chinniah, Bradley Stish, Brian A Costello, Lance Pagliaro, Daniel Childs, Fernando Quevedo, Fabrice Lucien, Alan Bryce, Sean S Park, Jacob J Orme> ;International Journal of Radiation Oncology, Biology, Physics. 2022 Nov 15
• 7 citations
  Evaluation of PD-L1 and B7-H3 expression as a predictor of response to adjuvant chemotherapy in bladder cancer.
  Ahmed M Mahmoud, Igor Frank, Jacob J Orme, Roxane R Lavoie, Prabin Thapa, Brian A Costello, John C Cheville, Sounak Gupta, Haidong Dong, Fabrice Lucien> ;BMC Urology. 2022 Jun 24
• 4 citations
  Tumor-Derived Extracellular Vesicles Predict Clinical Outcomes in Oligometastatic Prostate Cancer and Suppress Antitumor Immunity.
  Fabrice Lucien, Yohan Kim, Jing Qian, Jacob J Orme, Henan Zhang, Ali Arafa, Feven Abraha, Ishwor Thapa, Erik J Tryggestad, William S Harmsen, Jorgena Kosti, Hesham Ali...> ;International Journal of Radiation Oncology, Biology, Physics. 2022 Nov 15
• 4 citations
  Economic Cost and Sustainability of Oral Therapies in Precision Oncology.
  Aakash P Desai, Caleb J Scheckel, Leah C Soderberg, Chelsee J Jensen, Jacob J Orme, Sri H Tella, Anuhya Kommalapati, Joshua C Pritchett, Nandita Khera, Amit Mahipal, R...> ;JCO Oncology Practice. 2022 Aug 1
• 6 citations
  Rescuing Cancer Immunity by Plasma Exchange in Metastatic Melanoma (ReCIPE-M1): protocol for a single-institution, open-label safety trial of plasma exchange to clear ...
  Tara M Davidson, Nathan Foster, Fabrice Lucien, Svetomir Markovic, Haidong Dong, Jeffrey L Winters, Sean S Park, Jacob J Orme> ;BMJ Open. 2022 May 12
• HUS1 as a Potential Therapeutic Target in Urothelial Cancer.
  Andrea Katharina Lindner, Tobias Furlan, Jacob J Orme, Gennadi Tulchiner, Nina Staudacher, David D'Andrea, Zoran Culig, Renate Pichler> ;Journal of Clinical Medicine. 2022 Apr 15
• Rational Second-Generation Antiandrogen Use in Prostate Cancer.
  Jacob J Orme, Lance C Pagliaro, J Fernando Quevedo, Sean S Park, Brian A Costello> ;The Oncologist. 2022 Mar 4
• 13 citations
  Trends in Prices of Drugs Used to Treat Metastatic Non-Small Cell Lung Cancer in the US From 2015 to 2020.
  Aakash Desai, Caleb Scheckel, Chelsee J Jensen, Jacob Orme, Colt Williams, Nilay Shah, Konstantinos Leventakos, Alex A Adjei> ;JAMA Network Open. 2022 Jan 4
• 12 citations
  Phase II Evaluation of Stereotactic Ablative Radiotherapy (SABR) and Immunity in 11C-Choline-PET/CT-Identified Oligometastatic Castration-Resistant Prostate Cancer.
  Henan Zhang, Jacob J. Orme, F. Abraha, B.J. Stish, Val J. Lowe, Fabrice Lucien, Erik J. Tryggestad, Michael S. Bold, Lance C. Pagliaro, C. Richard Choo, Debra H. Brink...> ;Clinical Cancer Research. 2021 Sep 30
• 3 citations
  Chemotherapy with atezolizumab for small cell or neuroendocrine carcinoma of the prostate: A single institution experience.
  Christopher E. Wee, Brian A. Costello, Jacob J. Orme, J. Fernando Quevedo, Lance C. Pagliaro> ;The Prostate. 2021 Jul 12
• 6 citations
  CMTM6 expression as a potential biomarker for immunotherapy in metastatic renal cell carcinoma
  Gennadi Tulchiner, Andrea Brunner, Manuela Schmidinger, Nina Staudacher, Jacob J. Orme, Martin Thurnher, Wolfgang Horninger, Zoran Culig, Renate Pichler> ;BJU International. 2021 Jul 1
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Lectures

• Tumor ADAM10/ADAM17-Mediated PD-L1 Loss May Predict Poor Outcomes in Diffuse Large B Cell Lymphoma 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019