JamesR.BrownMD

PubMed

• Airway host-microbiome interactions in chronic obstructive pulmonary disease.
  Wang, Z.,Maschera, B.,Lea, S.,Kolsum, U.,Michalovich, D.,Van Horn, S.,Traini, C.,Brown, J. R.,Hessel, E. M.,Singh, D.> ;Respir. Res.. 2019 Jun 07
• Longitudinal Profiling of the Lung Microbiome in the AERIS Study Demonstrates Repeatability of Bacterial and Eosinophilic COPD Exacerbations
  James Brown, MD> ;Emergency Medicine Journal. 2018 Feb 02
• Gut microbiome differences between metformin- and liraglutide-treated T2DM subjects.
  Wang, Z.,Saha, S.,Van Horn, S.,Thomas, E.,Traini, C.,Sathe, G.,Rajpal, D. K.,Brown, J. R.> ;Endocrinol Diabetes Metab. 2017 Dec 28
• Meta-analysis of human gene expression in response to Mycobacterium tuberculosis infection reveals potential therapeutic targets.
  Wang, Z.,Arat, S.,Magid-Slav, M.,Brown, J. R.> ;BMC Syst Biol. 2018 Jan 13
• Sputum microbiome temporal variability and dysbiosis in chronic obstructive pulmonary disease exacerbations: an analysis of the COPDMAP study.
  Wang, Z.,Singh, R.,Miller, B. E.,Tal-Singer, R.,Van Horn, S.,Tomsho, L.,Mackay, A.,Allinson, J. P.,Webb, A. J.,Brookes, A. J.,George, L. M.,Barker, B.,Kolsum, U.,Donne...> ;Thorax. 2017 Dec 23
• Human Microbial Metabolites as a Source of New Drugs
  James Brown, MD> ;ScienceDirect. 2016 Feb 27
• Microbiome changes in healthy volunteers treated with GSK1322322, a novel antibiotic targeting bacterial peptide deformylase.
  Arat, S.,Spivak, A.,Van Horn, S.,Thomas, E.,Traini, C.,Sathe, G.,Livi, G. P.,Ingraham, K.,Jones, L.,Aubart, K.,Holmes, D. J.,Naderer, O.,Brown, J. R.> ;Antimicrob. Agents Chemother.. 2014 Dec 10
• Bacterial resistance to leucyl-tRNA synthetase inhibitor GSK2251052 develops during treatment of complicated urinary tract infections.
  O'Dwyer, K.,Spivak, A. T.,Ingraham, K.,Min, S.,Holmes, D. J.,Jakielaszek, C.,Rittenhouse, S.,Kwan, A. L.,Livi, G. P.,Sathe, G.,Thomas, E.,Van Horn, S.,Miller, L. A.,Tw...> ;Antimicrob. Agents Chemother.. 2014 Oct 29
• Translating the human microbiome.
  Brown, J.,de Vos, W. M.,DiStefano, P. S.,Doré, J.,Huttenhower, C.,Knight, R.,Lawley, T. D.,Raes, J.,Turnbaugh, P.> ;Nat. Biotechnol.. 2013 Apr 09
• Computational biology approaches for selecting host-pathogen drug targets.
  Brown, J. R.,Magid-Slav, M.,Sanseau, P.,Rajpal, D. K.> ;Drug Discov. Today. 2011 Feb 01
• Phylogenomics of phosphoinositide lipid kinases: perspectives on the evolution of second messenger signaling and drug discovery.
  Brown, J. R.,Auger, K. R.> ;BMC Evol. Biol.. 2011 Jan 07
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