James Alexander Fagin MD
Diabetes, Lipid Metabolism, Thyroid
Head, Division of Subspecialty Medicine Memorial Sloan Kettering Cancer Center
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530 East 74th StreetNew York, NY 10021
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Education & Training
Cedars-Sinai Medical CenterFellowship, Endocrinology, Diabetes, and Metabolism, 1983 - 1985
University of Buenos AiresClass of 1973
Certifications & Licensure
CA State Medical License 1986 - Present
FL State Medical License 2021 - Present
NY State Medical License 2006 - 2026
NJ State Medical License 2021 - 2025
OH State Medical License 1995 - 2007
American Board of Internal Medicine Internal Medicine
Awards, Honors, & Recognition
- Elected Member Association of American Physicians, 2001
- Top Doctors: New York Metro Area Castle Connolly, 2014
- Elected Member The American Society for Clinical Investigation, 1995
Clinical Trials
- Reacquisition of Radioactive Iodine (RAI) Uptake of RAI-Refractory Metastatic Thyroid Cancers by Pretreatment With the Selective MEK Inhibitor AZD6244 Start of enrollment: 2009 Sep 01
- Vemurafenib Plus Copanlisib in Radioiodine-Refractory (RAIR) Thyroid Cancers Start of enrollment: 2020 Jun 26
Roles: Contact
Publications & Presentations
PubMed
- 1 citationsRBM10 loss promotes metastases by aberrant splicing of cytoskeletal and extracellular matrix mRNAs.Gnana P Krishnamoorthy, Anthony R Glover, Brian R Untch, Nickole Sigcha-Coello, Bin Xu
The Journal of Experimental Medicine. 2025-05-05 - 3 citationsHigh-Grade Follicular Cell-Derived Non-Anaplastic Thyroid Carcinoma: Correlating Extent of Invasion and Mutation Profile with Oncologic Outcome.Daniel W Scholfield, Bin Xu, Helena Levyn, Alana Eagan, Ashok R Shaha
Thyroid. 2025-02-01 - Comprehensive Mass Spectral Libraries of Human Thyroid Tissues and Cells.Lu Li, Wenhao Jiang, Wenjun Wei, Gnana P Krishnamoorthy, Pingping Hu
Scientific Data. 2024-12-28
Journal Articles
- Vemurafenib Redifferentiation of BRAF Mutant, RAI-Refractory Thyroid CancersSteven M Larson, Sofia Haque, Duan Li, R Michael Tuttle, Mona M Sabra, Alan L Ho, Eric J Sherman, Ravinder K Grewal, James A Fagin, David G Pfister, Ronald A Ghossein, The Journal of Clinical Endocrinology and Metabolism
- Radioactive Iodine-Related Clonal Hematopoiesis in Thyroid Cancer Is Common and Associated with Decreased SurvivalJames Fagin, MD, The Journal of Clinical Endocrinology and Metabolism
- Methodology, Criteria and Characterization of Patient-Matched Thyroid Cell Lines and Patient-Derived Tumor XenograftsJames A Fagin, Stephen D Rohl, Robert C Smallridge, Stefan K Grebe, The Journal of Clinical Endocrinology and Metabolism
Press Mentions
Novel Agent Nixes Radioiodine Resistance in Thyroid CancerOctober 7th, 2020
Bench to Bedside: Translating Science from the Lab to the ClinicMay 2nd, 2019
87th Annual Meeting NewsOctober 20th, 2017- Join now to see all
Grant Support
- Targeting immune suppressive microenvironment in ATCSLOAN-KETTERING INST CAN RESEARCH2021–2026
- Targeting immune suppressive microenvironment in ATCSLOAN-KETTERING INST CAN RESEARCH2021–2026
- Improving efficacy of radioiodine treatment of thyroid cancerSLOAN-KETTERING INST CAN RESEARCH2021–2026
- Oncogenic Events In Thyroid NeoplasiaNational Cancer Institute2006–2012
- Molecular Pathophysiology Of Thyroid Cell GrowthNational Cancer Institute2006–2012
- A Validated Resource Of Thyroid Cancer Cell Lines For Pathway DiscoveryNational Cancer Institute2009–2010
- Paracrine Igf/Gfbp Interactions In VivoNational Institute Of Diabetes And Digestive And Kidney Diseases2006–2007
- Paracrine Igf/Gfbp Interactions In VivoNational Institute Of Diabetes And Digestive And Kidney Diseases2003–2006
- Oncogenic Events In Thyroid NeoplasiaNational Cancer Institute1997–2006
- Molecular Pathophysiology Of Thyroid Cell GrowthNational Cancer Institute1995–2004
- Biological And Physiological Sciences Review SectionCenter For Scientific Review2001–2002
- Paracrine IGF/IGFBP Interactions In VivoNational Institute Of Diabetes And Digestive And Kidney Diseases1998–2002
- Molecular Pathophysiology Of Thyroid Cell GrowthNational Center For Research Resources2000–2001
- N-Acetylcysteine As A Potential Treatment For Methamphetamine DependenceCenter For Scientific Review2000
- Insulin LIKE Growth Factor I In Arterial Wall InjuryNational Heart, Lung, And Blood Institute1995–1996
- Insulin LIKE Growth Factor I In Arterial Wall InjuryNational Heart, Lung, And Blood Institute1994
- Molecular Pathophysiology Of Thyroid Cell GrowthNational Cancer Institute1989–1993
- Tumor Suppressor Genes In Human Thyroid NeoplasmsNational Cancer Institute1990
- Human Growth Hormone-Secreting Hybrid CellsNational Institute Of Diabetes And Digestive And Kidney Diseases1985–1986
Other Languages
- Spanish
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