JamesHermanMD

PubMed

• Phase 2 study of epigenetic priming with decitabine followed by cytarabine for acute myeloid leukemia in older patients.
  Normolle, D., Bovbjerg, D., Im, A., Quann, K., Agha, M., Raptis, A., Redner, R., Hou, J., Farah, R., Dorritie, K., Sehgal, A., Aggarwal, N., Herman, J., Lontos, K., Bo...> ;American Journal of Hematology. 2024 Mar 1
• Methylation of NRIP3 Is a Synthetic Lethal Marker for Combined PI3K and ATR/ATM Inhibitors in Colorectal Cancer.
  Meiying Zhang, Xiaoyun Li, James G Herman, Aiai Gao, Qian Wang, Yuanxin Yao, Fangfang Shen, Kunlun He, Mingzhou Guo> ;Clinical and Translational Gastroenterology. 2024 Mar 1
• 1 citations
  RASSF1A promotes ATM signaling andmethylation is a synthetic lethal marker for ATR inhibitors.
  Aiai Gao, Panpan Bai, Meiying Zhang, Yuanxin Yao, James G Herman, Mingzhou Guo> ;Epigenomics. 2023 Nov 1
• 7 citations
  Multiplex Digital Methylation-Specific PCR for Noninvasive Screening of Lung Cancer.
  Yang Zhao, Christine M O'Keefe, Kuangwen Hsieh, Leslie Cope, Sonali C Joyce, Thomas R Pisanic, James G Herman, Tza-Huei Wang> ;Advanced Science. 2023 Jun 1
• 1 citations
  Response to Neoadjuvant Targeted Therapy in Operable Head and Neck Cancer Confers Survival Benefit.
  Marco A Mascarella, Tolani F Olonisakin, Purva Rumde, Varun Vendra, Melonie A Nance, Seungwon Kim, Mark W Kubik, Shaum S Sridharan, Robert L Ferris, Moon J Fenton, Dan...> ;Clinical Cancer Research. 2023 Feb 16
• Improving lung cancer diagnosis with cancer, fungal, and imaging biomarkers.
  Hannah N Marmor, Michael N Kammer, Stephen A Deppen, Maren Shipe, Valerie F Welty, Khushbu Patel, Caroline Godfrey, Ehab Billatos, James G Herman, David O Wilson, Aman...> ;The Journal of Thoracic and Cardiovascular Surgery. 2023 Sep 1
• 5 citations
  Epigenetic silencing of JAM3 promotes esophageal cancer development by activating Wnt signaling.
  Weili Yang, Chao Guo, James G Herman, Cheng Zhu, Honghui Lv, Xiaomo Su, Lirong Zhang, Meiying Zhang, Mingzhou Guo> ;Clinical Epigenetics. 2022 Dec 2
• 1 citations
  Lessons From a Systematic Literature Search on Diagnostic DNA Methylation Biomarkers for Colorectal Cancer: How to Increase Research Value and Decrease Research Waste?
  Zheng Feng, Cary J G Oberije, Alouisa J P van de Wetering, Alexander Koch, Kim A D Wouters, Nathalie Vaes, Ad A M Masclee, Beatriz Carvalho, Gerrit A Meijer, Maurice P...> ;Clinical and Translational Gastroenterology. 2022 Jun 1
• 4 citations
  Technical considerations in PCR-based assay design for diagnostic DNA methylation cancer biomarkers.
  Maartje Massen, Kim Lommen, Kim A D Wouters, Johan Vandersmissen, Wim van Criekinge, James G Herman, Veerle Melotte, Leo J Schouten, Manon van Engeland, Kim M Smits> ;Clinical Epigenetics. 2022 Apr 27
• 395 citations
  Analysis of DNA methylation in cancer: location revisited
  Alexander Koch, Sophie C. Joosten, Zheng Feng, Tim C. de Ruijter, Muriel X. G. Draht, Veerle Melotte, Kim M. Smits, Jürgen Veeck, James G. Herman, Leander Van Neste, W...> ;Nature Reviews. Clinical Oncology. 2018 Jul 1
• 25 citations
  Pembrolizumab plus azacitidine in patients with chemotherapy refractory metastatic colorectal cancer: a single-arm phase 2 trial and correlative biomarker analysis.
  Kuang, C., Park, Y., Augustin, R., Lin, Y., Hartman, D., Seigh, L., Pai, R., Sun, W., Bahary, N., Ohr, J., Rhee, J., Marks, S., Beasley, H., Shuai, Y., Herman, J., Zar...> ;Clinical Epigenetics. 2022 Jan 6
• 1 citations
  High-throughput sample processing for methylation analysis in an automated, enclosed environment.
  Alejandro Stark, Thomas R Pisanic 2nd, James G Herman, Tza-Huei Wang> ;SLAS Technology. 2022 Jun 1
• 3 citations
  Methylation of TMEM176A, a key ERK signaling regulator, is a novel synthetic lethality marker of ATM inhibitors in human lung cancer
  Hongxia Li, Weili Yang, Meiying Zhang, Tao He, Fuyou Zhou, James G. Herman, Liming Hu, Mingzhou Guo> ;Epigenomics. 2021 Sep 1
• 16 citations
  Methylation of NRN1 is a novel synthetic lethal marker of PI3K-Akt-mTOR and ATR inhibitors in esophageal cancer.
  Wushuang Du, Aiai Gao, James G. Herman, Lidong Wang, Lirong Zhang, Shunchang Jiao, Mingzhou Guo> ;Cancer Science. 2021 May 1
• 39 citations
  Advances in epigenetic therapeutics with focus on solid tumors.
  Ning Jin, Tiffany L. George, Gregory A. Otterson, Claire F. Verschraegen, Haitao Wen, David P. Carbone, James G. Herman, Erin M. Bertino, Kai He> ;Clinical Epigenetics. 2021 Apr 20
• 20 citations
  Identification of DNA methylation markers for early detection of CRC indicates a role for nervous system-related genes in CRC
  Glenn Rademakers, Maartje Massen, Alexander Koch, Muriel X. G. Draht, Nikkie Buekers, Kim A.D. Wouters, Nathalie Vaes, Tim De Meyer, Beatriz Carvalho, Gerrit A. Meijer...> ;Clinical Epigenetics. 2021 Apr 15
• 4 citations
  A phase 2 trial of gemcitabine and docetaxel in patients with metastatic colorectal adenocarcinoma with methylated checkpoint with forkhead and ring finger domain prom...
  Marina Baretti, Enusha Karunasena, Marianna Zahurak, Rosalind Walker, Yang Zhao, Thomas R. Pisanic, Tza-Huei Wang, Tim F. Greten, Austin G. Duffy, Elske Gootjes, Gerri...> ;Clinical and Translational Science. 2021 May 1
• 7 citations
  DNA-methylation for the detection and distinction of 19 human malignancies.
  Ludmila Danilova, John Wrangle, James G. Herman, Leslie Cope> ;Epigenetics. 2021 Mar 5
• 15 citations
  Noninvasive Diagnostics for Early Detection of Lung Cancer: Challenges and Potential with a Focus on Changes in DNA Methylation.
  Maria Farooq, James G. Herman> ;Cancer Epidemiology, Biomarkers & Prevention. 2020 Nov 4
• 11 citations
  HIST1H2BB and MAGI2 Methylation and Somatic Mutations as Precision Medicine Biomarkers for Diagnosis and Prognosis of High-grade Serous Ovarian Cancer
  Blanca L. Valle, Sebastian Rodriguez-Torres, Elisabetta Kuhn, Teresa Diaz-Montes, Edgardo Parrilla-Castellar, Fahcina Lawson, Oluwasina Folawiyo, Carmen Ili-Gangas, Pr...> ;Cancer Prevention Research. 2020 Jun 24
• 39 citations
  Detection of Promoter DNA Methylation in Urine and Plasma Aids the Detection of Non-Small Cell Lung Cancer.
  Bin Liu, Julio Ricarte Filho, Apurva Mallisetty, Cassandra Villani, Anastasia E. Kottorou, Kristen Rodgers, Chen Chen, Tomoaki Ito, Kyla Holmes, Nicole Gastala, Klara ...> ;Clinical Cancer Research. 2020 May 19
• 29 citations
  Ultrasensitive DNA hypermethylation detection using plasma for early detection of NSCLC: a study in Chinese patients with very small nodules.
  Chen Chen, Xiaojie Huang, Wei Yin, Muyun Peng, Fang Wu, Xia Wu, Jingqun Tang, Mingjiu Chen, Xiang Wang, Alicia Hulbert, Malcolm V. Brock, Wenliang Liu, James G. Herman...> ;Clinical Epigenetics. 2020 Mar 5
• 4 citations
  Development of flow cytometry assays for measuring cell-membrane enzyme activity on individual cells.
  Michael C. Gorry, Toshie Yoneyama, Lazar Vujanovic, Marcia L. Moss, Michelle A. Garlin, Miles A. Miller, James G. Herman, Laura P. Stabile, Nikola L. Vujanovic> ;Journal of Cancer. 2020 Jan 1
• 114 citations
  Epigenetic heterogeneity in cancer
  Mingzhou Guo, Yaojun Peng, Aiai Gao, Chen Du, James G. Herman> ;Biomarker Research. 2019 Oct 31
• 11 citations
  PTPRT epigenetic silencing defines lung cancer with STAT3 activation and can direct STAT3 targeted therapies
  Malabika Sen, Audrey Kindsfather, Ludmila Danilova, Feng Zhang, Raffaele Colombo, Matthew G. LaPorte, Brenda F. Kurland, Donna M. Huryn, Peter Wipf, James G. Herman> ;Epigenetics. 2020 Jul 2
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