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James Kirkland, MD, Geriatrics, Rochester, MN

JamesL.KirklandMD

Geriatrics Rochester, MN

Professor, Internal Medicine, Mayo Medical School

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Education & Training

  • Institute of Medical Science, University of Toronto
    Institute of Medical Science, University of TorontoPh.D., 1990
  • University of Manchester
    University of ManchesterM.Sc., 1982
  • University of Toronto Faculty of Medicine
    University of Toronto Faculty of MedicineClass of 1977

Certifications & Licensure

  • MA State Medical License
    MA State Medical License 1994 - 2025
  • MN State Medical License
    MN State Medical License 2008 - 2025
  • American Board of Internal Medicine Internal Medicine
  • American Board of Internal Medicine Endocrinology, Diabetes and Metabolism
  • American Board of Internal Medicine Geriatric Medicine

Awards, Honors, & Recognition

  • Excellence in Research Award Division of General Internal Medicine, Department of Internal Medicine, Mayo Clinic, Minnesota, 2012
  • Honorary Professor Healthy Ageing and the Pathobiology of Mammalian Ageing University Medical Center Groningen, Netherlands, 2012
  • Senior Scholar Award in Aging The Ellison Medical Foundation, 2011
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Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • Therapeutic Approaches to Aging—Reply  
    James Kirkland, MD, JAMA
  • Aging, Cell Senescence, and Chronic DiseaseEmerging Therapeutic Strategies  
    James Kirkland, MD, JAMA
  • Senolytics Improve Physical Function and Increase Lifespan in Old Age  
    James L Kirkland, Nathan K LeBrasseur, S John Weroha, Vesna D Garovic, Sundeep Khosla, Allyson K Palmer, Nature
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Books/Book Chapters

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Abstracts/Posters

  • Aging, inflammation and skeletal muscle.
    White TA, Zhu Y, Giorgadze N, Tchkonia T, Kirkland JL, LeBrasseur NK, FASEB J, 1/1/2012
  • Establishment of an in vitro assay for high-throughput screening of pro-adipogenic agents.
    Kling R, Ravuri S, Lin YC, Bechtel J, Gough A, Philips B, Kirkland J, Marra K, Fernstrom J, Rubin P, Journal Of Tissue Engineering And Regenerative Medicine, 1/1/2012
  • Senescent Cells Compromise Fat Tissue Function.
    Xu M, Zhu Y, Pirtskhalava T, Giorgadze N, Baker DJ, Jensen MD, van Deursen J, Tchkonia T, Kirkland JL, J Tissue Eng Regen Med, 1/1/2012
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Lectures

  • Translating Advances from the Basic Biology of Aging into Clinical Application: Opportunities and Challenges 
    Basel, Switzerland - 1/1/2014
  • Obesity, Weight Loss, Diabetes, and Cellular Senescence in Seniors: Opportunities for Intervention 
    Bethesda, MD - 1/1/2014
  • Molecular Basis of Organ Systems Diseases Course (GMSMM-707) 
    Boston University Graduate School, Boston, MA - 1/1/2014
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Other

  • Transgenic Animals Capable of Being Induced to Delete Senescent Cells 
    van Deursen J, Kirkland JL, Tchkonia T, Baker D, US 43613
    1/1/2012
  • Human preadipocyte cell strains and uses therefore. 
    Kirkland JL, Tchkoniai TT, US 31635
    1/1/2002
  • Human adipocyte cell populations and methods for identifying modulators of same. US Provisional Patent 
    Kirkland JL, US 377500
    1/1/2002
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Press Mentions

  • A New Strategy for Fighting Age-Related Disease
    A New Strategy for Fighting Age-Related DiseaseFebruary 8th, 2023
  • Could Getting Rid of Old Cells Turn Back the Clock on Aging?
    Could Getting Rid of Old Cells Turn Back the Clock on Aging?January 2nd, 2023
  • Anti-Aging Drugs Are Being Tested as a Way to Treat Covid
    Anti-Aging Drugs Are Being Tested as a Way to Treat CovidMay 17th, 2022
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Grant Support

  • Cellular Senescence, The Senescent Secretory Phenotype And JAKNational Institute On Aging2012
  • Cellular Senescence And AgingNational Institute On Aging2012
  • Administrative CoreNational Institute On Aging2012
  • Igf-I'S Influence On Pre-AdipocytesNational Institute On Aging2009–2012
  • Effect Of Aging On Preadipocyte DifferentiationNational Institute On Aging2008–2011
  • The Next STEP In Aging Research: From Bench To BedsideNational Institute On Aging2010
  • Igf-I' S Influence On Pre-AdipocytesNational Institute On Aging2010
  • Adipocyte CoreNational Institute Of Diabetes And Digestive And Kidney Diseases2008
  • Regional Differences In Preadipocyte DevelopmentNational Institute On Aging2007
  • Regional Differences In Preadipocyte DevelopmentNational Institute On Aging2003–2007
  • Effect Of Aging On Preadipocyte DifferentiationNational Institute On Aging2001–2005
  • Effect Of Fat Depot Origin On Preadipocyte FunctionNational Institute Of Diabetes And Digestive And Kidney Diseases2000–2004
  • Core--AdipocyteNational Institute Of Diabetes And Digestive And Kidney Diseases1998–2002
  • Aging Effect On Preadipocyte DifferentiationNational Institute On Aging1997–2000
  • Core--AdipocyteNational Institute Of Diabetes And Digestive And Kidney Diseases1997

Committees

  • Mayo Clinic Representative, Association of Directors of Geriatric Academic Programs 2008 - Present
  • Chair Biological Sciences Section, Gerontological Society of America 2011 - 2013

Research History

  • Noaber Foundation Professor of Aging Research - Noaber Foundation,2007 - Present
  • Director - Basic Research Geriatrics Section, Boston University School of Medicine, Boston, Massachusetts1994 - 2007
  • Director of Research - Interdepartmental Division of Geriatrics, University of Toronto, Toronto, Ontario, Canada1988 - 1992