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James Muller, MD, Cardiology, Boston, MA, Brigham and Women's Hospital

JamesEdwardMullerMD

Cardiology • Boston, MA

Cardiothoracic Imaging, Non-Invasive Cardiology, Preventive Cardiology

Cardiologist Brigham and Women’s Hospital Boston, MA

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Summary

  • I am a board certified cardiologist working in the Watkins Clinic of the Shapiro Cardiovascular Center at the Brigham and Women's Hospital, a teaching hospital of the Harvard Medical School.

    My cardiovascular research has centered on the need for better understanding of the pathophysiology of onset of acute coronary syndromes. This work began in 1985 with studies of circadian variation and triggering of coronary events.

    In 1989 with Drs Peter Stone and Geoffrey Tofler, it was proposed that vulnerable coronary plaques might be identified as a means to improve prevention.

    In 1999 I co-founded Infraredx, Inc to build an intracoronary NIR spectroscopy catheter to identify lipid-rich coronary plaques. In 2005, I resigned from my position as Professor of Medicine at the Harvard Medical School to serve as CEO of Infraredx to complete construction of the device and initiate clinical studies.

    In 2015, Infraredx was acquired by Nipro, Inc and I returned to the practice of cardiology after re-training and examination.

    In April, 2019 the US FDA approved the NIRS coronary catheter for the identification of high risk coronary patients and plaques.

    The Infraredx NIRS-IVUS catheter is currently under evaluation in a second large outcome study in Scandinavia for its ability to identify vulnerable plaques and vulnerable patients.

    In other activities, in 1980 I was one of 3 American co-founders of International Physicians for Prevention of Nuclear (IPPNW), the organization awarded the 1985 Nobel Peace Prize. In 2007 IPPNW co-founded the International Campaign to Abolish Nuclear Weapons, which was awarded the 2017 Nobel Peace Prize.

    In 2002 I served as founding president of Voice of the Faithful, a world-wide organization seeking to increase the voice of the Catholic laity as a means to prevent the abuse of children by priests and cover-up of the crimes by church leaders.

Education & Training

  • Brigham and Women's Hospital
    Brigham and Women's HospitalFellowship, Cardiovascular Disease, 1974 - 1975
  • Johns Hopkins University
    Johns Hopkins UniversityResidency, Internal Medicine, 1972 - 1973
  • Johns Hopkins University
    Johns Hopkins UniversityInternship, Internal Medicine, 1969 - 1970
  • Johns Hopkins University School of Medicine
    Johns Hopkins University School of MedicineClass of 1969

Certifications & Licensure

  • MA State Medical License
    MA State Medical License 1973 - 2025
  • KY State Medical License
    KY State Medical License 1997 - 2000
  • American Board of Internal Medicine Internal Medicine
  • American Board of Internal Medicine Cardiovascular Disease

Awards, Honors, & Recognition

  • Fellow (FACC) American College of Cardiology

Clinical Trials

Publications & Presentations

PubMed

Press Mentions

  • Nobel Prize-Winning Cardiologist on His Quest to Find and Treat Vulnerable Plaques
    Nobel Prize-Winning Cardiologist on His Quest to Find and Treat Vulnerable PlaquesMay 8th, 2023
  • American College of Cardiology (ACC) Champions Distinguished Awards Winners at ACC.23/WCC Convocation
    American College of Cardiology (ACC) Champions Distinguished Awards Winners at ACC.23/WCC ConvocationMarch 12th, 2023
  • Combined Imaging Method Overcomes Angiogram Limitations and May Help Prevent Heart Attacks
    Combined Imaging Method Overcomes Angiogram Limitations and May Help Prevent Heart AttacksMarch 12th, 2021
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Grant Support

  • Triggers Of Ventricular Arrhythmias (TOVA) StudyNational Heart, Lung, And Blood Institute1999–2001
  • Modifiers Of Myocardial Infarction OnsetNational Heart, Lung, And Blood Institute1997
  • Modifiers Of Myocardial Infarction OnsetNational Heart, Lung, And Blood Institute1994–1996
  • Determinants Of The Onset Of Myocardial InfarctionNational Heart, Lung, And Blood Institute1990–1992
  • Determinants Of The Onset Of Myocardial InfarctionNational Heart, Lung, And Blood Institute1989

Hospital Affiliations

Dr. James Muller, Dr. James Muller, MD, Dr. J Muller, Dr. James Edward Muller