JamesPaulPirruccelloMD

PubMed

• Artificial Intelligence in Cardiovascular Care - Part 2: Applications: JACC Review Topic of the Week.
  Sneha Jain, Pierre Elias, Timothy Poterucha, Michael Randazzo, Francisco Lopez Jimenez, Rohan Khera, Marco Perez, David Ouyang, James Pirruccello, Michael Salerno, And...> ;Journal of the American College of Cardiology. 2024 Mar 26
• Artificial Intelligence for Cardiovascular Care - Part 1: Advances: JACC Review Topic of the Week.
  Pierre Elias, Sneha Jain, Timothy Poterucha, Michael Randazzo, Francisco Lopez Jimenez, Rohan Khera, Marco Perez, David Ouyang, James Pirruccello, Michael Salerno, And...> ;Journal of the American College of Cardiology. 2024 Mar 26
• 1 citations
  Cardiovascular Significance and Genetics of Epicardial and Pericardial Adiposity.
  Joel T Rämö, Shinwan Kany, Cody R Hou, Samuel F Friedman, Carolina Roselli, Victor Nauffal, Satoshi Koyama, Juha Karjalainen, Mahnaz Maddah, Aarno Palotie, Patrick T E...> ;JAMA Cardiology. 2024 Mar 13
• Using Genomics to Identify Novel Therapeutic Targets for Aortic Disease.
  Raghavan, A., Pirruccello, J., Ellinor, P., Lindsay, M.> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2024 Feb 1
• 1 citations
  Selenoprotein deficiency disorder predisposes to aortic aneurysm formation.
  Schoenmakers, E., Marelli, F., Jørgensen, H., Visser, W., Moran, C., Groeneweg, S., Avalos, C., Jurgens, S., Figg, N., Finigan, A., Wali, N., Agostini, M., Wardle-Jone...> ;Nature Communications. 2023 Dec 2
• Sex differences in ascending aortic size reporting and growth on chest computed tomography and magnetic resonance imaging.
  Siavash Zamirpour, Marko T Boskovski, James P Pirruccello, William A Pace, Alan E Hubbard, Joseph R Leach, Liang Ge, Elaine E Tseng> ;Clinical Imaging. 2024 Jan 1
• Genetically Predicted Gestational Age and Birth Weight Are Associated With Cardiac and Pulmonary Vascular Remodeling in Adulthood.
  Art Schuermans, Maddalena Ardissino, Victor Nauffal, Shaan Khurshid, James P Pirruccello, Patrick T Ellinor, Adam J Lewandowski, Pradeep Natarajan, Michael C Honigberg> ;European Journal of Preventive Cardiology. 2023 Sep 11
• AORTA Gene: Polygenic prediction improves detection of thoracic aortic aneurysm.
  James P Pirruccello, Shaan Khurshid, Honghuang Lin, Weng Lu-Chen, Siavash Zamirpour, Shinwan Kany, Avanthi Raghavan, Satoshi Koyama, Ramachandran S Vasan, Emelia J Ben...> ;Medrxiv. 2023 Aug 25
• 1 citations
  Machine learning-based markers for CAD.
  Amanda Elliott, James P Pirruccello> ;Lancet. 2023 Jul 15
• 6 citations
  Genome-wide association study of thoracic aortic aneurysm and dissection in the Million Veteran Program.
  Derek Klarin, Poornima Devineni, Anoop K Sendamarai, Anthony R Angueira, Sarah E Graham, Ying H Shen, Michael G Levin, James P Pirruccello, Ida Surakka, Purushotham R ...> ;Nature Genetics. 2023 Jul 1
• 3 citations
  Genetic Susceptibility to Atrial Fibrillation Identified via Deep Learning of 12-Lead Electrocardiograms.
  Xin Wang, Shaan Khurshid, Seung Hoan Choi, Samuel Friedman, Lu-Chen Weng, Christopher Reeder, James P Pirruccello, Pulkit Singh, Emily S Lau, Rachael Venn, Nate Diaman...> ;Circulation. Genomic and Precision Medicine. 2023 Aug 1
• 3 citations
  Association of genetic risk and outcomes in patients with atrial fibrillation: interactions with early rhythm control in the EAST-AFNET4 trial.
  Shinwan Kany, Christoph Al-Taie, Carolina Roselli, James P Pirruccello, Katrin Borof, Carla Reinbold, Anna Suling, Linda Krause, Bruno Reissmann, Renate B Schnabel, Ta...> ;Cardiovascular Research. 2023 Aug 7
• 2 citations
  A human FLII gene variant alters sarcomeric actin thin filament length and predisposes to cardiomyopathy.
  Yasuhide Kuwabara, Allen J York, Suh-Chin Lin, Michelle A Sargent, Kelly M Grimes, James P Pirruccello, Jeffery D Molkentin> ;Proceedings of the National Academy of Sciences of the United States of America. 2023 May 9
• 12 citations
  Genetics of myocardial interstitial fibrosis in the human heart and association with disease.
  Victor Nauffal, Paolo Di Achille, Marcus D R Klarqvist, Jonathan W Cunningham, Matthew C Hill, James P Pirruccello, Lu-Chen Weng, Valerie N Morrill, Seung Hoan Choi, S...> ;Nature Genetics. 2023 May 1
• 3 citations
  The Genetic Determinants of Aortic Distention.
  James P Pirruccello, Joel T Rämö, Seung Hoan Choi, Mark D Chaffin, Shinwan Kany, Mahan Nekoui, Elizabeth L Chou, Sean J Jurgens, Samuel F Friedman, Dejan Juric, James ...> ;Journal of the American College of Cardiology. 2023 Apr 11
• 6 citations
  Adjusting for common variant polygenic scores improves yield in rare variant association analyses.
  Sean J Jurgens, James P Pirruccello, Seung Hoan Choi, Valerie N Morrill, Mark Chaffin, Steven A Lubitz, Kathryn L Lunetta, Patrick T Ellinor> ;Nature Genetics. 2023 Apr 1
• 3 citations
  Clinical and genetic associations of deep learning-derived cardiac magnetic resonance-based left ventricular mass.
  Shaan Khurshid, Julieta Lazarte, James P Pirruccello, Lu-Chen Weng, Seung Hoan Choi, Amelia W Hall, Xin Wang, Samuel F Friedman, Victor Nauffal, Kiran J Biddinger, Kri...> ;Nature Communications. 2023 Mar 21
• 10 citations
  Genetics and mechanisms of thoracic aortic disease.
  Elizabeth Chou, James P Pirruccello, Patrick T Ellinor, Mark E Lindsay> ;Nature Reviews. Cardiology. 2023 Mar 1
• 21 citations
  Predictive Utility of a Coronary Artery Disease Polygenic Risk Score in Primary Prevention.
  Nicholas A Marston, James P Pirruccello, Giorgio E M Melloni, Satoshi Koyama, Frederick K Kamanu, Lu-Chen Weng, Carolina Roselli, Yoichiro Kamatani, Issei Komuro, Kris...> ;JAMA Cardiology. 2023 Feb 1
• 19 citations
  mediated clonal hematopoiesis confers increased risk for incident atherosclerotic disease.
  Seyedeh M Zekavat, Vanesa Viana-Huete, Nuria Matesanz, Saman Doroodgar Jorshery, María A Zuriaga, Md Mesbah Uddin, Mark Trinder, Kaavya Paruchuri, Virginia Zorita, Alb...> ;Nature Cardiovascular Research. 2023 Jan 16
• 5 citations
  Development of a Prediction Model for Ascending Aortic Diameter Among Asymptomatic Individuals.
  James P Pirruccello, Honghuang Lin, Shaan Khurshid, Mahan Nekoui, Lu-Chen Weng, Ramachandran S Vasan, Eric M Isselbacher, Emelia J Benjamin, Steven A Lubitz, Mark E Li...> ;JAMA. 2022 Nov 15
• 8 citations
  Aortic Cellular Diversity and Quantitative Genome-Wide Association Study Trait Prioritization Through Single-Nuclear RNA Sequencing of the Aneurysmal Human Aorta.
  Elizabeth L Chou, Mark Chaffin, Bridget Simonson, James P Pirruccello, Amer-Denis Akkad, Mahan Nekoui, Christian Lacks Lino Cardenas, Kenneth C Bedi Jr, Craig Nash, De...> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2022 Nov 1
• Publisher Correction: Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes.
  Jennifer L Halford, Valerie N Morrill, Seung Hoan Choi, Sean J Jurgens, Giorgio Melloni, Nicholas A Marston, Lu-Chen Weng, Victor Nauffal, Amelia W Hall, Sophia Gunn, ...> ;Nature Communications. 2022 Sep 30
• 9 citations
  Wearable accelerometer-derived physical activity and incident disease.
  Shaan Khurshid, Lu-Chen Weng, Victor Nauffal, James P Pirruccello, Rachael A Venn, Mostafa A Al-Alusi, Emelia J Benjamin, Patrick T Ellinor, Steven A Lubitz> ;NPJ Digital Medicine. 2022 Sep 2
• 2 citations
  Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes.
  Jennifer L Halford, Valerie N Morrill, Seung Hoan Choi, Sean J Jurgens, Giorgio Melloni, Nicholas A Marston, Lu-Chen Weng, Victor Nauffal, Amelia W Hall, Sophia Gunn, ...> ;Nature Communications. 2022 Aug 30
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Lectures

• Future HubAre Clinical Virtual Reality and Augmented Reality Ready for Prime Time? 
  2019 ACC Scientific Session & Expo, New Orleans - 3/16/2019