JamesThomasMDFAAP

PubMed

• 1 citations
  Use of Berlin EXCOR cannulas in both venovenous and venoarterial central extracorporeal membrane oxygenation configurations overcomes the problem of cannula instabilit...
  N Adam Stephens, Corey A Chartan, Maria C Gazzaneo, James A Thomas, Shailendra Das, George B Mallory Jr, Ernestina Melicoff, Adam M Vogel, Amanda Parker, Emily Hermes,...> ;JTCVS Techniques. 2023 Apr 1
• 7 citations
  Central venoarterial extracorporeal life support in pediatric refractory septic shock: a single center experience.
  Amanda Ruth, Adam M. Vogel, Iki Adachi, Lara S. Shekerdemian, Patricia Bastero, James A. Thomas> ;Perfusion. 2021 Mar 15
• 11 citations
  Outcomes After Extracorporeal Life Support Cannulation in Pediatric Patients With Trisomy 13 and Trisomy 18
  Elizabeth A. Alore, Sara C. Fallon, James A. Thomas, Adam M. Vogel> ;The Journal of Surgical Research. 2021 Jan 1
• 24 citations
  Extracorporeal Membrane Oxygenation Mortality in High-Risk Populations: An Analysis of the Pediatric Health Information System Database.
  Ryan D. Coleman, Jordana Goldman, Brady S. Moffett, Danielle Guffey, Laura Loftis, James W. Thomas, Lara S. Shekerdemian> ;ASAIO Journal. 2020 Mar 1
• 12 citations
  Extracorporeal Cardiopulmonary Resuscitation After Diphenhydramine Ingestion.
  Sonia Labarinas, Kristen Meulmester, Spencer Greene, James W. Thomas, Manpreet Virk, Gwen Erkonen> ;Journal of Medical Toxicology. 2018 Jun 28
• 36 citations
  Use of venovenous ECMO for neonatal and pediatric ECMO: a decade of experience at a tertiary children’s hospital
  Jennifer L. Carpenter, Yangyang R. Yu, Darrell L. Cass, Oluyinka O. Olutoye, James A. Thomas, Cole Burgman, Caraciolo J. Fernandes, Timothy C. Lee> ;Pediatric Surgery International. 2018 Jan 18
• 13 citations
  Evaluating quality of life of extracorporeal membrane oxygenation survivors using the pediatric quality of life inventory survey
  Yangyang R. Yu, Jennifer L. Carpenter, Annalyn S. DeMello, Sundeep G. Keswani, Darrell L. Cass, Oluyinka O. Olutoye, Adam M. Vogel, James A. Thomas, Cole Burgman, Cara...> ;Journal of Pediatric Surgery. 2018 May 1
• 201 citations
  IRAK-1 bypasses priming and directly links TLRs to rapid NLRP3 inflammasome activation.
  Keng-Mean Lin, Wei Hu, Ty D. Troutman, Michelle Jennings, Travis Brewer, Xiaoxia Li, Sambit K. Nanda, Philip Cohen, James A. Thomas, Chandrashekhar Pasare> ;Proceedings of the National Academy of Sciences of the United States of America. 2014 Jan 14
• 100 citations
  IRAK-M mediates Toll-like receptor/IL-1R-induced NFκB activation and cytokine production
  Hao Zhou, Minjia Yu, Koichi Fukuda, Jinteak Im, Peng Yao, Wei Cui, Katarzyna Bulek, Jarod A. Zepp, Youzhong Wan, Tae Whan Kim, Weiguo Yin, Victoria Ma, James A. Thomas...> ;The EMBO Journal. 2013 Feb 20
• 27 citations
  IRAK1-Dependent Signaling Mediates Mortality in Polymicrobial Sepsis
  Rachna Chandra, Stephanie Federici, Tripti Bishwas, Zoltán Németh, Edwin A. Deitch, James A. Thomas, Zoltán Spolarics> ;Inflammation. 2013 Jul 16
• 21 citations
  Interleukin-1 Receptor-Associated Kinase-2 (IRAK2) Is a Critical Mediator of Endoplasmic Reticulum (ER) Stress Signaling
  Samir Benosman, Palaniyandi Ravanan, Ricardo G. Correa, Ying Chen Hou, Minjia Yu, Muhammet F. Gulen, Xiaoxia Li, James A. Thomas, Michael Cuddy, Yasuko Matsuzawa, Rena...> ;Plos One. 2013 May 28
• 60 citations
  Donation after cardiocirculatory death: a call for a moratorium pending full public disclosure and fully informed consent
  Ari R. Joffe, J. Carcillo, Natalie Anton, Allan DeCaen, Yong Y. Han, Michael J. Bell, Frank A. Maffei, John S. Sullivan, James A. Thomas, Gonzalo Garcia-Guerra> ;Philosophy, Ethics, and Humanities in Medicine. 2011 Dec 29
• 21 citations
  The Dual Functions of IL-1 Receptor-Associated Kinase 2 in TLR9-Mediated IFN and Proinflammatory Cytokine Production
  Youzhong Wan, Tae Whan Kim, Minjia Yu, Hao Zhou, Michifumi Yamashita, Zizhen Kang, Weiguo Yin, Jian An Wang, James A. Thomas, Ganes C. Sen, George Stark Stark, Xiaoxia Li> ;Journal of Immunology. 2011 Mar 1
• 16 citations
  A call for full public disclosure and moratorium on donation after cardiac death in children.
  Joseph A. Carcillo, Richard A. Orr, Michael J. Bell, Ari R. Joffe, Frank A. Maffei, John S. Sullivan, Yong Y. Han, James A. Thomas> ;Pediatric Critical Care Medicine. 2010 Sep 1
• Farewell to innocence: untangling septic shock in the postgenomic era.
  Octavio Ramilo, James A. Thomas> ;Pediatric Critical Care Medicine. 2010 May 1
• 13 citations
  Age-dependent differences of interleukin-6 activity in cardiac function after burn complicated by sepsis
  Lin Wang, Jiexia Quan, William E. Johnston, David L. Maass, Jureta W. Horton, James A. Thomas, Weike Tao> ;Burns. 2010 Mar 1
• 39 citations
  Innate immunity mediates myocardial preconditioning through Toll-like receptor 2 and TIRAP-dependent signaling pathways
  Jian-Wen Dong, Jesus G. Vallejo, Huei Ping Tzeng, James A. Thomas, Douglas L. Mann> ;American Journal of Physiology. Heart and Circulatory Physiology. 2010 Mar 1
• 143 citations
  Outcomes among neonates, infants, and children after extracorporeal cardiopulmonary resuscitation for refractory inhospital pediatric cardiac arrest: a report from the...
  Tia T Raymond, Christopher B. Cunnyngham, Marita Thompson, James A. Thomas, Heidi J. Dalton, Vinay M. Nadkarni> ;Pediatric Critical Care Medicine. 2009 Nov 1
• 3 citations
  Recognizing, understanding, and treating critical community acquired methicillin-resistant Staphylococcus aureus infection in children.
  Joseph A. Carcillo, Leticia Castillo, James A. Thomas, Niranjan Kissoon> ;Pediatric Critical Care Medicine. 2009 May 1
• 56 citations
  PDGF-DD, a novel mediator of smooth muscle cell phenotypic modulation, is upregulated in endothelial cells exposed to atherosclerosis-prone flow patterns
  James A. Thomas, Rebecca A. Deaton, Nicole E. Hastings, Yueting Shang, Christopher W. Moehle, Ulf Eriksson, Stavros Topouzis, Brian R. Wamhoff, Brett R. Blackman, Gary...> ;American Journal of Physiology. Heart and Circulatory Physiology. 2009 Feb 1
• 13 citations
  Gender dependent importance of IRAK-1 in dextran sulfate sodium induced colitis.
  Martin Berglund, James A. Thomas, Maria Fritsch Fredin, Silvia Melgar, Elisabeth Hultgren Hörnquist, Olof H. Hultgren> ;Cellular Immunology. 2009 Jan 1
• 71 citations
  Interleukin-1 receptor-associated kinase 2 is critical for lipopolysaccharide-mediated post-transcriptional control.
  Youzhong Wan, Hui Xiao, Jeremy Affolter, Tae Whan Kim, Katarzyna Bulek, Sujan Chaudhuri, Deborah Carlson, Thomas A. Hamilton, Barsanjit Mazumder, George R. Stark, Jame...> ;The Journal of Biological Chemistry. 2009 Apr 17
• 184 citations
  Lys63-Linked Polyubiquitination of IRAK-1 Is Required for Interleukin-1 Receptor- and Toll-Like Receptor-Mediated NF-κB Activation
  Dietrich B. Conze, Chuan Jin Wu, James A. Thomas, Allison Landstrom, Jonathan D. Ashwell> ;Molecular and Cellular Biology. 2008 May 15
• 11 citations
  Toll-like receptor cross-hyporesponsiveness is functional in interleukin-1-receptor-associated kinase-1 (IRAK-1)-deficient macrophages: differential role played by IRA...
  Martin Berglund, James A. Thomas, Elisabeth Hultgren Hörnquist, Olof H. Hultgren> ;Scandinavian Journal of Immunology. 2008 May 1
• 47 citations
  FADD Negatively Regulates Lipopolysaccharide Signaling by Impairing Interleukin-1 Receptor-Associated Kinase 1-MyD88 Interaction
  Rachel Zhande, Shauna M. Dauphinee, James A. Thomas, Masahiro Yamamoto, Shizuo Akira, Aly Karsan> ;Molecular and Cellular Biology. 2007 Nov 1
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Journal Articles

• Bleeding and Thrombotic Complications in the Use of Extracorporeal Membrane Oxygenation  
  Thomas J, Kostousov V, Teruya J, Semin Thromb Hemost, 1/1/2018
• The authors reply  
  Sheeran PD, Anton-Martin P, Thompson MT, Fischer AC, Taylor D, Thomas JA, Pediatr Crit Care Med, 1/1/2015
• Cellular mosaicism for X-linked polymorphisms and IRAK1 expression presents a distinct phenotype and improves survival following sepsis  
  Chandra R, Federici S, Nemeth ZH, Csoka B, Thomas JA, Donnelly R, Spolarics Z, Journal of Leukocyte Biology, 1/1/2014
• Extubation during Pediatric Extracorporeal Membrane Oxygenation (ECMO): a single center experience  
  Anton-Martin P, Thompson MT, Sheeran PD, Fischer A, Taylor D, Thomas JA, Pediatric Critical Care Medicine, 1/1/2014
• IKKalpha negatively regulates ASC-dependent inflammasome activation  
  Martin BN, Wang C, Willette-Brown J, Herjan T, Gulen MF, Zhou H, Bulek K, Franchi L, Sato T, Alnemri ES, Narla G, Zhong XP, Thomas J, Klinman D, Fitzgerald KA, Karin M..., Nat Commun, 1/1/2014
• Understanding family requirements in the intensive care room  
  Evans, J, Thomas, J, Critical Care Nursing Quarterly, 1/1/2011
• Outcomes among Neonates, Infants and Children After Extracorporeal Cardiopulmonary Resuscitation for Refractory In-hospital Pediatric Cardiac Arrest: A Report from th...  
  Raymond TT, Cunnyngham CB, Thompson MT, Thomas JA, Dalton HJ, Nadkarni VM, for the American Heart Association National Registry of CPR Investigators, Pediatr Crit Care Med, 1/1/2010
• A call for full public disclosure and moratorium on donation after cardiac death in children  
  Carcillo JA, Orr R, Bell M, Joffe A, Maffei FA, Sullivan J, Han YY, Thomas J, Pediatr Crit Care Med, 1/1/2010
• Farewell to innocence: Untangling septic shock in the post-genomic era (Editorial)  
  Ramilo O, Thomas JA, Pediatr Crit Care Med, 1/1/2010
• Identification of IRAK1 as a risk gene with a critical role in the pathogenesis of Systemic Lupus Erythematosus  
  Jacob CO, Zhua Z, Armstrong DL, Yan M, Han J, Zhou J, Thomas JA, Reiff A, Myone BL, Ojwang JO, Kaufman KM, Klein-Gitelman M, McCurdy D, Wagner-Weiner L, Silverman E, Z..., Proc Natl Acad Sci U S A, 1/1/2009
• Recognizing, understanding and treating critical community-acquired MRSA infection in children (Editorial)  
  Carcillo JA, Castillo L, Thomas J, Kissoon N, Pediatr Crit Care Med, 1/1/2009
• Age-Dependent Differences in the Effect of Interleukin-6 Deficiency in Cardiac Function after Burn Complicated by Sepsis  
  Wang L, Quan J, Johnston WE, Maass DL, Horton JW, Thomas JA, Tao W, Burns, 1/1/2009
• Toll-like receptor cross-hyporesponsiveness is functional in interleukin-1-receptor-associated kinase-1 (IRAK-1)-deficient macrophages: differential role played by IRA...  
  Berglund M, Thomas JA, H�rnquist EH, Hultgren OH, Scandinavian Journal of Immunology, 1/1/2008
• FADD negatively regulated lipopolysaccharide signaling by impairing interleukin-1 receptor-associated kinase 1-MyD88 interaction  
  Zhande R. Dauphinee SM, Thomas JA, Tamamoto M, Akira S, Karsan, A, Molecular and Cellular Biology, 1/1/2007
• Innate stimuli accentuate end-organ damage by nephrotoxic antibodies via Fc receptor and TLR stimulation and IL-1/TNF-alpha production  
  Fu Y, Xie C, Chen J, Zhu J, Zhou H, Thomas J, Zhou XJ, Mohan C, Journal of Immunology, 1/1/2006
• Multiple toll-like receptor agonists act as potent adjuvants in the induction of autoimmunity  
  Hansen BS, Hussain RZ, Lovett-Racke AE, Thomas JA, Racke MK, Journal of Neuroimmunol, 1/1/2006
• Differential induction of apoptosis by LPS and Taxol in monocytic cells  
  Li, T, J Hu, JA Thomas, L Li, Molecular Immunology, 1/1/2005
• Selective decontamination of the digestive tract attenuated the myocardial inflammation and dysfunction that occur with burn injury  
  Horton, JW, J Tan, D. J White, DL Maass, and JA Thomas, American Journal of Physiology: Heart and Circulatory Physiology, 1/1/2004
• IRAK deletion disrupts cardiac Toll/IL-1 signaling and prevents against contractile dysfunction  
  Thomas, JA, SB Haudek, TF Koroglu, MF Tsen, DD Bryant, DJ White, DF Kusewitt, JW Horton, BP Giroir, American Journal of Physiology: Heart and Circulatory Physiology, 1/1/2003
• IRAK contributes to burn-induced myocardial contractile dysfunction  
  Thomas, JA, MF Tsen, J White, J Horton, American Journal of Physiology: Heart and Circulatory Physiology, 1/1/2002
• Toll genes and responsiveness to bacterial endotoxin [letter]  
  Thomas JA, New England Journal of Medicine, 1/1/2000
• Successful treatment of myocarditis with severe dysrhythmias in infants with respiratory syncytial virus infections: two cases and a literature review  
  Thomas, JA, S Raroque, WA Scott, LO Toro-Figueroa, DL Levin, Critical Care Medicine, 1/1/1997
• Human Hsp70 Protects Murine Cells from Injury During Metabolic Stress  
  Williams, RS, JA Thomas, M Fina, Z German, IJ Benjamin, Journal of Clinical Investigation, 1/1/1993
• Effects of Elevated Serum Insulinlike Growth Factor-II on Growth Hormone and Insulinlike Growth Factor-I mRNA and Secretion  
  Wilson, DM, SN Perkins, JA Thomas, S Seelig, SA Berry, TA Hamm, AR Hoffman, RL Hintz, RG Rosenfeld, Metabolism, 1/1/1989
• The Ethical Use of Human Fetal Tissue in Medicine  
  Greely, HT, TE Hamm, R Johnson, CR Price, R Weingarten, TA Raffin, and The Stanford University Medical Center Committee on Ethics, New ngland Journal of Medicine, 1/1/1989
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Books/Book Chapters

• Rudolph�s Pediatrics 
  Chapter: Chapter 108: Extracorporeal Membrane Oxygenation. 
  Bastero P, Thomas JAEditors: Kline, M.McGraw-Hill EducationEdition 23rd,2018
• Rogers� Textbook of Pediatric Intensive Care 
  Chapter: Chapter 19. Inflammation and Innate Immunity (Chapter revision) 
  Page 225 - 239Thomas, JAEdition 5th,2015
• Rogers� Textbook of Pediatric Intensive Care 
  Chapter: Inflammation and Innate Immunity 
  Page 224 - 240Thomas JAEditors: Nichols, DG.Lippincott Williams & Wilkins, Philadelphia, PAEdition 4th,2008
• Essentials of Pediatric Intensive Care 
  Chapter: Molecular Intensive Care 
  Page 239 - 265Thomas JAEditors: Levin DL and Morriss FC.Churchill Livingstone, Inc., New York, NYEdition 2nd,1997
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Lectures

• Law, Literature and Medicine 
  Multiple Dates and Locations - 1/1/2013
• Case Studies in Immunology: Bacterial Infections 
  Multiple Dates - 1/1/2012
• Science Citizenship - Media and Policy 
  Multiple Dates - 1/1/2011
• Global Health in 2020 
  1/1/2009
• Sepsis, Resuscitation, and New Frontiers in Pediatric Critical Care 
  Dartmouth Hitchcock Medical Center, Lebanon, NH - 1/1/2007
• The Toll/IL-1 Signaling Pathway 
  Multiple Dates - 1/1/2006
• IRAK Signaling 
  Phoenix, AZ - 1/1/2005
• Presente y Futuro de la Biolog�a Molecular en la Sepsis 
  Bogota, Colombia - 1/1/2004
• Que Hay de Nuevo � y No Tan Nuevo � en la Sepsis y el Shock Septico? 
  Bogota, Colombia - 1/1/2004
• New�and Not-So-New�Perspectives in Pediatric Septic Shock 
  Cartagena, Colombia - 1/1/2003
• Toll/IL-1 Signal Transduction: Universal Mechanism of Immune Surveillance 
  Cartagena, Colombia - 1/1/2003
• Innate Response to Infection 
  1/1/2003
• Bugs, Bombs and Self-Flagellation: Toll/IL-1 Signaling and the 23rd Psalm 
  UT Southwestern Medical Center, Dallas, TX - 1/1/2002
• Host Defense Against Infection: Inflammation 
  1/1/2002
• Toll/IL-1 signaling in shock-induced cardiac dysfunction: exploring the interface between innate immunity and nonimmune phsiology 
  Marco Island, FL - 1/1/2001
• Embryonic Stem Cells and Genomic Manipulation 
  1/1/2000
• IRAK in immune and nonimmune signaling: the Toll/IL-1 pathway demarcates the host response to infection 
  Munich, Germany - 1/1/2000
• IRAK and Toll/IL-1 Signaling: A Critical Link in the Host Response to Injury and Infection 
  1/1/1999
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Other

• U.S. Congress Office of Technology Assessment, Alternatives to Animal Use in Research, Testing, and Education 
  Thomas JA, Government Printing Office
  1/1/1986
• U.S. Congress Office of Technology Assessment, Commercial Biotechnology: An International Analysis, U.S. 
  Thomas JA, Government Printing Office
  1/1/1984
• U.S. Congress Office of Technology Assessment, Impacts of Neuroscience 
  Thomas JA, Government Printing Office
  1/1/1984
• senior thesis: La Dualidad �Yo-El� de Yo el Supremo de Augusto Roa Bastos 
  Thomas JA
  Princeton University, Princeton, NJ - 1/1/1981
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