JasonAnthonyHethMD

Neurosurgery • Ann Arbor, MI

Associate Professor of Neurological Surgery, University Mich Medical School

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Office
1500 East Medical Center Dr
2nd Floor Taubman Ctr Recp G
Ann Arbor, MI 48109
Phone+1 734-330-1993
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Education & Training

University of Iowa Hospitals and ClinicsResidency, Neurological Surgery, 1996 - 2002
University of Iowa Roy J. and Lucille A. Carver College of MedicineClass of 1996

Certifications & Licensure

MI State Medical License 2003 - 2025
AR State Medical License 2002 - 2010
IA State Medical License 1996 - 2009
American Board of Neurological Surgery Neurological Surgery

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012
Fellow (FAANS) American Association of Neurological Surgeons
Fellow (FACS) American College of Surgeons
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Clinical Trials

Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer Start of enrollment: 2006 Dec 01
Active, not recruiting
Phase 3

Publications & Presentations

PubMed

2 citations
Metabolomic Profiles of Human Glioma Inform Patient Survival.
Andrew J Scott, Luis O Correa, Donna M Edwards, Yilun Sun, Visweswaran Ravikumar, Anthony C Andren, Li Zhang, Sudharsan Srinivasan, Neil Jairath, Kait Verbal, Karin Mu...> ;Antioxidants & Redox Signaling. 2023 Nov 1
7 citations
Combined cytotoxic and immune-stimulatory gene therapy for primary adult high-grade glioma: a phase 1, first-in-human trial.
Yoshie Umemura, Daniel Orringer, Larry Junck, Maria L Varela, Molly E J West, Syed M Faisal, Andrea Comba, Jason Heth, Oren Sagher, Denise Leung, Aaron Mammoser, Shawn...> ;The Lancet. Oncology. 2023 Sep 1
Optimizing Precision Medicine for Breast Cancer Brain Metastases with Functional Drug Response Assessment.
Aki Morikawa, Jinju Li, Peter Ulintz, Xu Cheng, Athena Apfel, Dan Robinson, Alex Hopkins, Chandan Kumar-Sinha, Yi-Mi Wu, Habib Serhan, Kait Verbal, Dafydd Thomas, Dani...> ;Cancer Research Communications. 2023 Jun 1
Milestones for neurosurgery sub-interns: a novel evaluation tool to quantitatively differentiate residency applicants.
Stephen G Bowden, Hao Tan, Michael G Rothbaum, Steven H Cook, Simon Hanft, Jason Heth, Peter F Morgenstern, Jeffrey P Mullin, Josiah N Orina, Jonathan L Wilson, Jesse ...> ;Journal of Neurosurgery. 2023 Dec 1
25 citations
Artificial-intelligence-based molecular classification of diffuse gliomas using rapid, label-free optical imaging.
Todd Hollon, Cheng Jiang, Asadur Chowdury, Mustafa Nasir-Moin, Akhil Kondepudi, Alexander Aabedi, Arjun Adapa, Wajd Al-Holou, Jason Heth, Oren Sagher, Pedro Lowenstein...> ;Nature Medicine. 2023 Apr 1
1 citations
Subclonal evolution and expansion of spatially distinct THY1-positive cells is associated with recurrence in glioblastoma.
Wajd N Al-Holou, Hanxiao Wang, Visweswaran Ravikumar, Sunita Shankar, Morgan Oneka, Ziad Fehmi, Roel Gw Verhaak, Hoon Kim, Drew Pratt, Sandra Camelo-Piragua, Corey Spe...> ;Neoplasia. 2023 Feb 1
1 citations
Commentary: An Examination of Standardized Letters of Recommendation Rating Scales Among Neurosurgical Residency Candidates During the 2020 to 2021 Application Cycle.
Jason Heth, Stacey Q Wolfe> ;Neurosurgery. 2021 Nov 18
21 citations
Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas.
Pooja Panwalkar, Benita Tamrazi, Derek Dang, Chan Chung, Stefan Sweha, Siva Kumar Natarajan, Matthew Pun, Jill Bayliss, Martin P. Ogrodzinski, Drew Pratt, Brendan Mull...> ;Science Translational Medicine. 2021 Oct 6
44 citations
G-CSF secreted by mutant IDH1 glioma stem cells abolishes myeloid cell immunosuppression and enhances the efficacy of immunotherapy.
Mahmoud S. Alghamri, Brandon L. McClellan, Ruthvik Avvari, Rohit Thalla, Stephen Carney, Margaret S. Hartlage, Santiago Haase, Maria Ventosa, Ayman Taher, Neha Kamran,...> ;Science Advances. 2021 Sep 29
1 citations
A customized 3D implant to target laser interstitial thermal therapy ablation of a posterior fossa mass.
Julia E. Kozlowski, Kyle K. VanKoevering, Jason Heth> ;Journal of Clinical Neuroscience. 2021 Aug 1
1 citations
Introduction to special issue dedicated to the 35th anniversary of the joint section on tumors.
Isabelle M. Germano, Jason Heth, Pamela S. Jones, Manish K. Aghi> ;Journal of Neuro-Oncology. 2021 Feb 1
21 citations
Rapid, label-free detection of diffuse glioma recurrence using intraoperative stimulated Raman histology and deep neural networks.
Todd C. Hollon, Balaji Pandian, Esteban Urias, Akshay V. Save, Arjun R. Adapa, Sudharsan Srinivasan, Neil K. Jairath, Zia Farooq, Tamara Marie, Wajd N. Al-Holou, Karen...> ;Neuro-Oncology. 2021 Jan 30
16 citations
A Phase 2 Study of Dose-intensified Chemoradiation Using Biologically Based Target Volume Definition in Patients With Newly Diagnosed Glioblastoma
Michelle M. Kim, Yilun Sun, Madhava P. Aryal, Hemant Parmar, Morand Piert, B.S. Rosen, Charles S. Mayo, James M. Balter, Matthew J. Schipper, Nicolette Gabel, Emily M....> ;International Journal of Radiation Oncology, Biology, Physics. 2020 Nov 1
5 citations
Utilization of a Resuscitative Care Unit for Initial Triage, Management, and Disposition of Minor Intracranial Hemorrhage.
Jacob R. Joseph, Nathan L. Haas, John R Joseph, Jason Heth, Nicholas J. Szerlip, Benjamin S. Bassin> ;Critical Care Explorations. 2020 Apr 29
284 citations
Near real-time intraoperative brain tumor diagnosis using stimulated Raman histology and deep neural networks
Todd C. Hollon, Balaji Pandian, Arjun R. Adapa, Esteban Urias, Akshay V. Save, Siri Sahib S Khalsa, Daniel G Eichberg, Randy S. D'Amico, Zia Farooq, Spencer Lewis, Pet...> ;Nature Medicine. 2020 Jan 6
10 citations
Outcomes in Patients Treated with Laser Interstitial Thermal Therapy for Primary Brain Cancer and Brain Metastases
Leigh Klaus Swartz, Katherine Holste, Michelle M. Kim, Aki Morikawa, Jason Heth> ;The Oncologist. 2019 Dec 1
4 citations
Thirty-Day Hospital Readmission and Surgical Complication Rates for Shunting in Normal Pressure Hydrocephalus: A Large National Database Analysis.
Jeffrey L Nadel, D Andrew Wilkinson, Joseph R Linzey, Cormac O Maher, Vikas Kotagal, Jason A Heth> ;Neurosurgery. 2020 Jun 1
9 citations
Dose-intensified chemoradiation is associated with altered patterns of failure and favorable survival in patients with newly diagnosed glioblastoma.
Michelle M. Kim, Corey Speers, Pin Li, Matthew J. Schipper, Larry Junck, Denise Leung, Daniel A. Orringer, Jason Heth, Yoshie Umemura, Daniel E. Spratt, Daniel R. Wahl...> ;Journal of Neuro-Oncology. 2019 Apr 11
20 citations
A platform for artificial intelligence based identification of the extravasation potential of cancer cells into the brain metastatic niche.
C. Ryan Oliver, Megan Altemus, Trisha M. Westerhof, Hannah Cheriyan, Xu Cheng, Michelle Dziubinski, Zhifen Wu, Joel A. Yates, Aki Morikawa, Jason Heth, Maria G. Castro...> ;Lab on a Chip. 2019 Mar 27
45 citations
CSF H3F3A K27M circulating tumor DNA copy number quantifies tumor growth and in vitro treatment response
Stefanie Stallard, Masha G. Savelieff, Kyle Wierzbicki, Brendan Mullan, Zachary Miklja, Amy K. Bruzek, Taylor Garcia, Ruby Siada, Bailey Anderson, Benjamin H. Singer, ...> ;Acta Neuropathologica Communications. 2018 Aug 15
13 citations
Clinical Factors Associated With ICU-Specific Care Following Supratentoral Brain Tumor Resection and Validation of a Risk Prediction Score.
Lynze R. Franko, Todd C. Hollon, Joseph R Linzey, Christopher Roark, Venkatakrishna Rajajee, Kyle M. Sheehan, Magnus K. Teig, Shawn L. Hervey-Jumper, Jason Heth, Danie...> ;Critical Care Medicine. 2018 Aug 1
9 citations
Correction: First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma [J Transl Med., 16, (...
Linda M. Liau, Keyoumars Ashkan, David Tran, Jian Campian, John E. Trusheim, Charles S. Cobbs, Jason Heth, Michael Salacz, Sarah A. Taylor, Stacy D. D’Andre, Fabio M. ...> ;Journal of Translational Medicine. 2018 Jun 29
167 citations
First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma.
Linda M Liau, Keyoumars Ashkan, David D Tran, Jian L Campian, John E Trusheim, Charles S Cobbs, Jason A Heth, Michael Salacz, Sarah Taylor, Stacy D D'Andre, Fabio M Iw...> ;Journal of Translational Medicine. 2018 May 29
6 citations
Serious adverse events following Normal Pressure Hydrocephalus surgery.
Vikas Kotagal, Elizabeth Walkowiak, Jason Heth> ;Clinical Neurology and Neurosurgery. 2018 Jul 1
4 citations
Standard dose and dose-escalated radiation therapy are associated with favorable survival in select elderly patients with newly diagnosed glioblastoma
William C. Jackson, Christina I. Tsien, Larry Junck, Denise Leung, Shawn L. Hervey-Jumper, Daniel A. Orringer, Jason Heth, Daniel R. Wahl, Daniel E. Spratt, Yue Cao, T...> ;Journal of Neuro-Oncology. 2018 Feb 1
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