JeanBBelascoMD

Pediatric Hematology & Oncology • Philadelphia, PA

Professor, Pediatrics, Perelman School of Medicine

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Office
3401 Civic Center Blvd
Children's Hospital Of Philadelphia - Hem/Onc
Philadelphia, PA 19104
Phone+1 215-590-3535

Fax+1 215-590-3992
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Education & Training

Children's Hospital of PhiladelphiaFellowship, Pediatric Hematology/Oncology, 1978 - 1980
Tower Health/St. Christopher's Hospital for ChildrenResidency, Pediatrics, 1973 - 1976
Lewis Katz School of Medicine at Temple UniversityClass of 1973

Certifications & Licensure

PA State Medical License 1975 - 2024
NJ State Medical License 1997 - 2011
DE State Medical License 1996 - 2011
NC State Medical License 1976 - 1980
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Hematology-Oncology

Clinical Trials

Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas Start of enrollment: 2001 Feb 01
Completed
Phase 2
Paclitaxel Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma Start of enrollment: 1999 Aug 01
Terminated
Phase 1

Publications & Presentations

PubMed

Vinblastine/Methotrexate for Debilitating and Progressive Plexiform Neurofibroma in Children and Young Adults with Neurofibromatosis Type 1: A Phase 2 Study.
Chelsea Kotch, Kristina Wagner, J Harris Broad, Eva Dombi, Jane E Minturn, Peter Phillips, Katherine Smith, Yimei Li, Ian N Jacobs, Lisa M Elden, Michael J Fisher, Jea...> ;Cancers. 2023 May 5
4 citations
A Pilot Study of Low-Dose Craniospinal Irradiation in Patients With Newly Diagnosed Average-Risk Medulloblastoma.
Jane E. Minturn, Aaron Y Mochizuki, Sonia Partap, Jean B. Belasco, Beverly J. Lange, Yimei Li, Peter C. Phillips, Iris C. Gibbs, Paul G. Fisher, Michael Fisher, Anna J...> ;Frontiers in Oncology. 2021 Sep 2
2 citations
MRI for Response Assessment of Extensive Lymphatic Malformations in Children Treated With Sirolimus.
Rachelle Durand, Janet R. Reid, Jean B. Belasco, Sphoorti Shellikeri, Juan S. Calle-Toro, Anne Marie Cahill, Abhay Srinivasan> ;AJR. American Journal of Roentgenology. 2021 Jan 6
49 citations
Severe Lymphatic Disorder Resolved With MEK Inhibition in a Patient With Noonan Syndrome and SOS1 Mutation.
Yoav Dori, Chris Smith, Erin Pinto, Kristen M. Snyder, Michael E. March, Hakon Hakonarson, Jean B. Belasco> ;Pediatrics. 2020 Nov 1
5 citations
Tumor bed proton irradiation in young children with localized medulloblastoma.
Amardeep S. Grewal, Yimei Li, Michael Fisher, Jane E. Minturn, Iris Paltin, Jean B. Belasco, Peter C. Phillips, Tammy I. Kang, Robert A. Lustig, Christine E. Hill-Kayser> ;Pediatric Blood & Cancer. 2019 Dec 1
13 citations
Risk of brainstem necrosis in pediatric patients with central nervous system malignancies after pencil beam scanning proton therapy
J. Vogel, A. Grewal, Shannon O'Reilly, Robert A. Lustig, G. Kurtz, Jane E. Minturn, Amish C. Shah, Angela J. Waanders, Jean B. Belasco, Kristina A. Cole, Michael Fishe...> ;Acta Oncologica. 2019 Sep 12
108 citations
ARAF recurrent mutation causes central conducting lymphatic anomaly treatable with a MEK inhibitor
Dong Li, Michael E. March, Alvaro Gutierrez-Uzquiza, Charlly Kao, Christoph Seiler, Erin Pinto, Leticia S. Matsuoka, Mark R Battig, Elizabeth J. Bhoj, Tara L. Wenger, ...> ;Nature Medicine. 2019 Jul 1
4 citations
Primary lymphedema and other lymphatic anomalies are associated with 22q11.2 deletion syndrome
Marta Unolt, Jessica Barry, Maria Cristina Digilio, Bruno Marino, Anne S. Bassett, Erwin Oechslin, David W. Low, Jean B. Belasco, Staci Kallish, Kathleen E. Sullivan, ...> ;European Journal of Medical Genetics. 2018 Feb 12
Medulloblastoma With Obstructive Hydrocephalus in a Young Infant.
Ruth Abaya, Jean B. Belasco, Angela M. Ellison> ;Pediatric Emergency Care. 2017 Jun 1
377 citations
Activity of Selumetinib in Neurofibromatosis Type 1–Related Plexiform Neurofibromas
Eva Dombi, Andrea Baldwin, Leigh Marcus, Michael Fisher, Brian Weiss, AeRang Kim, Patricia Whitcomb, Staci Martin, Lindsey Aschbacher-Smith, Tilat A. Rizvi, Jianqiang ...> ;The New England Journal of Medicine. 2016 Dec 28
4 citations
Neuroplastic Response After Radiation Therapy for Pediatric Brain Tumors: A Pilot Study.
Carol L. Armstrong, Michael Fisher, Yimei Li, Robert A. Lustig, Jean B. Belasco, Jane E. Minturn, Christine E. Hill-Kayser, Sonny Batra, Peter C. Phillips> ;International Journal of Radiation Oncology, Biology, Physics. 2016 Jul 1
5 citations
Phase I study of temozolomide in combination with thiotepa and carboplatin with autologous hematopoietic cell rescue in patients with malignant brain tumors with minim...
Grace Egan, K A Cervone, P C Philips, Jean B. Belasco, Jonathan L. Finlay, Sharon Gardner> ;Bone Marrow Transplantation. 2016 Apr 1
13 citations
Premature Epiphyseal Closure of the Lower Extremities Contributing to Short Stature after cis-Retinoic Acid Therapy in Medulloblastoma: A Case Report
Jessica J. Noyes, Michael A. Levine, Jean B. Belasco, Sogol Mostoufi-Moab> ;Hormone Research in Paediatrics. 2016 Jan 1
10 citations
Carboplatin Rechallenge After Hypersensitivity Reactions in Pediatric Patients With Low-Grade Glioma
Amish C. Shah, Jane E. Minturn, Yimei Li, Jean B. Belasco, Peter C. Phillips, Tammy I. Kang, Kristina A. Cole, Angela J. Waanders, Rosanna Pollack, Concetta DiDomenico...> ;Pediatric Blood & Cancer. 2016 Jan 1
5 citations
Primary atypical optic nerve sheath meningioma in a child with restricted diffusion on magnetic resonance imaging.
S. Ali Nabavizadeh, Mariarita Santi, Jean B. Belasco, Robert A. Zimmerman> ;Journal of Neuro-Ophthalmology. 2014 Jun 1
24 citations
Nephrotic syndrome associated with tyrosine kinase inhibitors for pediatric malignancy: case series and review of the literature
Rebecca L. Ruebner, Lawrence Copelovitch, Nicholas F. Evageliou, Michelle R. Denburg, Jean B. Belasco, Bernard S. Kaplan> ;Pediatric Nephrology. 2014 May 1
72 citations
Phase 2 randomized, flexible crossover, double-blinded, placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neur...
Brigitte C. Widemann, Eva Dombi, Andrea Gillespie, Pamela L. Wolters, Jean B. Belasco, Stewart Goldman, Bruce R. Korf, Jeffrey Solomon, Staci Martin, Wanda L. Salzer, ...> ;Neuro-Oncology. 2014 May 1
2 citations
fdg-pet in two cases of neurofibromatosis type 1 and atypical malignancies
P. de Blank, Kristina A. Cole, L. Kersun, Abby M. Green, J.J. Wilkes, Jean B. Belasco, Rochelle Bagatell, L.C. Bailey, Michael Fisher> ;Current Oncology. 2014 Jan 14
5 citations
Treatment of a malignant peripheral nerve sheath tumor and its complications through a multidisciplinary approach.
Eamon J. McLaughlin, Gregory G. Heuer, Robert G. Whitmore, John K. Birknes, Jean B. Belasco, Daniel H. Sterman, David W. Low, Phillip B. Storm> ;Journal of Neurosurgery. Pediatrics. 2011 Apr 29
71 citations
Retinal nerve fiber layer thickness in children with optic pathway gliomas.
Robert A. Avery, Grant T. Liu, Michael Fisher, Graham E. Quinn, Jean B. Belasco, Peter C. Phillips, Maureen G. Maguire, Laura J. Balcer> ;American Journal of Ophthalmology. 2011 Mar 1
34 citations
A phase II study of metronomic oral topotecan for recurrent childhood brain tumors.
Jane E. Minturn, Anna J. Janss, Paul G. Fisher, Jeffrey C. Allen, Ratnakar Patti, Peter C. Phillips, Jean B. Belasco> ;Pediatric Blood & Cancer. 2011 Jan 1
56 citations
"I Want to Live, Until I don't Want to Live Anymore": Involving Children With Life-Threatening and Life-Shortening Illnesses in Decision Making About Care and Treatment
Myra Bluebond-Langner, Jean B. Belasco, Marla DeMesquita Wander> ;The Nursing Clinics of North America. 2010 Sep 1
14 citations
Surgical treatment of a clival-C2 atypical teratoid/rhabdoid tumor
Gregory G. Heuer, Heather Kiefer, Alexander R. Judkins, Jean B. Belasco, Jaclyn A. Biegel, Eric M. Jackson, Marc Cohen, Bert W. O'Malley, Phillip B. Storm> ;Journal of Neurosurgery. Pediatrics. 2010 Jan 1
19 citations
Variation in receipt of opioids by pediatric oncology patients who died in children's hospitals
Andrea D. Orsey, Jean B. Belasco, Jonas H. Ellenberg, Kathryn H. Schmitz, Chris Feudtner> ;Pediatric Blood & Cancer. 2009 Jul 1
47 citations
Phase I and Pharmacokinetic Study of the Oral Farnesyltransferase Inhibitor Lonafarnib Administered Twice Daily to Pediatric Patients With Advanced Central Nervous Sys...
Mark W. Kieran, Roger J. Packer, Arzu Onar, Susan M. Blaney, Peter C. Phillips, Ian F. Pollack, J. Russell Geyer, Sridharan Gururangan, Anu Banerjee, Stewart Goldman, ...> ;Journal of Clinical Oncology. 2007 Jul 20
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Press Mentions

19-Year-Old with Brain Tumour Managed to Stay Alive to Give Birth: ‘Death Happens in the Blink of an Eye’April 27th, 2019
Pennsylvania Teen Diagnosed with Terminal Brain Cancer Gives Birth to Healthy Baby GirlJanuary 11th, 2018
Mutation Discovery Leads to Precise Treatment for Child with Severe Lymphatic DisorderJuly 2nd, 2019