JenniferL(Miller)PicarsicMD

PubMed

• Founders of Pediatric Pathology: Dr. Ron Jaffe (1943-2022) - An Appreciation.
  Finn, L., Knisely, A., Picarsic, J.> ;Pediatric and Developmental Pathology. 2024 Feb 24
• 3 citations
  Circulating senescent myeloid cells infiltrate the brain and cause neurodegeneration in histiocytic disorders.
  Wilk, C., Cathomas, F., Török, O., Le Berichel, J., Park, M., Bigenwald, C., Heaton, G., Hamon, P., Troncoso, L., Scull, B., Dangoor, D., Silvin, A., Fleischmann, R., ...> ;Immunity. 2023 Dec 12
• Dabrafenib and trametinib in Langerhans cell histiocytosis and other histiocytic disorders.
  Eily Cournoyer, Justin Ferrell, Susan Sharp, Anish Ray, Michael Jordan, Christopher Dandoy, Michael Grimley, Somak Roy, Robert Lorsbach, Arnold C Merrow, Adam Nelson, ...> ;Haematologica. 2024 Apr 1
• Childhood-onset Erdheim-Chester disease in the molecular era: clinical phenotypes and long-term outcomes of 21 patients.
  Francesco Pegoraro, Martina Mazzariol, Irene Trambusti, Sameer Bakhshi, Saumyaranjan Mallick, Ira J Dunkel, Cor van den Bos, Özlem Tezol, Shijun Shan, Suheyla Ocak, Fl...> ;Blood. 2023 Sep 28
• 1 citations
  Lorlatinib use in an infant with thalamic ALK-positive histiocytosis.
  Irem Eldem, Jennifer Picarsic, Ashish Kumar, Yaël P Mossé, Kaleigh Filisa Roberts, Amy E Armstrong, Bryan A Sisk> ;Pediatric Blood & Cancer. 2023 Apr 19
• 1 citations
  Prior viral infection primes cross-reactive CD8+ T cells that respond to mouse heart allografts.
  M Eyad Khorki, Tiffany Shi, Eileen E Cianciolo, Ashley R Burg, P Chukwunalu Chukwuma, Jennifer L Picarsic, Mary K Morrice, E Steve Woodle, Jonathan S Maltzman, Autumn ...> ;Frontiers in Immunology. 2023 Jan 1
• 4 citations
  Histiocytic Disorders of Childhood.
  Olive S Eckstein, Jennifer Picarsic, Carl E Allen> ;Pediatrics in Review. 2022 Oct 1
• 5 citations
  Lineage switching of the cellular distribution of BRAFV600E in multisystem Langerhans cell histiocytosis.
  Paul Milne, Simon Bomken, Olga Slater, Ashish Kumar, Adam Nelson, Somak Roy, Jessica Velazquez, Kshitij Mankad, James Nicholson, Dan Yeomanson, Richard Grundy, Ahmed K...> ;Blood Advances. 2023 May 23
• 1010 citations
  The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms.
  Khoury, J., Solary, E., Abla, O., Akkari, Y., Alaggio, R., Apperley, J., Bejar, R., Berti, E., Busque, L., Chan, J., Chen, W., Chen, X., Chng, W., Choi, J., Colmenero,...> ;Leukemia. 2022 Jul 1
• 51 citations
  International expert consensus recommendations for the diagnosis and treatment of Langerhans cell histiocytosis in adults.
  Gaurav Goyal, Abdellatif Tazi, Ronald S Go, Karen L Rech, Jennifer L Picarsic, Robert Vassallo, Jason R Young, Christian W Cox, Jan Van Laar, Michelle L Hermiston, Xin...> ;Blood. 2022 Apr 28
• 50 citations
  ALK+ histiocytosis: a new clinicopathologic spectrum highlighting neurologic involvement and responses to ALK inhibition.
  Paul Geraeds Kemps, Jennifer Picarsic, Benjamin H. Durham, Zofia Hélias-Rodzewicz, Laura Sophia Hiemcke-Jiwa, Cor van den Bos, Marianne D. van de Wetering, Carel J. M....> ;Blood. 2021 Nov 2
• 1 citations
  Hypoplasia of Extrahepatic Biliary Tree and Intrahepatic Cholangiolopathy in Cystic Fibrosis Imperfectly Mimic Biliary Atresia in 4 Infants With Cystic Fibrosis and Ka...
  Kevin E. Bove, Anas Bernieh, Jennifer Picarsic, Joseph P. Cox, Edmund Yang, Philip C. Mantor, Ameet Thaker, Lauren Lazar, Meghana Sathe, Stephen M. Megison> ;The American Journal of Surgical Pathology. 2021 Nov 1
• 27 citations
  Histiocytic disorders.
  Kenneth L McClain, Camille Bigenwald, Matthew Collin, Julien Haroche, Rebecca A Marsh, Miriam Merad, Jennifer Picarsic, Karina B Ribeiro, Carl E Allen> ;Nature Reviews. Disease Primers. 2021 Oct 7
• 1 citations
  A chronic eyelid lesion in a child: multi-disciplinary approach to diagnosis, treatment and management of a highly atypical histiocytic lesion.
  Archana Ramgopal, Julia Segal, Sabrina Mukhtar, Jenny Y. Yu, Jennifer Picarsic, Jean M. Tersak, Steven William Allen> ;Pediatric Hematology and Oncology. 2021 Aug 11
• Three decades of progress from surgery to medical therapy for isolated neuroaxisV600E-positive Langerhans cell histiocytosis management: illustrative case.
  Kamil W Nowicki, Jennifer L Picarsic, Michael P D'Angelo, Daniel F Marker, Edward G Andrews, Edward A Monaco 3rd, Ajay Niranjan, Muthiah, N.> ;Journal of Neurosurgery. Case Lessons. 2021 May 10
• 16 citations
  BRAFV600E-induced senescence drives Langerhans cell histiocytosis pathophysiology.
  Camille Bigenwald, Jessica Le Berichel, C. Matthias Wilk, Rikhia Chakraborty, Steven T. Chen, Alexandra Tabachnikova, Rebecca Mancusi, Harshal Abhyankar, Maria Casanov...> ;Nature Medicine. 2021 May 1
• 8 citations
  BRAF fusions in pediatric histiocytic neoplasms define distinct therapeutic responsiveness to RAF paradox breakers.
  Payal Jain, Lea F. Surrey, Joshua Straka, Pierre Russo, Richard B. Womer, Marilyn M. Li, Phillip B. Storm, Angela J. Waanders, Michael D. Hogarty, Adam C. Resnick, Jen...> ;Pediatric Blood & Cancer. 2021 Feb 9
• 13 citations
  Discrepancies between F-18-FDG PET/CT findings and conventional imaging in Langerhans cell histiocytosis.
  Justin Ferrell, Susan Sharp, Ashok Kumar, Michael B. Jordan, Jennifer Picarsic, Adam S. Nelson> ;Pediatric Blood & Cancer. 2021 Jan 14
• 15 citations
  Bone marrow-derived myeloid progenitors as driver mutation carriers in high- and low-risk Langerhans cell histiocytosis.
  Yanling Xiao, Astrid G. S. van Halteren, Xin Lei, Jelske Borst, Eline C. Steenwijk, Tom de Wit, Joanna Grabowska, Rhianne Voogd, Paul Geraeds Kemps, Jennifer Picarsic,...> ;Blood. 2020 Nov 5
• 17 citations
  Interleukin-18 and cytotoxic impairment are independent and synergistic causes of murine virus-induced hyperinflammation
  Paul Tsoukas, Emily Rapp, Lauren Van Der Kraak, Eric S. Weiss, Vinh Dang, Corinne Schneider, Edwin Klein, Jennifer Picarsic, Rosalba Salcedo, C. Andrew Stewart, Scott ...> ;Blood. 2020 Nov 5
• 16 citations
  New molecular insights into the pathogenesis of lipoblastomas: clinicopathologic, immunohistochemical, and molecular analysis in pediatric cases
  Oscar Lopez-Nunez, Rita Alaggio, Sarangarajan Ranganathan, Lori Schmitt, Ivy John, Alanna J. Church, Jennifer Picarsic> ;Human Pathology. 2020 Oct 1
• 7 citations
  Dasatinib induces a dramatic response in a child with refractory juvenile xanthogranuloma with a novel MRC1-PDGFRB fusion.
  Shaimaa S Eissa, Michael R. Clay, Teresa Santiago, Gang Wu, Lu Wang, Barry L. Shulkin, Jennifer Picarsic, Kim E. Nichols, Patrick Campbell> ;Blood Advances. 2020 Jul 14
• 155 citations
  Erdheim-Chester disease: consensus recommendations for evaluation, diagnosis, and treatment in the molecular era
  Gaurav Goyal, Mark L. Heaney, Matthew Collin, Fleur Cohen-Aubart, Augusto Vaglio, Benjamin H. Durham, Oshrat Hershkovitz-Rokah, Michael Girschikofsky, Eric D. Jacobsen...> ;Blood. 2020 May 28
• 10 citations
  Fibrous histiocytoma/dermatofibroma in children: the same as adults?
  Lara Berklite, Sarangarajan Ranganathan, Ivy John, Jennifer Picarsic, Luisa Santoro, Rita Alaggio> ;Human Pathology. 2020 Apr 1
• 95 citations
  Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms
  Benjamin H. Durham, Estibaliz Lopez Rodrigo, Jennifer Picarsic, David H. Abramson, Veronica Rotemberg, Steven De Munck, Erwin Pannecoucke, Sydney X. Lu, Alessandro Pas...> ;Nature Medicine. 2019 Nov 25
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Journal Articles

• Langerin Staining Identifies Most Littoral Cell Angiomas but Not Most Other Splenic Angiomatous Lesions  
  Steven H Swerdlow, Jennifer Picarsic, ScienceDirect
• Prognostic significance of transcription factors [FOXA1, GATA-3] in ductal carcinoma in situ (DCIS) in terms of recurrence and Estrogen receptor (ER) status  
  Chivukula M, Picarsic J, Ahrendt, Gretchen M, Brufsky A, Carter G, Journal of Cancer Metastasis and Treatment, 1/1/2015
• Post-transplant Pediatric Burkitt lymphoma  
  Picarsic J, and Reyes-Mugica M, Pathology Case Reviews, 1/1/2011

Books/Book Chapters

• Principles of Molecular Diagnostics and Personalized Cancer Medicine 
  Chapter: Molecular Diagnostics of Pediatric Tumors. 
  Picarsic J, Nikiforova M, Reyes-MugicaEditors: Dongfeng Tan, MD and Henry Lynch, MD.Lippincott Williams & Wilkins2013

Abstracts/Posters

• Successful Implementation of Whole Slide Imaging for Pediatric Surgical Pathology: A Pilot Study.
  Jennifer Picarsic, Douglas J. Hartman, Miguel Reyes-Mugica, John Ozolek, Amy Davis MD, Ranganathan Sarangarajan, Lori Schmitt, Navid Farahani, Chelsea Watkins, Matthew..., Pathology Informatics Summit meeting, Pittsburgh, PA, 1/23/2016
• Ductal carcinoma in situ (DCIS) –Invasive carcinoma risk prediction model DRPS (DCIS Risk Prediction Score): A novel biomarker model to predict local recurrence in la...
  Bulusu,G; Brufsky, A; Picarsic,J; Ahrendt, G, Chivukula, M; Carter,G, 105th United States & Canadian Academy of Pathology’s Annual Meeting, Seattle, WA, 1/12/2016
• Langerhans cell hyperplasia, Langerhans cell histiocytosis (LCH) and the thymus: A Clinicopathologic study and review of the literature.
  Picarsic J, Egeler RM, Kudakwashe C, Patterson K, Jaffe R, 30th Histiocytosis Society Annual Meeting, Toronto, Ontario, Canada, 1/28/2014
• Can malignant thyroid nodules be distinguished from benign thyroid nodules in children and adolescents by clinical characteristics?
  Buryk M, Simons J, Joyce J, Gurtunca N, Picarsic J, Monaco S, Witchel S, Platform Session: endocrinology II: Clinical at the Pediatric Endocrine Society Annual Meeting, Vancouver, Canada, 1/5/2014
• Cytomorphologic and Radiological findings of Ectopic Thymic Tissue in Pediatric Fine Needle Aspirations.
  L Pantanowitz, J Picarsic, S Yilmaz, F Escobar, S Monaco, Journal of the American Society of Cytopatholog; 62nd America Society for Cytopathology Annual Meeting, Dallas, TX, 1/1/2014
• Role of Epstein-Barr Virus (EBV) Status and Immunophenotypic Studies in the Evaluation of Exfoliative Cytology Specimens from Patients with Post-Transplant Lymphoproli...
  Gibson S, Picarsic J, Swerdlow S, Pantanowitz L, United States & Canadian Academy of Pathology’s 103rd Annual Meeting, San Diego, CA, 1/1/2014
• Correlation of Clinicopathological Features and Molecular Genetics in Pediatric Thyroid Carcinoma.
  Picarsic J, Buryk M, Ozolek J, Ranganathan S, Monaco S, Gurtunca N, Joyce J, Simons J, Witchel S, Mehta D, and Nikiforov Y, Pediatric and Developmental Pathology; Society for Pediatric Pathology Spring Meeting, San Diego, CA, 1/1/2014
• Meeting the Needs of In-house Thyroid Cancer Patients: Identifying Appropriate Thyroglobulin and Thyroglobulin Antibody Testing Algorithms.
  Wheeler S, Picarsic J, Blair H, Peck Palmer O, Clinical Chemistry; American Association for Clinical Chemistry (AACC) annual scientific meeting, Houston, TX, 1/1/2013
• Too soon! Papillary thyroid carcinoma (PTC) in a 4 year-old child 16 months following treatment for neuroblastoma (NB)
  Buryk M, Simons S, Shaw P, Windreich R, Wine T, Joyce J, Creary S, Picarsic J, Deutsch M, Monaco S, Nikiforov Y, Witchel S, Endocrine Society Annual Meeting, San Francisco, CA, 1/1/2013
• Cerebrospinal fluid (CSF) findings in post-transplant lymphoproliferative disorder (PTLD).
  Gibson S, Monaco SE, Khalbuss WE, Picarsic J, Pantanowitz L, Journal of the Am Soc Cytopathology; American Society of Cytopathology (ASC) 60th annual scientific meeting, Las Vegas, NV, 1/1/2012
• J Picarsic, CM Salgado, L Schmitt, S Ranganathan, C Lo, M Reyes-Mugica, Modern Pathology; Society of Pediatric Pathology (SPP) Annual spring meeting, Vancouver, Canada, 1/1/2012
• Hirschsprung's disease revisited- experience with Acetylcholinesterase staining in diagnosis.
  J Picarsic, L. Schmitt, R Jaffe, Miguel Reyes-Mugica, S Ranganathan, Modern Pathology; Society of Pediatric Pathology (SPP) spring meeting, Vancouver, Canada, 1/1/2012
• Post-transplant Burkitt lymphoma: a distinct form of PTLD?
  Picarsic J, Jaffe R, Reyes MR, Pediatric Pathology Society (PPS), Padova, Italy, 1/17/2010
• Role of transcription factors [FOXA1, GATA-3] in predicting outcome in (ER+) and (ER-) ductal carcinoma-in-situ (DCIS) patients with and without invasive carcinoma (IC...
  Picarsic J, A Brufsky, G Ahernt, A Onisko, Chivukula M, United States and Canadian Academy of Pathology National Conference, 1/1/2010
• Role of transcription factors [FOXA1, GATA-3] in predicting outcomes in recurrent DCIS or invasive carcinoma in DCIS patients on core needle biopsies of breast.
  Picarsic J, A Brufsky, G Ahernt, , A Onisko, G Tseng, Chivukula M, Cancer Research; San Antonio Breast Symposium Conference, San Antonio, TX, 1/1/2009
• Adenovirus-mediated transfer of the interferon-beta gene induces tumor regression in a novel co-culture model of human lung cancer.
  PE Lamberty, JL Miller, JS Siegfried, E Favus, SM Albelda, and JM Pilewski, American Journal of Respiratory and Critical Care Medicine, 1/1/2002
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Lectures

• Activating Mutations in CSF1R and Additional Receptor Tyrosine Kinases in Sporadic and Familial Histiocytic Neoplasms 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Langerhans cell histiocytosis of the central nervous system: Challenges in pathologic diagnosis. 
  Athens, Greece - 1/28/2015
• Disorders of Histiocytosis. 
  Boston, MA - 1/22/2015
• When a granuloma is more than just a granuloma: Clues to systemic disease beyond infection. 
  1/20/2015
• Pathology and Histopathologic Pitfalls of Langerhans Cell Histiocytosis. 
  Athens, Greece - 1/15/2015
• Virtopsy: An introduction to post-mortem imaging –history, promise, and challenges. 
  Magee Women’s Hospital - 1/26/2014
• Spectrum of Coronary Artery Pathology in Pediatric Hospital Autopsy Practice. 
  Portland, OR - 1/19/2014
• Langerhans cell histiocytosis: What the CNS can tell us about Langerhans cell proliferations and new molecular updates in the field. 
  1/11/2014
• Overview of the Pediatric Autopsy. 
  1/21/2013
• Radiography in Perinatal and Pediatric Autopsies: a focus on skeletal dysplasias. 
  Magee Women’s Hospital - 1/13/2013
• The Evolution of the Pediatric Autopsy Experience: Where we've been, where we’re at, and where we're going … but who’s going to pay for it? 
  1/13/2013
• Learning Cases Pediatric Pathology: Congenital tufting enteropathy 
  Prague, Czech Republic - 1/12/2012
• From forgotten vestigial organelle to the next “hot topic” in congenital renal disease and tumorigenesis: The renaissance of the primary cilium. 
  1/27/2011
• Variability in Epstein-Barr Virus viral load assays 
  1/30/2010
• Array-based karyotyping in hematologic malignancies: Presented at the SNP arrays in CLL 
  1/19/2010
• Paroxysmal Nocturnal Hemoglobinuria: Lab testing and updates 
  UPMC - 1/20/2009
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Other

• A six-year old female transplant patient presents with fever and rectal bleeding. 
  Pejchal M and Picarsic J, UPMC Pathology Department Webcase 823
  http://path.upmc.edu/cases/case823.html
  1/1/2014
• A two-year-old male with left undescended testis. 
  Harness J and Picarsic J, UPMC Pathology Department Webcase 782
  http://path.upmc.edu/cases/case782.html
  1/1/2013
• Webcase 645: A young man with influenza. 
  Picarsic J and Contis L, UPMC Pathology Department
  http://path.upmc.edu/cases/case549.html
  1/1/2010
• Webcase 668. A 6 year-old girl with a large left neck mass. 
  Picarsic J and Reyes-Mugica M, UPMC Pathology Department
  http://path.upmc.edu/cases/case668/dx.html
  1/1/2010
• Webcase 549: An atypical myxoid leiomyoma of the vulva. 
  Picarsic J and Chivukula M, UPMC Pathology Department
  http://path.upmc.edu/cases/case549.html
  1/1/2008
• Webcase 569: A 74-year-old man with anemia. 
  Picarsic J and Gutkin D, UPMC Pathology Department
  http://path.upmc.edu/cases/case569.html
  1/1/2008
• SPP 12-11. Slide survey, Sertoli-Leydig cell hamartoma. 
  Picarsic J, Society of Pediatric Pathology Slide Survey Program
• SPP 11-15. Slide survey, hepatic adenoma. 
  Picarsic J and Ranganathan S, Society of Pediatric Pathology Slide Survey Program
• Webcase 16. Concurrent papillary carcinoma of thyroid and breast cancer metastasis to thyroid. 
  Picarsic J and Khalbuss W, UPMC Cytopathology Unknown Case Conference
  https://secure.opi.upmc.edu/cytounknowns/quiz/index.cfm
• Webcase 15. Elastofibroma. 
  Picarsic J and Khalbuss W, UPMC Cytopathology Unknown Case Conference
  https://secure.opi.upmc.edu/cytounknowns/quiz/index.cfm
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