Jessica Rose (Mckay) Castle MD

Diabetes, Lipid Metabolism

Assistant Professor, Medicine, Oregon Health and Science University School of Medicine. Preventative Cardiology

3181 SW Sam Jackson Park RdPortland, OR 97239
Phone+1 503-494-8311

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Education & Training

Oregon Health & Science University (OHSU Health)Fellowship, Endocrinology, Diabetes, and Metabolism, 2007 - 2010
Oregon Health & Science University (OHSU Health)Residency, Internal Medicine, 2004 - 2007
Oregon Health and Science University School of MedicineClass of 2004
University of Oregon’s Robert Donald Clark Honors CollegeBA, 2000

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Certifications & Licensure

OR State Medical License 2006 - 2027
WA State Medical License 2022 - 2025
MN State Medical License 2021 - 2024
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Endocrinology, Diabetes and Metabolism

Awards, Honors, & Recognition

CMS Meaningful Use Stage 2 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2012, 2014, 2016-2017
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory - Core EMR, Epic Systems Corporation, 2012, 2014, 2016-2017
Most Outstanding Curriculum Block OHSU Medical School, 2016

Clinical Trials

Efficacy and Safety of Nasal Glucagon for Treatment of Hypoglycemia in Adults
COMPLETED
PHASE3
PK/PD Study With G-Pump (Glucagon Infusion) in T1DM Patients
COMPLETED
PHASE2
Context Aware Data Gathering Study Start of enrollment: 2020 Aug 11
COMPLETED
NA

Publications & Presentations

PubMed

3 citations
Evaluation of a Prediction-Based Bedtime Intervention in Reducing Nocturnal Low Glucose in Adults With Type 1 Diabetes: The DailyDose Bedtime Smart Snack Crossover Study.
Clara Mosquera-Lopez, Valentina Roquemen-Echeverri, Peter G Jacobs, Katrina Ramsey, Joseph Pinsonault
Diabetes Care. 2025-10-01
5 citations
Factors Affecting Reproducibility of Change in Glucose During Exercise: Results From the Type 1 Diabetes and EXercise Initiative.
Zoey Li, Peter Calhoun, Michael R Rickels, Robin L Gal, Roy W Beck
Journal of Diabetes Science and Technology. 2025-07-01
12 citations
An evaluation of how exercise position statement guidelines are being used in the real world in type 1 diabetes: Findings from the type 1 diabetes exercise initiative ...
Peter G Jacobs, Martin Chase Marak, Peter Calhoun, Robin L Gal, Jessica R Castle
Diabetes Research and Clinical Practice. 2024-11-01

Journal Articles

Comparative Pharmacokinetic/Pharmacodynamic Study of Liquid Stable Glucagon vs Lyophilized Glucagon in Type 1 Diabetes Subjects
Castle JR, El Youssef J, Branigan D, Newswanger B, Strange P, Cummins M, Shi L, Prestrelski S, J Diabetes Sci Technol, 1/1/2016
Randomized Trial of a Dual-hormone Artificial Pancreas with Dosing Adjustment During Exercise Compared with No Adjustment and Sensor-augmented Pump Therapy
Jacobs P, El Youssef J, Reddy R, Resalat N, Branigan D, Condon J, Preiser N, Ramsey K, Jones M, Edwards C, Kuehl K, Leitschuh J, Rajhbeharrysing U, Castle JR, Diabetes, Obesity and Metabolism, 1/1/2016
Non-adjunctive Use of Continuous Glucose Monitoring for Diabetes Treatment Decisions
Castle JR, Jacobs PG, J Diabetes Sci Technol, 1/1/2016

Abstracts/Posters

Comparative PK/PD Study of Liquid Stable G-Pump Glucagon vs. Novo Nordisk Glucagen Delivered to T1DM Patients via an Omnipod Pump
Castle JR, Advanced Technologies and Treatments for Diabetes, 1/1/2015
The Use of Redundant Dexcom New Generation Sensors to Assess Sensor Accuracy and Performance
Castle JR, Diabetes Technology Meeting, 1/1/2012
Assessment of Hepatic Glycogen Using Magnetic Resonance Spectroscopy: Implications for Bi-hormonal Artificial Pancreas
Castle JR, American Diabetes Association 72nd Scientific Session, 1/1/2012

Lectures

Is Mini-Dose Glucagon the Answer to Preventing Exercise-Related Dysglycemia?
Portland, OR - 6/14/2014
Hypoglycemia
1/1/2017
Glucose Homeostasis
OHSU School of Medicine - 1/1/2017

Other

Monitoring and Preventing Complications
Castle JR, HealthSmart Webinar
1/1/2015

Press Mentions

Georgia and Its Hospitals Scramble to Prepare for Coronavirus SurgeApril 1st, 2020
Oregonians with Diabetes Facing Tough Choices as Insulin Prices SoarFebruary 4th, 2019
Xeris Pharmaceuticals Kicks off Dual-Hormone Artificial Pancreas TrialAugust 20th, 2018