JessicaAFlynnMD

PubMed

• 2 citations
  Transplacental Antibody Transfer of Respiratory Syncytial Virus Specific IgG in Non-Human Primate Mother-Infant Pairs.
  Michael P. Citron, Jessica McAnulty, Cheryl Callahan, Walter Knapp, Jane Fontenot, Pablo Morales, Jessica A. Flynn, Cameron M. Douglas, Amy S. Espeseth> ;Pathogens. 2021 Nov 5
• 117 citations
  SARS-CoV-2 tropism, entry, replication, and propagation: Considerations for drug discovery and development.
  Nicholas Murgolo, Alex G. Therien, Bonnie J. Howell, Daniel J. Klein, Kenneth A. Koeplinger, Linda A. Lieberman, Gregory C. Adam, Jessica A. Flynn, Philip M. McKenna, ...> ;Plos Pathogens. 2021 Feb 17
• 13 citations
  Modified mRNA/lipid nanoparticle-based vaccines expressing respiratory syncytial virus F protein variants are immunogenic and protective in rodent models of RSV infect...
  Amy S Espeseth, Pedro J Cejas, Michael P Citron, Dai Wang, Daniel J DiStefano, Cheryl Callahan, Gregory O' Donnell, Jennifer D Galli, Ryan Swoyer, Sinoeun Touch, Zhiyu...> ;NPJ Vaccines. 2020 Jan 1
• 2 citations
  Spectroscopic analysis of chlamydial major outer membrane protein in support of structure elucidation.
  Robert Hepler, Debbie D. Nahas, Bob J. Lucas, Robin M. Kaufhold, Jessica A. Flynn, Jennifer D. Galli, Ryan Swoyer, James M. Wagner, Amy S. Espeseth, Joseph G. Joyce, C...> ;Protein Science. 2018 Nov 1
• 2 citations
  Isolation of an in Vitro Affinity-Matured, Thermostable "Headless" HA Stem Fragment That Binds Broadly Neutralizing Antibodies with High Affinity
  Tariq Ahmad Najar, Uddipan Kar, Jessica A. Flynn, Raghavan Varadarajan> ;Biochemistry. 2018 Jun 4
• 11 citations
  Structure-based Design of Cyclically Permuted HIV-1 gp120 Trimers That Elicit Neutralizing Antibodies
  Sannula Kesavardhana, Raksha Das, Michael P. Citron, Rohini Datta, Linda T. Ecto, Nonavinakere Seetharam Srilatha, Daniel J. DiStefano, Ryan Swoyer, Joseph G. Joyce, S...> ;The Journal of Biological Chemistry. 2017 Jan 6
• 17 citations
  Stability Characterization of a Vaccine Antigen Based on the Respiratory Syncytial Virus Fusion Glycoprotein.
  Jessica A. Flynn, Eberhard Durr, Ryan Swoyer, Paloma Cejas, Melanie Horton, Jennifer D. Galli, Scott Cosmi, Amy S. Espeseth, Andrew J. Bett, Lan Zhang> ;Plos One. 2016 Oct 20
• 32 citations
  Hemagglutinin Sequence Conservation Guided Stem Immunogen Design from Influenza A H3 Subtype
  Vamsee Mallajosyula, Michael P. Citron, Francesca Ferrara, Nigel J. Temperton, Xiaoping Liang, Jessica A. Flynn, Raghavan Varadarajan> ;Frontiers in Immunology. 2015 Jun 26
• 141 citations
  Influenza hemagglutinin stem-fragment immunogen elicits broadly neutralizing antibodies and confers heterologous protection.
  Vamsee Mallajosyula, Michael P. Citron, Francesca Ferrara, Xianghan Lu, Cheryl Callahan, Gwendolyn J. Heidecker, Siddhartha P. Sarma, Jessica A. Flynn, Nigel J. Temper...> ;Proceedings of the National Academy of Sciences of the United States of America. 2014 Jun 24
• 32 citations
  Enhanced production of Chikungunya virus-like particles using a high-pH adapted spodoptera frugiperda insect cell line.
  James M. Wagner, J. David Pajerowski, Christopher L. Daniels, Patrick Mchugh, Jessica A. Flynn, John W. Balliet, Danilo R. Casimiro, Shyamsundar Subramanian> ;Plos One. 2014 Apr 8
• 35 citations
  Protection Provided by a Herpes Simplex Virus 2 (HSV-2) Glycoprotein C and D Subunit Antigen Vaccine against Genital HSV-2 Infection in HSV-1-Seropositive Guinea Pigs
  Sita Awasthi, John W. Balliet, Jessica A. Flynn, John M. Lubinski, Carolyn E. Shaw, Daniel J. DiStefano, Michael Cai, Martha Brown, Judith F. Smith, Rose Kowalski, Rya...> ;Journal of Virology. 2014 Feb 15
• 41 citations
  Live Attenuated Herpes Simplex Virus 2 Glycoprotein E Deletion Mutant as a Vaccine Candidate Defective in Neuronal Spread
  Sita Awasthi, Elizabeth E. Zumbrun, Huaxin Si, Fushan Wang, Carolyn E. Shaw, Michael Cai, John M. Lubinski, Shana M. Barrett, John W. Balliet, Jessica A. Flynn, Danilo...> ;Journal of Virology. 2012 Apr 15
• 20 citations
  Design and synthesis of conformationally constrained inhibitors of non-nucleoside reverse transcriptase.
  Robert P. Gomez, Samson J. Jolly, Theresa M. Williams, Joseph P. Vacca, Maricel Torrent, Georgia B. McGaughey, Ming-Tain Lai, Peter J. Felock, Vandna Munshi, Daniel J....> ;Journal of Medicinal Chemistry. 2011 Oct 28
• 55 citations
  Immunization with a vaccine combining herpes simplex virus 2 (HSV-2) glycoprotein C (gC) and gD subunits improves the protection of dorsal root ganglia in mice and red...
  Sita Awasthi, John M. Lubinski, Carolyn E. Shaw, Shana M. Barrett, Michael Cai, Fushan Wang, Michael R. Betts, Susan Kingsley, Daniel J. DiStefano, John W. Balliet, Je...> ;Journal of Virology. 2011 Oct 15
• 47 citations
  Potent and selective HIV-1 ribonuclease H inhibitors based on a 1-hydroxy-1,8-naphthyridin-2(1H)-one scaffold.
  Peter D. Williams, Donnette D. Staas, Shankar Venkatraman, H. Marie Loughran, Rowena D. Ruzek, Theresa M. Booth, Terry A. Lyle, John S. Wai, Joseph P. Vacca, Bradley P...> ;Bioorganic & Medicinal Chemistry Letters. 2010 Nov 15
• 9 citations
  Biaryl ethers as potent allosteric inhibitors of reverse transcriptase and its key mutant viruses: Aryl substituted pyrazole as a surrogate for the pyrazolopyridine motif
  Dai-Shi Su, John Jin Lim, Elizabeth Tinney, Thomas J. Tucker, Saggar Sandeep A, John T. Sisko, Bang-Lin Wan, Mary Beth Young, Kenneth D. Anderson, Deanne Rudd, Vandna ...> ;Bioorganic & Medicinal Chemistry Letters. 2010 Aug 1
• 28 citations
  Efficacy of Multivalent Adenovirus-Based Vaccine against Simian Immunodeficiency Virus Challenge
  Danilo R. Casimiro, Kara S. Cox, Aimin Tang, Kara J. Sykes, Meizhen Feng, Fubao Wang, Andrew J. Bett, William A. Schleif, Xiaoping Liang, Jessica A. Flynn, Timothy W. ...> ;Journal of Virology. 2010 Mar 15
• 19 citations
  Biaryl Ethers as Novel Non-nucleoside Reverse Transcriptase Inhibitors with Improved Potency against Key Mutant Viruses
  Dai-Shi Su, John Jin Lim, Elizabeth Tinney, Bang-Lin Wan, Mary Beth Young, Kenneth D. Anderson, Deanne Rudd, Vandna Munshi, Carolyn Bahnck, Peter J. Felock, Meiquing L...> ;Journal of Medicinal Chemistry. 2009 Nov 2
• 21 citations
  Substituted tetrahydroquinolines as potent allosteric inhibitors of reverse transcriptase and its key mutants
  Dai-Shi Su, John Jin Lim, Elizabeth Tinney, Bang-Lin Wan, Mary Beth Young, Kenneth D. Anderson, Deanne Rudd, Vandna Munshi, Carolyn Bahnck, Peter J. Felock, Meiqing Lu...> ;Bioorganic & Medicinal Chemistry Letters. 2009 Sep 1
• 58 citations
  Discovery of 3-{5-[(6-amino-1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5-chlorobenzonitrile (MK-4965): a potent, orally bioavailable HIV-1 non-nucleosid...
  Thomas J. Tucker, John T. Sisko, Tynebor Robert M, Theresa M. Williams, Peter J. Felock, Jessica A. Flynn, Ming-Tain Lai, Yuexia Liang, Georgia B. McGaughey, Meiquing ...> ;Journal of Medicinal Chemistry. 2008 Oct 1
• 40 citations
  The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mut...
  Thomas J. Tucker, Saggar Sandeep A, John T. Sisko, Robert M. Tynebor, Theresa M. Williams, Peter J. Felock, Jessica A. Flynn, Ming-Tain Lai, Yuexia Liang, Georgia B. M...> ;Bioorganic & Medicinal Chemistry Letters. 2008 May 1
• 28 citations
  Two distinct Moloney murine leukemia virus RNAs produced from a single locus dimerize at random.
  Jessica A. Flynn, Alice Telesnitsky> ;Virology. 2006 Jan 20
• 39 citations
  Nonrandom Dimerization of Murine Leukemia Virus Genomic RNAs
  Jessica A. Flynn, Wenfeng An, Steven R. King, Alice Telesnitsky> ;Journal of Virology. 2004 Nov 15
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