JodieLynnBabittMD

PubMed

• Bone morphogenic proteins in iron homeostasis.
  Xiao, X., Alfaro-Magallanes, V. M., Babitt, J. L.> ;Bone. 2020 Jun 26
• Erythroferrone lowers hepcidin by sequestering BMP2/6 heterodimer from binding to the BMP type I receptor ALK3.
  Wang, C., Xu, Y., Traeger, L., Dogan, D. Y., Xiao, X., Steinbicker, A. U., Babitt, J. L.> ;Blood. 2019 Dec 5
• Endothelial Bone Morphogenetic Protein 2 (Bmp2) Knockout Exacerbates Hemochromatosis in Homeostatic Iron Regulator (Hfe) Knockout Mice but not Bmp6 Knockout Mice.
  Xiao, X., Dev, S., Canali, S., Bayer, A., Xu, Y., Agarwal, A., Wang, C., Babitt, J. L.> ;Hepatology (Baltimore, Md.). 2019 Nov 30
• Nrf2 controls iron homeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin.
  Lim, P. J., Duarte, T. L., Arezes, J., Garcia-Santos, D., Hamdi, A., Pasricha, S., Armitage, A. E., Mehta, H., Wideman, S., Santos, A. G., Santos-Gonçalves, A., Morova...> ;Nature metabolism. 2019 Jul 6
• Ironing out pulmonary arterial hypertension.
  Babitt, J. L.> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Jun 7
• Crosstalk between fibroblast growth factor 23, iron, erythropoietin, and inflammation in kidney disease.
  Babitt, J. L., Sitara, D.> ;Current opinion in nephrology and hypertension. 2019 May 31
• Ablation of Hepatocyte Smad1, Smad5, and Smad8 Causes Severe Tissue Iron Loading and Liver Fibrosis in Mice.
  Wang, C., Xiao, X., Bayer, A., Xu, Y., Dev, S., Canali, S., Nair, A. V., Masia, R., Babitt, J. L.> ;Hepatology (Baltimore, Md.). 2019 May 28
• Iron, Hepcidin, and Death in Human AKI.
  Leaf, D. E., Rajapurkar, M., Lele, S. S., Mukhopadhyay, B., Boerger, E. A., Causland, F. R., Eisenga, M. F., Singh, K., Babitt, J. L., Kellum, J. A., Palevsky, P. M., ...> ;Journal of the American Society of Nephrology : JASN. 2019 Feb 10
• Antiviral activity of bone morphogenetic proteins and activins.
  Eddowes, L. A., Al-Hourani, K., Ramamurthy, N., Frankish, J., Baddock, H. T., Sandor, C., Ryan, J. D., Fusco, D. N., Arezes, J., Giannoulatou, E., Boninsegna, S., Chev...> ;Nature microbiology. 2018 Dec 5
• Iron, erythropoietin, and inflammation regulate hepcidin in Bmp2-deficient mice, but serum iron fails to induce hepcidin in Bmp6-deficient mice.
  Wang, C., Canali, S., Bayer, A., Dev, S., Agarwal, A., Babitt, J. L.> ;American journal of hematology. 2018 Nov 28
• Liver iron sensing and body iron homeostasis.
  Wang, C., Babitt, J. L.> ;Blood. 2018 Nov 8
• 1 citation
  Large G protein α-subunit XLαs limits clathrin-mediated endocytosis and regulates tissue iron levels in vivo.
  He, Q., Bouley, R., Liu, Z., Wein, M. N., Zhu, Y., Spatz, J. M., Wang, C., Pajevic, P. D., Plagge, A., Babitt, J. L., Bastepe, M.> ;Proceedings of the National Academy of Sciences of the United States of America. 2017 Oct 29
• 5 citations
  Overview of iron metabolism in health and disease.
  Dev, S., Babitt, J. L.> ;Hemodialysis international. International Symposium on Home Hemodialysis. 2017 Mar 16
• 7 citations
  Ironing out the cross talk between FGF23 and inflammation.
  David, V., Francis, C., Babitt, J. L.> ;American journal of physiology. Renal physiology. 2016 Sep 2
• The SMAD Pathway Is Required for Hepcidin Response During Endoplasmic Reticulum Stress
  Jodie Babitt, MD> ;Endocrinology.
• On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver.
  Theurl, I., Hilgendorf, I., Nairz, M., Tymoszuk, P., Haschka, D., Asshoff, M., He, S., Gerhardt, L. M., Holderried, T. A., Seifert, M., Sopper, S., Fenn, A. M., Anzai,...> ;Nature medicine. 2016 Jul 19
• 11 citations
  Hepcidin regulation in the anemia of inflammation.
  Wang, C., Babitt, J. L.> ;Current opinion in hematology. 2016 Feb 18
• 17 citations
  Activin B Induces Noncanonical SMAD1/5/8 Signaling via BMP Type I Receptors in Hepatocytes: Evidence for a Role in Hepcidin Induction by Inflammation in Male Mice.
  Canali, S., Core, A. B., Zumbrennen-Bullough, K. B., Merkulova, M., Wang, C., Schneyer, A. L., Pietrangelo, A., Babitt, J. L.> ;Endocrinology. 2016 Jan 7
• 46 citations
  Inflammation and functional iron deficiency regulate fibroblast growth factor 23 production.
  David, V., Martin, A., Isakova, T., Spaulding, C., Qi, L., Ramirez, V., Zumbrennen-Bullough, K. B., Sun, C. C., Lin, H. Y., Babitt, J. L., Wolf, M.> ;Kidney international. 2015 Nov 5
• 3 citations
  Hepcidin regulation in prostate and its disruption in prostate cancer.
  Tesfay, L., Clausen, K. A., Kim, J. W., Hegde, P., Wang, X., Miller, L. D., Deng, Z., Blanchette, N. L., Arvedson, T., Miranti, C. K., Babitt, J. L., Lin, H. Y., Peehl...> ;Cancer research. 2015 Apr 11
• BuMPing iron with modified heparins.
  Babitt, J. L., Lin, H. Y.> ;Blood. 2014 Mar 15
• 5 citations
  The liver: conductor of systemic iron balance.
  Meynard, D., Babitt, J. L., Lin, H. Y.> ;Blood. 2013 Nov 10
• 4 citations
  Heterologous downregulation of vasopressin type 2 receptor is induced by transferrin.
  Bouley, R., Nunes, P., Andriopoulos, B., McLaughlin, M., Webber, M. J., Lin, H. Y., Babitt, J. L., Gardella, T. J., Ausiello, D. A., Brown, D.> ;American journal of physiology. Renal physiology. 2012 Dec 14
• 6 citations
  Statement of concern about a commercial assay used to measure soluble hemojuvelin in humans.
  Gutiérrez, O. M., Sun, C. C., Chen, W., Babitt, J. L., Lin, H. Y.> ;American journal of nephrology. 2012 Sep 26
• 3 citations
  A novel validated enzyme-linked immunosorbent assay to quantify soluble hemojuvelin in mouse serum.
  Chen, W., Sun, C. C., Chen, S., Meynard, D., Babitt, J. L., Lin, H. Y.> ;Haematologica. 2012 Aug 10
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Lectures

• When Bone Mineral Disease and Anemia Management Collide 
  American Society of Nephrology Kidney Week 2019 - Washington, D.C. - 11/8/2019
• Liver Iron Sensing and Body Iron Homeostasis 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019