
John Mark Flack MD MPH (He/Him)
Chair, Departments of Medicine and Population Science and Policy Southern Illinois University
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751 N Rutledge StSte 1100Springfield, IL 62702
Phone+1 217-545-8000
Fax+1 217-545-4735
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Summary
- John M. Flack, MD, MPH is an Internal Medicine and Hypertension specialist/cardiovascular epidemiologist based in Springfield, IL. He completed his education at the University of Oklahoma College of Medicine and his residency in Internal Medicine at the University of Oklahoma Health Sciences Center where he was elected to the Alpha Omega Alpha Honor Society. Dr. Flack also served as Chief Medicine Resident at the University of Oklahoma. Dr. Flack has over 250 peer-reviewed publications in the field of hypertension, hypertension therapeutics, hypertension in African Americans, resistant/refractory hypertension and device-based hypertension treatments. His research focuses on these same areas. He is an Associate Editor at the journal Hypertension, the premier hypertension journal in the world. Dr. Flack also authored the chapter on Arterial Hypertension in the current edition of Goldman-Cecils textbook of Medicine. Dr. Flack has been recognized with honors such as Regional Top Doctor, Best Doctor, Super Doctor, Crain's Health Care Hero and Michiganian of the Year. He is the Sergio Rabinovich Endowed Chair of Internal Medicine and the Chair of the Departments of Medicine and Population Science and Policy at Southern Illinois University. Dr. Flack also serves as President of the American Hypertension Specialist Certification Program.
Education & Training
University of Oklahoma Health Sciences CenterResidency, Internal Medicine, 1982 - 1986
University of Oklahoma College of MedicineClass of 1982
Certifications & Licensure
IL State Medical License 2015 - 2026
MI State Medical License 1997 - 2016
NC State Medical License 1994 - 1998
MN State Medical License 1988 - 1995
OK State Medical License 1983 - 1989
American Board of Internal Medicine Internal Medicine
Awards, Honors, & Recognition
- Regional Top Doctor Castle Connolly, 2014
- Super Doctor SuperDoctors.com
Clinical Trials
- SDCC - Prospective Cohort Study of Chronic Renal Insufficiency
- Bioimpedance Evaluation of Therapeutic Titration in Essential, Refractory Hypertension Start of enrollment: 2009 Jan 01
- Aspirin in Reducing Events in the Elderly Start of enrollment: 2010 Jan 01
Publications & Presentations
PubMed
- Aprocitentan in Patients With Chronic Kidney Disease and Resistant Hypertension.Patrick Rossignol, Martine Clozel, Roland F Dreier, John M Flack, Bruno Flamion
Hypertension. 2026-02-01 - Carbon Dioxide Angiography-Guided Ultrasound Renal Denervation in Refractory Hypertension With Chronic Kidney Disease.Mohamad Bahrou, Ahmed Shahab, Rami Al-Ayyubi, John Flack, Abdul Moiz Hafiz
JACC. Case Reports. 2026-01-07 - Effects of aprocitentan on prognostically relevant ambulatory blood pressure-derived variables in resistant hypertension.Markus P Schlaich, Michael A Weber, John M Flack, Parisa Danaietash, Mouna Sassi-Sayadi
Journal of Hypertension. 2026-01-01
Press Mentions
SIU Medicine Expands Kidney Care ServicesApril 4th, 2025
AHA Scientific Statement on Renal Denervation to Treat Hypertension PublishedAugust 9th, 2024
Are Heart Rate and Blood Pressure the Same? No, and It's Important to Understand WhyMay 16th, 2023
Grant Support
- Obesity, Nitric Oxide, Oxidative Stress, And SALT SensitivityNational Institute Of Environmental Health Sciences2007
- Administrative CoreNational Institute Of Environmental Health Sciences2007
- Center For African American Urban HealthNational Institute Of Environmental Health Sciences2003–2007
- Blood Pressure Lowering Mechanisms Of Angiotensin Converting EnzymeNational Center For Research Resources1996–1997
- Study Coronary Heart Disease Risk In Young AdultsDivision Of Epidemiology And Clinical Applications1991–1994
Research History
- Post-doctdoral Research FellowNIH post-doctoral fellow in cardiovascular epidemiology at the University of Minnesota School of Public Health, Division of Epidemiology; Richard Grimm, MD, PHD (Primary Mentor)1988 - 1990
Professional Memberships
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