JohnAlanGrayMDPhD

PubMed

• 83 citations
  Activated CaMKII couples GluN2B and Casein Kinase 2 to control synaptic NMDA Receptors
  Antonio Sanz-Clemente, John A. Gray, Kyle A. Ogilvie, Roger A. Nicoll, Katherine W. Roche> ;Cell Reports. 2013 Mar 28
• D-serine availability modulates prefrontal cortex inhibitory interneuron development and circuit maturation.
  Oluwarotimi O Folorunso, Stephanie E Brown, Jugajyoti Baruah, Theresa L Harvey, Shekib A Jami, Inna Radzishevsky, Herman Wolosker, James M McNally, John A Gray, Anju V...> ;Scientific Reports. 2023 Jun 13
• 1 citations
  GluN3A subunit tunes NMDA receptor synaptic trafficking and content during postnatal brain development.
  Inmaculada M González-González, John A Gray, Joana Ferreira, María Jose Conde-Dusman, Delphine Bouchet, Isabel Perez-Otaño, Laurent Groc> ;Cell Reports. 2023 May 30
• 71 citations
  Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors.
  Maxemiliano V Vargas, Lee E Dunlap, Chunyang Dong, Samuel J Carter, Robert J Tombari, Shekib A Jami, Lindsay P Cameron, Seona D Patel, Joseph J Hennessey, Hannah N Sae...> ;Science. 2023 Feb 17
• 17 citations
  5-HT2ARs Mediate Therapeutic Behavioral Effects of Psychedelic Tryptamines.
  Lindsay P Cameron, Seona D Patel, Maxemiliano V Vargas, Eden V Barragan, Hannah N Saeger, Hunter T Warren, Winston L Chow, John A Gray, David E Olson> ;ACS Chemical Neuroscience. 2023 Feb 1
• 4 citations
  SOX2 is essential for astrocyte maturation and its deletion leads to hyperactive behavior in mice.
  Yan Wang, Sheng Zhang, Zhaohui Lan, Vui Doan, Bokyung Kim, Sihan Liu, Meina Zhu, Vanessa L Hull, Sami Rihani, Chun-Li Zhang, John A Gray, Fuzheng Guo> ;Cell Reports. 2022 Dec 20
• 7 citations
  Reduced d-serine levels drive enhanced non-ionotropic NMDA receptor signaling and destabilization of dendritic spines in a mouse model for studying schizophrenia.
  Deborah K Park, Samuel Petshow, Margarita Anisimova, Eden V Barragan, John A Gray, Ivar S Stein, Karen Zito> ;Neurobiology of Disease. 2022 Aug 1
• 8 citations
  Thinking Outside the Synapse: Glycine at Extrasynaptic NMDA Receptors
  John A. Gray, Roger A. Nicoll> ;Cell. 2012 Aug 3
• 12 citations
  Excessive Laughter-like Vocalizations, Microcephaly, and Translational Outcomes in the Ube3a Deletion Rat Model of Angelman Syndrome.
  Elizabeth L. Berg, Shekib A. Jami, Stela P. Petkova, Annuska Berz, Timothy A. Fenton, Jason P. Lerch, David J. Segal, John A. Gray, Jacob Ellegood, Markus Wöhr, Jill L...> ;The Journal of Neuroscience. 2021 Sep 2
• 12 citations
  Increased excitation-inhibition balance and loss of GABAergic synapses in the serine racemase knockout model of NMDA receptor hypofunction
  Shekib A. Jami, Scott Cameron, Jonathan M. Wong, Emily R. Daly, A. Kimberly McAllister, John A. Gray> ;Journal of Neurophysiology. 2021 Jul 1
• 60 citations
  SAP102 Mediates Synaptic Clearance of NMDA Receptors
  Bo Shiun Chen, John A. Gray, Antonio Sanz-Clemente, Zhe Wei, Eleanor V. Thomas, Roger A. Nicoll, Katherine W. Roche> ;Cell Reports. 2012 Nov 29
• 24 citations
  Postsynaptic Serine Racemase Regulates NMDA Receptor Function.
  Jonathan M. Wong, Oluwarotimi Folorunso, Eden V. Barragan, Cristina Berciu, Theresa L. Harvey, Joseph T. Coyle, Darrick T. Balu, John A. Gray> ;The Journal of Neuroscience. 2020 Dec 9
• 12 citations
  The Role of Glutamate in Language and Language Disorders - Evidence from ERP and Pharmacologic Studies.
  Wentao Li, Marta Kutas, John A. Gray, Randi H. Hagerman, John M Olichney> ;Neuroscience and Biobehavioral Reviews. 2020 Dec 1
• 17 citations
  NMDAR-Activated PP1 Dephosphorylates GluN2B to Modulate NMDAR Synaptic Content
  Andrew M. Chiu, Jiejie Wang, Michael P. Fiske, Pavla Hubalkova, Levi Barse, John A. Gray, Antonio Sanz-Clemente> ;Cell Reports. 2019 Jul 9
• 212 citations
  Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivo.
  John A. Gray, Yun Shi, Hiroshi Usui, Matthew J. During, Kenji Sakimura, Roger A. Nicoll> ;Neuron. 2011 Sep 22
• 19 citations
  Metaplasticity contributes to memory formation in the hippocampus
  Ana Paula Crestani, Jamie N. Krueger, Eden V. Barragan, Yuki Nakazawa, Sonya E. Nemes, Jorge Alberto Quillfeldt, John A. Gray, Brian J. Wiltgen> ;Neuropsychopharmacology. 2019 Jan 1
• 25 citations
  Excitotoxic superoxide production and neuronal death require both ionotropic and non-ionotropic NMDA receptor signaling.
  Angela M. Minnella, Jerry X. Zhao, Xiangning Jiang, Emil Jakobsen, Fuxin Lu, Long Wu, Jamel El-Benna, John A. Gray, Raymond A. Swanson> ;Scientific Reports. 2018 Nov 30
• 29 citations
  Genetic analysis of neuronal ionotropic glutamate receptor subunits.
  Adam J. Granger, John A. Gray, Wei Lu, Roger A. Nicoll> ;The Journal of Physiology. 2011 Sep 1
• 5 citations
  Incomplete block of NMDA receptors by intracellular MK-801.
  Weinan Sun, Jonathan M. Wong, John A. Gray, Brett C. Carter> ;Neuropharmacology. 2018 Dec 1
• 15 citations
  Potentiation of Synaptic AMPA Receptors Induced by the Deletion of NMDA Receptors Requires the GluA2 Subunit
  Wei Lu, John A. Gray, Adam J. Granger, Matthew J. During, Roger A. Nicoll> ;Journal of Neurophysiology. 2011 Feb 1
• 445 citations
  Psychedelics Promote Structural and Functional Neural Plasticity
  Calvin Ly, Alexandra C. Greb, Lindsay P. Cameron, Jonathan M. Wong, Eden V. Barragan, Paige C. Wilson, Kyle F. Burbach, Sina Soltanzadeh Zarandi, Alexander Sood, Micha...> ;Cell Reports. 2018 Jun 12
• 18 citations
  Long-Term Depression Is Independent of GluN2 Subunit Composition.
  Jonathan M. Wong, John A. Gray> ;The Journal of Neuroscience. 2018 Mar 28
• Corrigendum: Sestd1 encodes a developmentally dynamic synapse protein that complexes with BCR Rac1-GAP to regulate forebrain dendrite, spine and synapse formation (Cer...
  Xiao Yong Yang, Robert E. Stanley, Adam P. Ross, Aaron M. Robitaille, John A. Gray, Benjamin N.R. Cheyette> ;Cerebral Cortex. 2019 Mar 1
• 278 citations
  Metabolic control of vesicular glutamate transport and release.
  Narinobu Juge, John A. Gray, Hiroshi Omote, Takaaki Miyaji, Tsuyoshi Inoue, Chiaki Hara, Hisayuki Uneyama, Robert H. Edwards, Roger A. Nicoll, Yoshinori Moriyama> ;Neuron. 2010 Oct 6
• 1 citations
  Sestd1 Encodes a Developmentally Dynamic Synapse Protein That Complexes With BCR Rac1-GAP to Regulate Forebrain Dendrite, Spine and Synapse Formation.
  Xiao Yong Yang, Robert E Stanley, Adam P Ross, Aaron M Robitaille, John A Gray, Benjamin N R Cheyette> ;Cerebral Cortex. 2019 Feb 1
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Journal Articles

• When clozapine is not enough. Augment with lamotrigine?  
  Gray JA, Risch SC, Current Psychiatry
• Developing selectively non-selective drugs for treating CNS disorders.  
  Gray JA, Roth BL, Drug Discovery Today: Therapeutic Strategies

Books/Book Chapters

• Kaplan & Sadock’s Comprehensive Textbook of Psychiatry 
  Chapter: Intraneuronal Signaling 
  Page 118 - 129Gray JA, Roth BLEditors: Sadock BJ, Sadock VA, Ruiz P.Lippincott Williams & Wilkins, Philadelphia
• Handbook of Contemporary Neuropharmacology 
  Chapter: Serotonin Systems 
  Page 257 - 298Gray JA, Roth BLEditors: Sibley DR, Hanin I, Kuhar M, Skolnick P.John Wiley & Sons, New York
• Basic and Clinical Pharmacology 
  Chapter: Introduction to the Pharmacology of CNS Drugs 
  Page 355 - 368Gray JA, Nicoll RAEditors: Katzung BG.McGraw-Hill, New York, NY2014
• Ferri’s Clinical Advisor 2013 
  Chapter: Tardive Dyskinesia 
  Gray JAEditors: Ferri FF.Mosbi, PhiladelphiaEdition 2013,
• Ferri’s Clinical Advisor 2012 
  Chapter: Tardive Dyskinesia 
  Gray JAEditors: Ferri FF.Mosbi, PhiladelphiaEdition 2012,
• Ferri’s Clinical Advisor 2011 
  Chapter: Tardive Dyskinesia 
  Page 1069 - 1070Gray JAEditors: Ferri FF.Mosbi, PhiladelphiaEdition 2011,
• Ferri’s Clinical Advisor 2010 
  Chapter: Tardive Dyskinesia 
  Gray JA, Lai AEditors: Ferri FF.Mosbi, PhiladelphiaEdition 2010,
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Abstracts/Posters

• Novel molecular replacement strategy for dissecting synaptic and extrasynaptic NMDA receptor targeting.
  Gray JA, Sanz-Clemente A, Roche KW, Nicoll RA, Federation of European Neuroscience Societies Annual Meeting, Barcelona, Spain
• CaMKII binding to GluN2B controls synaptic NMDAR composition by facilitating the phosphorylation of the GluN2B PDZ ligand
  Sanz-Clemente A, Gray JA, Ogilvie KA, Nicoll RA, Roche KW, for Neuroscience, New Orleans, LA
• Distinct modes of AMPA receptor suppression at developing synapses by the NMDA receptor subunits GluN2A and GluN2B.
  Gray JA, Usui H, During MJ, Sakimura K, Nicoll RA, Society for Neuroscience, Washington DC
• Designing a neuroscience curriculum based upon constructivist learning principles.
  Rose DA, Gray JA, Association for Academic Psychiatry, Santa Fe, NM
• A constitutively active arrestin rescues arrestin-insensitivity of the 5-HT2A receptor and induces agonist-independent internalization.
  Gray JA, Bhatnagar A, Gurevich VV, Roth BL, Great Lakes GPCR Retreat, Ann Arbor, MI
• Cell-type specific role of endocytosis in 5-HT2A receptor desensitization and resensitization: Arrestin-independent regulation in HEK-293 cells is unrelated to the le...
  Gray JA, Sheffler DJ, Kroeze WK, Roth BL, Society for Neuroscience, San Diego, CA
• Novel techniques for probing receptor-G-protein interactions: G-protein affinity chromatography and i3-ELISA.
  Hyde EG, Gray JA, Gelber EI, Kroeze WK, Roth BL, Society for Neuroscience, San Diego, CA
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