JohnShu ShinKuoMDPhD FAANS FACS(He/Him)

Brain & Spinal Tumor, Pituitary Surgery, Stereotactic & Functional Neurosurgery

Vice President, China Medical University (Taiwan), Chair Professor, China Medical University (Taiwan); Yu Shan Scholar (Taiwan); Professor, Dept. of Neurosurgery, University of Texas at Austin

Join to view full profile

Dr. Kuo is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Connect with other colleagues in the same hospital or clinic
Search all U.S. specialist profiles and refer a patient
Read the latest clinical news and earn CME/CEU credits

See Dr. Kuo's full profile

Already have an account?

Office
1601B Trinity St Stop Z1500
Austin, TX 78712
Phone+1 512-495-5557

Fax+1 512-495-5610
Is this information wrong?

Summary

Dr. John Kuo is a board-certified neurosurgeon-scientist who serves as Vice President of Medical Affairs and Chair Professor at China Medical University in Taichung, Taiwan. He is a senior leader at this top private university composed of 10 colleges and schools, over 7000 students and trainees, and an integrated academic health system of major hospitals and clinics with over 6000 beds across Taiwan.

He also is a Professor and served as the past-Inaugural Chair of the Dept. of Neurosurgery at Dell Medical School of The University of Texas at Austin. He received his MD from Harvard Medical School, PhD degree from MIT. He specializes in surgery for brain tumors, pituitary tumors, stereotactic radiosurgery for brain tumors, brain metastases and trigeminal neuralgia, and clinical management of complex brain tumor conditions. Dr. Kuo leads a research group that studies cancer stem cell biology, developing new cancer diagnostics and therapeutics, and leading clinical trials of new cancer agents. at UT Austin, he started a department of neurosurgeons and scientists dedicated to advancing the clinical care, full spectrum research and educational frontiers for children and adults with brain and spine diseases via new surgical techniques and devices, novel biological and immunotherapies, biomedical sciences and engineering new technologies in multidisciplinary teams focused on advancing brain-computer interface, neurorehabilitation, brain and spine trauma, cerebrovascular/stroke and brain tumor translational research groups. He was also Surgical director and helped lead the UT Mulva Clinic for the Neurosciences, an interdisciplinary enterprise of Neurosurgery, Neurology, Psychiatry, and Basic Neurosciences focused on improving outcomes for patients with neurological disorders.

Education & Training

University of Southern California/LAC+USC Medical CenterResidency, Neurological Surgery, 1998 - 2005
University of Southern California/LACUSC Medical CenterFellowship, Stereotactic Radiosurgery, 2002 - 2003
Harvard Medical SchoolClass of 1998

Certifications & Licensure

CA State Medical License 1999 - 2025
TX State Medical License 2018 - 2024
WI State Medical License 2005 - 2019
American Board of Neurological Surgery Neurological Surgery

Awards, Honors, & Recognition

Top Doctors Austin Monthly, 2020-2022
America's Top Doctors Castle Connolly, 2012-2022
Fellow (FAANS) American Association of Neurological Surgeons
American Academy of Neurological Surgeons (elected) American Academy of Neurological Surgeons, 2017
Preuss Brain Tumor Award AANS/CNS Joint Tumor Section, 2015
Society of University Surgeons (elected) Society of University Surgeons, 2015
America's Top Surgeons Consumers Research Council of America, 2011-2013
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011
Fellow (FACS) American College of Surgeons
Join now to see all

Clinical Trials

Imaging Trial With I-124-CLR1404 in Patients With Newly Diagnosed or Recurrent Glioblastoma Start of enrollment: 2014 Feb 01
Terminated
Phase 2

Publications & Presentations

PubMed

Developing an AI-assisted planning pipeline for hippocampal avoidance whole brain radiotherapy.
Chih-Yuan Lin, Lin-Shan Chou, Yuan-Hung Wu, John S Kuo, Minesh P Mehta, An-Cheng Shiau, Ji-An Liang, Shih-Ming Hsu, Ti-Hao Wang> ;Radiotherapy and Oncology. 2023 Apr 1
Emerging Frontiers of Therapeutic Strategies for Brain Tumors: A NeuroMolecular Medicine Special Issue.
Vishwanath R Iyer, John S Kuo> ;Neuromolecular Medicine. 2022 Mar 1
1 citations
Characterizing the relationship between lesion-activation distance using fMRI and verbal measures in brain tumor patients
Sean P. Riley, Daniel Y. Chu, Veena A. Nair, Mustafa K. Baskaya, John S. Kuo, Mary E. Meyerand, Vivek Prabhakaran> ;Interdisciplinary Neurosurgery. 2022 Mar 1
10 citations
Enhanced expression of pentraxin-3 in glioblastoma cells correlates with increased invasion and IL8-VEGF signaling axis.
Umadevi V Wesley, Ian Sutton, Paul A Clark, Katelin Cunningham, Carolina Larrain, John S Kuo, Robert J Dempsey> ;Brain Research. 2022 Feb 1
Identification of Brain ECM Binding Variable Lymphocyte Receptors Using Yeast Surface Display.
Benjamin J Umlauf, John S Kuo, Eric V Shusta> ;Methods in Molecular Biology. 2022 Jan 1
5 citations
Emerging Epigenetic Therapies for Brain Tumors
Lokesh Kukreja, Catherine J Li, Sathyapriya Ezhilan, Vishwanath R. Iyer, John S. Kuo> ;Neuromolecular Medicine. 2021 Oct 22
MicroRNA miR-100 Decreases Glioblastoma Growth by Targeting SMARCA5 and ErbB3 in Tumor-Initiating Cells.
Alrfaei BM, Clark P, Vemuganti R, Kuo JS> ;Technology in cancer research & treatment.
In situ vaccination at a peripheral tumor site augments response against melanoma brain metastases.
Clark PA, Sriramaneni RN, Jin WJ, Jagodinsky JC, Bates AM, Jaquish AA, Anderson BR, Le T, Lubin JA, Chakravarty I, Arthur IS, Heinze CM, Guy EI, Kler J, Klar KA, Carls...> ;Journal for immunotherapy of cancer.
Neuronavigation-guided focused ultrasound (NaviFUS) for transcranial blood-brain barrier opening in recurrent glioblastoma patients: clinical trial protocol.
Chen KT, Lin YJ, Chai WY, Lin CJ, Chen PY, Huang CY, Kuo JS, Liu HL, Wei KC> ;Annals of translational medicine.
Neoantigen-Targeting Vaccine Promotes T-Cell Response in Glioblastoma.
Traylor JI, Satarasinghe P, Kuo JS> ;Neurosurgery.
[124I]CLR1404 PET/CT in High-Grade Primary and Metastatic Brain Tumors.
Hall LT, Titz B, Baidya N, van der Kolk AG, Robins HI, Otto M, Perlman SB, Weichert JP, Kuo JS> ;Molecular imaging and biology.
Combined Nivolumab and Ipilimumab Is an Effective Treatment for Melanoma Brain Metastases.
Traylor JI, Kuo JS> ;Neurosurgery.
Delta-24-RGD Adenoviral Therapy Directs Oncolytic and Immune-Mediated Anti-Tumor Effects in Recurrent Malignant Glioma Patients.
Traylor JI, Kuo JS> ;Neurosurgery.
A Roadmap for Aspiring Surgeon-Scientists in Today's Healthcare Environment.
Goldstein AM, Blair AB, Keswani SG, Gosain A, Morowitz M, Kuo JS, Levine M, Ahuja N, Hackam DJ, Basic Science Committee of the Society of University Surgeons> ;Annals of surgery.
Reduced H3K27me3 is a New Epigenetic Biomarker for Pediatric Posterior Fossa Ependymomas.
Zhang RR, Kuo JS> ;Neurosurgery.
3K3A-Activated Protein C and Implanted Neural Stem Cells Stimulate Repair and Functional Recovery After Ischemic Stroke.
Strebe JK, Lubin JA, Kuo JS> ;Neurosurgery.
Intracortical Microstimulation of Human Somatosensory Cortex Reproduces Touch in Spinal Cord Injury Patient.
Lubin JA, Strebe JK, Kuo JS> ;Neurosurgery.
Heparan Sulfates Promote Amyloid Pathology in Alzheimer Disease.
Zhang RR, Strebe JK, Kuo JS> ;Neurosurgery.
New Molecular Insights and Potential Therapies for Diffuse Intrinsic Pontine Glioma.
Zhang RR, Pointer KB, Kuo JS> ;Neurosurgery.
Oncolytic Herpes Simplex Virus Glioblastoma Therapy is Potentiated by Tumor Necrosis Factor-α Inhibition.
Pointer KB, Zhang RR, Kuo JS> ;Neurosurgery.
Ion transporters in brain tumors.
Cong D, Zhu W, Kuo JS, Hu S, Sun D> ;Current medicinal chemistry.
Fluorescent cancer-selective alkylphosphocholine analogs for intraoperative glioma detection.
Swanson KI, Clark PA, Zhang RR, Kandela IK, Farhoud M, Weichert JP, Kuo JS> ;Neurosurgery.
Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma.
Zhang RR, Pointer KB, Kuo JS, Dempsey RJ> ;Neurosurgery.
Myelin-forming cell-specific cadherin-19 is a marker for minimally infiltrative glioblastoma stem-like cells.
Zorniak M, Clark PA, Kuo JS> ;Journal of neurosurgery.
Alkylphosphocholine analogs for broad-spectrum cancer imaging and therapy.
Weichert JP, Clark PA, Kandela IK, Vaccaro AM, Clarke W, Longino MA, Pinchuk AN, Farhoud M, Swanson KI, Floberg JM, Grudzinski J, Titz B, Traynor AM, Chen HE, Hall LT,...> ;Science translational medicine.
Join now to see all

Journal Articles

Potential CAR T Cell Immunotherapy Against Diffuse Midline Gliomas
John Kuo, MD, Neurosurgery

Press Mentions

UW Study Uses 'Bio-Panning' to Find Human Antibodies for Brain Cancer Stem CellsNovember 27th, 2017
Coming Soon: Glow-in-the-Dark Cancer SurgeryJanuary 20th, 2017
Tumor-Targeting Agent Attaches to Cancer Cells: Study - US NewsJune 11th, 2014
Join now to see all